Research Topics
| G SaposnikSummaryAffiliation: St. Michael's Hospital Country: Canada Publications
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Detail Information
Publications
Pontine warning syndromeGustavo Saposnik
Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Ste 931, Toronto ONM5C1R6, Canada
Arch Neurol 65:1375-7. 2008..Little is known about stroke mechanisms in patients with fluctuating symptoms and the role of branch atherosclerotic disease...
Hospital volume and stroke outcome: does it matter?G Saposnik
Stroke Program, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, London, ON, Canada
Neurology 69:1142-51. 2007..Our aim was to determine whether facility type and hospital volume was associated with stroke mortality...
Do all age groups benefit from organized inpatient stroke care?Gustavo Saposnik
Stroke Research Unit, Division of Neurology, Department of Medicine, Stroke Outcome Research Canada, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Stroke 40:3321-7. 2009..We sought to determine whether the reduction in mortality or institutionalization seen with organized stroke care was similar across all age groups...
Stroke outcome in those over 80: a multicenter cohort study across CanadaGustavo Saposnik
South East Toronto Regional Stroke Center, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Stroke 39:2310-7. 2008..However, limited information is available about the burden of stroke in individuals over 80. We sought to evaluate differences in clinical outcomes in Canadians over 80 years old hospitalized for an acute ischemic stroke...
Variables associated with 7-day, 30-day, and 1-year fatality after ischemic strokeGustavo Saposnik
Stroke Research Unit, Division of Neurology, Department of Medicine, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Canada
Stroke 39:2318-24. 2008..However, limited information is available concerning variables associated with stroke case fatality at these different points in time. We sought to identify and compare variables associated with 7-day, 30-day, and 1-year stroke fatality...
Escalating levels of access to in-hospital care and stroke mortalityGustavo Saposnik
Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, M5C 1R6, Canada
Stroke 39:2522-30. 2008..However, limited information is available comparing different levels of organized care. Our aim was to determine whether escalating levels of organized care can improve stroke outcomes...
Stroke in the very elderly: hospital care, case fatality and dispositionGustavo Saposnik
Stroke Research Program, South East Toronto Regional Stroke Center, Division of Neurology, Department of Medicine, St Michael s Hospital, Ont, Canada
Cerebrovasc Dis 27:537-43. 2009..However, limited information is available about the burden of stroke in individuals over 90...
Socioeconomic status, hospital volume, and stroke fatality in CanadaGustavo Saposnik
Department of Medicine, Division of Neurology, Stroke Research Unit, South East Toronto Regional Stroke Center, St Michael sHospital, University of Toronto, Toronto, Canada
Stroke 39:3360-6. 2008..We sought to determine whether residence in a low-income neighborhood was associated with admission to low-volume facilities and whether this contributed to differences in fatality after stroke...
Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trialGustavo Saposnik
Department of Medicine, Division of Neurology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Stroke 40:1365-72. 2009..Our aim was to determine whether vitamin therapy reduces the risk of ischemic and hemorrhagic stroke, as well as stroke-related disability...
Applying the evidence: do patients with stroke, coronary artery disease, or both achieve similar treatment goals?Gustavo Saposnik
Division of Cardiology, Canadian Heart Research Centre and Terrence Donnelly Heart Centre, University of Toronto, Canada
Stroke 40:1417-24. 2009..We sought to evaluate and compare differences in treatment patterns and the attainment of current guideline-recommended targets in unselected high-risk ambulatory patients with CAD, CVD, or both...
Myocardial infarction associated with recency of immigration to OntarioG Saposnik
Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
QJM 103:253-8. 2010..OBJECTIve: To determine the risk of AMI among new immigrants compared to long-term residents, and, among those who develop AMI, their short- and long-term mortality rate...
Age disparities in stroke quality of care and delivery of health servicesGustavo Saposnik
Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Stroke 40:3328-35. 2009..Limited information is available on the effect of age on stroke management and care delivery. Our aim was to determine whether access to stroke care, delivery of health services, and clinical outcomes after stroke are affected by age...
IScore: a risk score to predict death early after hospitalization for an acute ischemic strokeGustavo Saposnik
Stroke Outcomes Research Centre, Stroke Outcome Research Canada Working Group, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, Canada
Circulation 123:739-49. 2011..Our aim was to identify predictors of mortality and to develop and validate a risk score model using information available at hospital presentation...
Effectiveness of Virtual Reality Exercises in STroke Rehabilitation (EVREST): rationale, design, and protocol of a pilot randomized clinical trial assessing the Wii gaming systemG Saposnik
Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario
Int J Stroke 5:47-51. 2010..EVREST was designed to evaluate feasibility, safety and efficacy of using the Nintendo Wii gaming virtual reality (VRWii) technology to improve arm recovery in stroke patients...
Risk of premature stroke in recent immigrants (PRESARIO): population-based matched cohort studyG Saposnik
Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, M5C 1R6, Canada
Neurology 74:451-7. 2010..We determined the risk of acute stroke associated with recency of immigration...
Effectiveness of virtual reality using Wii gaming technology in stroke rehabilitation: a pilot randomized clinical trial and proof of principleGustavo Saposnik
Division of Neurology, Departments of Medicine and Health Policy Management and Evaluation and Institute for Clinical Evaluative Sciences, Li Ka Shing Knowledge Institute of St Michael s Hospital, Dalla Lana, School of Public Health, University of Toronto, Ontario, Canada
Stroke 41:1477-84. 2010..Although existing evidence suggests that increasing intensity of stroke rehabilitation therapy results in better motor recovery, limited evidence is available on the efficacy of virtual reality for stroke rehabilitation...
In-hospital myocardial infarction following acute ischaemic stroke: an observational studyJ Liao
McMaster University, Hamilton, ON, Canada
Eur J Neurol 16:1035-40. 2009..Acute myocardial infarction is expected to be an important medical complication following ischaemic stroke. We sought to describe the frequency and clinical impact of in-hospital myocardial infarction following acute ischaemic stroke...
Impact of seizures on morbidity and mortality after stroke: a Canadian multi-centre cohort studyJ G Burneo
Epilepsy Programme, Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada
Eur J Neurol 17:52-8. 2010..Limited information is available about the impact of seizures on stroke outcome, health care delivery and resource utilization...
Weekends: a dangerous time for having a stroke?Gustavo Saposnik
Stroke Program, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, London, ON, Canada
Stroke 38:1211-5. 2007..However, limited information is available concerning the "weekend effect" on stroke mortality. Our aim was to evaluate the impact of weekend admissions on stroke mortality in different settings...
Gender differences in carotid imaging and revascularization following strokeM K Kapral
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Neurology 73:1969-74. 2009..Carotid endarterectomy is performed less often in women than in men, but it is unknown whether this reflects differences in screening rates, disease prevalence, or other factors...
Risk factors, inpatient care, and outcomes of pneumonia after ischemic strokeO Finlayson
University of Toronto, Toronto, Canada
Neurology 77:1338-45. 2011..Moreover, there is discrepancy in the literature regarding the impact of pneumonia on stroke outcomes...
Care and outcomes in patients with ischemic stroke with and without preexisting dementiaG Saposnik
Department of Medicine, University of Toronto, Toronto M5C 1R6, Canada
Neurology 77:1664-73. 2011..To describe clinical characteristics and evaluate processes of care and outcomes at discharge in patients with ischemic stroke with and without preexisting dementia...
Gastrointestinal bleeding after acute ischemic strokeM J O'Donnell
Henderson Research Centre, 70 Wing, Room 220, 711 Concession Street, Hamilton, Ontario, L8V 1C3, Canada
Neurology 71:650-5. 2008..We sought to describe the incidence, risk factors, and association with clinical outcomes of gastrointestinal bleeding following acute ischemic stroke...
Acute stroke with hyperdense middle cerebral artery sign benefits from IV rtPAM C Tartaglia
Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, London, ON, Canada
Can J Neurol Sci 35:583-7. 2008..The presence of a hyperdense middle cerebral artery sign (HMCAS) on pre-treatment head computed tomogram (CT) is considered a poor prognostic sign. We compared the clinical outcome in IV rtPA-treated patients with and without a HMCAS...
Optimizing discharge planning: clinical predictors of longer stay after recombinant tissue plasminogen activator for acute strokeGustavo Saposnik
Stroke Program, Department of Clinical Neurological Sciences and Southwestern Ontario Coordinated Stroke Strategy, London Health Science Center, The University of Western Ontario, London, Ontario, Canada
Stroke 36:147-50. 2005..Although studies have identified variables associated with LOS, few have analyzed predictors of longer stay after receiving thrombolytic therapy for acute stroke...
Predictors of major neurologic improvement after thrombolysis in acute strokeGustavo Saposnik
Department of Clinical Neurological Sciences, London Health Science Center, The University of Western Ontario, London, Ontario, Canada
Neurology 65:1169-74. 2005..Major neurologic improvement at 24 hours after administration of recombinant tissue plasminogen activator (rt-PA) in acute stroke may predict good outcome at 3 months...
The impact of lesion side on acute stroke treatmentSilvia Di Legge
Department of Clinical Neurological Sciences, London Health Science Centre, University of Western Ontario, Canada
Neurology 65:81-6. 2005..Only a small percentage of patients with acute stroke are treated with recombinant tissue plasminogen activator (rt-PA)...
Does a birthday predispose to vascular events?Gustavo Saposnik
Stroke Team, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, Ontario, Canada
Neurology 67:300-4. 2006..To examine the influence of birthdays on the onset and course of vascular events such as stroke, TIA, and acute myocardial infarction (AMI)...
The Canadian Neurological Scale and the NIHSS: development and validation of a simple conversion modelYongchai Nilanont
Division of Neurology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Cerebrovasc Dis 30:120-6. 2010..The CNS requires less extensive neurological evaluation and is quicker and simpler to administer...
Disparities in management patterns and outcomes of patients with non-ST-elevation acute coronary syndrome with and without a history of cerebrovascular diseaseTony C Lee
Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Am J Cardiol 105:1083-9. 2010....
Lack of improvement in patients with acute stroke after treatment with thrombolytic therapy: predictors and association with outcomeGustavo Saposnik
Stroke Program, Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, Canada
JAMA 292:1839-44. 2004..Few studies have analyzed outcome at 24 hours. An early and reliable prediction of poor outcome has implications for clinical management and discharge planning...
Association between weekend hospital presentation and stroke fatalityJiming Fang
Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, Canada
Neurology 75:1589-96. 2010..Previous studies have found higher stroke case fatality in patients admitted to the hospital on weekends compared to weekdays, but the reasons for this association are not known...
Predicting functional outcome after intra-arterial thrombolysis: aspects of ASPECTSGustavo Saposnik
Stroke 35:e7-8; author reply e7-8. 2004
Quality of ischemic stroke care in emerging countries: the Argentinian National Stroke Registry (ReNACer)Luciano A Sposato
Stroke Center, Neurosciences Institute at Favaloro Foundation, Buenos Aires, Argentina
Stroke 39:3036-41. 2008..Our aim was to explore the feasibility of measuring standardized indicators of quality of ischemic stroke care in acute care facilities in Argentina...
Neglecting the difference: does right or left matter in stroke outcome after thrombolysis?Silvia Di Legge
Stroke Unit, Università of Tor Vergata, Viale Oxford 81 00133 Rome, Italy
Stroke 37:2066-9. 2006..We analyzed outcomes after IV rt-PA with respect to the side of the affected hemisphere...
Stroke in South America: a systematic review of incidence, prevalence, and stroke subtypesGustavo Saposnik
Stroke Unit, Department of Neurology, Ramos Mejia Hospital, Buenos Aires University, Argentina
Stroke 34:2103-7. 2003..Because epidemiological and clinical characteristics of stroke vary according to regional factors, we need to know the peculiarities of stroke on this continent...
Spontaneous and reflex movements in 107 patients with brain deathGustavo Saposnik
The Movements in Brain Death Study Group, Department of Neurology, , Universidad de Buenos Aires, Argentina
Am J Med 118:311-4. 2005
Dissecting brain death: time for a new lookGustavo Saposnik
Neurology 70:1230-1. 2008
Poststroke care: chronicles of a neglected battleGustavo Saposnik
Stroke 38:1727-9. 2007
