J G Ray

Summary

Affiliation: St. Michael's Hospital
Country: Canada

Publications

  1. pmc Abdominal visceral adiposity in the first trimester predicts glucose intolerance in later pregnancy
    Aisling Mary Martin
    Department of Obstetrics and Gynecology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 32:1308-10. 2009
  2. ncbi request reprint Gestational prediabetes: a new term for early prevention?
    Joel G Ray
    Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Indian J Med Res 132:251-5. 2010
  3. pmc Metabolic syndrome features and risk of neural tube defects
    Joel G Ray
    Department of Medicine, St, Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, M5B 1W8, Canada
    BMC Pregnancy Childbirth 7:21. 2007
  4. ncbi request reprint Venous thromboembolism in association with features of the metabolic syndrome
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Ontario M5B 1W8, Canada
    QJM 100:679-84. 2007
  5. ncbi request reprint Lipid-lowering therapy and outcomes in heart failure
    Joel G Ray
    Department of Medicine, Divisions of General Internal Medicine and Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    J Cardiovasc Pharmacol Ther 12:27-35. 2007
  6. pmc Results of the Recent Immigrant Pregnancy and Perinatal Long-term Evaluation Study (RIPPLES)
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ont
    CMAJ 176:1419-26. 2007
  7. ncbi request reprint Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Epidemiology 18:362-6. 2007
  8. ncbi request reprint Homocysteine-lowering therapy and risk for venous thromboembolism: a randomized trial
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 146:761-7. 2007
  9. ncbi request reprint Brief overview of maternal triglycerides as a risk factor for pre-eclampsia
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    BJOG 113:379-86. 2006
  10. ncbi request reprint Greater maternal weight and the ongoing risk of neural tube defects after folic acid flour fortification
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada
    Obstet Gynecol 105:261-5. 2005

Detail Information

Publications100

  1. pmc Abdominal visceral adiposity in the first trimester predicts glucose intolerance in later pregnancy
    Aisling Mary Martin
    Department of Obstetrics and Gynecology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 32:1308-10. 2009
    ..To assess whether abdominal adiposity in early pregnancy is associated with a higher risk of glucose intolerance at a later gestational stage...
  2. ncbi request reprint Gestational prediabetes: a new term for early prevention?
    Joel G Ray
    Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Indian J Med Res 132:251-5. 2010
    ..In addition, early intervention could offset the need for resource-intense GDM management or insulin therapy...
  3. pmc Metabolic syndrome features and risk of neural tube defects
    Joel G Ray
    Department of Medicine, St, Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, M5B 1W8, Canada
    BMC Pregnancy Childbirth 7:21. 2007
    ..Whether they, in combination with additional features of MetSyn, alter this risk is not known. We evaluated the risk of NTD in association with maternal features of the MetSyn...
  4. ncbi request reprint Venous thromboembolism in association with features of the metabolic syndrome
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Ontario M5B 1W8, Canada
    QJM 100:679-84. 2007
    ..However, whether each of these factors additively increases the risk of VTE is uncertain...
  5. ncbi request reprint Lipid-lowering therapy and outcomes in heart failure
    Joel G Ray
    Department of Medicine, Divisions of General Internal Medicine and Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    J Cardiovasc Pharmacol Ther 12:27-35. 2007
    ..More data are needed before statins can be recommended in those with isolated heart failure...
  6. pmc Results of the Recent Immigrant Pregnancy and Perinatal Long-term Evaluation Study (RIPPLES)
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ont
    CMAJ 176:1419-26. 2007
    ..We tested whether the "healthy immigrant effect" extends to the risk of placental dysfunction during the short interval of pregnancy...
  7. ncbi request reprint Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Epidemiology 18:362-6. 2007
    ..Prior studies used relatively insensitive measures of B(12), did not adjust for folate levels, and were conducted in countries without folic acid food fortification. In Canada, flour has been fortified with folic acid since mid-1997...
  8. ncbi request reprint Homocysteine-lowering therapy and risk for venous thromboembolism: a randomized trial
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 146:761-7. 2007
    ..Elevated total homocysteine levels are associated with a higher risk for venous thromboembolism. Whether decreasing homocysteine levels with vitamin therapy reduces the risk for venous thromboembolism is not known...
  9. ncbi request reprint Brief overview of maternal triglycerides as a risk factor for pre-eclampsia
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    BJOG 113:379-86. 2006
    ..Features of the metabolic syndrome-maternal obesity, diabetes mellitus and chronic hypertension-are risk factors for pre-eclampsia...
  10. ncbi request reprint Greater maternal weight and the ongoing risk of neural tube defects after folic acid flour fortification
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada
    Obstet Gynecol 105:261-5. 2005
    ..Because overweight women may consume greater quantities of refined wheat flour, we questioned whether their risk of NTD changed after flour fortification...
  11. ncbi request reprint Statin use and survival outcomes in elderly patients with heart failure
    Joel G Ray
    Department of Medicine, St Michaels Hospital, University of Toronto, Ontario M5B 1W8, Canada
    Arch Intern Med 165:62-7. 2005
    ..Coronary artery disease is a leading cause of heart failure. Statins are efficacious drugs for the primary and secondary prevention of coronary heart disease, but their value in persons with heart failure remains unknown...
  12. ncbi request reprint Risk of congenital anomalies detected during antenatal serum screening in women with pregestational diabetes
    J G Ray
    Department of Medicine, Inner City Health Research Unit, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada
    QJM 97:651-3. 2004
    ..Most studies comparing women with and without pregestational diabetes mellitus have not systematically screened for fetal anomalies in early pregnancy, potentially leading to selection bias...
  13. pmc Breast size and risk of type 2 diabetes mellitus
    Joel G Ray
    Departments of Medicine, and the Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ont
    CMAJ 178:289-95. 2008
    ..We sought to evaluate whether a woman's breast size in late adolescence is associated with an increased risk of type 2 diabetes mellitus in adulthood...
  14. ncbi request reprint Cardiovascular health after maternal placental syndromes (CHAMPS): population-based retrospective cohort study
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada
    Lancet 366:1797-803. 2005
    ..Our aim was to assess the risk of premature vascular disease in women who had had a pregnancy affected by maternal placental syndromes...
  15. pmc Major radiodiagnostic imaging in pregnancy and the risk of childhood malignancy: a population-based cohort study in Ontario
    Joel G Ray
    Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    PLoS Med 7:e1000337. 2010
    ..The association between fetal exposure to major radiodiagnostic testing in pregnancy-computed tomography (CT) and radionuclide imaging-and the risk of childhood cancer is not established...
  16. pmc Maternal ethnicity and risk of neural tube defects: a population-based study
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario M5B 1WB, Canada
    CMAJ 171:343-5. 2004
    ..Maternal body mass and the presence of diabetes mellitus are probable risk factors for neural tube defects (NTDs). The association between maternal ethnicity and the risk of NTDs remains poorly understood, however...
  17. ncbi request reprint Efficacy of Canadian folic acid food fortification
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Food Nutr Bull 29:S225-30. 2008
    ..The current paper describes how this took place, and the epidemiological effects that occurred in the Canadian population, including higher blood folate levels and a decline in the prevalence of neural tube defects...
  18. ncbi request reprint Hyperhomocysteinemia: no longer a consideration in the management of venous thromboembolism
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Curr Opin Pulm Med 14:369-73. 2008
    ..To determine whether clinicians should continue to screen for or treat hyperhomocysteinemia among individuals with venous thromboembolism...
  19. doi request reprint High rate of maternal vitamin B12 deficiency nearly a decade after Canadian folic acid flour fortification
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    QJM 101:475-7. 2008
    ..4 (1.1-1.8) after 28 days gestation. About 1 in 20 women may be deficient in B12 in early pregnancy. The impact on maternal and fetal well-being, including preventable NTD, should be considered...
  20. pmc Alcohol sales and risk of serious assault
    Joel G Ray
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    PLoS Med 5:e104. 2008
    ..We assessed the risk of being hospitalized due to assault in association with retail alcohol sales across Ontario...
  21. ncbi request reprint Myocardial infarction associated with recency of immigration to Ontario
    G Saposnik
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    QJM 103:253-8. 2010
    ..New immigrants to North America exhibit lower rates of obesity and hypertension than their native-born counterparts. Whether this is reflected by a lower relative risk of acute myocardial infarction (AMI) is not known...
  22. ncbi request reprint Maternal and neonatal outcomes in pregestational and gestational diabetes mellitus, and the influence of maternal obesity and weight gain: the DEPOSIT study. Diabetes Endocrine Pregnancy Outcome Study in Toronto
    J G Ray
    Department of Medicine, University of Toronto, Canada
    QJM 94:347-56. 2001
    ....
  23. ncbi request reprint Persistence of vitamin B12 insufficiency among elderly women after folic acid food fortification
    J G Ray
    Department of Medicine, Sunnybrook and Women s College Health Science Centre, Toronto, Ontario, Canada
    Clin Biochem 36:387-91. 2003
    ..To estimate the associated risk of folate and vitamin B12 (B12) insufficiency, as well as vitamin repletion, following folic acid food fortification...
  24. ncbi request reprint Declining rate of folate insufficiency among adults following increased folic acid food fortification in Canada
    J G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, ON
    Can J Public Health 93:249-53. 2002
    ..We investigated whether the rate of folate and vitamin B12 insufficiency among adults has changed since this mandatory fortification program was implemented...
  25. ncbi request reprint Deep vein thrombosis and its prevention in critically ill adults
    J Attia
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Arch Intern Med 161:1268-79. 2001
    ..More potent prophylactic regimens other than unfractionated or low-molecular-weight heparins alone may be needed with higher-risk groups...
  26. doi request reprint Vitamin B-12 and neural tube defects: the Canadian experience
    Miles D Thompson
    Department of Laboratory Medicine and Pathobiology, Banting Institute, University of Toronto, Toronto, ON, Canada
    Am J Clin Nutr 89:697S-701S. 2009
    ..A multicenter randomized controlled trial comparing periconceptional vitamin B-12 in combination with FA against FA alone is warranted...
  27. doi request reprint Risk of premature stroke in recent immigrants (PRESARIO): population-based matched cohort study
    G Saposnik
    Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, M5C 1R6, Canada
    Neurology 74:451-7. 2010
    ..We determined the risk of acute stroke associated with recency of immigration...
  28. ncbi request reprint Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies
    J G Ray
    Department of Medicine, Women s College Campus, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
    Pathophysiol Haemost Thromb 32:51-8. 2002
    ..We conducted a meta-analysis of previously published studies to clarify the role of the MTHFR 677 TT homozygous genotype in association with VTE...
  29. ncbi request reprint Maternal and newborn outcomes among women with schizophrenia: a retrospective population-based cohort study
    S N Vigod
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada Women s College Research Institute, University of Toronto, Toronto, Ontario, Canada Institute for Clinical and Evaluative Sciences, Toronto, Ontario, Canada
    BJOG 121:566-74. 2014
    ..We aimed to quantify maternal and newborn health outcomes among women with schizophrenia...
  30. ncbi request reprint Association between folic acid food fortification and hypertension or preeclampsia in pregnancy
    Joel G Ray
    Toronto, Ontario
    Arch Intern Med 162:1776-7. 2002
  31. ncbi request reprint Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus: a meta-analysis
    J G Ray
    Division of Obstetrical Medicine, Department of Medicine, Women s College Campus, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    QJM 94:435-44. 2001
    ....
  32. ncbi request reprint Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review
    J G Ray
    Obstetrical Medicine Programme, Department of Medicine, University of Toronto, Ontario
    Placenta 20:519-29. 1999
    ....
  33. doi request reprint Risk of stillbirth at extremes of birth weight between 20 to 41 weeks gestation
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    J Perinatol 32:829-36. 2012
    ..To determine the risk of stillbirth between 20 to 41 weeks gestation, at highly detailed weight percentiles, including extreme degrees of small (SGA) and large (LGA) for gestational age birth weight...
  34. doi request reprint Sex-specific basis of severe placental dysfunction leading to extreme preterm delivery
    M G Walker
    Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    Placenta 33:568-71. 2012
    ....
  35. ncbi request reprint Paroxysmal nocturnal hemoglobinuria and the risk of venous thrombosis: review and recommendations for management of the pregnant and nonpregnant patient
    J G Ray
    Department of Medicine, and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Haemostasis 30:103-17. 2000
    ....
  36. ncbi request reprint MOS HIP: McMaster outcome study of hypertension in pregnancy
    J G Ray
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Early Hum Dev 64:129-43. 2001
    ..The risk of developing these outcomes among women with either preeclampsia or chronic hypertension, relative to those with gestational hypertension, is not known...
  37. ncbi request reprint Platelet count may predict abnormal bleeding time among pregnant women with hypertension and preeclampsia
    R J McDonagh
    Department of Obstetrics and Gynecology, St Joseph s Hospital and McMaster University, Hamilton, Ontario, Canada
    Can J Anaesth 48:563-9. 2001
    ..Many rely on the bleeding time (BT) in making this determination. We examined whether the platelet count can adequately predict BT among a group of hypertensive parturients...
  38. ncbi request reprint Suspected pulmonary embolism in pregnancy: clinical presentation, results of lung scanning, and subsequent maternal and pediatric outcomes
    W S Chan
    Department of Medicine, Women s College Campus, Sunnybrook and Women s College Health Sciences Centre, 76 Grenville St, Toronto, Ontario, Canada M5S 1B2
    Arch Intern Med 162:1170-5. 2002
    ..Ventilation-perfusion (VQ) scanning is used when pulmonary embolism (PE) is suspected during pregnancy; however, the distribution of lung scan results and safety of VQ scanning have never been studied...
  39. ncbi request reprint Randomized clinical trial of homocysteine level lowering therapy and fractures
    Anna M Sawka
    Toronto General Hospital, 200 Elizabeth St, 12 212 Eaton North, Toronto, Ontario M5G 2C4, Canada
    Arch Intern Med 167:2136-9. 2007
  40. ncbi request reprint Metabolic syndrome and the risk of placental dysfunction
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, ON
    J Obstet Gynaecol Can 27:1095-101. 2005
    ..However, the relationship between the metabolic syndrome and the future risk of PD or fetal demise is unknown...
  41. ncbi request reprint Do we care if statins prevent venous thromboembolism?
    J G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, ON, Canada
    J Thromb Haemost 2:695-6. 2004
  42. pmc "You're not my obstetrician" (and it may not matter)
    Chaim M Bell
    Department of Medicine, University of Toronto, Toronto, Ont
    CMAJ 177:372-3. 2007
  43. ncbi request reprint Association of neural tube defects and folic acid food fortification in Canada
    Joel G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Lancet 360:2047-8. 2002
    ..58 per 1000 pregnancies thereafter (prevalence ratio 0.52, 95% CI 0.40-0.67, p<0.0001). At a population level, folic acid food fortification is associated with a pronounced reduction in open neural tube defects...
  44. doi request reprint Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial
    Gustavo Saposnik
    Department of Medicine, Division of Neurology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 40:1365-72. 2009
    ..Our aim was to determine whether vitamin therapy reduces the risk of ischemic and hemorrhagic stroke, as well as stroke-related disability...
  45. pmc Bias in published cost effectiveness studies: systematic review
    Chaim M Bell
    St Michael s Hospital, Toronto, Ontario, Canada M5B 1W8
    BMJ 332:699-703. 2006
    ....
  46. doi request reprint Chronic dialysis and death among survivors of acute kidney injury requiring dialysis
    Ron Wald
    Division of Nephrology, St Michael s Hospital, 61 Queen St East, 9 140, Toronto, ON M5C 2T2, Canada
    JAMA 302:1179-85. 2009
    ..Severe acute kidney injury among hospitalized patients often necessitates initiation of short-term dialysis. Little is known about the long-term outcome of those who survive to hospital discharge...
  47. ncbi request reprint Maternal body mass index and the risk of preeclampsia: a systematic overview
    Tara E O'Brien
    Division of Obstetrical Medicine, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Epidemiology 14:368-74. 2003
    ..We performed a systematic overview of the literature to determine the association between prepregnancy body mass index and the risk of preeclampsia...
  48. ncbi request reprint Folic acid food fortification in Canada
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Nutr Rev 62:S35-9. 2004
    ..The current report outlines some of the changes to the health status of Canadians in relation to its folic acid food fortification initiative...
  49. ncbi request reprint Association between Bell's palsy in pregnancy and pre-eclampsia
    D Shmorgun
    Department of Medicine, Sunnybrook and Women s College Health Science Centre, Toronto, Ontario, Canada
    QJM 95:359-62. 2002
    ..Study design: Case series study of consecutive female patients...
  50. ncbi request reprint Vitamin B12 insufficiency and the risk of fetal neural tube defects
    J G Ray
    Division of Obstetrical Medicine, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    QJM 96:289-95. 2003
    ..Although maternal folate insufficiency is a risk factor for fetal neural tube defects (NTDs), there is controversy about whether vitamin B12 (B12) insufficiency is also associated with an increased risk of NTDs...
  51. ncbi request reprint Antipsychotic and antidepressant drug use in the elderly and the risk of venous thromboembolism
    Joel G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario
    Thromb Haemost 88:205-9. 2002
    ..Preliminary evidence suggests that use of antipsychotic drugs is associated with an increased risk of venous thromboembolism...
  52. ncbi request reprint Prevalence of trisomy 21 following folic acid food fortification
    Joel G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada
    Am J Med Genet A 120:309-13. 2003
    ..24). In conclusion, we failed to observe a decline in the occurrence of trisomy 21 following folic acid food fortification...
  53. ncbi request reprint Maternal obesity and the risk of placental vascular disease
    Taryn Becker
    Department of Medicine, Division of Endocrinology and Metabolism, University of Toronto, Toronto ON
    J Obstet Gynaecol Can 30:1132-6. 2008
    ..While elevated maternal weight in early pregnancy is associated with a higher rate of preeclampsia, the risk of placental abruption and placental infarction is unknown...
  54. pmc Adverse perinatal outcomes associated with homelessness and substance use in pregnancy
    Merry Little
    Department of Obstetrics and Gynecology, St Michael s Hospital, University of Toronto, Toronto, Ont
    CMAJ 173:615-8. 2005
    ..We undertook a study to provide preliminary estimates of the risk of adverse perinatal outcomes among Canadian women who are homeless or marginally housed during pregnancy, and the effect of concomitant substance use...
  55. ncbi request reprint Estimating gestational age at birth: a population-based derivation-validation study
    M L Urquia
    Centre for Research on Inner City Health, The Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada
    Chronic Dis Inj Can 31:103-8. 2011
    ..We developed and validated a GA prediction model for singleton births for use in epidemiological studies...
  56. pmc Giant cell arteritis and cardiovascular disease in older adults
    J G Ray
    Department of Medicine, Inner City Health, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8
    Heart 91:324-8. 2005
    ..To explore the association between giant cell arteritis (GCA) and subsequent cardiovascular disease in older adults...
  57. ncbi request reprint Anticonvulsant drug use and low bone mass in adults with neurodevelopmental disorders
    J G Ray
    Sunnybrook and Women s College Health Science Centre, Toronto, Canada
    QJM 95:219-23. 2002
    ..Use of anticonvulsant drugs among adults with neurodevelopmental disorders may be an important risk factor for both osteoporosis and skeletal fractures...
  58. ncbi request reprint Use of statins and the subsequent development of deep vein thrombosis
    J G Ray
    Department of Medicine, Institute for Clinical Evaluative Sciences, University of Toronto, Ontario
    Arch Intern Med 161:1405-10. 2001
    ..Some of the benefit of statins for the prevention of cardiovascular disease may be due to their antithrombotic properties. Little is known about the effect of these drugs on the development of deep vein thrombosis...
  59. ncbi request reprint Survey of cardiac surgeons' perceptions of the addition of ASA to warfarin for patients with mechanical heart valves
    J G Ray
    Department of Medicine, McMaster University, Hamilton, Ontario
    Can J Cardiol 13:1162-5. 1997
    ..Most surgeons avoid ASA out of concern for the increased risk of hemorrhage and a belief that there is no benefit. These perceptions are not supported by recent scientific data, however...
  60. doi request reprint Recruitment of immigrant and ethnic minorities in primary prevention trials of cardiovascular disease
    R S Minocher Homji
    Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
    QJM 104:469-76. 2011
    ..Accordingly, the absolute and relative benefits of CVD prevention strategies evaluated in randomized clinical trials (RCTs) may differ by the ethnic and immigrant composition of study participants...
  61. ncbi request reprint Folic acid food fortification is associated with a decline in neuroblastoma
    Amy E French
    Motherrisk Program and Division of Hematology and Oncology, The Hospital for Sick Children, and Department of Medicine and Prehospital Care Programme, Sunnybrook and Women s College Health Sciences Center, University of Toronto, Ontario, Canada
    Clin Pharmacol Ther 74:288-94. 2003
    ..In January 1997, Canada began fortifying flour with folic acid for the prevention of neural tube defects. The effect of folic acid fortification on the rate of neuroblastoma in offspring is not known...
  62. ncbi request reprint Dyslipidemia, statins, and venous thromboembolism: a potential risk factor and a potential treatment
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Curr Opin Pulm Med 9:378-84. 2003
    ..Until then, the efficacy of statins for the prevention or treatment of venous thromboembolism remains uncertain...
  63. ncbi request reprint Why might statins prevent venous thromboembolism: what needs to be done to know more?
    Joel G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Expert Opin Investig Drugs 11:1659-68. 2002
    ..The current review outlines the cumulative evidence from both the basic and epidemiologic sciences for why this might be so and offers some directions for future research...
  64. ncbi request reprint Pre-conceptional folic acid supplement use according to maternal country of birth
    Alice Han
    Faculty of Medicine, Department of Family and Community Medicine, University of Toronto, and Department of Obstetrics and Gynaecology, St Michael s Hospital, Toronto, ON
    J Obstet Gynaecol Can 31:222-6. 2009
    ..In Canada, the risk of NTD may differ across certain ethnic groups. It is not known whether pre-conceptional folic acid supplement use varies according to a woman's country of birth or her duration of residency in Canada...
  65. ncbi request reprint Elevated risk factors for adverse pregnancy outcomes among Filipina-Canadian women
    Esme Fuller-Thomson
    Factor Inwentash Faculty of Social Work, Department of Family and Community Medicine, University of Toronto, Toronto, ON
    J Obstet Gynaecol Can 32:113-9. 2010
    ....
  66. ncbi request reprint Association between folic acid food fortification and congenital orofacial clefts
    Joel G Ray
    Department of Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada
    J Pediatr 143:805-7. 2003
    ..15 per 1000) to after (1.21 per 1000) food fortification (prevalence ratio, 1.06; 95% confidence interval, 0.86-1.30)...
  67. pmc Proliferation of prenatal ultrasonography
    John J You
    Department of Medicine, McMaster University, Hamilton, Ontario
    CMAJ 182:143-51. 2010
    ..The extent to which temporal increases in the use of prenatal ultrasonography reflect changes in maternal risk is unknown. In this population-based study, we examined the use of prenatal ultrasonography from 1996 to 2006 in Ontario...
  68. ncbi request reprint Pilot study of the accuracy of bedside glucometry in the intensive care unit
    J G Ray
    Division of Critical Care, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Crit Care Med 29:2205-7. 2001
    ....
  69. pmc Sample size estimation for the sorcerer's apprentice. Guide for the uninitiated and intimidated
    J G Ray
    Department of Medicine, Women s College Hospital, Ont
    Can Fam Physician 45:1732-9. 1999
    ..To review the importance of and practical application of sample size determination for clinical studies in the primary care setting...
  70. ncbi request reprint Dose-reducing H2 receptor antagonists in the presence of low glomerular filtration rate: a systematic review of the evidence
    J Manlucu
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Nephrol Dial Transplant 20:2376-84. 2005
    ..While it is recommended that H2 receptor antagonists (H2RAs) be dose reduced in the presence of low glomerular filtration rate (GFR), in practice such adjustments often do not occur. We reviewed the evidence for this recommendation...
  71. pmc Newly diagnosed diabetes mellitus as a risk factor for serious liver disease
    Liane Porepa
    Department of Medicine, University of Toronto, The Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario
    CMAJ 182:E526-31. 2010
    ..We evaluated whether adults with newly diagnosed diabetes were at increased risk of serious liver disease...
  72. ncbi request reprint Thresholds for small for gestational age among newborns of East Asian and South Asian ancestry
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    J Obstet Gynaecol Can 31:322-30. 2009
    ..To determine the risk that newborn infants of East Asian and South Asian ancestry may be misclassified as small for gestational age (SGA)...
  73. pmc Motor vehicle crashes in diabetic patients with tight glycemic control: a population-based case control analysis
    Donald A Redelmeier
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    PLoS Med 6:e1000192. 2009
    ..We studied the association between glycosylated hemoglobin (HbA1c) and the risk of a motor vehicle crash using a population-based case control analysis...
  74. ncbi request reprint Use of maternal GHb concentration to estimate the risk of congenital anomalies in the offspring of women with prepregnancy diabetes
    Andrea Guerin
    Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Diabetes Care 30:1920-5. 2007
    ..We sought to determine the absolute risk of having a congenital anomaly in relation to periconceptional GHb concentration among women with prepregnancy diabetes...
  75. ncbi request reprint Estimating the prevalence of renal insufficiency in seniors requiring long-term care
    Amit X Garg
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 65:649-53. 2004
    ..The objective of this study was to estimate the prevalence of low glomerular filtration rate (GFR) in a large sample of elderly adults living in long-term care facilities, and to compare two commonly used methods for estimating GFR...
  76. pmc Taking ACE inhibitors during early pregnancy: is it safe?
    Joel G Ray
    Department of Medicine, University of Toronto, Toronto, Canada
    Can Fam Physician 53:1439-40. 2007
    ..We believe this study had serious limitations that preclude drawing any conclusions at present...
  77. ncbi request reprint Evidence for suboptimal use of periconceptional folic acid supplements globally
    Joel G Ray
    Inner City Health Programme, Department of Medicine, St Michael s Hospital, University of Toronto, Ontario, Canada
    BJOG 111:399-408. 2004
    ....
  78. ncbi request reprint Prepregnancy diabetes and risk of placental vascular disease
    Taryn Becker
    Division of Endocrinology and Metabolism, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 30:2496-8. 2007
  79. ncbi request reprint Primary and secondary prevention of heart failure with statins
    Jacob A Udell
    University of British Columbia, Department of Medicine, Vancouver Hospital and Health Sciences Centre, 2775 Laurel Street, Vancouver, British Columbia, V5Z 1M9, Canada
    Expert Rev Cardiovasc Ther 4:917-26. 2006
    ....
  80. ncbi request reprint Disequilibrium between admitted and discharged hospitalized patients affects emergency department length of stay
    Marian J Vermeulen
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Ann Emerg Med 54:794-804. 2009
    ..We test whether the balance between daily hospital admissions and discharges affects next-day ED length of stay...
  81. pmc Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel
    Joel G Ray
    Division of Critical Care, Department of Medicine, McMaster University, Hamilton, Canada
    BMC Cardiovasc Disord 3:3. 2003
    ..We evaluated the associated risk between the combined use of aspirin and clopidogrel and the transfusion of blood products perioperatively...
  82. doi request reprint Venous thromboembolism as a marker of quality of care in trauma
    Khumar Huseynova
    Trauma Program, Division of General Surgery, St Michael s Hospital, University of Toronto, Toronto, Canada
    J Am Coll Surg 208:547-52, 552.e1. 2009
    ..We explored the variation in VTE rates across trauma centers to determine its use as a measure of the quality of patient care...
  83. ncbi request reprint Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    William H Geerts
    Thromboembolism Program, Sunnybrook and Women s College Health Sciences Centre, Room D674, 2075 Bayview Ave, Toronto, ON, Canada M4N 3M5
    Chest 126:338S-400S. 2004
    ..We recommend, on admission to the intensive care unit, all patients be assessed for their risk of VTE. Accordingly, most patients should receive thromboprophylaxis (Grade 1A)...
  84. pmc Cobalamin deficiency in elderly patients
    Joel G Ray
    CMAJ 172:448-50; author reply 451. 2005
  85. ncbi request reprint Absence of effect of folic acid flour fortification on anticonvulsant drug levels
    Joel G Ray
    Am J Med 118:444-5. 2005
  86. pmc Statins and the risk of idiopathic venous thromboembolism
    Joel G Ray
    Br J Clin Pharmacol 56:460; author reply 461-2. 2003
  87. ncbi request reprint Folic acid and placental pathology
    Sarah D McDonald
    Epidemiology 16:419-20. 2005
  88. ncbi request reprint Increased red cell folate concentrations in women of reproductive age after Canadian folic acid food fortification
    Joel G Ray
    Epidemiology 13:238-40. 2002
  89. pmc Vitamin B12 and homocysteine
    Joel G Ray
    CMAJ 173:1359-60. 2005
  90. doi request reprint Acanthosis nigricans among women with gestational diabetes mellitus and risk of adverse pregnancy outcomes
    Julie Daitchman
    Diabetes Care 31:e30. 2008
  91. ncbi request reprint Trends in obesity in pregnancy
    Joel G Ray
    Epidemiology 18:280-1. 2007
  92. doi request reprint Retinal vein occlusion and traditional risk factors for atherosclerosis
    Paul R A O'Mahoney
    School of Medicine, Royal College of Surgeons in Ireland, Dublin
    Arch Ophthalmol 126:692-9. 2008
    ..To determine whether retinal vein occlusion (RVO) is related to systemic hypertension, diabetes mellitus, and hyperlipidemia...
  93. pmc Sale of kava extract in some health food stores
    Edward Mills
    CMAJ 169:1158-9. 2003
    ..Two months after the ban, 17 (57%) of 30 stores continued to sell kava. These findings demonstrate that health food stores may need to be better informed about the sale of restricted natural health products...
  94. ncbi request reprint Risk of fetal death associated with maternal drug dependence and placental abruption: a population-based study
    Sarah D McDonald
    Department of Obstetrics and Gynecology, McMaster University, Hamilton ON
    J Obstet Gynaecol Can 29:556-9. 2007
    ..Our objective was to examine the effect of maternal drug dependence on placental abruption and on fetal death in association with abruption and independent of it...
  95. ncbi request reprint Antifibrinolytics may be cost saving among recent recipients of combined acetylsalicylic acid and clopidogrel who undergo coronary artery bypass graft surgery
    Joel G Ray
    Can J Cardiol 20:829-30. 2004
  96. ncbi request reprint Newspaper reporting of screening mammography
    Joel G Ray
    Ann Intern Med 137:373-4. 2002
  97. ncbi request reprint Prophylaxis for the thromboembolic disease--recommendations from the American College of Chest Physicians--are they appropriate for orthopaedic surgery?
    Clifford W Colwell
    J Arthroplasty 21:148-9; author reply 149. 2006
  98. ncbi request reprint Prevention of venous thromboembolism
    William Geerts
    Chest 128:3775-6. 2005
  99. ncbi request reprint Long-term health sequelae following E. coli and campylobacter contamination of municipal water. Population sampling and assessing non-participation biases
    Amit X Garg
    Division of Nephrology, University of Western Ontario, London, Ontario
    Can J Public Health 96:125-30. 2005
    ..We explored whether the association between the acute exposure and preliminary long-term health outcomes may have been biased through differences between early- and late-recruited study participants...
  100. ncbi request reprint Westermark sign and suspected pulmonary embolism
    Joel G Ray
    Can J Cardiol 19:317; author reply 317. 2003