Research Topics
| G V Ramesh PrasadSummaryAffiliation: St. Michael's Hospital Country: Canada Publications
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Detail Information
Publications
Seasonal variation in outpatient blood pressure in stable renal transplant recipientsG V Prasad
Division of Nephrology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario
Transplantation 72:1792-4. 2001..This effect is independent of known predictors of hypertension in this population and may be, at least, partly related to changes in length of daylight and temperature...
A prospective observational study of changes in renal function and cardiovascular risk following living kidney donationG V Ramesh Prasad
Division of Nephrology, University of Toronto, St Michael s Hospital, Toronto, ON, Canada
Transplantation 86:1315-8. 2008..In summary, living kidney donation in the short term is safe. We suggest further observation of individuals with lower glomerular filtration rate for possible increased cardiovascular risk factors in the future...- Microalbuminuria post-renal transplantation: relation to cardiovascular risk factors and C-reactive proteinG V Ramesh Prasad
University of Toronto, Renal Transplant Program, St Michaels Hospital, Toronto, ON, Canada
Clin Transplant 23:313-20. 2009..938 (1.023-3.672), p = 0.042]. Post-transplant microalbuminuria is prevalent and is associated with elevated CRP, elevated BP, and smoking. Its relationship to these factors suggests it may be an indicator of graft and patient health... - Twenty four-hour ambulatory blood pressure profiles 12 months post living kidney donationG V Ramesh Prasad
University of Toronto, Division of Nephrology, St Michael s Hospital, Toronto, ON, Canada
Transpl Int 23:771-6. 2010..036). OGTT and lipid profiles remained normal in both groups. Predonation nocturnal nondipping does not carry adverse postdonation consequences over 12 months... - A quality of life comparison in cyclosporine- and tacrolimus-treated renal transplant recipients across CanadaG V Ramesh Prasad
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Ontario Canada
J Nephrol 23:274-81. 2010..Many Canadian renal transplant recipients receive either cyclosporine or tacrolimus as a long-term immunosuppressive agent. We investigated the effect of these drugs on quality of life (QoL) in Canadian transplant recipients... 
South Asian ethnicity as a risk factor for major adverse cardiovascular events after renal transplantationG V Ramesh Prasad
University of Toronto, Renal Transplant Program, St Michael s Hospital, 61 Queen Street East, 9th Floor, Toronto, ON, Canada M5C 2T2
Clin J Am Soc Nephrol 6:204-11. 2011..South Asians (SAs) comprise 25% of all Canadian visible minorities. SAs constitute a group at high risk for cardiovascular disease in the general population, but the risk in SA kidney transplant recipients has never been studied...- The role of dietary cations in the blood pressure of renal transplant recipientsG V Ramesh Prasad
Renal Transplant Program, St Michael s Hospital, Toronto, ON, Canada
Clin Transplant 20:37-42. 2006.... - Minimal change disease in association with fire coral (Millepora species) exposureG V Ramesh Prasad
Division of Nephrology, Department of Medicine, St Michael s Hospital, University of Toronto, Ontario, Canada
Am J Kidney Dis 47:e15-6. 2006..Physicians, particularly those in scuba-diving areas, should consider minimal change disease in exposed patients with proteinuria because a prompt diagnostic and therapeutic approach may potentially limit complications... - Role of dietary salt intake in posttransplant hypertension with tacrolimus-based immunosuppressionG V R Prasad
University of Toronto, Renal Transplant Program, St Michael s Hospital, Toronto, Ontario, Canada
Transplant Proc 37:1896-7. 2005..05 for each). In conclusion, there is no appreciable influence of dietary salt intake on BP under tacrolimus-based immunosuppression. Restricting dietary salt intake in these patients cannot be recommended at the current time... - Reduced incidence of new-onset diabetes mellitus after renal transplantation with 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors (statins)G V Ramesh Prasad
Division of Nephrology, Department of Medicine, University of Toronto, 61 Queen Street East, 9th Floor, Toronto, ON M5C 2T2, Canada
Am J Transplant 4:1897-903. 2004..02, HR 1.230[1.023-1.480]) and age > or =45 years (p = 0.01, HR 2.226[1.162-4.261]) were associated with increased diabetes. Statin use is associated with reduced new-onset diabetes development after renal transplantation... - Rhabdomyolysis due to red yeast rice (Monascus purpureus) in a renal transplant recipientG V Ramesh Prasad
Division of Nephrology, Department of Medicine, St Michael s Hospital, University of Toronto, 61 Queen Street East, 9th Floor, Toronto, Ontario M5C 2T2 Canada
Transplantation 74:1200-1. 2002..Transplant recipients must be cautioned against using herbal preparations to lower their lipid levels to prevent such complications from occurring... - Blood pressure reduction with HMG-CoA reductase inhibitors in renal transplant recipientsG V Ramesh Prasad
Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Kidney Int 63:360-4. 2003..The effect of statin therapy on blood pressure has not been previously examined in renal transplant recipients... - Angiotensinogen M235T genotype predicts progression in chronic renal allograft dysfunctionG V Ramesh Prasad
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Transplantation 75:209-16. 2003..Genotypes of the renin-angiotensin system have been implicated in essential hypertension and in progression of native kidney diseases, but gene effects on progression in chronic renal allograft dysfunction are unclear... - A prospective study of the physician effect on blood pressure in renal-transplant recipientsG V Ramesh Prasad
Division of Nephrology, Department of Medicine, St Michael s Hospital, 61 Queen Street East, 9th Floor, Toronto, Ontario M5C 2T2, Canada
Nephrol Dial Transplant 18:996-1000. 2003..Physician presence results in elevated blood pressure (BP) in the general population. The determinants of this phenomenon in renal-transplant recipients are not known... - Renal transplant recipient attitudes toward steroid use and steroid withdrawalG V Ramesh Prasad
Division of Nephrology, Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
Clin Transplant 17:135-9. 2003..Demographic data may be used to predict prednisone-related side-effects and guide steroid use in this population. Study designs related to steroid withdrawal should account for patient preferences in this context... - A numerical scale comparison of renal transplant recipient experience with and opinions about calcineurin inhibitorsG V Ramesh Prasad
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Ont, Canada
Nephron Clin Pract 97:c35-40. 2004..Many studies compare the relative benefits of cyclosporine and tacrolimus with respect to graft and patient outcomes, but comparative renal transplant recipient opinion on calcineurin inhibitor (CI) use has not been directly sought... - Pre-transplantation glucose testing for predicting new-onset diabetes mellitus after renal transplantationG V Ramesh Prasad
Division of Nephrology, University of Toronto, Toronto, ON, Canada
Clin Nephrol 71:140-6. 2009..However, NODAT risk based on pre-transplant blood glucose (BG) levels has not been defined. Our goal was to identify the best pre-transplant testing method and cut-off values... - A comparison of the effects of C2-cyclosporine and C0-tacrolimus on renal function and cardiovascular risk factors in kidney transplant recipientsS Joseph Kim
Division of Nephrology, University of Toronto, Toronto, Ontario, Canada
Transplantation 82:924-30. 2006..However, MAP, TC, and the risk of NODM were comparable in both treatment/monitoring groups. The long-term impact of short-term reductions in eGFR as a function of the type of treatment/monitoring strategy requires further study... - Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donationAnn Young
Division of Nephrology, University of Western Ontario, London, Ontario, Canada
Am J Kidney Dis 59:761-9. 2012..Living kidney donation offers a unique setting to study changes in phosphate and vitamin D homeostasis attributable to mild isolated decreases in estimated glomerular filtration rate (eGFR)... - Fracture risk in living kidney donors: a matched cohort studyAmit X Garg
Division of Nephrology, Department of Medicine, Western University, London, Canada
Am J Kidney Dis 59:770-6. 2012..Living kidney donors lose 50% of their renal mass and show changes in calcium homeostasis. We studied whether living kidney donation increases the risk of fragility fracture... - Association of uric acid with inflammation, progressive renal allograft dysfunction and post-transplant cardiovascular riskFarah Bandukwala
Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Am J Cardiol 103:867-71. 2009..Further studies are needed to establish its role in post-transplantation cardiovascular disease... - Hypertension in dialysis and kidney transplant patientsG V Ramesh Prasad
Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Canada
Can J Cardiol 25:309-14. 2009.... - Outcomes of commercial renal transplantation: a Canadian experienceG V Ramesh Prasad
Division of Nephrology, Department of Medicine, University of Toronto, Renal Transplant Program, St. Michael's Hospital, Toronto, Ontario, Canada
Transplantation 82:1130-5. 2006..CONCLUSION: Patients considering this method of acquiring live-donated kidneys should be counseled of the inherent risks and possible adverse outcomes including diminished dialysis-free survival... - Framingham risk score and novel cardiovascular risk factors underpredict major adverse cardiac events in kidney transplant recipientsSamuel A Silver
Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada
Transplantation 92:183-9. 2011..Framingham Risk Score (FRS) is an insufficient cardiovascular event predictor in unselected kidney transplant recipients. Its role in different risk subgroups and the value of adding novel risk factor candidates to FRS is unknown... - Acute dialysis risk in living kidney donorsNgan Lam
Department of Medicine, Division of Nephrology, University of Western Ontario, London, Canada
Nephrol Dial Transplant 27:3291-5. 2012..Reduced kidney function confers a higher risk of acute kidney injury at the time of an inciting event, such as sepsis. Whether the same is true in those with reduced renal mass from living kidney donation is unknown... - Mycophenolate mofetil and C-reactive protein in renal transplant recipientsBrian M Wong
Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Canada
Transplantation 83:48-53. 2007..Little is known about the effects of immunosuppressive and cardiovascular risk-modifying drugs on CRP in renal transplant recipients... - Accepting kidneys from older living donors: impact on transplant recipient outcomesA Young
Division of Nephrology, University of Western Ontario, Canada
Am J Transplant 11:743-50. 2011..29 (0.80-2.08)]. In light of an observed trend towards potential differences beyond 4 years, uncertainty remains, and extended follow-up of this and other cohorts is warranted... - Cardiovascular disease in kidney donors: matched cohort studyAmit X Garg
Division of Nephrology, Department of Medicine, University of Western Ontario, London, ON, Canada
BMJ 344:e1203. 2012..To determine whether people who donate a kidney have an increased risk of cardiovascular disease... - Seasonal variation of serum lipid levels in stable renal transplant recipientsBrian M Wong
Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Ont, Canada
Nephron Clin Pract 105:c126-31. 2007..We sought to determine whether seasonal differences exist in RTR, a group at high risk for hyperlipidemia... - Determinants of bone mineral density in stable kidney transplant recipientsAlok K Gupta
Division of Nephrology, University of Toronto, Toronto, Ontario, Canada
J Nephrol 25:373-83. 2012..Kidney transplant recipients (KTR) are at increased risk for bone loss. Determinants of bone mineral density (BMD) in an unselected KTR population have not previously been described... - Organ donation after cardiac death: donor and recipient outcomes after the first three years of the Ontario experienceRoberto Hernadez-Alejandro
Multi Organ Transplant Program, London Health Science Centre, London, ON, Canada
Can J Anaesth 58:599-605. 2011..The aim of this study was to explore donor and recipient outcomes from organ donation after cardiac death (DCD) in Ontario and to examine the impact of DCD on deceased donation rates in Ontario since its implementation... - The long-term quality of life of living kidney donors: a multicenter cohort studyK Clemens
Division of Nephrology, University of Western Ontario, London, Ontario, Canada
Am J Transplant 11:463-9. 2011..Our findings are reassuring for the practice of living transplantation. Those who donate a kidney in centers that use routine pretransplant donor evaluation have good long-term quality of life... - Discovering misattributed paternity in living kidney donation: prevalence, preference, and practiceAnn Young
Division of Nephrology, University of Western Ontario, London, ON, Canada
Transplantation 87:1429-35. 2009..Opinions on how to deal with this sensitive information are variable. Discussion among transplant professionals will facilitate best practices and policies. Strategies adopted by some centers can be considered... - Similar outcomes for Canadian renal transplant recipients followed up in transplant centers and satellite clinicsTammy M Keough-Ryan
Department of Medicine, Dalhousie University, Halifax, NS, Canada
Transplantation 90:591-6. 2010..The outcomes of RTRs followed up in SCs have not been formally compared with those followed up in transplant centers (TCs)... - The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapyDoreen M Rabi
Department of Medicine, University of Calgary, Calgary, Alberta, Canada
Can J Cardiol 27:415-433.e1-2. 2011..We also discussed the recent analyses that examined the association between angiotensin II receptor blockers (ARBs) and cancer... - Improvement of periodic limb movements following kidney transplantationJaime M Beecroft
Department of Medicine, University of Calgary, Calgary, Alta, Canada
Nephron Clin Pract 109:c133-9. 2008..We evaluated the effect of kidney transplantation on periodic limb movements in a group of patients with end-stage renal disease... - Meta-analysis: risk for hypertension in living kidney donorsNeil Boudville
University of Western Ontario, London, Ontario, Canada
Ann Intern Med 145:185-96. 2006..Future controlled, prospective studies with long periods of follow-up will better delineate safety and identify donors at lowest risk for long-term morbidity... - Paraoxonase 1 Phenotype and Mass in South Asian versus Caucasian Renal Transplant RecipientsPhilip W Connelly
Department of Medicine, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, ON, Canada M5B 1W8
J Lipids 2012:608580. 2012..The two-substrate method for determining PON1 phenotype may be of value for future studies of cardiovascular complications in renal transplant recipients... - Adiponectin in renal disease - a review of the evidence as a risk factor for cardiovascular and all-cause mortalityPhilip W Connelly
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Crit Rev Clin Lab Sci 49:218-31. 2012..We review here the basic science evidence and clinical studies of the role of renal function and kidney disease as a determinant of adiponectin... - Renal transplant outcome in high-cardiovascular risk recipientsTarun K Jeloka
Renal Transplant Programme, Toronto General Hospital, University of Toronto, Toronto, ON, Canada
Clin Transplant 21:609-14. 2007..Hence, we looked at the CV outcome in patients with known pre-transplant CAD...