Irfan A Dhalla
Affiliation: St. Michael's Hospital
- Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodoneIrfan A Dhalla
Department of Medicine, University of Toronto, and the Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario
CMAJ 181:891-6. 2009..Opioid-related mortality appears to be increasing in Canada. We examined the true extent of the problem and the impact of the introduction of long-acting oxycodone...
- Perspectives on the National Institute for Health and Clinical Excellence's recommendations to use health technologies only in researchIrfan A Dhalla
Medicine and Health Policy, Management and Evaluation, University of Toronto, Keenan Research Centre of Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario M5B 1W8, Canada
Int J Technol Assess Health Care 25:272-80. 2009..Nevertheless, these decisions are often controversial and implementation can be problematic...
- Potentially inappropriate prescribing in Canada relative to the USPaula A Rochon
Kunin Lunenfeld Applied Research Unit, Department of Medicine, University of Toronto, Baycrest Centre for Geriatric Care, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Drugs Aging 21:939-47. 2004..To explore the prescribing of potentially inappropriate drug therapy in Ontario, Canada where there is a restrictive drug formulary relative to the US where there is no single drug formulary...
- Potentially inappropriate prescribing in Ontario community-dwelling older adults and nursing home residentsChristopher J Lane
Department of Medicine, University of Toronto, Toronto, Canada
J Am Geriatr Soc 52:861-6. 2004..To compare patterns of potentially inappropriate drug therapy prescribing in community-dwelling older adults and nursing home residents in Ontario, Canada...
- Effect of a course-based intervention and effect of medical regulation on physicians' opioid prescribingMeldon Kahan
Department of Family and Community Medicine, University of Toronto U of T, Ontario, Canada
Can Fam Physician 59:e231-9. 2013..To examine the effects of an intensive 2-day course on physicians' prescribing of opioids...
- Opioid dose and risk of road trauma in Canada: a population-based studyTara Gomes
Institute for Clinical Evaluative Sciences, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
JAMA Intern Med 173:196-201. 2013..Use of opioids may predispose drivers to road trauma, yet the effect of opioid dose on this association is unknown...
- Clustering of opioid prescribing and opioid-related mortality among family physicians in OntarioIrfan A Dhalla
Department of Medicine, University of Toronto, Toronto, Ont
Can Fam Physician 57:e92-6. 2011..To examine whether variation in prescribing at the level of the individual physician is associated with opioid-related mortality...
- Are broad-spectrum fluoroquinolones more likely to cause Clostridium difficile-associated disease?Irfan A Dhalla
Department of Medicine, Unversity of Toronto, Ontario M4E 3E9, Canada
Antimicrob Agents Chemother 50:3216-9. 2006..difficile-associated disease requiring hospitalization among patients prescribed gatifloxacin or moxifloxacin compared to levofloxacin...
- Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort studyIrfan A Dhalla
St Michael s Hospital and Institute for Clinical Evaluative Sciences, Toronto, Ontario M5B 1W8, Canada
Ann Intern Med 158:447-55. 2013..Some evidence suggests that chlorthalidone may be superior to hydrochlorothiazide for the treatment of hypertension...
- Selective serotonin reuptake inhibitors and pulmonary arterial hypertension: a case-control studyIrfan A Dhalla
Department of Medicine, St Michael s Hospital, 30 Bond St, Toronto, ON, M5B 1W8, Canada
Chest 141:348-53. 2012..Animal and human studies suggest that selective serotonin reuptake inhibitors (SSRIs) might be useful for the prevention or treatment of pulmonary arterial hypertension...
- Opioid dose and drug-related mortality in patients with nonmalignant painTara Gomes
Institute for Clinical Evaluative Sciences, G Wing 106, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
Arch Intern Med 171:686-91. 2011..However, the risk-benefit ratio of high-dose opioid therapy is not well characterized. The objective of this study was to characterize the relationship between opioid dose and opioid-related mortality...
- Private expenditures on brand name prescription drugs after generic entryDahlia Y Balaban
Faculty of Medicine, University of Toronto, Toronto, ON, Canada
Appl Health Econ Health Policy 11:523-9. 2013..Generic drugs offer a less expensive and therapeutically equivalent alternative to brand name drugs. Nevertheless, many Canadian private drug plans continue to pay for brand name drugs even after generics become available...
- Creating the right evidence for system changeKenneth Lam
Kenneth Lam, Bsc, is a Keenan research summer student at the Li Ka Shing Knowledge Institute, St Michael s Hospital, in Toronto, Ontario and a medical student at Western University, in London, Ontario
Healthc Q 16:22-6. 2013..They then describe what must be done to make similar trials a regular tool of healthcare policy. ..
- Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithmAndrea Gruneir
Women s College Research Institute, University of Toronto, Canada
Open Med 5:e104-11. 2011..The purpose of this study was to describe medical patients identified using a recently published and validated algorithm (the LACE index) as being at high risk for readmission and to examine their actual hospital readmission rates...
- Comparative effectiveness research in Ontario, Canada: producing relevant and timely information for health care decision makersDanielle M Whicher
Center for Medical Technology Policy, University of Toronto, Canada
Milbank Q 87:585-606. 2009..As the United States begins to invest in comparative effectiveness, it would be wise to look at other functioning research networks to understand the infrastructure and funding required to support them...
- Oral vitamin B12 therapy in the primary care setting: a qualitative and quantitative study of patient perspectivesJeff C Kwong
Department of Family and Community Medicine, University of Toronto, 263 McCaul Street, Toronto, Ontario, M5T 1W7, Canada
BMC Fam Pract 6:8. 2005..We investigated patient perspectives on switching from injection to oral B12 therapy...
- Primary medication non-adherence after discharge from a general internal medicine serviceBrooks A Fallis
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
PLoS ONE 8:e61735. 2013....
- Dependence and addiction during chronic opioid therapyDavid N Juurlink
Sunnybrook Research Institute, Toronto, Canada
J Med Toxicol 8:393-9. 2012....
- Risks and benefits of importing prescription medications from lower-income countriesIrfan A Dhalla
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
JAMA 300:1453-5. 2008
- A comparison of Canadian medical students from rural and non-rural backgroundsJeff C Kwong
Community Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada
Can J Rural Med 10:36-42. 2005..Very little is known about medical students from rural areas currently enrolled in Canadian medical schools...
- Inappropriate prescribing before and after nursing home admissionIrfan A Dhalla
Faculty of Medicine, University of Toronto, 2113 40 Gerrard Street East, Toronto, Ontario M5B 2E8, Canada
J Am Geriatr Soc 50:995-1000. 2002..To compare the prevalence of inappropriate prescribing before and after nursing home admission and to determine which patient and physician characteristics are associated with inappropriate prescribing in the nursing home setting...