Karen Ea Burns

Summary

Affiliation: St. Michael's Hospital
Country: Canada

Publications

  1. ncbi Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
  2. ncbi A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine and Departments of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Trials 12:70. 2011
  3. ncbi Catheter-related right atrial thrombus and pulmonary embolism: a case report and systematic review of the literature
    Karen E A Burns
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada
    Can Respir J 16:163-5. 2009
  4. ncbi Wean Earlier and Automatically with New technology (the WEAN study): a protocol of a multicentre, pilot randomized controlled trial
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Trials 10:81. 2009
  5. ncbi Weaning critically ill adults from invasive mechanical ventilation: a national survey
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada
    Can J Anaesth 56:567-76. 2009
  6. ncbi Use of non-invasive ventilation to wean critically ill adults off invasive ventilation: meta-analysis and systematic review
    Karen E A Burns
    Interdepartmental Division of Critical Care, St Michael s Hospital, Toronto, ON, Canada M5B 1W8
    BMJ 338:b1574. 2009
  7. ncbi A critical review of thromboembolic complications associated with central venous catheters
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
    Can J Anaesth 55:532-41. 2008
  8. ncbi Automating the weaning process with advanced closed-loop systems
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada
    Intensive Care Med 34:1757-65. 2008
  9. ncbi A meta-analysis of noninvasive weaning to facilitate liberation from mechanical ventilation
    Karen E A Burns
    Division of Critical Care Medicine, London Health Sciences Centre Victoria Hospital
    Can J Anaesth 53:305-15. 2006
  10. ncbi Bilevel noninvasive positive pressure ventilation for acute respiratory failure: survey of Ontario practice
    Karen E A Burns
    Division of Critical Care Medicine, University of Western Ontario, London, Ontario, Canada
    Crit Care Med 33:1477-83. 2005

Detail Information

Publications17

  1. ncbi Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
    ..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
  2. ncbi A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine and Departments of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Trials 12:70. 2011
    ....
  3. ncbi Catheter-related right atrial thrombus and pulmonary embolism: a case report and systematic review of the literature
    Karen E A Burns
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada
    Can Respir J 16:163-5. 2009
    ..It also underscores the important role of transesophageal echocardiography and thrombolysis in the diagnosis and management, respectively, of right heart thromboemboli with associated pulmonary embolism...
  4. ncbi Wean Earlier and Automatically with New technology (the WEAN study): a protocol of a multicentre, pilot randomized controlled trial
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Trials 10:81. 2009
    ..Automated Weaning holds promise as a strategy to reduce the time spent on the ventilator, decrease ICU length of stay, and improve clinically important outcomes...
  5. ncbi Weaning critically ill adults from invasive mechanical ventilation: a national survey
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada
    Can J Anaesth 56:567-76. 2009
    ..To determine the stated practices of clinicians in weaning critically ill adults from invasive ventilation...
  6. ncbi Use of non-invasive ventilation to wean critically ill adults off invasive ventilation: meta-analysis and systematic review
    Karen E A Burns
    Interdepartmental Division of Critical Care, St Michael s Hospital, Toronto, ON, Canada M5B 1W8
    BMJ 338:b1574. 2009
    ..To summarise the evidence for early extubation with immediate application of non-invasive ventilation compared with continued invasive weaning on important outcomes in intubated adults with respiratory failure...
  7. ncbi A critical review of thromboembolic complications associated with central venous catheters
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
    Can J Anaesth 55:532-41. 2008
    ..However, important patient, clot, and institutional considerations mandate that treatment for patients with RHTE and PE be individualized...
  8. ncbi Automating the weaning process with advanced closed-loop systems
    Karen E A Burns
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada
    Intensive Care Med 34:1757-65. 2008
    ....
  9. ncbi A meta-analysis of noninvasive weaning to facilitate liberation from mechanical ventilation
    Karen E A Burns
    Division of Critical Care Medicine, London Health Sciences Centre Victoria Hospital
    Can J Anaesth 53:305-15. 2006
    ....
  10. ncbi Bilevel noninvasive positive pressure ventilation for acute respiratory failure: survey of Ontario practice
    Karen E A Burns
    Division of Critical Care Medicine, University of Western Ontario, London, Ontario, Canada
    Crit Care Med 33:1477-83. 2005
    ..Some factors associated with variation in NIV use may be suitable targets for utilization improvement interventions...
  11. ncbi Pharmacologic treatments for acute respiratory distress syndrome and acute lung injury: systematic review and meta-analysis
    Neill Adhikari
    Department of Critical Care Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Treat Respir Med 3:307-28. 2004
    ..Our objective was to systematically evaluate this literature to determine the effects of these interventions on important clinical outcomes...
  12. ncbi Noninvasive ventilation for acute respiratory failure near the end of life
    Tasnim Sinuff
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 36:789-94. 2008
    ....
  13. ncbi Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis
    Neill K J Adhikari
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
    BMJ 334:779. 2007
    ....
  14. ncbi The design and interpretation of pilot trials in clinical research in critical care
    Donald M Arnold
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Crit Care Med 37:S69-74. 2009
    ..The objective of this review is to highlight the importance of randomized pilot trials and to describe key features of their design and interpretation using examples from critical care...
  15. ncbi Randomized trials stopped early for benefit: a systematic review
    Victor M Montori
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 294:2203-9. 2005
    ..These findings suggest clinicians should view the results of such trials with skepticism...
  16. ncbi Abstract reporting in randomized clinical trials of acute lung injury: an audit and assessment of a quality of reporting score
    Karen E A Burns
    Graduate Program in Health Research Methodology, McMaster University, Hamilton, Ontario, Canada
    Crit Care Med 33:1937-45. 2005
    ..Checklists may aid authors and editors in prioritizing important criteria for inclusion in RCT abstracts...
  17. ncbi Pulmonary embolism on postmortem examination: an under-recognized complication in lung-transplant recipients?
    Karen E A Burns
    Division of Critical Care Medicine, London Health Sciences Center Victoria Hospital, London, Ontario, Canada
    Transplantation 77:692-8. 2004
    ..Postmortem reports highlight the importance of factors that individually or collectively limit survival. The prevalence of pulmonary embolism (PE) at autopsy in lung-transplant recipients has not been characterized previously...