Research Topics
| Nancy N BaxterSummaryAffiliation: St. Michael's Hospital Country: Canada Publications
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Detail Information
Publications
A population-based study of rates of childbirth in recurrence-free female young adult survivors of non-gynecologic malignanciesNancy N Baxter
Department of Surgery and Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, 30 Bond Street 16CC 40, Toronto, ON M5B 1W8, Canada
BMC Cancer 13:30. 2013..Fertility is an important issue for long-term survivors of malignancies developing during reproductive years. We designed a population-based study to investigate childbirth in female young adult survivors of non-gynecologic malignancies...
Association between colonoscopy and colorectal cancer mortality in a US cohort according to site of cancer and colonoscopist specialtyNancy N Baxter
Keenan ResearchCentre, Li Ka Shing Knowledge Institute, andDivision of General Surgery, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
J Clin Oncol 30:2664-9. 2012..We designed this study to evaluate the association of colonoscopy with colorectal cancer (CRC) death in the United States by site of CRC and endoscopist specialty...
Risk of pelvic fractures in older women following pelvic irradiationNancy N Baxter
Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, Minneapolis 55455, USA
JAMA 294:2587-93. 2005..Pelvic fractures, including hip fractures, are a major source of morbidity and mortality in older women. Although therapeutic pelvic irradiation could increase the risk of such fractures, this effect has not been studied...
Analysis of administrative data finds endoscopist quality measures associated with postcolonoscopy colorectal cancerNancy N Baxter
Department of Surgery and Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Gastroenterology 140:65-72. 2011..We investigated whether characteristics of endoscopists, determined from administrative data, are associated with development of postcolonoscopy colorectal cancer (PCCRC)...
Equal for whom? Addressing disparities in the Canadian medical system must become a national priorityNancy N Baxter
Department of Surgery and Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, and University of Toronto, Toronto, Ont
CMAJ 177:1522-3. 2007
Is lymph node count an ideal quality indicator for cancer care?Nancy N Baxter
Department of Surgery and the Keenan Research Centre at the Li Ka Shing Knowledge Institute St Michael s Hospital, Toronto, Ontario, Canada
J Surg Oncol 99:265-8. 2009..This article discusses potential pitfalls in the use of lymph node count as a quality indicator...
Risk of dementia in older breast cancer survivors: a population-based cohort study of the association with adjuvant chemotherapyNancy N Baxter
Department of Surgery, St Michaels Hospital, Toronto, Canada
J Am Geriatr Soc 57:403-11. 2009..To assess whether there is an association between delivery of adjuvant chemotherapy to older women with breast cancer and development of dementia over time...
Reliability and validity of the body image after breast cancer questionnaireNancy N Baxter
Department of Surgery, University of Toronto, Canada
Breast J 12:221-32. 2006..The BIBCQ provides a reliable and valid assessment of the long-term impact of breast cancer on body image. It is suitable for use in research focusing on this issue...
An evaluation of the relationship between lymph node number and staging in pT3 colon cancer using population-based dataNancy N Baxter
Department of Surgery and Keenan Research Centre in the Li Ka Shing Knowledge Institute of St Michael s Hospital, University of Toronto, Ontario, Canada
Dis Colon Rectum 53:65-70. 2010..The number of lymph nodes examined has been proposed as a quality benchmark for colon cancer surgery, although it is unknown whether this strategy reduces understaging...
Association of colonoscopy and death from colorectal cancerNancy N Baxter
Li Ka Shing Knowledge Institute, St Michael s Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
Ann Intern Med 150:1-8. 2009..Colonoscopy is advocated for screening and prevention of colorectal cancer (CRC), but randomized trials supporting the benefit of this practice are not available...
Postoperative irradiation for rectal cancer increases the risk of small bowel obstruction after surgeryNancy N Baxter
Department of Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Ann Surg 245:553-9. 2007..To determine the risk of small bowel obstruction (SBO) after irradiation (RT) for rectal cancer..
Organ preservation for rectal cancerNancy N Baxter
Department of Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
J Clin Oncol 25:1014-20. 2007..The use of adjuvant therapy with local excision, particularly in patients with T2 lesions, has promise but should be considered only as part of a clinical trial...
Stage-specific effect of adjuvant therapy following gastric cancer resection: a population-based analysis of 4,041 patientsNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Ann Surg Oncol 15:500-7. 2008..Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population...
Multistate models for comparing trends in hospitalizations among young adult survivors of colorectal cancer and matched controlsRinku Sutradhar
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
BMC Health Serv Res 12:353. 2012..A large percentage of these patients live at least 5 years after diagnosis, but it is unknown whether their rate of hospitalizations after this 5-year mark is comparable to the general population...
Racial disparities in rectal cancer treatment: a population-based analysisArden M Morris
Department of Surgery, Section of Colon and Rectal Surgery, University of Minnesota, Minneapolis, USA
Arch Surg 139:151-5; discussion 156. 2004....
Lymph node evaluation in colorectal cancer patients: a population-based studyNancy N Baxter
Division of Surgical Oncology, Department of Surgery, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA
J Natl Cancer Inst 97:219-25. 2005..We used data from the National Cancer Institute's Surveillance, Epidemiology, and End Results program to determine the proportion of colorectal cancer patients in the United States who receive adequate lymph node evaluation...
The status of radical proctectomy and sphincter-sparing surgery in the United StatesRocco Ricciardi
Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, USA
Dis Colon Rectum 50:1119-27; discussion 1126-7. 2007..The rate of sphincter-sparing surgery with reestablishment of intestinal continuity in the general population of the United Stares is unknown...
Population-based analyses of lymph node metastases in colorectal cancerRocco Ricciardi
Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA, and St. Michael's Hospital, University of Toronto, Ontario, Canada
Clin Gastroenterol Hepatol 4:1522-7. 2006..This risk should be considered when balancing the risks and benefits of minimally invasive techniques such as local excision or endoscopic resection for the treatment of CRC...
Effect of colonoscopy on colorectal cancer incidence and mortality: an instrumental variable analysisBinu J Jacob
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Gastrointest Endosc 76:355-64.e1. 2012..Using population-based health services information to estimate the effectiveness of colonoscopy on colorectal cancer (CRC) outcomes is prone to selection bias...
Feasibility and safety of adhesiolysis using transgastric NOTES approach: a pilot survival study in a porcine modelElena Dubcenco
St Michael s Hospital, Toronto, Ontario, Canada
Surg Innov 18:106-13. 2011..The aim of the study was to evaluate the feasibility and safety of adhesiolysis by using a novel transgastric NOTES approach and collect pilot data on adhesion recurrence after transgastric NOTES adhesiolysis...
Variations in surgical treatment and outcomes of patients with pancreatic cancer: a population-based studyAnand Govindarajan
Division of General Surgery, University of Toronto, Toronto, Canada
Ann Surg Oncol 15:175-85. 2008..There is ongoing debate on how variations in surgical technique affect outcomes in pancreatic cancer. This population-based study examines current surgical practice and outcomes for cancer of the pancreatic head...
Video. "No scar" small bowel resection in a survival porcine model using transcolonic NOTES(®) and transabdominal approachElena Dubcenco
Division of Gastroenterology, St Michael s Hospital, Toronto, ON, Canada
Surg Endosc 25:930-4. 2011..Our study was designed to evaluate the feasibility of performing small bowel resection by transcolonic NOTES(®) and transabdominal approach using rigid laparoscopic and flexible endoscopic instruments...
Long-term survival in young adults with colorectal cancer: a population-based studyShawn S Forbes
Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Dis Colon Rectum 53:973-8. 2010..This study compares the long-term survival of young adults with colorectal cancer who lived a minimum of 5 years after diagnosis with a cancer-free control population...
Managed care enrollment and chronically disabled women with breast cancerElizabeth B Habermann
Division of Health Policy and Management, School of Public Health, University of Minnesota, 420 Delaware St SE, MMC 729, Minneapolis, MN 55455, USA
Am J Manag Care 14:514-20. 2008..To assess whether managed care enrollment or healthcare utilization level among women enrolled in Medicare because of disability affects stage at diagnosis and treatment of breast cancer...
Impact of preoperative radiation for rectal cancer on subsequent lymph node evaluation: a population-based analysisNancy N Baxter
Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
Int J Radiat Oncol Biol Phys 61:426-31. 2005..To determine the impact of preoperative radiotherapy (RT) on the accuracy of lymph node staging (LNS). Preoperative RT is a well-established component of rectal cancer treatment but its impact on LNS is unknown...
Increased risk of rectal cancer after prostate radiation: a population-based studyNancy N Baxter
Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
Gastroenterology 128:819-24. 2005..Radiation therapy for prostate cancer has been associated with an increased rate of pelvic malignancies, particularly bladder cancer. The association between radiation therapy and colorectal cancer has not been established...
Increasing negative lymph node count is independently associated with improved long-term survival in stage IIIB and IIIC colon cancerPaul M Johnson
Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
J Clin Oncol 24:3570-5. 2006..CONCLUSION: The number of negative nodes is an important independent prognostic factor for patients with stage IIIB and IIIC colon cancer...
Crohn's colitis: the incidence of dysplasia and adenocarcinoma in surgical patientsJustin A Maykel
Department of Surgery, Section of Colon and Rectal Surgery, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, USA
Dis Colon Rectum 49:950-7. 2006....
Adjuvant therapy for resected gastric cancer--rapid, yet incomplete adoption following results of intergroup 0116 trialNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 70:1073-80. 2008..This study examined the adoption of adjuvant treatment following the trial results and the factors associated with its use...
Surgical management of intrahepatic cholangiocarcinoma--a population-based studyJensen C C Tan
Department of Surgery, Division of General Surgery, University of Toronto, Toronto, Canada
Ann Surg Oncol 15:600-8. 2008..Cholangiocarcinoma (CCA) is associated with poor survival and therapeutic nihilism. To date, there has not been an examination of the surgical management of CCA at a population level...
Trends in the treatment of ductal carcinoma in situ of the breastNancy N Baxter
Division of Surgical Oncology and School of Public Health, University of Minnesota, Minneapolis 55455, USA
J Natl Cancer Inst 96:443-8. 2004..This study was designed to evaluate the use of surgery and radiation therapy in treating DCIS...
Are we overtreating some patients with rectal cancer?David A Rothenberger
Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA
Oncology (Williston Park) 18:1789-96; discussion 1796, 1799-804. 2004..Development of new clinical trials to determine whether current practice guidelines are promoting overtreatment of selected rectal cancer patients is proposed...
Inadequacy of lymph node staging in gastric cancer patients: a population-based studyNancy N Baxter
Department of Surgery, Division of Surgical Oncology, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Ann Surg Oncol 12:981-7. 2005..e., had the recommended minimum of 15 nodes examined for gastric cancer staging. Better results at one registry (Hawaii) indicate that substantial improvements could be made...
Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failureKelli M Bullard
Department of Surgery, Division of Colon and Rectal Surgery, University of Minnesota, Minneapolis, Minnesota, USA
Dis Colon Rectum 48:438-43. 2005..Despite its efficacy, preoperative radiation therapy may inhibit healing and contribute to wound complications. This study was designed to evaluate perineal wound complications after abdominoperineal resection...
Trends in the incidence of invasive and in situ vulvar carcinomaPatricia L Judson
Department of Obstetrics, Gynecology and Women s Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Obstet Gynecol 107:1018-22. 2006..To characterize the incidence of vulvar carcinoma in situ and vulvar cancer over time...
Colon and rectal complications after heart and lung transplantationHilary J Goldberg
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, University of Minnesota, Minneapolis, USA
J Am Coll Surg 202:55-61. 2006..These complications occur more frequently in patients who undergo lung and heart-lung transplantation as compared with heart transplantation alone...
Increasing prevalence and severity of Clostridium difficile colitis in hospitalized patients in the United StatesRocco Ricciardi
Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, USA
Arch Surg 142:624-31; discussion 631. 2007....
Lymph node evaluation in early-stage colon cancerAnand Govindarajan
Division of General Surgery, Keenan Research Centre at the Li Ka Shing Knowledge Institute St Michael s Hospital, Toronto, Ontario, Canada
Clin Colorectal Cancer 7:240-6. 2008..Also, it might not improve colon cancer staging above standard pathology, and should be restricted to use in research settings...
Social disparities in the use of colonoscopy by primary care physicians in OntarioBinu J Jacob
Clinical Decision Making and Health Care, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario M5G2C4, Canada
BMC Gastroenterol 11:102. 2011..This research was designed to describe long-term trends in the use of colonoscopy by primary care physicians (PCPs) in Ontario, and to determine whether PCP characteristics influence the use of colonoscopy...
The utility of pudendal nerve terminal motor latencies in idiopathic incontinenceRocco Ricciardi
Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
Dis Colon Rectum 49:852-7. 2006..Bilaterally but not unilaterally prolonged pudendal nerve terminal motor latency is associated with poorer function and physiology in the incontinent patient with an intact sphincter...
Practice patterns for the management of hepatic metastases from colorectal cancer: a mixed methods analysisAlice C Wei
Division of General Surgery, University Health Network, University of Toronto, Toronto, ON, Canada
Ann Surg Oncol 20:1567-74. 2013..We sought to characterize the gap between current practice and best evidence for the management of these patients and to identify barriers that hamper effective utilization of metastasectomy...
Sociodemographics and comorbidities influence decisions to undergo pancreatic resection for neoplastic lesionsCharbel Sandroussi
Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, ON, Canada
J Gastrointest Surg 14:1401-8. 2010..The aim of this study was to determine the factors contributing to the decision not to operate for resectable pancreatic neoplasms...
Endorectal ultrasound-directed biopsy: a useful technique to detect local recurrence of rectal cancerJeffrey J Morken
Division of Colon and Rectal Surgery, University of Minnesota, Minneapolis, USA
Int J Colorectal Dis 21:258-64. 2006..It may be particularly useful in patients at higher risk for local recurrence (i.e., after endocavitary radiation and local excision) and may allow early detection of local recurrence, thereby permitting attempts at curative resection...
Do patients consider preoperative chemoradiation for primary rectal cancer worthwhile?Erin D Kennedy
Division of General Surgery, Toronto General Hospital and Toronto General Research Institute, Toronto, Ontario, Canada
Cancer 117:2853-62. 2011..The objective of this study was to elicit future patients' preferences for preoperative chemoradiation (pre-CRT) for rectal cancer to determine whether patients' preferences are consistent with current treatment guidelines...
Retroperitoneal sarcoma: a population-based analysis of epidemiology, surgery, and radiotherapyGeoffrey A Porter
Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
Cancer 106:1610-6. 2006..The objective of this study was to examine the incidence and treatment of RPS, specifically regarding the use of adjuvant radiotherapy...
Trends in the treatment and outcome of pancreatic cancer in the United StatesNancy N Baxter
Division of General Surgery, St Michael s Hospital, University of Toronto, Toronto, Canada
Ann Surg Oncol 14:1320-6. 2007..Although pancreatic cancer is the fourth leading cause of cancer death, few studies have evaluated population-based trends in diagnosis, management, and outcome...
Is the increasing rate of local excision for stage I rectal cancer in the United States justified?: a nationwide cohort study from the National Cancer DatabaseY Nancy You
Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Ann Surg 245:726-33. 2007..Determine rates of local excision (LE) over time, and test the hypothesis that LE carries increased oncologic risks but reduced perioperative morbidity when compared with standard resection (SR)...
Anal resting pressures at manometry correlate with the Fecal Incontinence Severity Index and with presence of sphincter defects on ultrasoundLiliana Bordeianou
Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Dis Colon Rectum 51:1010-4. 2008..We describe the relationship between anorectal manometry, fecal incontinence severity, and findings at endoanal ultrasound...
Association of hospital spending intensity with mortality and readmission rates in Ontario hospitalsTherese A Stukel
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
JAMA 307:1037-45. 2012..The extent to which better spending produces higher-quality care and better patient outcomes in a universal health care system with selective access to medical technology is unknown...
The development of a novel intracolonic occlusion balloon for transcolonic natural orifice transluminal endoscopic surgery: description of the technique and early experience in a porcine model (with videos)Elena Dubcenco
Division of Gastroenterology, University of Toronto, St Michael s Hospital, Toronto, Ontario, Canada
Gastrointest Endosc 68:760-6. 2008..Transgastric and transvaginal approaches in natural orifice transluminal endoscopic surgery (NOTES) are the most commonly used, although the transcolonic approach may have some advantages...
Does it matter what a hospital is "high volume" for? Specificity of hospital volume-outcome associations for surgical procedures: analysis of administrative dataDavid R Urbach
Department of Surgery, University of Toronto, 200 Elizabeth Street, 9EN 236A, Toronto, ON M5G 2C4, Canada
BMJ 328:737-40. 2004..To determine whether the improved outcome of a surgical procedure in high volume hospitals is specific to the volume of the same procedure...
Patient decision aids for cancer treatment: are there any alternatives?Gillian Spiegle
University of Toronto, Ontario, Canada
Cancer 119:189-200. 2013..The objectives of this study were to perform a systematic review to identify alternate types of decision support interventions (DSIs) for cancer treatment and a meta-analysis to compare the effectiveness of these DSIs to pDAs...
Developing a research agenda for the American Society of Colon and Rectal Surgeons: results of a delphi approachCaroline G Burt
Department of Surgery and Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Canada
Dis Colon Rectum 52:898-905. 2009..By use of a systematic approach, the aim of this project was to survey a group of colorectal specialists and reach a consensus on the research questions of highest importance in terms of clinical care...
Measuring fecal incontinenceNancy N Baxter
Division of Colorectal Surgery, University of Minnesota, Minneapolis, MN, USA
Dis Colon Rectum 46:1591-605. 2003..The strengths and weaknesses of currently available measures are presented in this review...
Outcomes after open versus laparoscopic gastric bypassRocco Ricciardi
Department of Surgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Surg Laparosc Endosc Percutan Tech 16:317-20. 2006..001). In conclusion, LGB is associated with significantly lower mean hospital stay and with reduced morbidity and mortality as compared with OGB...
The management of patients with T1 adenocarcinoma of the low rectum: a decision analysisCalvin F Johnston
Department of Clinical Decision Making and Health Care, University Health Network and Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Dis Colon Rectum 56:400-7. 2013..Decision making for patients with T1 adenocarcinoma of the low rectum, when treatment options are limited to a transanal local excision or abdominoperineal resection, is challenging...
A stoma quality of life scaleNancy N Baxter
Department of Surgery, University of Minnesota, Minneapolis, and Department of Biostatistics, Mayo Clinic Cancer Center Statistics, Rochester, Minnesota, USA
Dis Colon Rectum 49:205-12. 2006..CONCLUSIONS: The Stoma Quality of Life Scale demonstrates reasonable psychometric properties for measuring quality of life in patients with stomas. Further studies are needed to refine the instrument...
Surgical therapy for anorectal melanomaKelli M Bullard
Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
J Am Coll Surg 196:206-11. 2003..Local resection does not increase the risk of local or regional recurrence. APR offers no survival advantage over local excision. We advocate wide local excision as primary therapy for anorectal melanoma when technically feasible...
The impact of a change in Medicare reimbursement policy and HEDIS measures on stage at diagnosis among Medicare HMO and fee-for-service female breast cancer patientsElizabeth B Habermann
Division of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, MN 55455, USA
Med Care 45:761-6. 2007....
Long-term results of anterior sphincteroplastyAlberto Bravo Gutierrez
Canary University Hospital, La Laguna University, Canary Islands, Spain
Dis Colon Rectum 47:727-31; discussion 731-2. 2004..Incontinence at ten years had a negative effect on quality of life. Further research is needed to develop techniques to improve long-term continence in these patients...
