Marc J Servant

Summary

Country: Canada

Publications

  1. Khan K, Dô F, Marineau A, Doyon P, Clément J, Woodgett J, et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol Cell Biol. 2015;35:3029-43 pubmed publisher
    ..This study identifies the role of a GSK-3/β-catenin axis in antiviral innate immunity. ..
  2. Clément J, Bibeau Poirier A, Gravel S, Grandvaux N, Bonneil E, Thibault P, et al. Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association. J Virol. 2008;82:3984-96 pubmed publisher
    ..Importantly, our study establishes a molecular link between the role of serine 339 in IRF-3 homodimerization, CBP association, and its destabilization. ..