Frederic Series

Summary

Country: Canada

Publications

  1. doi request reprint Can improving sleep influence sleep-disordered breathing?
    Frederic Series
    Centre de Pneumologie Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, Canada
    Drugs 69:77-91. 2009
  2. ncbi request reprint Effects of protriptyline on snoring characteristics
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Chest 104:14-8. 1993
  3. ncbi request reprint Site of phrenic nerve stimulation-induced upper airway collapse: influence of expiratory time
    F Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Sainte Foy, Quebec, Canada G1V 4G5
    J Appl Physiol (1985) 92:665-71. 2002
  4. ncbi request reprint [Health-related quality of life measurement: a critical reading guide]
    Y Lacasse
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Rev Mal Respir 20:580-8. 2003
  5. pmc A new standardised and self-administered quality of life questionnaire specific to obstructive sleep apnoea
    Y Lacasse
    Centre de Recherche, Centre de Pneumologie, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Thorax 59:494-9. 2004
  6. ncbi request reprint Accuracy of an unattended home CPAP titration in the treatment of obstructive sleep apnea
    F Series
    Unite de Recherche, Centre de Pneumologie, Hôpital et Université Laval, Quebec, Canada
    Am J Respir Crit Care Med 162:94-7. 2000
  7. ncbi request reprint Assessment of upper airway dynamics in awake patients with sleep apnea using phrenic nerve stimulation
    F Series
    Centre de Recherche de l Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Am J Respir Crit Care Med 162:795-800. 2000
  8. ncbi request reprint Influence of genioglossus tonic activity on upper airway dynamics assessed by phrenic nerve stimulation
    F Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada G1V 4G5
    J Appl Physiol (1985) 92:418-23. 2002
  9. pmc Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study
    Frederic Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec City, Quebec, Canada
    Respir Res 10:74. 2009
  10. ncbi request reprint Prospective evaluation of nocturnal oximetry for detection of sleep-related breathing disturbances in patients with chronic heart failure
    Frederic Series
    Centre de Pneumologie Hôpital Laval, 2725, Chemin Sainte Foy, Sainte Foy, PQ, Canada G1V 4G5
    Chest 127:1507-14. 2005

Detail Information

Publications64

  1. doi request reprint Can improving sleep influence sleep-disordered breathing?
    Frederic Series
    Centre de Pneumologie Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, Canada
    Drugs 69:77-91. 2009
    ....
  2. ncbi request reprint Effects of protriptyline on snoring characteristics
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Chest 104:14-8. 1993
    ..We conclude that protriptyline can improve both snoring frequency and loudness in some nonapneic snorers, and that this improvement occurs mostly in the sleep stages where snoring is worst...
  3. ncbi request reprint Site of phrenic nerve stimulation-induced upper airway collapse: influence of expiratory time
    F Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Sainte Foy, Quebec, Canada G1V 4G5
    J Appl Physiol (1985) 92:665-71. 2002
    ..We conclude that twitch-induced UA collapse predominantly occurs at the pharyngeal level and that UA stability assessed by EPNS depends on the expiratory time at which twitches are performed...
  4. ncbi request reprint [Health-related quality of life measurement: a critical reading guide]
    Y Lacasse
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Rev Mal Respir 20:580-8. 2003
    ..Quality of life is rarely assessed in the pulmonary function laboratory. Quality of life, or at least some of its domains, should be directly measured...
  5. pmc A new standardised and self-administered quality of life questionnaire specific to obstructive sleep apnoea
    Y Lacasse
    Centre de Recherche, Centre de Pneumologie, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Thorax 59:494-9. 2004
    ..A study was therefore undertaken to validate a new OSA specific self-administered questionnaire (the Quebec Sleep Questionnaire, QSQ) for use in clinical trials...
  6. ncbi request reprint Accuracy of an unattended home CPAP titration in the treatment of obstructive sleep apnea
    F Series
    Unite de Recherche, Centre de Pneumologie, Hôpital et Université Laval, Quebec, Canada
    Am J Respir Crit Care Med 162:94-7. 2000
    ..1 +/- 1.7 h/ night) after 6.5 +/- 2.8 mo of CPAP treatment. These results indicate that auto-CPAP therapy represents a new useful and accurate way to identify conventional CPAP setting outside hospital and sleep laboratories...
  7. ncbi request reprint Assessment of upper airway dynamics in awake patients with sleep apnea using phrenic nerve stimulation
    F Series
    Centre de Recherche de l Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Am J Respir Crit Care Med 162:795-800. 2000
    ..We conclude that (1) BAMPS is potentially a useful tool to evaluate the dynamics of flow through the passive UA in awake OSAHS patients, (2) BAMPS may be superior to CMS in evaluating UA properties in OSAHS...
  8. ncbi request reprint Influence of genioglossus tonic activity on upper airway dynamics assessed by phrenic nerve stimulation
    F Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada G1V 4G5
    J Appl Physiol (1985) 92:418-23. 2002
    ..UA stability assessed by EPNS is dramatically modified during CO(2) ventilatory stimulation. Changes in tonic genioglossus EMG activity significantly contribute to the improvement in UA stability...
  9. pmc Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study
    Frederic Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec City, Quebec, Canada
    Respir Res 10:74. 2009
    ....
  10. ncbi request reprint Prospective evaluation of nocturnal oximetry for detection of sleep-related breathing disturbances in patients with chronic heart failure
    Frederic Series
    Centre de Pneumologie Hôpital Laval, 2725, Chemin Sainte Foy, Sainte Foy, PQ, Canada G1V 4G5
    Chest 127:1507-14. 2005
    ....
  11. ncbi request reprint Upper airway muscles awake and asleep
    Frederic Series
    Unite de Recherche, Centre de Pneumologie, Hôpital et Université Laval, 2725 Chemin Sainte Foy, Canada
    Sleep Med Rev 6:229-42. 2002
    ..Such integration will better inform understanding of the role of pharyngeal UA muscles in the pathophysiology of the sleep apnea/hypopnea syndrome...
  12. ncbi request reprint Assessment of upper airway stabilizing forces with the use of phrenic nerve stimulation in conscious humans
    Frederic Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada G1V 4G5
    J Appl Physiol (1985) 94:2289-95. 2003
    ....
  13. ncbi request reprint Influence of weight and sleep apnea status on immunologic and structural features of the uvula
    Frederic Series
    Unité de Recherche en Pneumologie, Centre de Recherce de l Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Quebec, Canada
    Am J Respir Crit Care Med 170:1114-9. 2004
    ....
  14. pmc Reliability of home CPAP titration with different automatic CPAP devices
    Frederic Series
    Unité de Recherche en Pneumologie, Centre de Recherche de l Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec City, Canada
    Respir Res 9:56. 2008
    ..Our objective was to compare pressure behaviour and effective pressure recommendations between three Automatic CPAP machines (Autoset Spirit, Remstar Auto, GK 420)...
  15. doi request reprint Concomitant responses of upper airway stabilizing muscles to transcranial magnetic stimulation in normal men
    Frederic Series
    Centre de Pneumologie Hôpital Laval, 2725 Chemin Sainte Foy, Sainte Foy, Quebec, Canada
    Exp Physiol 93:496-502. 2008
    ..We conclude that transcranial magnetic stimulation applied in the genioglossus area induces a concomitant motor response of upper airway stabilizing muscles with consistent changes in their motor responses during inspiratory manoeuvres...
  16. pmc Impediment in upper airway stabilizing forces assessed by phrenic nerve stimulation in sleep apnea patients
    F Series
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Universite Laval, Quebec City, Quebec, Canada
    Respir Res 6:99. 2005
    ..Phrenic nerve stimulation applied during wakefulness is a unique tool to assess Upper airway dynamic properties and to measure the overall mechanical effects of the inspiratory process on UA stability...
  17. ncbi request reprint [From oximetry to polysomnography: what should be used to diagnose sleep apnea syndrome?]
    F Series
    Institut Universitaire de Cardiologie et de Pneumologie, Hopital Laval, Sainte Foy, Quebec
    Rev Mal Respir 23:7S20-7S23. 2006
  18. ncbi request reprint Is treatment of obstructive sleep apnea syndrome with auto-CPAP useful?
    F Series
    Department of Medicine, Laval University, Chief sleep laboratory, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval
    Sleep 23:S161-5. 2000
    ..Some results suggest that automatic CPAP therapy may improve compliance to CPAP therapy. There is a need to better define if automatic CPAP therapy may benefit to specific groups of sleep apnea patients...
  19. ncbi request reprint Muscle fiber area distribution of musculus uvulae in obstructive sleep apnea and non-apneic snorers
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Int J Obes Relat Metab Disord 24:410-5. 2000
    ..To determine whether differences exist in the morphology of upper airway muscles between apneic and non-apneic snorers..
  20. ncbi request reprint Inspiratory flow dynamics during phrenic nerve stimulation in awake normals during nasal breathing
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Am J Respir Crit Care Med 160:614-20. 1999
    ..End-expiratory stimulations applied during exclusive nasal breathing induced 200 to 300 ms twitch inspiratory flow. The average maximal twitch flow of flow-limited twitches was higher during CMS than ES (1.18 +/- 0.29 L...
  21. ncbi request reprint Dysfunctional mechanical coupling of upper airway tissues in sleep apnea syndrome
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Quebec, Canada
    Am J Respir Crit Care Med 159:1551-5. 1999
    ..55, p = 0.007). We conclude that there is a significant difference between the uvular tissue elastance of SAHS and snorers, and that this difference influences the mechanical efficiency of MU contraction...
  22. ncbi request reprint Effects of inspiratory and expiratory positive pressure difference on airflow dynamics during sleep
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Sainte Foy, Quebec, Canada G1V 4G5
    J Appl Physiol (1985) 85:1855-62. 1998
    ..e., decreasing PE) may be associated with a significant worsening in inspiratory flow limitation and that the VImax-pressure difference behavior is not dependent on the GG electromyographic-pressure response...
  23. ncbi request reprint Discriminative power of phrenic twitch-induced dynamic response for diagnosis of sleep apnea during wakefulness
    Eric Verin
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada G1V 4G5
    J Appl Physiol 94:31-7. 2003
    ..7 ml. cmH(2)O x s(-1). These included five nonapneic and six apneic patients. We conclude that UA dynamic properties studied with BAMPS during wakefulness significantly differ between nonapneic and apneic patients...
  24. ncbi request reprint Influences of the breathing route on upper airway dynamics properties in normal awake subjects with constant mouth opening
    Wei Wang
    Centre Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada G1V 4G5
    Clin Sci (Lond) 111:349-55. 2006
    ..We conclude that (i) in the presence of MO the dynamic properties of the proximal UA free of phasic activity do not differ between NB and MB, and (ii) MB decreases the upstream resistance and increases collapsibility of the distal UA...
  25. doi request reprint Impact of CPAP interface and mandibular advancement device on upper airway mechanical properties assessed with phrenic nerve stimulation in sleep apnea patients
    Jean Christian Borel
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec, QC, Canada
    Respir Physiol Neurobiol 183:170-6. 2012
    ..In conclusion, NM+MAD reduced velopharyngeal resistance compared to those measured with ONM and NM alone. We hypothesize that this strategy may help reducing the effective pressure level and thus further limit the risk for mouth leaks...
  26. doi request reprint Assessment of upper airway dynamics by anterior magnetic phrenic stimulation in conscious sleep apnea patients
    César Augusto Melo-Silva
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et Pneumologie de Québec, Universite Laval, Quebec, QC, Canada
    J Appl Physiol (1985) 112:1345-52. 2012
    ..05 cmH(2)O·l(-1)·s(-1)) than with inward motion (4.3 ± 1.5 cmH(2)O·l(-1)·s(-1); P = 0.03). We conclude that a-MS represents a practical and functional technique to evaluate UA mechanical properties in conscious sleep apnea patients...
  27. pmc The effect of obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies
    Magali Poulain
    Division de kinesiologie, Departement de Medecine sociale et preventive, Universite Laval, Quebec, Que
    CMAJ 174:1293-9. 2006
    ....
  28. doi request reprint Influence of CO₂ on upper airway muscles and chest wall/diaphragm corticomotor responses assessed by transcranial magnetic stimulation in awake healthy subjects
    Jean Christian Borel
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec, Canada
    J Appl Physiol (1985) 112:798-805. 2012
    ..The aim of our study was to compare the effects of hypercapnic stimulation on diaphragm and genioglossus corticomotor responses to transcranial magnetic stimulation (TMS)...
  29. doi request reprint Relationship between atherosclerosis and the sleep apnea syndrome: an intravascular ultrasound study
    Julie Turmel
    Laval Hospital Quebec Heart Lung Institute, Quebec City, Canada
    Int J Cardiol 132:203-9. 2009
    ..Sleep apnea hypopnea syndrome (SAHS) is a predictive factor of cardiovascular disease. We hypothesized that SAHS could influence coronary atherosclerosis plaque volume as assessed by 3-dimensional intravascular ultrasound (3D-IVUS)...
  30. doi request reprint Consecutive transcranial magnetic stimulation twitches reduce flow limitation during sleep in apnoeic patients
    César Augusto Melo-Silva
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec, QC, Canada
    Exp Physiol 98:1366-75. 2013
    ....
  31. doi request reprint Acute upper airway muscle and inspiratory flow responses to transcranial magnetic stimulation during sleep in apnoeic patients
    César Augusto Melo-Silva
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec, QC, Canada
    Exp Physiol 98:946-56. 2013
    ..001) in all but one patient. Corticobulbar excitability of submental muscles decreases during NREM sleep. Brief recruitment of submental muscles with TMS during sleep improves upper airway mechanics without arousing patients from sleep...
  32. doi request reprint Influence of negative airway pressure on upper airway dynamic and impact on night-time apnea worsening
    Simon Gakwaya
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec City, Quebec, Canada G1V 4G5
    Respir Physiol Neurobiol 181:88-94. 2012
    ..We measured the effects of such loading on UA mechanical properties during wakefulness and assessed the potential link with night-time apnea worsening...
  33. doi request reprint Tumor necrosis factor-alpha expression in uvular tissues differs between snorers and apneic patients
    Lionel Loubaki
    Centre de Recherche, Hopital Laval, Insitute Universitaire de Cardiologie et de Pneumologie, Quebec, Canada
    Chest 134:911-8. 2008
    ..TNF-alpha has been shown to affect diaphragm contractility in mice and rabbit in vivo...
  34. pmc Effects of continuous positive airway pressure on upper airway inspiratory dynamics in awake patients with sleep-disordered breathing
    E Verin
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    J Physiol 546:279-87. 2003
    ..0 +/- 2.0; P(eff,stim) = 6.4 +/- 2.6 cmH(2)O; r = 0.886; 95 % CI 0.696-0.960, P < 0.001). We conclude that CPAP improves UA dynamics in OSAS and that the therapeutic CPAP to apply can be predicted during wakefulness using BAMPS...
  35. ncbi request reprint Interaction between genioglossus and diaphragm responses to transcranial magnetic stimulation in awake humans
    Wei Wang
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec City, Quebec, Canada
    Exp Physiol 92:739-47. 2007
    ....
  36. doi request reprint Evaluating nocturnal oxygen desaturation in COPD--revised
    Yves Lacasse
    Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Ste Foy, Quebec, Quebec G1V 4G5, Canada
    Respir Med 105:1331-7. 2011
    ..An understanding of the prevalence of nocturnal desaturation in COPD, in the absence of other respiratory co-morbidities, is an important step towards its standardized management...
  37. doi request reprint Impact of stepwise mandibular advancement on upper airway mechanics in obstructive sleep apnea using phrenic nerve magnetic stimulation
    Simon Gakwaya
    Unité de Recherche en Pneumologie, Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec, QC, Canada
    Respir Physiol Neurobiol 190:131-6. 2014
    ..These data suggest that mandibular advancement devices are acting predominantly at the velopharyngeal level. ..
  38. doi request reprint Sleep apnoea attenuates the effects of a lifestyle intervention programme in men with visceral obesity
    Anne Laure Borel
    Department of Pneumology, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec, Canada
    Thorax 67:735-41. 2012
    ..Excess visceral adiposity and sleep apnoea are two conditions independently associated with cardiovascular diseases. The two conditions are often combined and are believed to interact in a vicious circle...
  39. doi request reprint Prediction of oral appliance efficiency in patients with apnoea using phrenic nerve stimulation while awake
    Valerie Bosshard
    Unité de Recherche en Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Sainte Foy, Quebec, Canada
    Thorax 66:220-5. 2011
    ..Phrenic nerve stimulation is able to induce upper airway obstruction and was therefore used to mimic the target for an efficient treatment with an oral appliance...
  40. ncbi request reprint Usefulness of phrenic nerve stimulation to measure upper airway collapsibility in normal awake subjects
    C Sanfaçon
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, 2725 Chemin Sainte Foy, Sainte Foy, Quebec, Canada GW 4G5
    Respir Physiol Neurobiol 130:57-67. 2002
    ....
  41. pmc Unusual respiratory manifestations in two young adults with Duchenne muscular dystrophy
    Julie Lemay
    Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec
    Can Respir J 19:37-40. 2012
    ....
  42. doi request reprint Assessment of upper airway dynamic properties using sternal phrenic nerve magnetic stimulation in awake subjects
    Jean Christian Borel
    Unité de Recherche en Pneumologie, Centre de Recherche Institut Universitaire de Cardiologie et Pneumologie de Québec, Universite Laval, Canada
    Respir Physiol Neurobiol 178:218-22. 2011
    ..05) and isoflow UA resistance tended to be lesser with a-MS (0.9±0.3 and 1.8±0.7 cmH2Ol(-1)s; P=0.09). a-MS could be a practical approach for assessing UA dynamic properties in awake subjects...
  43. ncbi request reprint Does the energy expenditure status in obstructive sleep apnea favour a positive energy balance?
    Geneviève C Major
    Division of Kinesiology, Department of Social and Preventive Medicine, Faculty of Medicine, Universite Laval, Quebec City, Quebec, Canada
    Clin Invest Med 30:E262-8. 2007
    ..The objective of this study was to assess the relationship between 24-hr energy expenditure or sleeping metabolic rate and features of the obstructive sleep apnea...
  44. ncbi request reprint Health-related quality of life in obstructive sleep apnoea
    Y Lacasse
    Centre de Recherche, Centre de Pneumologie, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Eur Respir J 19:499-503. 2002
    ..Obstructive sleep apnoea significantly contributes to the impairment of all domains of what is usually referred to as "health-related quality of life"...
  45. pmc Independent validation of the Sleep Apnoea Quality of Life Index
    Y Lacasse
    Centre de Recherche, Centre de Pneumologie, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Thorax 57:483-8. 2002
    ..The objective of this study was to examine the measurement properties (both discriminative and evaluative) of the Sleep Apnoea Quality of Life Index (SAQLI), a new OSA specific quality of life questionnaire...
  46. ncbi request reprint Mechanisms of the effectiveness of continuous positive airway pressure in obstructive sleep apnea
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Sleep 15:S47-9. 1992
    ..An improvement in central chemosensitivity could account for the improvement in diurnal oxygenation observed with long term NCPAP therapy...
  47. ncbi request reprint [Health-related quality of life measurement: a readers' guide]
    Y Lacasse
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Quebec, Canada
    Rev Mal Respir 21:S63-70. 2004
  48. ncbi request reprint Effects of mouth opening on upper airway collapsibility in normal sleeping subjects
    J C Meurice
    Unite de Recherche, Hopital Laval, Universite Laval Quebec, Sainte Foy, Canada
    Am J Respir Crit Care Med 153:255-9. 1996
    ..We conclude that mouth opening increases UA collapsibility during sleep and that mouth opening may contribute to the occurrence of sleep-related breathing abnormalities...
  49. doi request reprint Gestational diabetes mellitus and sleep-disordered breathing
    Michèle Bisson
    Department of Pediatrics, Centre Hospitalier Universitaire de Quebec, The Research Centre, Institut Universitaire de Cardiologie et Pneumologie de Québec, and the Departments of Medical Biology and Endocrinology, CHU de Québec, Universite Laval, Quebec City, and the Sleep Laboratory, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Obstet Gynecol 123:634-41. 2014
    ..To examine the link between gestational diabetes mellitus (GDM) and sleep-disordered breathing using complete polysomnography and questionnaires in a case-control study of pregnant women...
  50. pmc Nocturnal oxygen therapy in patients with chronic obstructive pulmonary disease: a survey of Canadian respirologists
    Yves Lacasse
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Sainte Foy, Quebec
    Can Respir J 14:343-8. 2007
    ....
  51. ncbi request reprint Evaluation of treatment efficacy in sleep apnea hypopnea syndrome
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Sleep 19:S71-6. 1996
    ....
  52. ncbi request reprint Relationship between severity of nocturnal desaturation and adaptive thermogenesis: preliminary data of apneic patients tested in a whole-body indirect calorimetry chamber
    J Hins
    Division de kinesiologie, Departement de Medecine sociale et preventive, Universite Laval, Ste Foy, Quebec, Canada
    Int J Obes (Lond) 30:574-7. 2006
    ..74, P < 0.05) and a similar negative trend with SMR (r = -0.65, P = 0.08). These preliminary data suggest that a nocturnal hypoxia may influence adaptive thermogenesis in apneic patients and complicate their body weight regulation...
  53. pmc Position paper by Canadian dental sleep medicine professionals on the role of different health care professionals in managing obstructive sleep apnea and snoring with oral appliances
    Luc Gauthier
    Centre de santé et de services sociaux de Chicoutimi, 304 Rue St Vallier, Chicoutimi, Quebec, Canada
    Can Respir J 19:307-9. 2012
    ..Many of the dentists and sleep physicians who contributed to the preparation of the present article are members of the Canadian Sleep Society and the authors reached a consensus based on the current literature...
  54. ncbi request reprint Accuracy of breath-by-breath analysis of flow-volume loop in identifying sleep-induced flow-limited breathing cycles in sleep apnoea-hypopnoea syndrome
    F Series
    Unite de Recherche, l Hôpital Laval, Universite Laval, Quebec, Canada
    Clin Sci (Lond) 88:707-12. 1995
    ..97, the sensitivity and specificity of the method were both 76%. In each subject, the proportion of breathing cycles identified as flow-progressively decreased with an increasing positive pressure level.(ABSTRACT TRUNCATED AT 250 WORDS)..
  55. doi request reprint Sibutramine versus continuous positive airway pressure in obese obstructive sleep apnoea patients
    A Ferland
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, QC, Canada
    Eur Respir J 34:694-701. 2009
    ..Sibutramine did not improve sleep-disordered breathing, systemic blood pressure or heart rate variability. There were no adverse effects, such as increment in blood pressure or arrhythmias, associated with this treatment regimen...
  56. ncbi request reprint Is there an association between coronary atherosclerosis and airway responsiveness?
    Julie Turmel
    Laval Hospital Quebec Heart Lung Institute, Quebec City, Montreal, Canada
    Acta Cardiol 63:347-53. 2008
    ..Our objective was to assess the potential relationship between AHR and coronary atherosclerosis plaque volume as assessed by 3-dimensional intravascular ultrasound (IVUS)...
  57. ncbi request reprint Impact of CPAP on asthmatic patients with obstructive sleep apnoea
    C LaFond
    Sacre Coeur Hospital, University of Montreal, Montreal, Quebec City, QC, Canada
    Eur Respir J 29:307-11. 2007
    ..However, nocturnal continuous positive airway pressure treatment did improve asthma quality of life...
  58. ncbi request reprint Long-term effects of protriptyline in patients with chronic obstructive pulmonary disease
    F Series
    Unite de Recherche, Hopital Laval, Universite Laval, Quebec, Canada
    Am Rev Respir Dis 147:1487-90. 1993
    ..In both groups the cumulative SaO2 curves were similar to those obtained at baseline.(ABSTRACT TRUNCATED AT 250 WORDS)..
  59. ncbi request reprint Auto CPAP in the treatment of sleep apnea hypopnea syndrome
    F Series
    Unite de Recherche, Centre de Pneumologie de l Hôpital Laval, Universite Laval, Quebec, Canada
    Sleep 19:S281-3. 1996
    ..Auto CPAP may be an effective alternative to conventional CPAP and preliminary results suggest that the Morphée Plus apparatus may be used accurately without titration sleep study by estimating the reference pressure...
  60. ncbi request reprint Effects of protriptyline on diurnal and nocturnal oxygenation in patients with chronic obstructive pulmonary disease
    F Series
    Centre de Pneumologie, Hopital Laval, Quebec, Canada
    Ann Intern Med 113:507-11. 1990
    ....
  61. ncbi request reprint Effects of lung volume and positive airway pressure on collateral resistance
    Y Cormier
    Unite de Recherche, Centre de Pneumologie, Hôpital and Université Laval, Quebec, Canada
    Respir Physiol 80:103-12. 1990
    ..We conclude that resistance to collateral flow is highly dependent on lung volume, and that positive airway pressure decreases Rcoll by its effects on lung volume...
  62. ncbi request reprint Importance of sleep stage- and body position-dependence of sleep apnoea in determining benefits to auto-CPAP therapy
    F Series
    Unité De Recherche Centre de pneumologie, Hopital Laval, Universite Laval, Quebec, Canada
    Eur Respir J 18:170-5. 2001
    ..It is concluded that auto-continuous positive airway pressure may have specific indications in a subset of obstructive sleep apnoea patients with sleep stage- and body position dependent nocturnal breathing abnormalities...
  63. ncbi request reprint Increasing the functional residual capacity may reverse obstructive sleep apnea
    F Series
    Centre de Pneumologie, Hopital Laval, Sainte Foy, Quebec, Canada
    Sleep 11:349-53. 1988
    ..Our observation illustrates that lung volumes may be an important factor in the pathophysiology of obstructive sleep apnea, especially in the apnea onset and in the apneic-induced desaturation...
  64. pmc Changes in day and night time oxygenation with protriptyline in patients with chronic obstructive lung disease
    F Series
    Centre de Pneumologie, Hopital Laval, Sainte Foy, Quebec, Canada
    Thorax 44:275-9. 1989
    ..These results suggest that protriptyline may benefit patients with chronic obstructive lung disease by reducing the sleep induced falls in SaO2 and improving diurnal PaO2; a controlled trial is now required...