W Vogel

Summary

Affiliation: Samuel Lunenfeld Research Institute
Country: Canada

Publications

  1. ncbi request reprint Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584
    W Vogel
    Department of Molecular Biology, Max Planck Institut für Blochemie, Martinsried, Germany
    Cell Growth Differ 7:1589-97. 1996
  2. ncbi request reprint Discoidin domain receptors: structural relations and functional implications
    W Vogel
    Programme in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada
    FASEB J 13:S77-82. 1999
  3. ncbi request reprint Discoidin domain receptor 1 is activated independently of beta(1) integrin
    W Vogel
    Programme in Molecular Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada
    J Biol Chem 275:5779-84. 2000
  4. ncbi request reprint Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation
    W Vogel
    Department of Molecular Biology, Max Planck Institut fur Biochemie, Martinsried, Germany
    Science 259:1611-4. 1993
  5. ncbi request reprint The discoidin domain receptor tyrosine kinases are activated by collagen
    W Vogel
    Programme in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Mol Cell 1:13-23. 1997
  6. pmc The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair
    G Hou
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, M5S 1A8, Canada
    J Clin Invest 107:727-35. 2001
  7. ncbi request reprint Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
    A M Cheng
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Cell 95:793-803. 1998
  8. ncbi request reprint Distribution of DMT 1 within the human glandular system
    R O Koch
    Division of Gastroenterology and Hepatology, University Hospital of Innsbruck, Austria
    Histol Histopathol 18:1095-101. 2003
  9. ncbi request reprint Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox
    A M Heegaard
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Bone Miner Res 12:2050-60. 1997

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584
    W Vogel
    Department of Molecular Biology, Max Planck Institut für Blochemie, Martinsried, Germany
    Cell Growth Differ 7:1589-97. 1996
    ..Immunoprecipitation of SHP-2 from a panel of mammary carcinoma cell lines copurifies several tyrosine phosphorylated proteins; the most prominent band has an apparent molecular weight of M(r) 115,000...
  2. ncbi request reprint Discoidin domain receptors: structural relations and functional implications
    W Vogel
    Programme in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada
    FASEB J 13:S77-82. 1999
    ..The potential cross-talk to other receptors for collagen and the clinical aspects of DDR function are discussed...
  3. ncbi request reprint Discoidin domain receptor 1 is activated independently of beta(1) integrin
    W Vogel
    Programme in Molecular Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada
    J Biol Chem 275:5779-84. 2000
    ..Finally, we show that overexpression of dominant negative DDR1 in the myoblast cell line C2C12 blocks cellular differentiation and the formation of myofibers...
  4. ncbi request reprint Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation
    W Vogel
    Department of Molecular Biology, Max Planck Institut fur Biochemie, Martinsried, Germany
    Science 259:1611-4. 1993
    ..Thus, protein tyrosine kinases and phosphatases do not simply oppose each other's action; rather, they may work in concert to maintain a fine balance of effector activation needed for the regulation of cell growth and differentiation...
  5. ncbi request reprint The discoidin domain receptor tyrosine kinases are activated by collagen
    W Vogel
    Programme in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Mol Cell 1:13-23. 1997
    ..These results suggest that the discoidin-related DDR tyrosine kinases are novel collagen receptors with the potential to control cellular responses to the extracellular matrix...
  6. pmc The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair
    G Hou
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, M5S 1A8, Canada
    J Clin Invest 107:727-35. 2001
    ..Our results support the hypothesis that DDR1 plays an important role as a collagen receptor, mediating intimal thickening after vascular injury...
  7. ncbi request reprint Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
    A M Cheng
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Cell 95:793-803. 1998
    ..These data provide genetic evidence for a mammalian Grb2-Ras signaling pathway, mediated by SH2/SH3 domain interactions, that has multiple functions in embryogenesis and cancer...
  8. ncbi request reprint Distribution of DMT 1 within the human glandular system
    R O Koch
    Division of Gastroenterology and Hepatology, University Hospital of Innsbruck, Austria
    Histol Histopathol 18:1095-101. 2003
    ..Background &..
  9. ncbi request reprint Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox
    A M Heegaard
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Bone Miner Res 12:2050-60. 1997
    ..This is the first detection of c-Krox in bone cells, and it suggests that c-Krox, like another member of the Krox family, Krox-20, might play a regulatory role in bone...