Tony Pawson


Affiliation: Samuel Lunenfeld Research Institute
Country: Canada


  1. request reprint
    Li S, Lai K, Gish G, Parris W, van der Geer P, Forman Kay J, et al. Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein. J Biol Chem. 1996;271:31855-62 pubmed
    ..The invertebrate dShc PTB domain therefore possesses a binding specificity for tyrosine-phosphorylated peptides that is optimally suited for recognition of the activated DER receptor. ..
  2. request reprint
    Pawson T, Nash P. Protein-protein interactions define specificity in signal transduction. Genes Dev. 2000;14:1027-47 pubmed
  3. Jones N, Hardy W, Friese M, Jorgensen C, Smith M, Woody N, et al. Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase. Mol Cell Biol. 2007;27:4759-73 pubmed
    ..Thus, we have characterized a new member of the Shc family of docking proteins, which may mediate a specific aspect of signaling downstream of the MuSK receptor. ..