Affiliation: Samuel Lunenfeld Research Institute
- PreBIND and Textomy--mining the biomedical literature for protein-protein interactions using a support vector machineIan Donaldson
Samuel Lunenfeld Research Institute, Toronto, M5G 1X5, Canada
BMC Bioinformatics 4:11. 2003..We present an information extraction system that was designed to locate protein-protein interaction data in the literature and present these data to curators and the public for review and entry into BIND...
- SeqHound: biological sequence and structure database as a platform for bioinformatics researchKaterina Michalickova
Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5S 1A8
BMC Bioinformatics 3:32. 2002..SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for bioinformatics research in a locally-hosted environment...
- Species-specific protein sequence and fold optimizationsMichel Dumontier
Department of Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada
BMC Bioinformatics 3:39. 2002..In the largest study of its kind, we sought to identify and exploit the amino-acid signatures that make species-specific protein adaptation possible across 100 complete genomes...
- Mutation profiling of mismatch repair-deficient colorectal cncers using an in silico genome scan to identify coding microsatellitesJane Park
Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and Department of Laboratory Medicine University of Toronto, Toronto, Ontario, Canada M5G 1X5
Cancer Res 62:1284-8. 2002..This algorithm allows comprehensive mutation profiling of MMR-deficient cancers, an important step in understanding the pathogenesis of these neoplasms...