Stephane Roy

Summary

Country: Canada

Publications

  1. ncbi Cyclopamine induces digit loss in regenerating axolotl limbs
    Stephane Roy
    Developmental Biology Center and Department of Developmental Cell Biology, University of California at Irvine, Irvine, California 92697, USA
    J Exp Zool 293:186-90. 2002
  2. ncbi BMP-2 functions independently of SHH signaling and triggers cell condensation and apoptosis in regenerating axolotl limbs
    Jean Charles Guimond
    Department of Stomatology, Faculty of Dentistry, Universite de Montreal, Montreal Qc Canada
    BMC Dev Biol 10:15. 2010
  3. ncbi Regeneration in axolotls: a model to aim for!
    Stephane Roy
    Department of Stomatology, Faculty of Dentistry, Universite de Montreal, Down Town Branch, Montreal, QC, Canada
    Exp Gerontol 43:968-73. 2008
  4. ncbi Limb regeneration in axolotl: is it superhealing?
    Stephane Roy
    Department of Stomatology, Faculty of Dentistry, Universite de Montreal, C P 6128 Succursale Centre Ville Montréal, Québec Canada H3C 3J7
    ScientificWorldJournal 6:12-25. 2006
  5. ncbi Transforming growth factor: beta signaling is essential for limb regeneration in axolotls
    Mathieu Lévesque
    Department of Biochemistry, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 2:e1227. 2007
  6. ncbi Expression of heat-shock protein 70 during limb development and regeneration in the axolotl
    Mathieu Lévesque
    Department of Biochemistry, Universite de Montreal, Quebec, Canada
    Dev Dyn 233:1525-34. 2005
  7. ncbi Skin wound healing in axolotls: a scarless process
    Mathieu Lévesque
    Department of Biochemistry, Universite de Montreal, Succursale Centre Ville, Montreal, QC, Canada
    J Exp Zool B Mol Dev Evol 314:684-97. 2010
  8. ncbi Analysis of the expression and function of Wnt-5a and Wnt-5b in developing and regenerating axolotl (Ambystoma mexicanum) limbs
    Sukla Ghosh
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California at Irvine, California 92697, USA
    Dev Growth Differ 50:289-97. 2008
  9. ncbi Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer
    Eric Villiard
    Department of Biochemistry, Faculty of Medicine, Universite de Montreal, Montreal, QC, H3C 3J7, Canada
    BMC Evol Biol 7:180. 2007
  10. ncbi The axolotl limb: a model for bone development, regeneration and fracture healing
    Cara Hutchison
    Department of Biochemistry, Universite de Montreal, Quebec, Canada
    Bone 40:45-56. 2007

Collaborators

  • Eric Villiard
  • D M Gardiner
  • Thomas Mustoe
  • Mathieu Lévesque
  • Anie Philip
  • Jean Charles Guimond
  • Mireille Pilote
  • Joshua Vorstenbosch
  • Kenneth Finnson
  • Sukla Ghosh
  • Cara Hutchison
  • Alissa Trzeciak
  • Corrie Gallant-Behm
  • Jérémie Berdugo
  • Pierre Luc Michaud
  • Susan V Bryant
  • CARL SEGUIN
  • Sophie Desmeules
  • Samuel Gatien
  • Florina Moldovan
  • Severine Leclerc
  • Jean-Charles Guimond

Detail Information

Publications11

  1. ncbi Cyclopamine induces digit loss in regenerating axolotl limbs
    Stephane Roy
    Developmental Biology Center and Department of Developmental Cell Biology, University of California at Irvine, Irvine, California 92697, USA
    J Exp Zool 293:186-90. 2002
    ..Our results further demonstrate that shh signaling and function are conserved during limb regeneration in urodeles as in limb development in other vertebrates...
  2. ncbi BMP-2 functions independently of SHH signaling and triggers cell condensation and apoptosis in regenerating axolotl limbs
    Jean Charles Guimond
    Department of Stomatology, Faculty of Dentistry, Universite de Montreal, Montreal Qc Canada
    BMC Dev Biol 10:15. 2010
    ....
  3. ncbi Regeneration in axolotls: a model to aim for!
    Stephane Roy
    Department of Stomatology, Faculty of Dentistry, Universite de Montreal, Down Town Branch, Montreal, QC, Canada
    Exp Gerontol 43:968-73. 2008
    ....
  4. ncbi Limb regeneration in axolotl: is it superhealing?
    Stephane Roy
    Department of Stomatology, Faculty of Dentistry, Universite de Montreal, C P 6128 Succursale Centre Ville Montréal, Québec Canada H3C 3J7
    ScientificWorldJournal 6:12-25. 2006
    ..A better understanding of these animals' regenerative capacity could lead to major benefits by providing regenerative medicine with directions on how to develop therapeutic approaches leading to regeneration in humans...
  5. ncbi Transforming growth factor: beta signaling is essential for limb regeneration in axolotls
    Mathieu Lévesque
    Department of Biochemistry, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 2:e1227. 2007
    ..These data directly implicate TGF-beta signaling in the initiation and control of the regeneration process in axolotls...
  6. ncbi Expression of heat-shock protein 70 during limb development and regeneration in the axolotl
    Mathieu Lévesque
    Department of Biochemistry, Universite de Montreal, Quebec, Canada
    Dev Dyn 233:1525-34. 2005
    ..We also demonstrate a similar pattern of expression for the protein during regeneration. Finally, we show that axolotl Hsp-70 is induced threefold after heat-shock as observed in other vertebrates...
  7. ncbi Skin wound healing in axolotls: a scarless process
    Mathieu Lévesque
    Department of Biochemistry, Universite de Montreal, Succursale Centre Ville, Montreal, QC, Canada
    J Exp Zool B Mol Dev Evol 314:684-97. 2010
    ..Surprisingly, results show that axolotls are not resistant to bleomycin-induced tissue fibrosis, but the resulting scar tissue does not seem to contain significant amounts of collagen...
  8. ncbi Analysis of the expression and function of Wnt-5a and Wnt-5b in developing and regenerating axolotl (Ambystoma mexicanum) limbs
    Sukla Ghosh
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California at Irvine, California 92697, USA
    Dev Growth Differ 50:289-97. 2008
    ....
  9. ncbi Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer
    Eric Villiard
    Department of Biochemistry, Faculty of Medicine, Universite de Montreal, Montreal, QC, H3C 3J7, Canada
    BMC Evol Biol 7:180. 2007
    ..Urodele amphibians like the axolotl are unique among vertebrates in their ability to regenerate and their resistance to develop cancers. It is unknown whether these traits are linked at the molecular level...
  10. ncbi The axolotl limb: a model for bone development, regeneration and fracture healing
    Cara Hutchison
    Department of Biochemistry, Universite de Montreal, Quebec, Canada
    Bone 40:45-56. 2007
    ..These results suggest that the axolotl does not use the regeneration process to repair bone fractures...
  11. ncbi Transgenic mice overexpressing CD109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing
    Joshua Vorstenbosch
    Department of Surgery, Division of Plastic Surgery, McGill University, Montreal, Quebec, Canada
    Wound Repair Regen 21:235-46. 2013
    ..Taken together, our findings demonstrate that CD109 overexpression in the epidermis reduces inflammation and granulation tissue area and improves collagen organization in vivo...