Research Topics
Species | M A RoySummaryCountry: Canada Publications
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Detail Information
Publications
Clinical and methodological factors related to reliability of the best-estimate diagnostic procedureM A Roy
Centre de Recherche Universite Laval Robert Giffard, Beauport, Quebec, Canada
Am J Psychiatry 154:1726-33. 1997..The reliability and accuracy of the best-estimate diagnostic procedure were examined, and factors associated with reliability were determined...
Subtyping schizophrenia according to outcome or severity: a search for homogeneous subgroupsM A Roy
Department of Psychiatry, Universite Laval, Quebec, Canada
Schizophr Bull 27:115-38. 2001..We propose ten methodological and conceptual recommendations for future studies aimed at the identification of valid SZ subtypes according to outcome or severity...
Male gender is associated with deficit schizophrenia: a meta-analysisM A Roy
Centre de Recherche Universite Laval Robert Giffard, département de Psychiatrie de la faculté de Médecine de l Université Laval, Robert Giffard, 2601 de la Canardiere, Beauport, G1J 2G3, Quebec, Canada
Schizophr Res 47:141-7. 2001..g. sexual hormones) or gender differences in the liability to different etiologies of schizophrenia. The role of gender as a potential confounder must be closely examined in studies comparing deficit and non-deficit SZ...
A genome wide linkage study of obesity as secondary effect of antipsychotics in multigenerational families of eastern Quebec affected by psychosesY C Chagnon
Laval University Research Center Robert Giffard, Beauport, Québec G1J 2B3, Canada
Mol Psychiatry 9:1067-74. 2004..PMCH encodes a neuropeptide involved in the control of food intake, energy expenditure, and in anxiety/depression. This first genome scan targeting the obesity side effect of antipsychotics identified 12q24 as a susceptibility region...
6p24-22 region and major psychoses in the Eastern Quebec population. Le Groupe IREPM Maziade
Centre de Recherche Universite Laval Robert Giffard, Beauport, Quebec, Canada
Am J Med Genet 74:311-8. 1997....
Significant linkage for Tourette syndrome in a large French Canadian familyC Merette
Centre de Recherche Universite Laval Robert Giffard, Beauport, Quebec, G1J 2G3 Canada
Am J Hum Genet 67:1008-13. 2000..18. Hence, even after adjustment for multiple testing, the present study shows statistically significant evidence for genetic linkage with TS...
A search for specific and common susceptibility loci for schizophrenia and bipolar disorder: a linkage study in 13 target chromosomesM Maziade
Centre de Recherche Universite Laval Robert Giffard, 2601, chemin de la Canardiere, Beauport Québec G1J 2G3, Canada
Mol Psychiatry 6:684-93. 2001..The 6p finding provided confirmatory evidence of linkage for SZ. Our results suggest that both specific and common susceptibility loci must be searched for SZ and BP...
Possible association of the pro-melanin-concentrating hormone gene with a greater body mass index as a side effect of the antipsychotic olanzapineY C Chagnon
Laval University Robert Giffard Research Center, Quebec, Canada
Am J Med Genet B Neuropsychiatr Genet 144:1063-9. 2007..No association was observed for those over 50 years, or for rs11111201. These results suggest that the common allele of PMCH rs7973796 may be associated with a greater BMI in olanzapine-treated SZ patients...
Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec familiesM Maziade
Department of Psychiatry, Laval University, Quebec G1J 2G3, Canada
Mol Psychiatry 10:486-99. 2005..The present results support the relevance of investigating concurrently SZ and BP within the same study and have implications for the modelling of genetic effects...
Selecting a control group in studies of the familial coaggregation of two disorders: a quantitative genetics perspectiveM A Roy
Departement de Psychiatrie, Centre Hospitalier Robert Giffard and Centre de Recherche, Université Laval Robert Giffard, Beauport, Quebec, Canada
Am J Med Genet 74:296-303. 1997..Moreover, quantitative genetics methods may offer important advantages in the study of familial coaggregation...
Anticipation in schizophrenia and bipolar disorder controlling for an information biasC Merette
Centre de Recherche Universite Laval Robert Giffard, Quebec, Canada
Am J Med Genet 96:61-8. 2000..Findings suggest that future anticipation studies should also control for QOI. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:61-68, 2000...
Clinical diagnoses in young offspring from eastern Québec multigenerational families densely affected by schizophrenia or bipolar disorderM Maziade
Centre de Recherche Universite Laval Robert Giffard, QC, Canada
Acta Psychiatr Scand 117:118-26. 2008....
Prolongation of brainstem auditory-evoked responses in autistic probands and their unaffected relativesM Maziade
or Michel Maziade, MD, FRCP C, Centre de Recherche Universite Laval Robert Giffard, 2601, chemin de la Canardiere, Beauport, Québec G1J 2G3 Canada
Arch Gen Psychiatry 57:1077-83. 2000..Autism also has strong genetic determinants, and like all major psychiatric disorders, its complex clinical phenotype renders genetic studies difficult. Innovative strategies focused on alternative biological phenotypes are needed...
Differential RNA expression between schizophrenic patients and controls of the dystrobrevin binding protein 1 and neuregulin 1 genes in immortalized lymphocytesY C Chagnon
Laval University Research Center Robert Giffard, Quebec, Quebec, Canada
Schizophr Res 100:281-90. 2008..86, respectively), but was slightly repressed by olanzapine in controls (-8%; p=0.008) but not in SZ (+1%; p=0.91). These results are in agreement with those observed in post-mortem brain when the isoforms involved are considered...
[Perturbed consciousness in schizophrenia: an evaluation of C.D. Frith's model]M Roy
Ecole de Psychologie, Universite Laval, Quebec G1K 7P4, Canada
Encephale 34:369-75. 2008..While many neurocognitive models of schizophrenia coexist, a lot of attention has been centered on C.D. Frith's model over the past few years, especially in regard to its parsimony...
Actual vs. best practices for young children with cerebral palsy: a survey of paediatric occupational therapists and physical therapists in Quebec, CanadaM N Saleh
School of Physical and Occupational Therapy, Faculty of Medicine, McGill University and Centre de recherche interdisciplinaire en réadaptation du Montréal métropolitain, Montreal, Quebec, Canada
Dev Neurorehabil 11:60-80. 2008..This study describes OT and PT practices for young children with CP in Quebec, Canada...
