H S Mayberg

Summary

Affiliation: Rotman Research Institute
Country: Canada

Publications

  1. ncbi request reprint The functional neuroanatomy of the placebo effect
    Helen S Mayberg
    Department of Psychiatry, University of Texas at San Antonio, USA
    Am J Psychiatry 159:728-37. 2002
  2. ncbi request reprint Personality influences limbic-cortical interactions during sad mood induction
    Michelle L Keightley
    Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    Neuroimage 20:2031-9. 2003
  3. ncbi request reprint Positron emission tomography imaging in depression: a neural systems perspective
    Helen S Mayberg
    Department of Psychiatry and Medicine Neurology, Rotman Research Institute, Baycrest Centre, University of Toronto, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada
    Neuroimaging Clin N Am 13:805-15. 2003
  4. ncbi request reprint Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness
    H S Mayberg
    Research Imaging Center, University of Texas Health Science Center at San Antonio, USA
    Am J Psychiatry 156:675-82. 1999
  5. ncbi request reprint The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study
    J H Meyer
    Clarke Division, Centre for Addictions and Mental Health, Department ofPsychiatry, University of Toronto, Ontario, Canada
    Am J Psychiatry 158:78-85. 2001
  6. ncbi request reprint Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression
    S H Kennedy
    Mood and Anxiety Disorders Program, Centre for Addiction and Mental Health, Clarke Site, 250 College St, Toronto, Ontario M5T 1R8, Canada
    Am J Psychiatry 158:899-905. 2001
  7. ncbi request reprint The role of functional neuroimaging in the neuropsychology of depression
    M Liotti
    Research Imaging Center, and Department of Radiology, Psychiatry and Medicine Neurology, University of Texas Health Science Center, San Antonio, TX, USA
    J Clin Exp Neuropsychol 23:121-36. 2001
  8. ncbi request reprint Xenon effects on regional cerebral blood flow assessed by 15O-H2O positron emission tomography: implications for hyperpolarized xenon MRI
    M Liotti
    Research Imaging Center, University of Texas Health Science Center at San Antonio 78284 6240, USA
    J Magn Reson Imaging 7:761-4. 1997
  9. ncbi request reprint Modulating limbic-cortical circuits in depression: targets of antidepressant treatments
    Helen S Mayberg
    Department of Psychiatry, University of Toronto, Ontario, Canada
    Semin Clin Neuropsychiatry 7:255-68. 2002
  10. ncbi request reprint Differences in brain glucose metabolism between responders to CBT and venlafaxine in a 16-week randomized controlled trial
    Sidney H Kennedy
    University Health Network, Institute of Medical Science, University of Toronto, Department of Psychiatry, and Toronto General Hospital, 200 Elizabeth St, Eaton North Wing 8 222, Toronto, Ontario M5G 2C4, Canada
    Am J Psychiatry 164:778-88. 2007

Collaborators

Detail Information

Publications31

  1. ncbi request reprint The functional neuroanatomy of the placebo effect
    Helen S Mayberg
    Department of Psychiatry, University of Texas at San Antonio, USA
    Am J Psychiatry 159:728-37. 2002
    ..Administration of placebo can result in a clinical response indistinguishable from that seen with active antidepressant treatment. Functional brain correlates of this phenomenon have not been fully characterized...
  2. ncbi request reprint Personality influences limbic-cortical interactions during sad mood induction
    Michelle L Keightley
    Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    Neuroimage 20:2031-9. 2003
    ....
  3. ncbi request reprint Positron emission tomography imaging in depression: a neural systems perspective
    Helen S Mayberg
    Department of Psychiatry and Medicine Neurology, Rotman Research Institute, Baycrest Centre, University of Toronto, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada
    Neuroimaging Clin N Am 13:805-15. 2003
    ..An additional goal is the development of routine, brain-based clinical algorithms that optimize diagnosis and treatment of individual depressed patients...
  4. ncbi request reprint Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness
    H S Mayberg
    Research Imaging Center, University of Texas Health Science Center at San Antonio, USA
    Am J Psychiatry 156:675-82. 1999
    ..Expanding on this theory, this study examined functional interactions between specific limbic and neocortical regions accompanying normal and disease-associated shifts in negative mood state...
  5. ncbi request reprint The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study
    J H Meyer
    Clarke Division, Centre for Addictions and Mental Health, Department ofPsychiatry, University of Toronto, Ontario, Canada
    Am J Psychiatry 158:78-85. 2001
    ..The objective of this study was to evaluate the effect of 6 weeks of paroxetine treatment on 5-HT(2A) receptors in depressed patients...
  6. ncbi request reprint Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression
    S H Kennedy
    Mood and Anxiety Disorders Program, Centre for Addiction and Mental Health, Clarke Site, 250 College St, Toronto, Ontario M5T 1R8, Canada
    Am J Psychiatry 158:899-905. 2001
    ..The aim of the present study was to assess the effects of successful paroxetine treatment on regional glucose metabolism in patients with major depression...
  7. ncbi request reprint The role of functional neuroimaging in the neuropsychology of depression
    M Liotti
    Research Imaging Center, and Department of Radiology, Psychiatry and Medicine Neurology, University of Texas Health Science Center, San Antonio, TX, USA
    J Clin Exp Neuropsychol 23:121-36. 2001
    ....
  8. ncbi request reprint Xenon effects on regional cerebral blood flow assessed by 15O-H2O positron emission tomography: implications for hyperpolarized xenon MRI
    M Liotti
    Research Imaging Center, University of Texas Health Science Center at San Antonio 78284 6240, USA
    J Magn Reson Imaging 7:761-4. 1997
    ..No such decreases were found in other sensory or motor regions...
  9. ncbi request reprint Modulating limbic-cortical circuits in depression: targets of antidepressant treatments
    Helen S Mayberg
    Department of Psychiatry, University of Toronto, Ontario, Canada
    Semin Clin Neuropsychiatry 7:255-68. 2002
    ....
  10. ncbi request reprint Differences in brain glucose metabolism between responders to CBT and venlafaxine in a 16-week randomized controlled trial
    Sidney H Kennedy
    University Health Network, Institute of Medical Science, University of Toronto, Department of Psychiatry, and Toronto General Hospital, 200 Elizabeth St, Eaton North Wing 8 222, Toronto, Ontario M5G 2C4, Canada
    Am J Psychiatry 164:778-88. 2007
    ..In this study, the authors report changes in fluorine-18-fluorodeoxyglucose PET in responders to CBT or venlafaxine during a randomized controlled trial...
  11. ncbi request reprint Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder
    S L Rauch
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 50:659-67. 2001
    ..Further research, utilizing a prospective design, is indicated to determine the validity and reliability of this finding. If confirmed, an index for noninvasively predicting response to cingulotomy for OCD would be of great value...
  12. ncbi request reprint Limbic-frontal circuitry in major depression: a path modeling metanalysis
    D A Seminowicz
    Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 22:409-18. 2004
    ....
  13. ncbi request reprint An ERP study of the temporal course of the Stroop color-word interference effect
    M Liotti
    University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284 6240, USA
    Neuropsychologia 38:701-11. 2000
    ....
  14. doi request reprint Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression
    Andres M Lozano
    Division of Neurosurgery, University of Toronto, Toronto, Canada
    Biol Psychiatry 64:461-7. 2008
    ..We now report the results of these and an additional 14 patients with extended follow-up...
  15. doi request reprint Treatment resistant depression as a failure of brain homeostatic mechanisms: implications for deep brain stimulation
    Peter Giacobbe
    Department of Psychiatry, University Health Network, University of Toronto, Canada
    Exp Neurol 219:44-52. 2009
    ....
  16. ncbi request reprint Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression
    Darin D Dougherty
    Department of Psychiatry, Radiology, Neurosurgery, and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    J Neurosurg 99:1010-7. 2003
    ..The purpose of this study was to identify possible neuroimaging predictors of treatment response to anterior cingulotomy in patients with major depression...
  17. ncbi request reprint Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment
    Helen S Mayberg
    Department of Psychiatry and the Rotman Research Institute, University of Toronto, Ontario, Canada
    Br Med Bull 65:193-207. 2003
    ....
  18. ncbi request reprint Risk and resilience markers in bipolar disorder: brain responses to emotional challenge in bipolar patients and their healthy siblings
    Stephanie Krüger
    Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    Am J Psychiatry 163:257-64. 2006
    ..In this study, potential markers of bipolar risk and resilience were examined in a new cohort of lithium-responsive bipolar patients and their healthy siblings...
  19. doi request reprint Neural stimulation successfully treats depression in patients with prior ablative cingulotomy
    Joseph S Neimat
    Toronto Western Hospital, 399 Bathurst St, WW4 425, Toronto, Ontario M5T 2S8, Canada
    Am J Psychiatry 165:687-93. 2008
  20. ncbi request reprint Relationship between regional brain metabolism, illness severity and age in depressed subjects
    Jakub Z Konarski
    Institute of Medical Science, University of Toronto, Toronto, ON, Canada
    Psychiatry Res 155:203-10. 2007
    ..The age-dependent changes documented herein may influence the distinct clinical presentation and treatment response described in older-age depression...
  21. ncbi request reprint An fMRI study investigating cognitive modulation of brain regions associated with emotional processing of visual stimuli
    Michelle L Keightley
    Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ont, M6A 2E1 Canada
    Neuropsychologia 41:585-96. 2003
    ....
  22. ncbi request reprint Changes in regional cerebral blood flow following mood challenge in drug-free, remitted patients with unipolar depression
    Michael C Gemar
    Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    Depress Anxiety 24:597-601. 2007
    ..Previously reported mediofrontal changes in remitted patients are unlikely to be a consequence of maintenance medication and more likely are evidence of relapse vulnerability...
  23. ncbi request reprint Neurobiological mechanisms of the placebo effect
    Fabrizio Benedetti
    Department of Neuroscience, University of Turin Medical School, 10125 Turin, Italy
    J Neurosci 25:10390-402. 2005
  24. ncbi request reprint Persistent auditory hallucinations that are unresponsive to antipsychotic drugs
    Stephen E Nicolson
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, USA
    Am J Psychiatry 163:1153-9. 2006
  25. ncbi request reprint Posttraumatic stress disorder: a state-of-the-science review
    Charles B Nemeroff
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322 4990, USA
    J Psychiatr Res 40:1-21. 2006
    ....
  26. ncbi request reprint Is late-life depression a predictor of Alzheimer's disease? Results from a historical cohort study
    Robert van Reekum
    Int J Geriatr Psychiatry 20:80-2. 2005
  27. pmc Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic
    Kerry J Ressler
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 954 Gatewood Drive, Atlanta, Georgia 30329, USA
    Nat Neurosci 10:1116-24. 2007
    ..Although many of these approaches are experimental, the rapidly developing understanding of emotional circuit regulation is likely to provide exciting and powerful future treatments for debilitating mood and anxiety disorders...
  28. doi request reprint Neuropsychological impact of Cg25 deep brain stimulation for treatment-resistant depression: preliminary results over 12 months
    Heather E McNeely
    Schizophrenia Services, Neuropsychology Service, St Joseph s Healthcare, Hamilton, Ontario, Canada
    J Nerv Ment Dis 196:405-10. 2008
    ..Though the sample size is small, these results support cognitive safety of Cg25 DBS for TRD...
  29. ncbi request reprint State and trait influences on mood regulation in bipolar disorder: blood flow differences with an acute mood challenge
    Stephanie Krüger
    Department of Psychiatry SK, University of Dresden, Dresden, Germany
    Biol Psychiatry 54:1274-83. 2003
    ..Imitating such stressors by the controlled transient exposure to an emotional stimulus may help to identify brain regions modulating this sensitivity...
  30. ncbi request reprint Unmasking disease-specific cerebral blood flow abnormalities: mood challenge in patients with remitted unipolar depression
    Mario Liotti
    Division of Psychiatry, Faculty of Medicine, University of Nottingham, A Floor, South Block, Queens Medical Centre, Nottingham NG7 2UH, UK
    Am J Psychiatry 159:1830-40. 2002
    ....
  31. ncbi request reprint Defining the neural circuitry of depression: toward a new nosology with therapeutic implications
    Helen S Mayberg
    Biol Psychiatry 61:729-30. 2007