Gilles A Robichaud
Leblanc N, Harquail J, Crapoulet N, Ouellette R, Robichaud G. Pax-5 Inhibits Breast Cancer Proliferation Through MiR-215 Up-regulation. Anticancer Res. 2018;38:5013-5026 pubmed publisher
..Pax-5 reduces breast cancer proliferation and migration through up-regulation of the tumor suppressor miR-215. This result supports the use of miR-215 as a prognostic marker for breast cancer. ..
Harquail J, Leblanc N, Landry C, Crapoulet N, Robichaud G. Pax-5 Inhibits NF-?B Activity in Breast Cancer Cells Through IKK? and miRNA-155 Effectors. J Mammary Gland Biol Neoplasia. 2018;23:177-187 pubmed publisher
..Further insight into the regulatory pathways of breast cancer progression will eventually identify strategic therapeutic and prognostic targets to improve cancer patient outcome. ..
Benzina S, Harquail J, Jean S, Beauregard A, Colquhoun C, Carroll M, et al
. Deoxypodophyllotoxin isolated from Juniperus communis induces apoptosis in breast cancer cells. Anticancer Agents Med Chem. 2015;15:79-88 pubmed
Beauregard A, Harquail J, Lassalle Claux G, Belbraouet M, Jean Francois J, Touaibia M, et al
. CAPE Analogs Induce Growth Arrest and Apoptosis in Breast Cancer Cells. Molecules. 2015;20:12576-89 pubmed publisher
..These CAPE analogs could thus provide new therapeutic approaches for patients with varying genotypic signatures (such as p53 mutations) in a more specific and targeted fashion. ..