Guang Yong Zou

Summary

Affiliation: Robarts Research Institute
Country: Canada

Publications

  1. ncbi A simple alternative confidence interval for the difference between two proportions
    Guangyong Zou
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada N6A 5K8
    Control Clin Trials 25:3-12. 2004
  2. ncbi Confidence interval estimation of the intraclass correlation coefficient for binary outcome data
    Guangyong Zou
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario N6A 5K8, Canada
    Biometrics 60:807-11. 2004
  3. ncbi Sample size formulas for estimating intraclass correlation coefficients with precision and assurance
    G Y Zou
    Department of Epidemiology and Biostatistics and Robarts Clinical Trials of Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada
    Stat Med 31:3972-81. 2012
  4. ncbi On the estimation of additive interaction by use of the four-by-two table and beyond
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Am J Epidemiol 168:212-24. 2008
  5. ncbi Toward using confidence intervals to compare correlations
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Psychol Methods 12:399-413. 2007
  6. ncbi Construction of confidence limits about effect measures: a general approach
    G Y Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ont, Canada N6A 5C1
    Stat Med 27:1693-702. 2008
  7. ncbi One relative risk versus two odds ratios: implications for meta-analyses involving paired and unpaired binary data
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Clin Trials 4:25-31. 2007
  8. ncbi The merits of testing Hardy-Weinberg equilibrium in the analysis of unmatched case-control data: a cautionary note
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Ann Hum Genet 70:923-33. 2006
  9. ncbi Statistical methods for the analysis of genetic association studies
    G Y Zou
    Robarts Clinical Trials, Robarts Research Institute, PO Box 5015, 100 Perth Drive, London, Ontario, Canada N6A 5K8
    Ann Hum Genet 70:262-76. 2006
  10. ncbi Group sequential methods for cluster randomization trials with binary outcomes
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Clin Trials 2:479-87. 2005

Detail Information

Publications31

  1. ncbi A simple alternative confidence interval for the difference between two proportions
    Guangyong Zou
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada N6A 5K8
    Control Clin Trials 25:3-12. 2004
    ..The results of an exact evaluation study show that this new procedure performs as well as Newcombe's procedure in terms of percent coverage and expected confidence interval width. Several examples are presented...
  2. ncbi Confidence interval estimation of the intraclass correlation coefficient for binary outcome data
    Guangyong Zou
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario N6A 5K8, Canada
    Biometrics 60:807-11. 2004
    ..Simulation results indicate that confidence intervals based on the estimator proposed by Fleiss and Cuzick provide coverage levels close to nominal over a wide range of parameter combinations. Two examples are presented...
  3. ncbi Sample size formulas for estimating intraclass correlation coefficients with precision and assurance
    G Y Zou
    Department of Epidemiology and Biostatistics and Robarts Clinical Trials of Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada
    Stat Med 31:3972-81. 2012
    ..In this paper, we present a method that explicitly incorporates a prespecified probability of achieving the prespecified width or lower limit of a confidence interval. The resultant closed-form formulas are shown to be very accurate...
  4. ncbi On the estimation of additive interaction by use of the four-by-two table and beyond
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Am J Epidemiol 168:212-24. 2008
    ..The approach is illustrated with three examples. A Microsoft Excel spreadsheet and SAS codes for the calculations are available from the author and the Journal's website, respectively...
  5. ncbi Toward using confidence intervals to compare correlations
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Psychol Methods 12:399-413. 2007
    ..These closed-form procedures are shown by simulation studies to provide very satisfactory results in small to moderate sample sizes. The proposed approach is illustrated with worked examples...
  6. ncbi Construction of confidence limits about effect measures: a general approach
    G Y Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ont, Canada N6A 5C1
    Stat Med 27:1693-702. 2008
    ..Numerical evaluation shows that this closed-form procedure outperforms existing methods, including the bootstrap...
  7. ncbi One relative risk versus two odds ratios: implications for meta-analyses involving paired and unpaired binary data
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Clin Trials 4:25-31. 2007
    ..Although statistically sound, both approaches result in overall odds ratios which are known to be less meaningful to consumers...
  8. ncbi The merits of testing Hardy-Weinberg equilibrium in the analysis of unmatched case-control data: a cautionary note
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Ann Hum Genet 70:923-33. 2006
    ..Examples from previous reports are used to illustrate the methodology...
  9. ncbi Statistical methods for the analysis of genetic association studies
    G Y Zou
    Robarts Clinical Trials, Robarts Research Institute, PO Box 5015, 100 Perth Drive, London, Ontario, Canada N6A 5K8
    Ann Hum Genet 70:262-76. 2006
    ..As a regression model in general, this approach may also be applied to incorporate covariates. Numerical examples implemented with standard software are presented...
  10. ncbi Group sequential methods for cluster randomization trials with binary outcomes
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Clin Trials 2:479-87. 2005
    ....
  11. ncbi A non-iterative confidence interval estimating procedure for the intraclass kappa statistic with multinomial outcomes
    Guangyong Zou
    Robarts Clinical Trials, Robarts Research Institute, 100 Perth Drive, London, Ontario, Canada N6A 5K8
    Biom J 47:682-90. 2005
    ..The procedure is illustrated with two examples from previously published medical studies...
  12. ncbi A modified poisson regression approach to prospective studies with binary data
    Guangyong Zou
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada
    Am J Epidemiol 159:702-6. 2004
    ..Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets...
  13. ncbi From diagnostic accuracy to accurate diagnosis: interpreting a test result with confidence
    Guangyong Zou
    Robarts Research Institute and the Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada
    Med Decis Making 24:313-8. 2004
    ..For small sample sizes, CI estimation for predictive values based on the classical logit transformation has been found to be very conservative. A method based on computer simulation has therefore been suggested as an alternative...
  14. ncbi Assessment of risks by predicting counterfactuals
    G Y Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ont, Canada N6A5C1
    Stat Med 28:3761-81. 2009
    ..Two examples are used to illustrate the methods...
  15. ncbi Quantifying responsiveness of quality of life measures without an external criterion
    Guang Yong Zou
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada
    Qual Life Res 14:1545-52. 2005
    ..Simple confidence interval procedures are provided and evaluated. We also discuss the possibility of applying the results to the analysis of data from a two independent groups pre-/post- design. Two examples are provided...
  16. ncbi A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
    Robert A Hegele
    Vascular Biology Research Group, Robarts Research Institute and Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada
    Hum Mol Genet 18:4189-94. 2009
    ....
  17. ncbi STrengthening the REporting of Genetic Association Studies (STREGA)--an extension of the STROBE statement
    Julian Little
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Genet Epidemiol 33:581-98. 2009
    ..The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct, or analysis...
  18. ncbi Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement
    Julian Little
    Canada Research Chair in Human Genome Epidemiology, Toronto, ON, Canada
    Eur J Epidemiol 24:37-55. 2009
    ..The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct, or analysis...
  19. ncbi Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement
    Julian Little
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Clin Epidemiol 62:597-608.e4. 2009
    ..The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed, but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct, or analysis...
  20. ncbi STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement
    Julian Little
    Canada Research Chair in Human Genome Epidemiology, University of Ottawa, Ottawa, Ontario, Canada
    PLoS Med 6:e22. 2009
    ..The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct, or analysis...
  21. ncbi STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement
    Julian Little
    University of Ottawa, Ottawa, Ontario, Canada
    Ann Intern Med 150:206-15. 2009
    ..The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct, or analysis...
  22. ncbi Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials
    Brian G Feagan
    Robarts Clinical Trials, Robarts Research Institute, University of Western Ontario, 100 Perth Dr, London, ON, Canada N6A 5K8
    JAMA 299:1690-7. 2008
    ..Maintenance therapy for Crohn disease features the use of immunosuppressive drugs, which are associated with an increased risk of infection. Identification of safe and effective maintenance strategies is a priority...
  23. ncbi The Phone-FITT: a brief physical activity interview for older adults
    Dawn P Gill
    Dept of Epidemiology and Biostatistics, University of Western Ontario, London, ON, Canada
    J Aging Phys Act 16:292-315. 2008
    ..29 (-.53 to -.01) to -.45 (-.68 to -.14). This study contributes preliminary evidence of the reliability and validity of the Phone-FITT...
  24. ncbi Interval estimation for a difference between intraclass kappa statistics
    Allan Donner
    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada
    Biometrics 58:209-15. 2002
    ..Sample size requirements that achieve a prespecified expected width for a confidence interval about a difference of kappa statistic are also presented...
  25. ncbi Polygenic determinants of severe hypertriglyceridemia
    Jian Wang
    Vascular Biology Research Group 2 Clinical Trials Group, Robarts Research Institute and Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Hum Mol Genet 17:2894-9. 2008
    ..At the extremes of a quantitative trait, such as severe HTG, are found the cumulative contributions of both multiple rare alleles with large genetic effects and common alleles with small effects...
  26. ncbi Comparison of regression models for the analysis of fall risk factors in older veterans
    Dawn P Gill
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada
    Ann Epidemiol 19:523-30. 2009
    ..To compare the performance of eight regression models for analyzing risk of falling, focusing on the effect of physical inactivity in older veterans...
  27. ncbi Methods for the statistical analysis of binary data in split-cluster designs
    Allan Donner
    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario N6A 5C1, Canada
    Biometrics 60:919-25. 2004
    ....
  28. ncbi STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement
    Julian Little
    Canada Research Chair in Human Genome Epidemiology, Ottawa, ON, Canada
    Eur J Clin Invest 39:247-66. 2009
    ..The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed, but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct or analysis...
  29. ncbi Assessing severity of epilepsy in children: preliminary evidence of validity and reliability of a single-item scale
    Kathy N Speechley
    University of Western Ontario, London, ON, Canada
    Epilepsy Behav 13:337-42. 2008
    ..91, 0.98) for test-retest reliability for each of two raters. These promising initial results support continuation of the multistage process of testing the validity and reliability of the GASE Scale within various clinical contexts...
  30. ncbi A cluster-randomized controlled trial of a blood conservation algorithm in patients undergoing total hip joint arthroplasty
    Cindy J Wong
    Robarts Research Institute, Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada
    Transfusion 47:832-41. 2007
    ..The optimum strategy for reducing allogeneic blood transfusion in patients undergoing total hip joint arthroplasty (THJA) is unknown...
  31. ncbi [The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies]
    Erik von Elm
    Institute of Social and Preventive Medicine ISPM, University of Bern, Berna, Suiza
    Rev Esp Salud Publica 82:251-9. 2008
    ..We hope that the STROBE statement will contribute to improving the quality of reporting of observational studies...