John W D McDonald

Summary

Affiliation: Robarts Research Institute
Country: Canada

Publications

  1. doi request reprint Methotrexate for induction of remission in refractory Crohn's disease
    John W D McDonald
    Robarts Clinical Trials, Robarts Research Institute, London, Canada
    Cochrane Database Syst Rev 12:CD003459. 2012
  2. ncbi request reprint Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease
    Brian G Feagan
    Robarts Clinical Trials, Western University, London, Ontario, Canada Department of Medicine, Western University, London, Ontario, Canada Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada Electronic address
    Gastroenterology 146:681-688.e1. 2014
  3. doi request reprint The role of centralized reading of endoscopy in a randomized controlled trial of mesalamine for ulcerative colitis
    Brian G Feagan
    Robarts Clinical Trials, Western University, London, Ontario, Canada
    Gastroenterology 145:149-157.e2. 2013
  4. ncbi request reprint Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin
    Brian G Feagan
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada
    Clin Gastroenterol Hepatol 6:1370-7. 2008
  5. ncbi request reprint Unfractionated or low molecular weight heparin for induction of remission in ulcerative colitis: a Cochrane inflammatory bowel disease and functional bowel disorders systematic review of randomized trials
    Nilesh Chande
    Gastroenterology, University of Western Ontario, London, Ontario, Canada
    Inflamm Bowel Dis 17:1979-86. 2011
  6. doi request reprint Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized trials
    Nilesh Chande
    Division of Gastroenterology, London Health Sciences Centre, The University of Western Ontario, South Street Hospital, 375 South St, London, Ontario, Canada
    Am J Gastroenterol 104:235-41; quiz 234, 242. 2009
  7. doi request reprint Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials
    Brian G Feagan
    Robarts Clinical Trials, Robarts Research Institute, University of Western Ontario, 100 Perth Dr, London, ON, Canada N6A 5K8
    JAMA 299:1690-7. 2008

Collaborators

  • Pierre Pare
  • William J Sandborn
  • Nilesh Chande
  • Severine Vermeire
  • Xavier Hebuterne
  • Alaa Rostom
  • Simon Bar-Meir
  • Pia Munkholm
  • Sandro Ardizzone
  • Brian G Feagan
  • Margaret K Vandervoort
  • Cindy J Wong
  • Allan Donner
  • Albert Cohen
  • Remo Panaccione
  • Guangyong Zou
  • Gordon R Greenberg
  • Chrystian Dallaire
  • Alain Bitton
  • Richard N Fedorak
  • Terry P Ponich
  • Ulrich Mittmann
  • Geert D'Haens
  • Denise Gilgen
  • Paul Rutgeerts
  • Raymond Bourdages
  • Frank Anderson
  • Charles N Bernstein
  • Donald G Macintosh
  • Fred Saibil
  • Robert A Enns
  • Marybeth Hopkins
  • Barrett G Levesque
  • Debra King
  • Lisa M Shackelton
  • Marianne Fahmy
  • Sigrid Nelson
  • Edward V Loftus
  • Gert A Van Assche
  • Suresh Pola
  • Simon P Travis
  • Gary Wild
  • Gediminas Kiudelis
  • Guang Yong Zou
  • Yaron Niv
  • Olga Alexeeva
  • Johannes Spleiss
  • Steven B Landau
  • Pavel Klvana
  • Asit Parikh
  • Jeffrey Baker
  • Marc Bradette
  • Réjean Dubé

Detail Information

Publications7

  1. doi request reprint Methotrexate for induction of remission in refractory Crohn's disease
    John W D McDonald
    Robarts Clinical Trials, Robarts Research Institute, London, Canada
    Cochrane Database Syst Rev 12:CD003459. 2012
    ..This systematic review is an update of a previously published Cochrane review...
  2. ncbi request reprint Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease
    Brian G Feagan
    Robarts Clinical Trials, Western University, London, Ontario, Canada Department of Medicine, Western University, London, Ontario, Canada Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada Electronic address
    Gastroenterology 146:681-688.e1. 2014
    ..Methotrexate and infliximab are effective therapies for Crohn's disease (CD). In the combination of maintenance methotrexate-infliximab trial, we evaluated the potential superiority of combination therapy over infliximab alone...
  3. doi request reprint The role of centralized reading of endoscopy in a randomized controlled trial of mesalamine for ulcerative colitis
    Brian G Feagan
    Robarts Clinical Trials, Western University, London, Ontario, Canada
    Gastroenterology 145:149-157.e2. 2013
    ..Interobserver differences in endoscopic assessments contribute to variations in rates of response to placebo in ulcerative colitis (UC) trials. We investigated whether centralized review of images could reduce these variations...
  4. ncbi request reprint Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin
    Brian G Feagan
    Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada
    Clin Gastroenterol Hepatol 6:1370-7. 2008
    ..This randomized, double-blind, controlled trial assessed the efficacy and safety of MLN0002, a monoclonal antibody targeting the alpha4beta7 integrin, in patients with active Crohn's disease...
  5. ncbi request reprint Unfractionated or low molecular weight heparin for induction of remission in ulcerative colitis: a Cochrane inflammatory bowel disease and functional bowel disorders systematic review of randomized trials
    Nilesh Chande
    Gastroenterology, University of Western Ontario, London, Ontario, Canada
    Inflamm Bowel Dis 17:1979-86. 2011
    ..We aimed to systematically review the efficacy of unfractionated heparin (UFH) or low molecular weight heparins (LMWH) for remission induction in patients with ulcerative colitis (UC)...
  6. doi request reprint Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized trials
    Nilesh Chande
    Division of Gastroenterology, London Health Sciences Centre, The University of Western Ontario, South Street Hospital, 375 South St, London, Ontario, Canada
    Am J Gastroenterol 104:235-41; quiz 234, 242. 2009
    ..To conduct a systematic review to determine effective treatments for patients with collagenous colitis or lymphocytic colitis, the two subtypes of microscopic colitis...
  7. doi request reprint Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials
    Brian G Feagan
    Robarts Clinical Trials, Robarts Research Institute, University of Western Ontario, 100 Perth Dr, London, ON, Canada N6A 5K8
    JAMA 299:1690-7. 2008
    ..Maintenance therapy for Crohn disease features the use of immunosuppressive drugs, which are associated with an increased risk of infection. Identification of safe and effective maintenance strategies is a priority...