Research Topics
| Jolie RingashSummaryCountry: Canada Publications
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Publications
Interpreting clinically significant changes in patient-reported outcomesJolie Ringash
Department of Radiation Oncology, Princess Margaret Hospital and University of Toronto, Toronto, Ontario, Canada
Cancer 110:196-202. 2007....- Postradiotherapy quality of life for head-and-neck cancer patients is independent of xerostomiaJolie Ringash
Department of Radiation Oncology, Princess Margaret Hospital and University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 61:1403-7. 2005..To determine the relationship between quality of life (QOL) and xerostomia over time for patients undergoing radiotherapy (RT) for head-and-neck cancer in a prospective clinical trial... 
Patterns of care in elderly head-and-neck cancer radiation oncology patients: a single-center cohort studyShao Hui Huang
Princess Margaret Hospital, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 79:46-51. 2011..To compare the patterns of care for elderly head-and-neck cancer patients with those of younger patients...- Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapyShao Hui Huang
Department of Radiation Oncology, Princess Margaret Hospital University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 82:276-83. 2012..To report atypical clinical behavior observed in human papillomavirus (HPV)-related oropharyngeal carcinoma (OPC) treated with radiotherapy... - Effect of concurrent high-dose cisplatin chemotherapy and conformal radiotherapy on cervical esophageal cancer survivalShao Hui Huang
Radiation Medicine Program, Princess Margaret Hospital, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 71:735-40. 2008..To determine whether a change in treatment policy to conformal, elective nodal radiotherapy and concurrent high-dose cisplatin improved survival for cervical esophageal cancer patients... - A dose escalation study of hyperfractionated accelerated radiation delivered with integrated neck surgery (HARDWINS) for the management of advanced head and neck cancerJohn Waldron
Department of Radiation Oncology, Princess Margaret Hospital and the University of Toronto, Canada
Radiother Oncol 87:173-80. 2008..To determine toxicity and outcome of radiation dose escalation with hyperfractionated accelerated radiation delivered with neck surgery (HARDWINS) for head and neck cancer... - Hyperfractionated, accelerated radiotherapy for locally advanced head and neck cancer: quality of life in a prospective phase I/II trialJolie Ringash
Department of Radiation Oncology, The Princess Margaret Hospital, Toronto, Canada
Radiother Oncol 87:181-7. 2008..Quality of life (QOL) was measured prospectively in a dose escalation study of twice daily hyperfractionated, accelerated radiotherapy for locally advanced head and neck cancer (HNC)... - Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionationBrian O'Sullivan
Department of Radiation Oncology, Princess Margaret Hospital, Toronto, Canada
Radiother Oncol 103:49-56. 2012..To report outcome of HPV-related [HPV(+)] oropharyngeal cancer (OPC) managed predominantly by altered-fractionation radiotherapy-alone (RT-alone)... - Stage-specific effect of adjuvant therapy following gastric cancer resection: a population-based analysis of 4,041 patientsNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Ann Surg Oncol 15:500-7. 2008..Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population... - Cone-beam CT assessment of interfraction and intrafraction setup error of two head-and-neck cancer thermoplastic masksMichael Velec
Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 76:949-55. 2010..To prospectively compare setup error in standard thermoplastic masks and skin-sparing masks (SSMs) modified with low neck cutouts for head-and-neck intensity-modulated radiation therapy (IMRT) patients... - Retrospective study of palliative radiotherapy in newly diagnosed head and neck carcinomaChristiaan M Stevens
Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, and University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 81:958-63. 2011..To examine the patterns of care, outcomes, and prognostic factors for patients with head-and-neck cancer (HNC) treated with palliative radiotherapy (RT)... - A Phase III placebo-controlled trial of oral pilocarpine in patients undergoing radiotherapy for head-and-neck cancerPadraig Warde
Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, 610 University Avenue, 5th Floor, Toronto, Ontario M5G 2M9, Canada
Int J Radiat Oncol Biol Phys 54:9-13. 2002..To test the hypothesis that the use of oral pilocarpine during and after radiotherapy (RT) for head-and-neck cancer would reduce the symptoms of post-RT xerostomia... - Rectal motion in patients receiving preoperative radiotherapy for carcinoma of the rectumJames D Brierley
Department of Radiation Medicine, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 80:97-102. 2011..To assess the movement of rectum, mesorectum, and rectal primary during a course of preoperative chemoradiotherapy... - Truths and myths about radiotherapy for verrucous carcinoma of larynxShao Hui Huang
Radiation Medicine Program, Princess Margaret Hospital, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 73:1110-5. 2009..To address these concerns, we report our experience... - Phase I study of individualized stereotactic body radiotherapy of liver metastasesMark T Lee
Radiation Medicine Program, Department of Biostatistics and Medical Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
J Clin Oncol 27:1585-91. 2009..To report on the outcomes of a phase I study of stereotactic body radiotherapy (SBRT) for treatment of liver metastases... - Cognitive functioning after radiotherapy or chemoradiotherapy for head-and-neck cancerHui K Gan
Department of Medical Oncology, Princess Margaret Hospital, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 81:126-34. 2011..To perform a comprehensive cognitive function (CF) assessment in patients who were relapse free after curative intent radiotherapy (RT) or chemoradiotherapy for squamous cell carcinoma of the head and neck... - Conformal radiotherapy in the adjuvant treatment of gastric cancer: Review of 82 casesZahra Kassam
Department of Radiation Oncology, The Princess Margaret Hospital, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 65:713-9. 2006..CONCLUSION: Adjuvant CRT for gastric cancer, even with conformal RT, is associated with significant toxicity. Survival was comparable to that reported in the Intergroup 0116 study... - Interfraction and respiratory organ motion during conformal radiotherapy in gastric cancerBarbara Wysocka
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 77:53-9. 2010..To quantify the interfraction and breathing organ motion during adjuvant radiotherapy for gastric cancer and assess organ stability in different breathing states... - Phase 2 trial of preoperative irinotecan plus cisplatin and conformal radiotherapy, followed by surgery for esophageal cancerJennifer J Knox
Department of Medical Oncology, Princess Margaret and Toronto General Hospitals of the University Health Network, Toronto, Ontario, Canada
Cancer 116:4023-32. 2010..Newer regimens may impact these poor outcomes. This phase 2 trial assessed the feasibility and efficacy of induction chemoradiotherapy with cisplatin and irinotecan followed by esophagectomy... - Primary radical external beam radiotherapy of rectal adenocarcinoma: long term outcome of 271 patientsYongjin Wang
Department of Radiation Oncology, Princess Margaret Hospital, Toronto, Canada
Radiother Oncol 77:126-32. 2005..However in patients with fixed tumors in this study, the outcome is poor and treatment should be considered palliative. Severe radiation toxicity is infrequent with current schedules and techniques of radiotherapy... - Natural course of distant metastases following radiotherapy or chemoradiotherapy in HPV-related oropharyngeal cancerShao Hui Huang
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada
Oral Oncol 49:79-85. 2013..To describe the natural course of distant metastases (DMs) following radiotherapy (RT) or chemoradiotherapy (CRT) in HPV(+) oropharyngeal carcinoma (OPC)... - Lack of influence of intravenous contrast on head and neck IMRT dose distributionsDaniel Letourneau
Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Acta Oncol 47:90-4. 2008..Here, the effect of physiologic and non-physiologic extremes of i.v. contrast densities on intensity modulated radiotherapy (IMRT) plans for patients with head and neck cancer was investigated... - Outcome and toxicity of postoperative short course adjuvant radiation and chemotherapy following resection of adenocarcinoma of the rectumJames D Brierley
Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital Ontario Cancer Institute, University Health Network, Toronto Ontario, Canada
Acta Oncol 43:567-70. 2004..In view of the changes in surgical and pathological techniques in the last decade, further studies are required to determine the merits or otherwise of postoperative Short Course Adjuvant Radiation... - The development and validation of a quality-of-life questionnaire for head and neck cancer patients with enteral feeding tubes: the QOL-EFChristiaan Seimeon Michael Stevens
Department of Radiation Oncology Princess Margaret Hospital, University Health Network and University of Toronto, 610 University Ave, Toronto, Ontario, Canada, M5G 2M9
Support Care Cancer 19:1175-82. 2011..To develop a questionnaire that measures the impact of enteral feeding tubes (EFTs) on the quality of life (QOL) of head and neck cancer (HNC) patients.. - Preoperative radiation with concurrent chemotherapy for resectable rectal cancer: effect of dose escalation on pathologic complete response, local recurrence-free survival, disease-free survival, and overall survivalKirsty L Wiltshire
Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 64:709-16. 2006..The primary endpoints were acute toxicity and pathologic complete response rate (pCR). Secondary endpoints were local recurrence-free survival (LRFS), disease-free survival (DFS), and overall survival (OS)... - Point-of-care outcome assessment in the cancer clinic: audit of data qualityKaren Wong
Department of Radiation Oncology, The Princess Margaret Hospital and The University of Toronto, Toronto, Ontario, Canada M5G 2M9
Radiother Oncol 95:339-43. 2010..To assess the completeness and accuracy of stage and outcome data in the Anthology of Outcomes (AOs), a prospective point-of-care physician-collected electronic data system for patients at the Princess Margaret Hospital... - Comparative prognostic value of HPV16 E6 mRNA compared with in situ hybridization for human oropharyngeal squamous carcinomaWei Shi
Department of Radiation Oncology, Princess Margaret Hospital Ontario Cancer Institute, 610 University Ave, Toronto, Ontario, Canada, M5G 2M9
J Clin Oncol 27:6213-21. 2009..We compared a quantitative real-time polymerase chain reaction (qRT-PCR) assay for HPV16 mRNA to a DNA in situ hybridization (ISH) method, and evaluated their significance for overall (OS) and disease-free (DFS) survival... - Adjuvant therapy for resected gastric cancer--rapid, yet incomplete adoption following results of intergroup 0116 trialNatalie G Coburn
Department of Surgery, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 70:1073-80. 2008..This study examined the adoption of adjuvant treatment following the trial results and the factors associated with its use... - Esthesioneuroblastoma: The Princess Margaret Hospital experienceGideon Bachar
Department of Otolaryngology Head and Neck Surgery, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Head Neck 30:1607-14. 2008..Esthesioneuroblastoma is rare. The aim of the study was to review our experience and to evaluate the staging system and treatment that best correlates with the patient outcome... - Intraobserver and interobserver variability in GTV delineation on FDG-PET-CT images of head and neck cancersStephen L Breen
Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 68:763-70. 2007..To determine if the addition of fluorodeoxyglucose positron emission tomography (FDG-PET) data changes primary site gross tumor volumes (GTVs) in head and neck cancers... - Response rates for mailout survey-driven studies in patients with head and neck cancerDavid P Goldstein
Department of Otolaryngology Head and Neck Surgery, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Head Neck 32:1585-91. 2010..The objective of this paper is to summarize response rates in patients with head and neck cancer, and to provide recommendations surrounding methodology used to design and implement mailout survey questionnaires... - Development of a disease-specific quality-of-life questionnaire for anterior and central skull base pathology--the skull base inventoryJohn R de Almeida
Department of Otolaryngology Head and Neck Surgery, University of Toronto, Toronto, Canada
Laryngoscope 122:1933-42. 2012..Anterior and central skull base lesions and their surgical treatment (endoscopic or open approaches) can affect quality of life. A disease-specific instrument is needed to compare quality of life for different surgical approaches... - Interpreting differences in quality of life: the FACT-H&N in laryngeal cancer patientsJolie Ringash
Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada
Qual Life Res 13:725-33. 2004..Quality of life (QOL) scores can be difficult to interpret, because small statistically significant differences can be clinically unimportant. Our goal was to estimate the magnitude of difference in QOL that is noticeable to patients... - Tolerability of the Intergroup 0099 (INT 0099) regimen in locally advanced nasopharyngeal cancer with a focus on patients' nutritional statusMala Bahl
Department of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 60:1127-36. 2004..The prophylactic insertion of a feeding tube may facilitate therapy completion and weight recovery in some patients... - Error in the delivery of radiation therapy: results of a quality assurance reviewGrace Huang
Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 61:1590-5. 2005..The introduction of new technology can produce new ways for errors to occur, necessitating ongoing evaluation of RT errors for quality assurance. Modifications to processes of care can produce important reductions in error rates... - Dosimetric comparison of IMRT vs. 3D conformal radiotherapy in the treatment of cancer of the cervical esophagusLouis Fenkell
Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON, Canada
Radiother Oncol 89:287-91. 2008..Radiotherapy planning for cervical esophageal cancer is challenging. We compared IMRT and 3D conformal radiotherapy (CRT) with respect to conformality of target coverage and normal tissue sparing... - IMRT for adjuvant radiation in gastric cancer: a preferred plan?Jolie Ringash
Department of Radiation Oncology, Princess Margaret Hospital and University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 63:732-8. 2005..To assess the potential advantage of intensity-modulated radiotherapy (IMRT) over conformal planning for postoperative adjuvant radiotherapy in patients with gastric carcinoma... - Survey of computer use for health topics by patients with head and neck cancerJane Lea
Princess Margaret Hospital, University Health Network, 5th Floor, Department of Radiation Oncology, 610 University Ave, Toronto, Ontario, M5G 2M9 Canada
Head Neck 27:8-14. 2005..Individuals seem to either embrace technology or not. In this respect, patients with head and neck cancer are similar to, rather than unique from, other patients with cancer... - Upper abdominal malignancies: intensity-modulated radiation therapyMojgan Taremi
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada
Front Radiat Ther Oncol 40:272-88. 2007..Clinical experience with dose-escalated IMRT is limited, and IMRT should continue to be studied in clinical trials before it is routinely used for upper abdominal malignancies... - Results of radiotherapy for primary subglottic squamous cell carcinomaSonya Paisley
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 52:1245-50. 2002..CONCLUSION: These data support the use of primary RT in the treatment of patients with primary squamous cell carcinoma of the subglottis as an appropriate treatment approach providing an option for laryngeal conservation...