D C Rice

Summary

Country: Canada

Publications

  1. pmc Neurotoxicity of lead, methylmercury, and PCBs in relation to the Great Lakes
    D C Rice
    Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, Ontario
    Environ Health Perspect 103:71-87. 1995
  2. pmc Lessons for neurotoxicology from selected model compounds: SGOMSEC joint report
    D C Rice
    Banting Research Centre, Ottawa, Ontario, Canada
    Environ Health Perspect 104:205-15. 1996
  3. pmc Behavioral effects of lead: commonalities between experimental and epidemiologic data
    D C Rice
    Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, Ontario, Canada
    Environ Health Perspect 104:337-51. 1996
  4. ncbi Effect of postnatal exposure to a PCB mixture in monkeys on multiple fixed interval-fixed ratio performance
    D C Rice
    Toxicology Research Division, Health Canada, Ottawa, Ontario, Canada
    Neurotoxicol Teratol 19:429-34. 1997
  5. ncbi Lack of effect of methylmercury exposure from birth to adulthood on information processing speed in the monkey
    D C Rice
    Toxicology Research Division, Health Canada, Ottawa, Ontario, Canada
    Neurotoxicol Teratol 20:275-83. 1998
  6. ncbi Sperm chromatin structure is altered in cynomolgus monkeys with environmentally relevant blood lead levels
    W G Foster
    Environmental Health Directorate, Department of Health, Ottawa, Ontario, Canada
    Toxicol Ind Health 12:723-35. 1996
  7. ncbi Effects of postnatal exposure of monkeys to a PCB mixture on concurrent random interval-random interval and progressive ratio performance
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Food Directorate Health Protection Branch, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 21:47-58. 1999
  8. ncbi Effects of postnatal exposure of monkeys to a PCB mixture on spatial discrimination reversal and DRL performance
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 20:391-400. 1998
  9. ncbi Effects of exposure to 3,3',4,4',5-pentachlorobiphenyl (PCB 126) throughout gestation and lactation on behavior (concurrent random interval-random interval and progressive ratio performance) in rats
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Ottawa, Ontario, Canada
    Neurotoxicol Teratol 21:679-87. 1999
  10. ncbi Lack of effect of 3,3'4,4',5-pentachlorobiphenyl (PCB 126) throughout gestation and lactation on multiple fixed interval-fixed ratio and DRL performance in rats
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety and Bureau of Biostatistics and Computer Applications, Health Protection Branch, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 20:645-50. 1998

Collaborators

Detail Information

Publications15

  1. pmc Neurotoxicity of lead, methylmercury, and PCBs in relation to the Great Lakes
    D C Rice
    Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, Ontario
    Environ Health Perspect 103:71-87. 1995
    ..However, the fact that the present human body burden is in a range at which functional deficits are probable suggests that efforts should be made to eliminate point sources of lead contamination in the Great Lakes basin...
  2. pmc Lessons for neurotoxicology from selected model compounds: SGOMSEC joint report
    D C Rice
    Banting Research Centre, Ottawa, Ontario, Canada
    Environ Health Perspect 104:205-15. 1996
    ..It is unlikely that the use of advanced behavioral methodology would alleviate the apparent lack of sensitivity of the rodent model for many agents...
  3. pmc Behavioral effects of lead: commonalities between experimental and epidemiologic data
    D C Rice
    Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, Ontario, Canada
    Environ Health Perspect 104:337-51. 1996
    ..However, careful behavioral analysis was required from researchers in both fields for such understanding to emerge...
  4. ncbi Effect of postnatal exposure to a PCB mixture in monkeys on multiple fixed interval-fixed ratio performance
    D C Rice
    Toxicology Research Division, Health Canada, Ottawa, Ontario, Canada
    Neurotoxicol Teratol 19:429-34. 1997
    ....
  5. ncbi Lack of effect of methylmercury exposure from birth to adulthood on information processing speed in the monkey
    D C Rice
    Toxicology Research Division, Health Canada, Ottawa, Ontario, Canada
    Neurotoxicol Teratol 20:275-83. 1998
    ..There were no differences between groups on any aspect of the experiment. These data provide further evidence for absence of cognitive impairment in monkeys exposed developmentally to methylmercury...
  6. ncbi Sperm chromatin structure is altered in cynomolgus monkeys with environmentally relevant blood lead levels
    W G Foster
    Environmental Health Directorate, Department of Health, Ottawa, Ontario, Canada
    Toxicol Ind Health 12:723-35. 1996
    ..We conclude that chronic lead exposure alters sperm chromatin structure at blood lead levels relevant to the human population and in the absence of effects on endocrine function and traditional measures of semen quality...
  7. ncbi Effects of postnatal exposure of monkeys to a PCB mixture on concurrent random interval-random interval and progressive ratio performance
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Food Directorate Health Protection Branch, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 21:47-58. 1999
    ..These results extend previous studies in these monkeys on the characterization of PCB-induced behavioral deficits...
  8. ncbi Effects of postnatal exposure of monkeys to a PCB mixture on spatial discrimination reversal and DRL performance
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 20:391-400. 1998
    ....
  9. ncbi Effects of exposure to 3,3',4,4',5-pentachlorobiphenyl (PCB 126) throughout gestation and lactation on behavior (concurrent random interval-random interval and progressive ratio performance) in rats
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Ottawa, Ontario, Canada
    Neurotoxicol Teratol 21:679-87. 1999
    ..These data extend previous findings concerning the pattern of behavioral effects as a consequence of gestational and lactational exposure to a dioxin-like PCB congener...
  10. ncbi Lack of effect of 3,3'4,4',5-pentachlorobiphenyl (PCB 126) throughout gestation and lactation on multiple fixed interval-fixed ratio and DRL performance in rats
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety and Bureau of Biostatistics and Computer Applications, Health Protection Branch, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 20:645-50. 1998
    ..These data provide further evidence for absence of behavioral toxicity as a result of gestational and lactational exposure to a dioxin-like PCB congener...
  11. ncbi Comparison of visual function at adulthood and during aging in monkeys exposed to lead or methylmercury
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Protection Branch, Health Canada
    Neurotoxicology 20:767-84. 1999
    ..These results extend previous findings of evidence for delayed neurotoxicity in the somatosensory and auditory systems of these methylmercury-exposed groups...
  12. ncbi Age-related increase in auditory impairment in monkeys exposed in utero plus postnatally to methylmercury
    D C Rice
    Toxicology Research Division, Health Protection Branch, Health Canada, Ottawa, Canada
    Toxicol Sci 44:191-6. 1998
    ..This study also provides evidence for development or acceleration of impairment of auditory function during aging as a consequence of developmental methylmercury exposure...
  13. ncbi Effect of exposure to 3,3',4,4',5-pentachlorobiphenyl (PCB 126) throughout gestation and lactation on development and spatial delayed alternation performance in rats
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Protection Branch, Health Canada, Ottawa, Ontario
    Neurotoxicol Teratol 21:59-69. 1999
    ..These data provide further evidence for the lack of neurotoxicity of dioxin-like PCB congeners. However, assessment of performance on additional behavioral indices is required before definitive conclusions may be drawn...
  14. ncbi Issues in developmental neurotoxicology: interpretation and implications of the data
    D C Rice
    Toxicology Research Division, Bureau of Chemical Safety, Health Protection Branch, Health Canada
    Can J Public Health 89:S31-6, S34-40. 1998
    ..Such changes in the functional abilities of a significant proportion of a population have potentially serious consequences for society as well as for affected individuals...
  15. ncbi Chronic lead exposure effects in the cynomolgus monkey (Macaca fascicularis) testis
    W G Foster
    Reproductive Toxicology Section, Health Canada, Ottawa, Ontario, Canada
    Ultrastruct Pathol 22:63-71. 1998
    ..Results of this study on the primate, following extrapolation to humans, could influence further refining of the impact of environmental lead contamination concentrations vis-à-vis the health of children, adults, and aged human beings...