Research Topics
| Krishna KumarSummaryAffiliation: Regina General Hospital Country: Canada Publications
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Detail Information
Publications
Treatment of chronic pain with spinal cord stimulation versus alternative therapies: cost-effectiveness analysisKrishna Kumar
Department of Surgery, Regina General Hospital, University of Saskatchewan, Canada
Neurosurgery 51:106-15; discussion 115-6. 2002....
Spinal cord stimulation in treatment of chronic benign pain: challenges in treatment planning and present status, a 22-year experienceKrishna Kumar
Section of Neurosurgery, Department of Surgery, University of Saskatchewan, Regina General Hospital, Regina, Canada
Neurosurgery 58:481-96; discussion 481-96. 2006..Suggestions for treatment of low back pain with a predominant axial component are addressed. We analyzed the complications and proposed remedial measures to improve the effectiveness of this modality...
Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial)Andrea Manca
Centre for Health Economics, Alcuin A Block, University of York, York YO10 5DD, United Kingdom
Eur J Pain 12:1047-58. 2008..Chronic back and leg pain conditions result in patients' loss of function, reduced quality of life and increased costs to the society...
Use of intrathecal bupivacaine in refractory chronic nonmalignant painKrishna Kumar
Department of Neurosurgery, Regina General Hospital, University of Saskatchewan, Regina, Saskatchewan, Canada
Pain Med 10:819-28. 2009..To demonstrate the efficacy and safety of the addition of bupivacaine in restoring pain control and improving quality of life and activity level in patients with chronic nonmalignant pain refractory to intrathecal opioids...
Spinal cord stimulation is effective in management of complex regional pain syndrome I: fact or fictionKrishna Kumar
Section of Neurosurgery, Department of Surgery, Regina General Hospital, University of Saskatchewan, Regina, Saskatchewan, Canada
Neurosurgery 69:566-78; discussion 5578-80. 2011..Spinal cord stimulation (SCS) is effective in the treatment of CRPS I in the medium term but its long-term efficacy and ability to improve functional status remains controversial...
Recombinant tissue plasminogen activator in the treatment of intraventricular hemorrhage secondary to periventricular arteriovenous malformation before surgery: case reportKrishna Kumar
Department of Surgery, Section of Neurosurgery, Regina General Hospital, University of Saskatchewan, Regina, Saskatchewan, Canada
Neurosurgery 52:964-8; discussion 968-9. 2003....
Spinal epidural abscessKrishna Kumar
Division of Neurosurgery, Regina General Hospital, University of Saskatchewan, Regina SK, Canada
Neurocrit Care 2:245-51. 2005..The goal of this article is to identify various prognostic factors, the role of inflammatory markers, optimal management strategies, and the relationship between timing of intervention and outcome...
A comparative analysis of the results of vertebroplasty and kyphoplasty in osteoporotic vertebral compression fracturesKrishna Kumar
Department of Neurosurgery, Regina General Hospital, Regina, Saskatchewan, Canada
Neurosurgery 67:ons171-88; discussion ons188. 2010..The most common complication of osteoporosis is vertebral fractures, which occur more frequently than all other fractures (hip, wrist, and ankle)...
Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndromeKrishna Kumar
Department of Neurosurgery, Regina General Hospital, 1440 14th Avenue, Regina, Sask, Canada
Pain 132:179-88. 2007..In selected patients with FBSS, SCS provides better pain relief and improves health-related quality of life and functional capacity compared with CMM alone...
Complications of spinal cord stimulation, suggestions to improve outcome, and financial impactKrishna Kumar
Department of Surgery, Section of Neurosurgery, Regina General Hospital, Regina, Saskatchewan, Canada
J Neurosurg Spine 5:191-203. 2006..Understanding the mechanism of complications and reducing them can improve the overall success rate and the cost factor...
The effects of spinal cord stimulation in neuropathic pain are sustained: a 24-month follow-up of the prospective randomized controlled multicenter trial of the effectiveness of spinal cord stimulationKrishna Kumar
Department of Neurosurgery, Regina General Hospital, Regina, Canada
Neurosurgery 63:762-70; discussion 770. 2008....
Treatment of chronic pain by using intrathecal drug therapy compared with conventional pain therapies: a cost-effectiveness analysisKrishna Kumar
Department of Surgery, Section of Neurosurgery, Regina General Hospital, University of Saskatchewan, Regina, Saskatchewan, Canada
J Neurosurg 97:803-10. 2002..The influence of these treatments on the quality of life (QOL) was also analyzed...
Financial impact of spinal cord stimulation on the healthcare budget: a comparative analysis of costs in Canada and the United StatesKrishna Kumar
Department of Neurosurgery, University of Saskatchewan, Regina General Hospital, Regina, Saskatchewan, Canada
J Neurosurg Spine 10:564-73. 2009..The authors present a formula that, when applied, provides a realistic representation of the actual costs necessary to implant and maintain SCS systems in Canada and the US...
Vertebroplasty in osteoporotic spine fractures: a quality of life assessmentKrishna Kumar
Department of Surgery, Section of Neurosurgery, Regina General Hospital, University of Saskatchewan, Regina, SK, Canada
Can J Neurol Sci 32:487-95. 2005..592 (p = 0.0000003). All p-values were determined by the Willcoxin sign-ranked test. CONCLUSION: Vertebroplasty is a safe and efficacious procedure with a resulting improvement in pain and quality of life...
Cost effectiveness of intrathecal drug therapy in management of chronic nonmalignant painKrishna Kumar
Department of Neurosurgery, University of Saskatchewan, Regina General Hospital, Regina, SK, Canada
Clin J Pain 29:138-45. 2013..To evaluate the cost effectiveness of intrathecal drug therapy (IDT) compared with conventional medical management (CMM) for patients with refractory chronic noncancer pain...
An analysis of the components of pain, function, and health-related quality of life in patients with failed back surgery syndrome treated with spinal cord stimulation or conventional medical managementSam Eldabe
Department of Pain and Anaesthesia, James Cook University Hospital, Middlesbrough, Cleveland, UK Department of Neurosurgery, Regina General Hospital, Regina, Saskatchewan, Canada Neuromodulation Centre EHC Hospital, Morges, and Anaesthesia Service, CHUV, Lausanne, Vaud, Switzerland and Peninsula Medical School, Universities of Exeter and Plymouth, Devon, UK
Neuromodulation 13:201-9. 2010..Conclusions: Longer-term patient management and research must focus on these refractory FBSS patients with persisting poor function and HRQoL outcomes...
Symptomatic spinal arachnoid cysts: report of two cases with review of the literatureKrishna Kumar
Department of Surgery, Section of Neurosurgery, Regina General Hospital, University of Saskatchewan, Regina, Saskatchewan, Canada
Spine (Phila Pa 1976) 28:E25-9. 2003..Two unusual cases of intradural extramedullary noncommunicating arachnoid cysts are presented, with a review of literature...
Rechargeable spinal cord stimulation versus non-rechargeable system for patients with failed back surgery syndrome: a cost-consequences analysisJohn Hornberger
Cedar Associates LLC, Menlo Park, CA 94025, USA
Clin J Pain 24:244-52. 2008..The study objective is to estimate the average difference in lifetime costs between rechargeable and non-rechargeable pulse generators used in treatment with SCS for failed back surgery syndrome...
Survey of the practice of spinal cord stimulators and intrathecal analgesic delivery implants for management of pain in CanadaPhilip W H Peng
Department of Anesthesiology and Pain Management, Toronto Western Division, University Health Network, University of Toronto, Toronto, Ontario, Canada
Pain Res Manag 12:281-5. 2007..The present survey characterizes the practice of spinal cord stimulator (SCS) and intrathecal analgesic delivery pump (IADP) implantation for pain management in different centres across Canada...
Antimicrobial activity and protease stability of peptides containing fluorinated amino acidsHe Meng
Department of Chemistry, Tufts University, Medford, Massachusetts 02155, USA
J Am Chem Soc 129:15615-22. 2007..These results suggest that fluorination may be an effective strategy to increase the stability of biologically active peptides where proteolytic degradation limits therapeutic value...
