Shirya Rashid

Summary

Country: Canada

Publications

  1. doi request reprint Effect of obesity on high-density lipoprotein metabolism
    Shirya Rashid
    Department of Medicine, Division of Cardiology, McGill University, Royal Victoria Hospital, Room H7 13, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Obesity (Silver Spring) 15:2875-88. 2007
  2. pmc Should cholesterol-lowering medications be available in Canada without a prescription?
    Shirya Rashid
    Department of Cardiology, McGill University, Montreal, Quebec
    Can J Cardiol 23:189-93. 2007
  3. ncbi request reprint Thematic review series: patient-oriented research. What have we learned about HDL metabolism from kinetics studies in humans?
    Shirya Rashid
    Department of Cardiology, McGill University, Montreal, Canada
    J Lipid Res 47:1631-42. 2006
  4. ncbi request reprint Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Canada
    Arterioscler Thromb Vasc Biol 22:483-7. 2002
  5. ncbi request reprint Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines
    Larbi Krimbou
    Cardiovascular Genetics Laboratory, Cardiology Division, McGill University Health Centre Royal Victoria Hospital, Montreal, Quebec H3A 1A1, Canada
    J Lipid Res 46:1668-77. 2005
  6. pmc Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
    Shirya Rashid
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9046, USA
    Proc Natl Acad Sci U S A 102:5374-9. 2005
  7. ncbi request reprint Mechanisms of HDL lowering in insulin resistant, hypertriglyceridemic states: the combined effect of HDL triglyceride enrichment and elevated hepatic lipase activity
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Ontario, Canada
    Clin Biochem 36:421-9. 2003
  8. ncbi request reprint Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Canada
    Circulation 107:3066-72. 2003
  9. ncbi request reprint Effect of atorvastatin on high-density lipoprotein apolipoprotein A-I production and clearance in the New Zealand white rabbit
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Canada
    Circulation 106:2955-60. 2002
  10. pmc Statins and primary prevention: is all the evidence in?
    Shirya Rashid
    Can J Cardiol 24:301-3. 2008

Collaborators

Detail Information

Publications10

  1. doi request reprint Effect of obesity on high-density lipoprotein metabolism
    Shirya Rashid
    Department of Medicine, Division of Cardiology, McGill University, Royal Victoria Hospital, Room H7 13, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Obesity (Silver Spring) 15:2875-88. 2007
    ..Increased lipid transfer to HDL by lipoprotein lipase and reduced HDL clearance by hepatic triglyceride lipase as a result of endurance training are two important mechanisms for increases in HDL observed from exercise...
  2. pmc Should cholesterol-lowering medications be available in Canada without a prescription?
    Shirya Rashid
    Department of Cardiology, McGill University, Montreal, Quebec
    Can J Cardiol 23:189-93. 2007
    ..The advantages and disadvantages of OTC or BTC statin usage must therefore be carefully weighed before any potential introduction of OTC or BTC statins in Canada...
  3. ncbi request reprint Thematic review series: patient-oriented research. What have we learned about HDL metabolism from kinetics studies in humans?
    Shirya Rashid
    Department of Cardiology, McGill University, Montreal, Canada
    J Lipid Res 47:1631-42. 2006
    ..Here, we review the progress in our understanding of HDL metabolism derived from in vivo kinetics studies, focusing primarily on studies in humans but also reviewing key studies in animal models...
  4. ncbi request reprint Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Canada
    Arterioscler Thromb Vasc Biol 22:483-7. 2002
    ..These data further support the important interaction between HDL TG enrichment and HL action in the pathogenesis of HDL lowering in hypertriglyceridemic states...
  5. ncbi request reprint Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines
    Larbi Krimbou
    Cardiovascular Genetics Laboratory, Cardiology Division, McGill University Health Centre Royal Victoria Hospital, Montreal, Quebec H3A 1A1, Canada
    J Lipid Res 46:1668-77. 2005
    ..Thus, our study provides direct evidence for a new link between specific cell lines and the speciation of nascent HDL that occurs by both ABCA1-dependent and -independent pathways...
  6. pmc Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
    Shirya Rashid
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9046, USA
    Proc Natl Acad Sci U S A 102:5374-9. 2005
    ..These data demonstrate that PCSK9 regulates the amount of LDLR protein in liver and suggest that inhibitors of PCSK9 may act synergistically with statins to enhance LDLRs and reduce plasma cholesterol...
  7. ncbi request reprint Mechanisms of HDL lowering in insulin resistant, hypertriglyceridemic states: the combined effect of HDL triglyceride enrichment and elevated hepatic lipase activity
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Ontario, Canada
    Clin Biochem 36:421-9. 2003
    ..The present review focuses on these metabolic alterations in insulin resistant states and their important contributions to the reduction of HDL-c and HDL-apoA-I plasma concentrations...
  8. ncbi request reprint Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Canada
    Circulation 107:3066-72. 2003
    ..Here, we examined in the rabbit the interaction between in vivo HL lipolytic action and HDL TG enrichment on the subsequent metabolic clearance of HDL apoA-I...
  9. ncbi request reprint Effect of atorvastatin on high-density lipoprotein apolipoprotein A-I production and clearance in the New Zealand white rabbit
    Shirya Rashid
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Canada
    Circulation 106:2955-60. 2002
    ..We therefore studied the effect of atorvastatin on HDL apolipoprotein (apo) A-I production and clearance in normolipidemic male New Zealand White rabbits...
  10. pmc Statins and primary prevention: is all the evidence in?
    Shirya Rashid
    Can J Cardiol 24:301-3. 2008