Claudine Rancourt

Summary

Country: Canada

Publications

  1. pmc Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis
    Nadzeya Goncharenko-Khaider
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada
    Mol Cancer 11:84. 2012
  2. pmc Osteoprotegerin (OPG) protects ovarian cancer cells from TRAIL-induced apoptosis but does not contribute to malignant ascites-mediated attenuation of TRAIL-induced apoptosis
    Denis Lane
    Departement De Microbiologie et Infectiologie, Universite de Sherbrooke, 3001 12ième avenue Nord, Sherbrooke, J1H 5N4, Canada
    J Ovarian Res 5:34. 2012
  3. pmc Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors
    Jennifer A A Gubbels
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, USA
    Mol Cancer 5:50. 2006
  4. pmc MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
    Jennifer A A Gubbels
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI, USA
    Mol Cancer 9:11. 2010
  5. pmc Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes
    Jennifer A Belisle
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI, USA
    Mol Cancer 9:118. 2010
  6. pmc Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies
    Cara Ar Goodell
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    J Ovarian Res 2:8. 2009
  7. pmc The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer
    Denis Lane
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada
    J Ovarian Res 3:1. 2010
  8. pmc Prognostic significance of IL-6 and IL-8 ascites levels in ovarian cancer patients
    Denis Lane
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada
    BMC Cancer 11:210. 2011
  9. pmc Immunohistochemical profiling of benign, low malignant potential and low grade serous epithelial ovarian tumors
    Veronique Ouellet
    Centre de Recherche du Centre Hospitalier de l Université de Montréal Institut du cancer de Montréal, Montreal, Canada
    BMC Cancer 8:346. 2008

Detail Information

Publications9

  1. pmc Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis
    Nadzeya Goncharenko-Khaider
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada
    Mol Cancer 11:84. 2012
    ..However, the underlying molecular mechanisms responsible for ascites-induced drug resistance are not well characterized...
  2. pmc Osteoprotegerin (OPG) protects ovarian cancer cells from TRAIL-induced apoptosis but does not contribute to malignant ascites-mediated attenuation of TRAIL-induced apoptosis
    Denis Lane
    Departement De Microbiologie et Infectiologie, Universite de Sherbrooke, 3001 12ième avenue Nord, Sherbrooke, J1H 5N4, Canada
    J Ovarian Res 5:34. 2012
    ..abstract:..
  3. pmc Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors
    Jennifer A A Gubbels
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, USA
    Mol Cancer 5:50. 2006
    ..Here we have addressed this deficit and provide further evidence supporting the role of the MUC16-mesothelin interaction in facilitating cell-cell binding under conditions that mimic the peritoneal environment...
  4. pmc MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
    Jennifer A A Gubbels
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI, USA
    Mol Cancer 9:11. 2010
    ..Our results indicate that MUC16-mediated inhibition of immune synapse formation is an effective mechanism employed by ovarian tumors to evade immune recognition...
  5. pmc Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes
    Jennifer A Belisle
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, WI, USA
    Mol Cancer 9:118. 2010
    ..In a previous study we demonstrated that sMUC16 binds to specific subset of NK cells. Here, we identify the csMUC16/sMUC16 binding partner expressed on immune cells...
  6. pmc Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies
    Cara Ar Goodell
    Department of Obstetrics and Gynecology, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    J Ovarian Res 2:8. 2009
    ..The major objective of this study was to determine if the murine ovarian tumor cells, MOVCAR, express Muc16 and to characterize antibodies that recognize this mucin...
  7. pmc The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer
    Denis Lane
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada
    J Ovarian Res 3:1. 2010
    ..In this context, we recently showed that ovarian cancer ascites may protect tumor cells from TRAIL-induced apoptosis. In this study, we sought to determine whether the prosurvival effect of ascites affects disease-free intervals...
  8. pmc Prognostic significance of IL-6 and IL-8 ascites levels in ovarian cancer patients
    Denis Lane
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, J1H 5N4, Canada
    BMC Cancer 11:210. 2011
    ..Levels of the pro-inflammatory cytokines IL-6 and IL-8 are elevated in EOC ascites suggesting that they could play a role in tumor progression...
  9. pmc Immunohistochemical profiling of benign, low malignant potential and low grade serous epithelial ovarian tumors
    Veronique Ouellet
    Centre de Recherche du Centre Hospitalier de l Université de Montréal Institut du cancer de Montréal, Montreal, Canada
    BMC Cancer 8:346. 2008
    ..Although the molecular characteristics of serous BOV, LMP and low grade (LG) TOV tumors has been initiated, definitive immunohistochemical markers to distinguish between these tumor types have not been defined...