Elaine O Petrof

Summary

Affiliation: Queen's University
Country: Canada

Publications

  1. ncbi From stool transplants to next-generation microbiota therapeutics
    Elaine O Petrof
    Department of Medicine, Division of Infectious Diseases and Gastrointestinal Research Unit, Queens University and Kingston General Hospital, Kingston, Ontario, Canada Electronic address
    Gastroenterology 146:1573-82. 2014
  2. ncbi Microbial ecosystems therapeutics: a new paradigm in medicine?
    E O Petrof
    Department of Medicine, Division of Infectious Diseases GI Diseases Research Unit, Queen s University, Kingston General Hospital, 76 Stuart Street, Kingston, ON K7L 2V7, Canada
    Benef Microbes 4:53-65. 2013
  3. pmc Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function
    Elaine O Petrof
    Department of Medicine, GIDRU, Division of Infectious Diseases, Queen s University, Kingston, ON, Canada
    Inflamm Bowel Dis 15:1537-47. 2009
  4. doi Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement
    Vandana Gambhir
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunobiology 216:988-96. 2011
  5. doi Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum
    Rostyslav Zvanych
    Department of Biochemistry and Biomedical Sciences, Department of Chemistry and Chemical Biology, M G DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
    J Antibiot (Tokyo) 67:85-8. 2014
  6. doi Probiotics in the critically ill: a systematic review of the randomized trial evidence
    Elaine O Petrof
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 40:3290-302. 2012
  7. doi Cross, but not direct, presentation of cell-associated virus antigens by spleen macrophages is influenced by their differentiation state
    Attiya Alatery
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunol Cell Biol 88:3-12. 2010

Collaborators

Detail Information

Publications8

  1. ncbi From stool transplants to next-generation microbiota therapeutics
    Elaine O Petrof
    Department of Medicine, Division of Infectious Diseases and Gastrointestinal Research Unit, Queens University and Kingston General Hospital, Kingston, Ontario, Canada Electronic address
    Gastroenterology 146:1573-82. 2014
    ..We discuss 2 pathways in the development of this new therapeutic class: whole microbial communities separated from donor stool and an assembly of specific fecal microorganisms grown in vitro...
  2. ncbi Microbial ecosystems therapeutics: a new paradigm in medicine?
    E O Petrof
    Department of Medicine, Division of Infectious Diseases GI Diseases Research Unit, Queen s University, Kingston General Hospital, 76 Stuart Street, Kingston, ON K7L 2V7, Canada
    Benef Microbes 4:53-65. 2013
    ..More than simply a new probiotic treatment, this emerging paradigm in medicine may lead to novel strategies in treating and managing a wide variety of human diseases...
  3. pmc Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function
    Elaine O Petrof
    Department of Medicine, GIDRU, Division of Infectious Diseases, Queen s University, Kingston, ON, Canada
    Inflamm Bowel Dis 15:1537-47. 2009
    ..The purpose of this study was to determine whether normal commensal bacteria could inhibit inflammatory pathways important in intestinal inflammation...
  4. doi Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement
    Vandana Gambhir
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunobiology 216:988-96. 2011
    ..Consequently, engagement of VDR by 1,25-(OH)ā‚‚Dā‚ƒ can partially interfere with TLR-4-L-induced activation of pAPCs only when it occurs before TLR-4 stimulation...
  5. doi Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum
    Rostyslav Zvanych
    Department of Biochemistry and Biomedical Sciences, Department of Chemistry and Chemical Biology, M G DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
    J Antibiot (Tokyo) 67:85-8. 2014
    ..Administration of these compounds resulted in decreased production of pro-inflammatory cytokine interferon (IFN)-gamma, which is of noted importance in gastrointestinal immune homeostasis. ..
  6. doi Probiotics in the critically ill: a systematic review of the randomized trial evidence
    Elaine O Petrof
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 40:3290-302. 2012
    ..The purpose of this systematic review was to evaluate the effect of probiotics in critically ill patients on clinical outcomes...
  7. doi Cross, but not direct, presentation of cell-associated virus antigens by spleen macrophages is influenced by their differentiation state
    Attiya Alatery
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunol Cell Biol 88:3-12. 2010
    ..Accordingly, Sp-Mphi can have an important role in regulating T-cell responses through cross-presentation depending on their differentiation state...