Elaine O Petrof

Summary

Affiliation: Queen's University
Country: Canada

Publications

  1. pmc From stool transplants to next-generation microbiota therapeutics
    Elaine O Petrof
    Department of Medicine, Division of Infectious Diseases and Gastrointestinal Research Unit, Queens University and Kingston General Hospital, Kingston, Ontario, Canada Electronic address
    Gastroenterology 146:1573-82. 2014
  2. doi Microbial ecosystems therapeutics: a new paradigm in medicine?
    E O Petrof
    Department of Medicine, Division of Infectious Diseases GI Diseases Research Unit, Queen s University, Kingston General Hospital, 76 Stuart Street, Kingston, ON K7L 2V7, Canada
    Benef Microbes 4:53-65. 2013
  3. pmc Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function
    Elaine O Petrof
    Department of Medicine, GIDRU, Division of Infectious Diseases, Queen s University, Kingston, ON, Canada
    Inflamm Bowel Dis 15:1537-47. 2009
  4. doi Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement
    Vandana Gambhir
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunobiology 216:988-96. 2011
  5. doi Administration of defined microbiota is protective in a murine Salmonella infection model
    Sarah Lynn E Martz
    Dept Medicine, Gastrointestinal Diseases Research Unit, Queen s University, Kingston, ON, K7L 2V7, Canada
    Sci Rep 5:16094. 2015
  6. doi Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum
    Rostyslav Zvanych
    Department of Biochemistry and Biomedical Sciences, Department of Chemistry and Chemical Biology, M G DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
    J Antibiot (Tokyo) 67:85-8. 2014
  7. doi Probiotics in the critically ill: a systematic review of the randomized trial evidence
    Elaine O Petrof
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 40:3290-302. 2012
  8. doi Cross, but not direct, presentation of cell-associated virus antigens by spleen macrophages is influenced by their differentiation state
    Attiya Alatery
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunol Cell Biol 88:3-12. 2010

Collaborators

Detail Information

Publications9

  1. pmc From stool transplants to next-generation microbiota therapeutics
    Elaine O Petrof
    Department of Medicine, Division of Infectious Diseases and Gastrointestinal Research Unit, Queens University and Kingston General Hospital, Kingston, Ontario, Canada Electronic address
    Gastroenterology 146:1573-82. 2014
    ..We discuss 2 pathways in the development of this new therapeutic class: whole microbial communities separated from donor stool and an assembly of specific fecal microorganisms grown in vitro...
  2. doi Microbial ecosystems therapeutics: a new paradigm in medicine?
    E O Petrof
    Department of Medicine, Division of Infectious Diseases GI Diseases Research Unit, Queen s University, Kingston General Hospital, 76 Stuart Street, Kingston, ON K7L 2V7, Canada
    Benef Microbes 4:53-65. 2013
    ..More than simply a new probiotic treatment, this emerging paradigm in medicine may lead to novel strategies in treating and managing a wide variety of human diseases...
  3. pmc Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function
    Elaine O Petrof
    Department of Medicine, GIDRU, Division of Infectious Diseases, Queen s University, Kingston, ON, Canada
    Inflamm Bowel Dis 15:1537-47. 2009
    ..The purpose of this study was to determine whether normal commensal bacteria could inhibit inflammatory pathways important in intestinal inflammation...
  4. doi Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement
    Vandana Gambhir
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunobiology 216:988-96. 2011
    ..Consequently, engagement of VDR by 1,25-(OH)ā‚‚Dā‚ƒ can partially interfere with TLR-4-L-induced activation of pAPCs only when it occurs before TLR-4 stimulation...
  5. doi Administration of defined microbiota is protective in a murine Salmonella infection model
    Sarah Lynn E Martz
    Dept Medicine, Gastrointestinal Diseases Research Unit, Queen s University, Kingston, ON, K7L 2V7, Canada
    Sci Rep 5:16094. 2015
    ..typhimurium from gaining access to the systemic circulation. We conclude that MET-1 may be protective against enteric infections besides C. difficile infection. ..
  6. doi Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum
    Rostyslav Zvanych
    Department of Biochemistry and Biomedical Sciences, Department of Chemistry and Chemical Biology, M G DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
    J Antibiot (Tokyo) 67:85-8. 2014
    ..Administration of these compounds resulted in decreased production of pro-inflammatory cytokine interferon (IFN)-gamma, which is of noted importance in gastrointestinal immune homeostasis. ..
  7. doi Probiotics in the critically ill: a systematic review of the randomized trial evidence
    Elaine O Petrof
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 40:3290-302. 2012
    ..The purpose of this systematic review was to evaluate the effect of probiotics in critically ill patients on clinical outcomes...
  8. doi Cross, but not direct, presentation of cell-associated virus antigens by spleen macrophages is influenced by their differentiation state
    Attiya Alatery
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    Immunol Cell Biol 88:3-12. 2010
    ..Accordingly, Sp-Mphi can have an important role in regulating T-cell responses through cross-presentation depending on their differentiation state...