Christopher R Mueller

Summary

Affiliation: Queen's University
Country: Canada

Publications

  1. doi request reprint Expression microarray identifies the unliganded glucocorticoid receptor as a regulator of gene expression in mammary epithelial cells
    Heather D Ritter
    Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada K7L 3N6
    BMC Cancer 14:275. 2014
  2. doi request reprint The unliganded glucocorticoid receptor positively regulates the tumor suppressor gene BRCA1 through GABP beta
    Heather D Ritter
    Department of Biochemistry, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Mol Cancer Res 10:558-69. 2012
  3. pmc Stress and breast cancer: from epidemiology to molecular biology
    Lilia Antonova
    Center for Cancer Therapeutics, Ottawa Hospital Research Institute, 501 Smyth Rd, TOHCC 3rd floor, Ottawa, ON, K1H 8L6, Canada
    Breast Cancer Res 13:208. 2011
  4. doi request reprint Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: a possible molecular link between stress and breast cancer
    Lilia Antonova
    Queen s Cancer Research Institute, Queen s University, Kingston, ON, Canada
    Genes Chromosomes Cancer 47:341-52. 2008
  5. pmc Decreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1-containing complex
    Crista Thompson
    Pathology and Molecular Medicine Department, Queen s University, Kingston, Ontario, Canada
    Mol Cancer 10:62. 2011
  6. pmc A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells
    Michelle R Sam
    Department of Pathology and Molecular Medicine, Queen s University, Kingston, Canada
    Mol Cancer 6:69. 2007
  7. pmc Characterization of a negative transcriptional element in the BRCA1 promoter
    Gwen MacDonald
    Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada, K7L 3N6
    Breast Cancer Res 9:R49. 2007
  8. pmc Regulation of BRCA1 expression and its relationship to sporadic breast cancer
    Christopher R Mueller
    Cancer Research Laboratories, Queen s University, Kingston, Ontario, Canada
    Breast Cancer Res 5:45-52. 2003

Collaborators

Detail Information

Publications8

  1. doi request reprint Expression microarray identifies the unliganded glucocorticoid receptor as a regulator of gene expression in mammary epithelial cells
    Heather D Ritter
    Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada K7L 3N6
    BMC Cancer 14:275. 2014
    ..Our previous studies implicated unliganded GR as a positive regulator of the BRCA1 tumour suppressor gene in the absence of glucocorticoid hormone, which suggested it could play a similar role in the regulation of other genes...
  2. doi request reprint The unliganded glucocorticoid receptor positively regulates the tumor suppressor gene BRCA1 through GABP beta
    Heather D Ritter
    Department of Biochemistry, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Mol Cancer Res 10:558-69. 2012
    ..Because low levels of BRCA1 have been implicated in the development of sporadic breast cancer, this may represent a novel mechanism through which prolonged stress signaling increases breast cancer risk...
  3. pmc Stress and breast cancer: from epidemiology to molecular biology
    Lilia Antonova
    Center for Cancer Therapeutics, Ottawa Hospital Research Institute, 501 Smyth Rd, TOHCC 3rd floor, Ottawa, ON, K1H 8L6, Canada
    Breast Cancer Res 13:208. 2011
    ....
  4. doi request reprint Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: a possible molecular link between stress and breast cancer
    Lilia Antonova
    Queen s Cancer Research Institute, Queen s University, Kingston, ON, Canada
    Genes Chromosomes Cancer 47:341-52. 2008
    ....
  5. pmc Decreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1-containing complex
    Crista Thompson
    Pathology and Molecular Medicine Department, Queen s University, Kingston, Ontario, Canada
    Mol Cancer 10:62. 2011
    ..Thus, elucidating the regulatory mechanisms of BRCA1 expression is important to our understanding of normal and malignant breast differentiation...
  6. pmc A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells
    Michelle R Sam
    Department of Pathology and Molecular Medicine, Queen s University, Kingston, Canada
    Mol Cancer 6:69. 2007
    ..This could lead to paracrine or autocrine activation of the Met receptor in breast carcinoma cells...
  7. pmc Characterization of a negative transcriptional element in the BRCA1 promoter
    Gwen MacDonald
    Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada, K7L 3N6
    Breast Cancer Res 9:R49. 2007
    ....
  8. pmc Regulation of BRCA1 expression and its relationship to sporadic breast cancer
    Christopher R Mueller
    Cancer Research Laboratories, Queen s University, Kingston, Ontario, Canada
    Breast Cancer Res 5:45-52. 2003
    ....