Affiliation: Queen's University
- Partiton-controlled delivery of toxicants: a novel in vivo approach for embryo toxicity testingYiannis Kiparissis
School of Environmental Studies, Queen s University, Kingston, Ontario, Canada, K7L 3N6
Environ Sci Technol 37:2262-6. 2003..The PCD method is a more sensitive and realistic method for assessing toxicity of nonpolar compounds than (semi)-static assays...
- Effects of the isoflavones genistein and equol on the gonadal development of Japanese medaka Oryzias latipesYiannis Kiparissis
Environmental and Resource Studies, Trent University, Peterborough, Ontario, Canada
Environ Health Perspect 111:1158-63. 2003..This laboratory study indicates that isoflavone compounds should be considered candidate estrogenic compounds that may be involved in the alteration of sexual development in feral fish populations...
- Endocrine disruption and altered gonadal development in white perch (Morone americana) from the lower Great Lakes regionRichard J Kavanagh
Environmental and Resource Studies, Trent University, 1600 West Bank Drive, Peterborough, Ontario K9J 7B8, Canada
Environ Health Perspect 112:898-902. 2004..These observations indicate that male white perch are exposed to estrogenic endocrine-disrupting substances that may be responsible for the induction of gonadal intersex...
- Measuring the toxicity of alkyl-phenanthrenes to early life stages of medaka (Oryzias latipes) using partition-controlled deliveryDominique Turcotte
Queen s University, Kingston, Ontario, Canada
Environ Toxicol Chem 30:487-95. 2011..These results extend conclusions for the Exxon Valdez oil spill, suggest a specific mechanism of toxicity for alkyl-phenanthrenes, and provide a model for assessing the risks of mixture toxicity...
- Effects of the antiandrogens, vinclozolin and cyproterone acetate on gonadal development in the Japanese medaka (Oryzias latipes)Yiannis Kiparissis
Environmental and Resource Studies, Trent University, Peterborough, Ont, Canada K9J 7B8
Aquat Toxicol 63:391-403. 2003..The results of this study indicate that antiandrogens have the potential to alter testicular development and gametogenesis in fish. However, research is needed to determine the mechanisms by which antiandrogens affect fish...
- Increased cellular apoptosis after chronic aqueous exposure to nonylphenol and quercetin in adult medaka (Oryzias latipes)Lynn P Weber
Department of Zoology, Oklahoma State University, 430 Life Sciences West, Stillwater, OK 74078, USA
Comp Biochem Physiol C Toxicol Pharmacol 131:51-9. 2002..These results suggest that nonylphenol caused testicular degeneration via increased testicular cell apoptosis, while quercetin may be ovotoxic via increased follicular atresia...