Daren K Heyland

Summary

Affiliation: Queen's University
Country: Canada

Publications

  1. doi request reprint The Canadian critical care nutrition guidelines in 2013: an update on current recommendations and implementation strategies
    Rupinder Dhaliwal
    Daren K Heyland, MSc, Department of Public Health Sciences, Queen s University, 76 Stuart St, Kingston, ON K7L 2V7, Canada Email
    Nutr Clin Pract 29:29-43. 2014
  2. doi request reprint The development and validation of a shorter version of the Canadian Health Care Evaluation Project Questionnaire (CANHELP Lite): a novel tool to measure patient and family satisfaction with end-of-life care
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ontario, Canada
    J Pain Symptom Manage 46:289-97. 2013
  3. doi request reprint Failure to engage hospitalized elderly patients and their families in advance care planning
    Daren K Heyland
    Clinical Evaluation Research Unit, Department of Medicine, Kingston General Hospital, Angada 4, Kingston, ON K7L 2V7, Canada
    JAMA Intern Med 173:778-87. 2013
  4. ncbi request reprint A randomized trial of glutamine and antioxidants in critically ill patients
    Daren Heyland
    Kingston General Hospital, Kingston, ON, Canada
    N Engl J Med 368:1489-97. 2013
  5. doi request reprint Optimal amount of calories for critically ill patients: depends on how you slice the cake!
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario, Canada
    Crit Care Med 39:2619-26. 2011
  6. pmc Antioxidant micronutrients in the critically ill: a systematic review and meta-analysis
    William Manzanares
    Intensive Care Unit, Department of Critical Care Medicine, Universidad de Republica, Hospital de Clínicas University Hospital, Faculty of Medicine, Avda Italia s n 14th Floor, Montevideo, 11600, Uruguay
    Crit Care 16:R66. 2012
  7. pmc Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada
    Crit Care 15:R268. 2011
  8. doi request reprint The success of enteral nutrition and ICU-acquired infections: a multicenter observational study
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Queen s University, Angada 4, 76 Stuart Street, Kingston, Ontario, Canada
    Clin Nutr 30:148-55. 2011
  9. pmc Defining priorities for improving end-of-life care in Canada
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ont
    CMAJ 182:E747-52. 2010
  10. pmc Enhanced protein-energy provision via the enteral route in critically ill patients: a single center feasibility trial of the PEP uP protocol
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, ON, Canada
    Crit Care 14:R78. 2010

Detail Information

Publications84

  1. doi request reprint The Canadian critical care nutrition guidelines in 2013: an update on current recommendations and implementation strategies
    Rupinder Dhaliwal
    Daren K Heyland, MSc, Department of Public Health Sciences, Queen s University, 76 Stuart St, Kingston, ON K7L 2V7, Canada Email
    Nutr Clin Pract 29:29-43. 2014
    ..The active implementation of the updated CCPGs may lead to better nutrition care and improved patient outcomes in the critical care setting. ..
  2. doi request reprint The development and validation of a shorter version of the Canadian Health Care Evaluation Project Questionnaire (CANHELP Lite): a novel tool to measure patient and family satisfaction with end-of-life care
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ontario, Canada
    J Pain Symptom Manage 46:289-97. 2013
    ..The length of the interview may limit its uptake and clinical utility; a shorter version would make its use more feasible...
  3. doi request reprint Failure to engage hospitalized elderly patients and their families in advance care planning
    Daren K Heyland
    Clinical Evaluation Research Unit, Department of Medicine, Kingston General Hospital, Angada 4, Kingston, ON K7L 2V7, Canada
    JAMA Intern Med 173:778-87. 2013
    ..Advance care planning can improve patient-centered care and potentially reduce intensification of care at the end of life...
  4. ncbi request reprint A randomized trial of glutamine and antioxidants in critically ill patients
    Daren Heyland
    Kingston General Hospital, Kingston, ON, Canada
    N Engl J Med 368:1489-97. 2013
    ..Critically ill patients have considerable oxidative stress. Glutamine and antioxidant supplementation may offer therapeutic benefit, although current data are conflicting...
  5. doi request reprint Optimal amount of calories for critically ill patients: depends on how you slice the cake!
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario, Canada
    Crit Care Med 39:2619-26. 2011
    ..The optimal amount of calories required by critically ill patients continues to be controversial. The objective of this study is to examine the relationship between the amount of calories administered and mortality...
  6. pmc Antioxidant micronutrients in the critically ill: a systematic review and meta-analysis
    William Manzanares
    Intensive Care Unit, Department of Critical Care Medicine, Universidad de Republica, Hospital de Clínicas University Hospital, Faculty of Medicine, Avda Italia s n 14th Floor, Montevideo, 11600, Uruguay
    Crit Care 16:R66. 2012
    ..We hypothesized that exogenous supplementation of trace elements and vitamins could restore antioxidant status, improving clinical outcomes...
  7. pmc Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada
    Crit Care 15:R268. 2011
    ..To develop a scoring method for quantifying nutrition risk in the intensive care unit (ICU)...
  8. doi request reprint The success of enteral nutrition and ICU-acquired infections: a multicenter observational study
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Queen s University, Angada 4, 76 Stuart Street, Kingston, Ontario, Canada
    Clin Nutr 30:148-55. 2011
    ..The objective of this study was to evaluate the relationship between increasing success with enteral nutrition (EN) and acquired infection in the Intensive Care Unit (ICU)...
  9. pmc Defining priorities for improving end-of-life care in Canada
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ont
    CMAJ 182:E747-52. 2010
    ..The objective of this study was to identify aspects of end-of-life care that are high in priority as targets for improvement using feedback elicited from patients and their families...
  10. pmc Enhanced protein-energy provision via the enteral route in critically ill patients: a single center feasibility trial of the PEP uP protocol
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, ON, Canada
    Crit Care 14:R78. 2010
    ..The purpose of this pilot study is to assess the feasibility, acceptability, and safety of a new feeding protocol designed to enhance the delivery of enteral nutrition (EN)...
  11. ncbi request reprint Satisfaction with end-of-life care: a longitudinal study of patients and their family caregivers in the last months of life
    Daren K Heyland
    Clinical Evaluation Research Unit, Angada 4, Kingston General Hospital, 76 Stuart Street, Kingston, Ontario, Canada K7L 2V7
    J Palliat Care 25:245-56. 2009
    ..Satisfaction with care tends to vary based on location of interview and may vary across time with respect to certain aspects of EOL care...
  12. ncbi request reprint Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia
    Daren K Heyland
    Kingston General Hospital and Queen s University, Kingston, ON, Canada
    Crit Care Med 36:737-44. 2008
    ..To compare a strategy of combination therapy with a strategy of monotherapy with broad-spectrum antibiotics for suspected late ventilator-associated pneumonia...
  13. doi request reprint Zinc supplementation in critically ill patients: a key pharmaconutrient?
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 32:509-19. 2008
    ..Subsequently, large, rigorously designed, randomized trials are required to elucidate the efficacy of such doses of zinc supplementation in this patient population...
  14. doi request reprint The development and validation of a novel questionnaire to measure patient and family satisfaction with end-of-life care: the Canadian Health Care Evaluation Project (CANHELP) Questionnaire
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ontario, Canada
    Palliat Med 24:682-95. 2010
    ..We conclude that the CANHELP Questionnaire is a valid and internally consistent instrument to measure satisfaction with end-of-life care...
  15. doi request reprint Lost in (knowledge) translation!
    Daren K Heyland
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:610-5. 2010
    ....
  16. doi request reprint Creating a culture of clinical excellence in critical care nutrition: the 2008 "Best of the Best" award
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, ON, Canada
    JPEN J Parenter Enteral Nutr 34:707-15. 2010
    ..To develop, validate, and implement a system to reward top performers in critical care nutrition practice and to illuminate characteristics of top-performing intensive care units (ICUs)...
  17. doi request reprint Procalcitonin for reduced antibiotic exposure in the critical care setting: a systematic review and an economic evaluation
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 39:1792-9. 2011
    ..The purpose of this analysis was to evaluate the effect of a procalcitonin-guided antibiotic strategy on clinical and economic outcomes...
  18. doi request reprint Serum β-d-glucan of critically ill patients with suspected ventilator-associated pneumonia: preliminary observations
    Daren Heyland
    Department of Medicine, Queen s University, Kingston, ON, Canada
    J Crit Care 26:536.e1-9. 2011
    ..The purpose of this pilot study was to determine whether β-d-glucan (BG) was associated with Candida in the lung and risk of death in patients with suspected ventilator-associated pneumonia (VAP)...
  19. pmc Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials
    Daren K Heyland
    Department of Medicine, Queen s University, 76 Stuart Street, Kingston, ON K7L 2V7, Canada
    Crit Care 15:R98. 2011
    ..The objective of this study was to validate and demonstrate the utility of a novel composite outcome measure, persistent organ dysfunction (POD) plus death, for clinical trials of critically ill patients...
  20. pmc What matters most in end-of-life care: perceptions of seriously ill patients and their family members
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ont
    CMAJ 174:627-33. 2006
    ..The primary purpose of this study was to describe what seriously ill patients in hospital and their family members consider to be the key elements of quality end-of-life care...
  21. ncbi request reprint End-of-life care in acute care hospitals in Canada: a quality finish?
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Ontario, Canada
    J Palliat Care 21:142-50. 2005
    ..Improvement initiatives to target key elements identified by patients and FCGs have the potential to improve satisfaction with EOL care across care settings...
  22. doi request reprint Enhanced protein-energy provision via the enteral route feeding protocol in critically ill patients: results of a cluster randomized trial
    Daren K Heyland
    1Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada 2Department of Community Health and Epidemiology, Queen s University, Kingston, ON, Canada 3Department of Medicine, Queen s University, Kingston, ON, Canada 4Specialized Complex Care Program, St Michael s Hospital, Toronto, ON, Canada 5Department of Critical Care Medicine, Institute for Public Health, University of Calgary, Calgary, AB, Canada 6Department of Medicine, Institute for Public Health, University of Calgary, Calgary, AB, Canada 7Department of Community Health Sciences, Institute for Public Health, University of Calgary, Calgary, AB, Canada 8Department of Nursing, Mount Royal College, Calgary, Canada 9Department of Critical Care, Royal Alexandra Hospital, Edmonton, Alberta, Canada
    Crit Care Med 41:2743-53. 2013
    ..To determine the effect of the enhanced protein-energy provision via the enteral route feeding protocol, combined with a nursing educational intervention on nutritional intake, compared to usual care...
  23. ncbi request reprint REducing Deaths due to OXidative Stress (The REDOXS Study): Rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically-ill patients
    Daren K Heyland
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario K7L 2V7, Canada
    Proc Nutr Soc 65:250-63. 2006
    ..The trial will be conducted in approximately twenty tertiary-care ICU in Canada and the first results are expected in 2009...
  24. doi request reprint When early enteral feeding is not possible in critically ill patients: results of a multicenter observational study
    Naomi E Cahill
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 35:160-8. 2011
    ..When these situations arise, controversy exists whether to start feeding early via the parenteral route or to delay feeding until EN can be provided...
  25. ncbi request reprint Decision-making in the ICU: perspectives of the substitute decision-maker
    Daren K Heyland
    Department of Medicine, Angada 3, Kingston General Hospital, Ontario, Canada
    Intensive Care Med 29:75-82. 2003
    ..To describe the substitute decision-makers' perspectives related to decision-making in the intensive care unit (ICU) and to determine those variables associated with their overall satisfaction with decision-making...
  26. ncbi request reprint Understanding cardiopulmonary resuscitation decision making: perspectives of seriously ill hospitalized patients and family members
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, ON, Canada
    Chest 130:419-28. 2006
    ..To improve communication and decision making related to cardiopulmonary resuscitation (CPR), a greater understanding of the perspectives of hospitalized patients with advanced diseases and their family members are needed...
  27. ncbi request reprint Most critically ill patients are perceived to die in comfort during withdrawal of life support: a Canadian multicentre study
    Graeme M Rocker
    Department of Medicine, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada
    Can J Anaesth 51:623-30. 2004
    ..Most deaths in intensive care units (ICUs) follow a withdrawal of life support (LS). Evaluation of this process including the related perspectives of grieving family members is integral to improvement of palliation in the ICU...
  28. ncbi request reprint Validation of the Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients: results of a prospective observational study
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario
    Crit Care Med 32:2260-6. 2004
    ..To validate these guidelines, we hypothesized that intensive care units whose practice, on average, was more consistent with the guidelines would have greater success in providing enteral nutrition...
  29. ncbi request reprint Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 27:355-73. 2003
    ..This study was conducted to develop evidence-based clinical practice guidelines for nutrition support (ie, enteral and parenteral nutrition) in mechanically ventilated critically ill adults...
  30. doi request reprint Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: prevalence, incidence, risk factors, and outcomes
    Chris M Parker
    Department of Medicine, Queen s University, Kingston, Ontario, Canada K7L 2V7
    J Crit Care 23:18-26. 2008
    ....
  31. ncbi request reprint Nutrition and infection in the intensive care unit: what does the evidence show?
    Rupinder Dhaliwal
    Department of Medicine, Queen s University Kingston, Ontario, Canada
    Curr Opin Crit Care 11:461-7. 2005
    ..The newly published data will be used to update the Canadian Clinical Practice Guidelines...
  32. doi request reprint Nutrition therapy for the critically ill surgical patient: we need to do better!
    John W Drover
    Department of Surgery, Queen sUniversity, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:644-52. 2010
    ..To identify opportunities for quality improvement, the nutrition adequacy of critically ill surgical patients, in contrast to medical patients, is described...
  33. doi request reprint Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic review
    David W Frost
    Division of General Internal Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 39:1174-89. 2011
    ..DATA SOURCES, SELECTION, AND ABSTRACTION: We conducted a structured search of Ovid Medline for interventional and observational research articles incorporating critical care and end-of-life decision-making terms...
  34. doi request reprint The value of audit and feedback reports in improving nutrition therapy in the intensive care unit: a multicenter observational study
    Tasnim Sinuff
    Department of Critical Care Medicine, University of Toronto, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:660-8. 2010
    ..The objective of this study was to determine whether auditing practice and providing feedback in the form of benchmarked site reports is an effective strategy to improve adherence to nutrition guidelines...
  35. pmc Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia
    Marie Soleil Delisle
    Kingston General Hospital, Ontario
    Can Respir J 18:131-6. 2011
    ..The significance of Candida species in respiratory tract (RT) secretions in critically ill patients is unclear...
  36. doi request reprint Impact of enteral feeding protocols on enteral nutrition delivery: results of a multicenter observational study
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:675-84. 2010
    ..To evaluate the effect of enteral feeding protocols on key indicators of enteral nutrition in the critical care setting...
  37. doi request reprint Early use of supplemental parenteral nutrition in critically ill patients: results of an international multicenter observational study
    Jim Kutsogiannis
    Capital Health Authority, Edmonton, AB, Canada
    Crit Care Med 39:2691-9. 2011
    ..To evaluate the effect of using supplemental parenteral nutrition compared to early enteral nutrition alone on nutritional and clinical outcomes...
  38. doi request reprint Determinants of outcome in patients with a clinical suspicion of ventilator-associated pneumonia
    John G Muscedere
    Department of Medicine, Queen s University, Kingston, Ontario, Canada K7L 2V7
    J Crit Care 23:41-9. 2008
    ..In addition, we studied the impact of the clinical and microbiological components of CSVAP on the processes of care and outcomes...
  39. ncbi request reprint Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature
    Leah Gramlich
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Nutrition 20:843-8. 2004
    ..Because EN and PN are associated with risks and benefits, we systematically reviewed and critically appraised the literature to compare EN with PN the critically ill patient...
  40. doi request reprint Knowledge translation interventions for critically ill patients: a systematic review*
    Tasnim Sinuff
    1Department of Critical Care Medicine, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 2Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada 3Department of Medicine, Queen s University, Kingston, ON, Canada 4Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada 5Department of Critical Care Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada 6Department of Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada 7Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada 8Institute of Public Health, University of Calgary, Calgary, AB, Canada 9Center for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada 10Department of Medicine, Providence Health Care and University of British Columbia, Vancouver, BC, Canada 11Department of Medicine, McMaster University, Hamilton, ON, Canada 12Department of Clinical Epidemiology and Biostatistics, Japan
    Crit Care Med 41:2627-40. 2013
    ..We systematically reviewed ICU-based knowledge translation studies to assess the impact of knowledge translation interventions on processes and outcomes of care...
  41. doi request reprint Critical care nutrition support research: lessons learned from recent trials
    Daren K Heyland
    Department of Medicine, Queen s University, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 16:176-81. 2013
    ....
  42. ncbi request reprint Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ont, Canada
    Intensive Care Med 31:327-37. 2005
    ..We investigated whether supplementing critically ill patients with antioxidants, trace elements, and vitamins improves their survival...
  43. ncbi request reprint Nutrition support in the critical care setting: current practice in canadian ICUs--opportunities for improvement?
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 27:74-83. 2003
    ..The purpose of this project was to describe current nutrition support practice in the critical care setting and to identify interventions to target for quality improvement initiatives...
  44. doi request reprint Nutrition therapy in the critical care setting: what is "best achievable" practice? An international multicenter observational study
    Naomi E Cahill
    Department of Community Health and Epidemiology, Queen s University, and Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada
    Crit Care Med 38:395-401. 2010
    ..To describe current nutrition practices in intensive care units and determine "best achievable" practice relative to evidence-based Critical Care Nutrition Clinical Practice Guidelines...
  45. ncbi request reprint Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study
    Daren K Heyland
    Kingston General Hospital Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 31:109-18. 2007
    ..The purpose of this study was to determine the safety of high doses of glutamine combined with antioxidants in critically ill patients...
  46. ncbi request reprint Factors predicting adherence to the Canadian Clinical Practice Guidelines for nutrition support in mechanically ventilated, critically ill adult patients
    Naomi E Jones
    Department of Community Health and Epidemiology, Queen s University, Kingston, ON, Canada
    J Crit Care 23:301-7. 2008
    ..The aim of this study was to determine factors that are associated with adherence to the Canadian nutrition support clinical practice guidelines (CPGs)...
  47. ncbi request reprint Dying in the ICU: perspectives of family members
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, ON, Canada
    Chest 124:392-7. 2003
    ..To describe the perspectives of family members to the care provided to critically ill patients who died in the ICU...
  48. doi request reprint A qualitative study of family involvement in decisions about life support in the intensive care unit
    Jennifer Kryworuchko
    School of Nursing, University of Ottawa, Ontario, Canada
    Am J Hosp Palliat Care 29:36-46. 2012
    ..Family members are unlikely to engage in decision making unless professionals identify the decision and address other barriers to family involvement...
  49. doi request reprint Understanding adherence to guidelines in the intensive care unit: development of a comprehensive framework
    Naomi E Cahill
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:616-24. 2010
    ..The purpose of this study was to develop a comprehensive framework for understanding adherence to nutrition CPGs in the critical care setting...
  50. doi request reprint Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis
    John Muscedere
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 39:1985-91. 2011
    ..New evidence on subglottic secretion drainage as a preventive measure for ventilator-associated pneumonia has been recently published and to consider the evidence in totality, we conducted an updated systematic review and meta-analysis...
  51. pmc Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT)
    Claudio M Martin
    Department of Medicine, Faculty of Medicine, University of Western Ontario, London, Ont
    CMAJ 170:197-204. 2004
    ..We tested the hypothesis that evidence-based algorithms to improve nutritional support in the ICU would improve patient outcomes...
  52. ncbi request reprint The effects of different IV fat emulsions on clinical outcomes in critically ill patients
    Christina E Edmunds
    1Food and Nutrition Services Department, Fraser Health Authority, Burnaby, BC, Canada 2Department of Nutritional Sciences, School of Health Related Professions, Rutgers, The State University of New Jersey, Newark, NJ 3Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada 4Department of Medicine, Queen s University, Kingston, ON, Canada
    Crit Care Med 42:1168-77. 2014
    ..To examine the effects of different IV fat emulsions on clinical outcomes in critically ill patients...
  53. ncbi request reprint Driving perioperative nutrition quality improvement processes forward!
    Daren K Heyland
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 37:83S-98S. 2013
    ....
  54. ncbi request reprint Prevention of ventilator-associated pneumonia: current practice in Canadian intensive care units
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    J Crit Care 17:161-7. 2002
    ..To evaluate the current use of strategies to prevent ventilator-associated pneumonia (VAP) and to identify interventions to target for quality-improvement initiatives...
  55. doi request reprint Barriers to feeding critically ill patients: a multicenter survey of critical care nurses
    Naomi E Cahill
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    J Crit Care 27:727-34. 2012
    ..The aims of this study were to describe the barriers to enterally feeding critically ill patients from a nursing perspective and to examine whether these barriers differ across centers...
  56. doi request reprint Guidelines, guidelines, guidelines: what are we to do with all of these North American guidelines?
    Rupinder Dhaliwal
    Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON, Canada
    JPEN J Parenter Enteral Nutr 34:625-43. 2010
    ..Furthermore, guideline users need to be aware of the dissimilarities in these guidelines before applying the recommendations to their daily practice...
  57. doi request reprint Randomized trials in critical care nutrition: look how far we've come! (and where do we go from here?)
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:697-706. 2010
    ....
  58. doi request reprint The impact of ventilator-associated pneumonia on the Canadian health care system
    John G Muscedere
    Queens University, Kingston, Canada K7L 2V7
    J Crit Care 23:5-10. 2008
    ..Using published data and information from public health care providers, we sought to determine the impact of VAP on the Canadian health care system...
  59. pmc A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care
    Christopher J Longo
    McMaster University, Main Street West, Hamilton, Ontario, Canada, L8S 4M4
    Crit Care 11:R128. 2007
    ..The objective of this study was to evaluate prospectively the effect of APC on long-term HRQoL and resource utilization compared with a nonrandomized control group that received standard care...
  60. pmc Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data
    Donald E G Griesdale
    Department of Medicine, University of British Columbia, Vancouver, Canada
    CMAJ 180:821-7. 2009
    ..We conducted a meta-analysis to update the totality of evidence regarding the influence of intensive insulin therapy compared with conventional insulin therapy on mortality and severe hypoglycemia in the intensive care unit (ICU)...
  61. ncbi request reprint Family satisfaction with care in the intensive care unit: results of a multiple center study
    Daren K Heyland
    Departments of Medicine, Kingston General Hospital, Kingston, Ontario, Canada
    Crit Care Med 30:1413-8. 2002
    ..To determine the level of satisfaction of family members with the care that they and their critically ill relative received...
  62. doi request reprint The adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: an important determinant of outcome
    John G Muscedere
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    J Crit Care 27:322.e7-14. 2012
    ..Accordingly, in patients with CSVAP and timely initiation of empiric antibiotic therapy, we determined the impact of inadequate therapy (IT)...
  63. doi request reprint Pharmaconutrition: a new emerging paradigm
    Naomi E Jones
    Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    Curr Opin Gastroenterol 24:215-22. 2008
    ....
  64. ncbi request reprint Mechanism of injury influences quality of life in survivors of acute respiratory distress syndrome
    Chris M Parker
    Department of Medicine, Queen s University, Kingston, Canada
    Intensive Care Med 32:1895-900. 2006
    ..We examined whether there are differences in quality of life (QOL) in survivors of ARDS attributable to the mechanism of underlying lung injury...
  65. doi request reprint Attitudes and beliefs related to the Canadian critical care nutrition practice guidelines: an international survey of critical care physicians and dietitians
    Naomi E Cahill
    Kingston General Hospital, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:685-96. 2010
    ..The objective of this study was to evaluate the attitudes of critical care practitioners toward the Canadian Critical Care Nutrition Clinical Practice Guidelines (CPGs) and compare them with actual practice...
  66. doi request reprint The relationship between organizational culture and implementation of clinical practice guidelines: a narrative review
    Peter Dodek
    Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    JPEN J Parenter Enteral Nutr 34:669-74. 2010
    ..Further high quality, multimethod studies are required to improve our understanding of how culture influences guideline implementation, and which organizational change strategies might be most effective in optimizing nutrition therapy...
  67. doi request reprint Probiotics in the critically ill: a systematic review of the randomized trial evidence
    Elaine O Petrof
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Crit Care Med 40:3290-302. 2012
    ..The purpose of this systematic review was to evaluate the effect of probiotics in critically ill patients on clinical outcomes...
  68. ncbi request reprint Optimizing the benefits and minimizing the risks of enteral nutrition in the critically ill: role of small bowel feeding
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 26:S51-5; discussion S56-7. 2002
    ..The purpose of this paper is to systematically review those studies that compare gastric with small bowel feeding...
  69. pmc Handover patterns: an observational study of critical care physicians
    Roy Ilan
    Department of Medicine and Critical Care Program, Queen s University, Kingston General Hospital, Etherington Hall, Kingston, ON, Canada, K7L 3N6
    BMC Health Serv Res 12:11. 2012
    ..Thus, our objective is to describe handover communication patterns used by attending critical care physicians in an academic centre and to compare them with currently popular, standardized schemes for handover communication...
  70. ncbi request reprint Optimizing end-of-life care on medical clinical teaching units using the CANHELP questionnaire and a nurse facilitator: a feasibility-study
    Christopher Frank
    Department of Medicine, Kingston General Hospital, Ontario, Canada
    Can J Nurs Res 44:41-58. 2012
    ..Using CANHELP, the nurse facilitator was able to identify opportunities for improving EoL care in patients on medical units and for making small improvements in satisfaction with care...
  71. doi request reprint Mortality, attributable mortality, and clinical events as end points for clinical trials of ventilator-associated pneumonia and hospital-acquired pneumonia
    John G Muscedere
    Queens University and 2Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario, Canada
    Clin Infect Dis 51:S120-5. 2010
    ..Equivalency studies are possible, but there are sample size implications. The use of time to clinical event end points, especially when combined with mortality, may be the best option for trial in the future...
  72. doi request reprint Bridging the guideline-practice gap in critical care nutrition: a review of guideline implementation studies
    Naomi E Cahill
    Kingston General Hospital, Kingston, Ontario, Canada
    JPEN J Parenter Enteral Nutr 34:653-9. 2010
    ..Adopting this tailored approach to guideline implementation in future studies may help bridge the current guideline-practice gap and lead to significant improvements in nutrition practices and patient outcomes...
  73. ncbi request reprint Glutamine supplementation in serious illness: a systematic review of the evidence
    Frantisek Novak
    Department of Medicine, Queens University, Kingston General Hospital, Ontario, Canada
    Crit Care Med 30:2022-9. 2002
    ..To examine the relationship between glutamine supplementation and hospital length of stay, complication rates, and mortality in patients undergoing surgery and experiencing critical illness...
  74. doi request reprint Implementation of clinical practice guidelines for ventilator-associated pneumonia: a multicenter prospective study
    Tasnim Sinuff
    Sunnybrook Research Institute, Sunnybrook Health Sciences Center and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 41:15-23. 2013
    ....
  75. ncbi request reprint Assessment of long-term physical function in acute respiratory distress syndrome (ARDS) patients: comparison of the Charlson Comorbidity Index and the Functional Comorbidity Index
    Dianne L Groll
    Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada
    Am J Phys Med Rehabil 85:574-81. 2006
    ....
  76. ncbi request reprint Combination enteral and parenteral nutrition in critically ill patients: harmful or beneficial? A systematic review of the evidence
    Rupinder Dhaliwal
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    Intensive Care Med 30:1666-71. 2004
    ..This paper systematically reviewed studies that compare EN + PN to enteral nutrition (EN) alone in critically ill patients...
  77. ncbi request reprint Implementation of the Canadian Clinical Practice Guidelines for Nutrition Support: a multiple case study of barriers and enablers
    Naomi E Jones
    Department of Community Health and Epidemiology, Queen s University, 76 Stuart Street, Kingston, ON, Canada, K7L 2V7
    Nutr Clin Pract 22:449-57. 2007
    ..However, their impact to date has been modest. This study aimed to identify important barriers and enablers to implementation of these guidelines...
  78. ncbi request reprint Venous thromboembolism in critical illness in a community intensive care unit
    John G Muscedere
    Department of Medicine, Kingston General Hospital and Queen s University, Kingston, Ontario, Canada K7L 2V7
    J Crit Care 22:285-9. 2007
    ....
  79. ncbi request reprint The seriously ill hospitalized patient: preferred role in end-of-life decision making?
    Daren K Heyland
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    J Crit Care 18:3-10. 2003
    ..Specifically, we ascertained the seriously ill patients' preferred role in the decision-making process, what factors were associated with this role, and how this stated preference related to physicians' perception of preferred role...
  80. ncbi request reprint Fluid restriction for postoperative patients?
    Daren K Heyland
    Division of Gastroenterology, Department of Medicine, Queen s University, Kingston, Ontario K7L 5G2, Canada
    Lancet 359:1792-3. 2002
  81. pmc Determining resuscitation preferences of elderly inpatients: a review of the literature
    Christopher Frank
    Department of Medicine, Queen s University, Kingston, Ont
    CMAJ 169:795-9. 2003
    ..Documentation of discussions and patient preferences may help to minimize misunderstandings and increase the stability of the decision during subsequent admissions to hospital...
  82. ncbi request reprint Gastrointestinal promotility drugs in the critical care setting: a systematic review of the evidence
    Christopher M Booth
    Department of Medicine, Queen s University, Kingston General Hospital, Kingston, Ontario, Canada
    Crit Care Med 30:1429-35. 2002
    ..Gastrointestinal promotility agents may improve tolerance to enteral nutrition, reduce gastroesophageal reflux and pulmonary aspiration, and therefore have the potential to improve outcomes of critically ill patients...
  83. ncbi request reprint Survivors of acute respiratory distress syndrome: relationship between pulmonary dysfunction and long-term health-related quality of life
    Daren K Heyland
    Department of Medicine, Kingston General Hospital, Kingston, Ontario, Canada
    Crit Care Med 33:1549-56. 2005
    ..We describe the pattern of recovery of patients surviving ARDS to illuminate any relationships between lung spirometry values, pulmonary symptoms, and overall HRQOL...