S Davey

Summary

Affiliation: Queen's University
Country: Canada

Publications

  1. pmc Fission yeast rad12+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene
    S Davey
    Department of Oncology, Queen s University, Kingston, Ontario, Canada
    Mol Cell Biol 18:2721-8. 1998
  2. pmc The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1
    R P St Onge
    Cancer Research Laboratories, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Mol Biol Cell 10:1985-95. 1999
  3. ncbi request reprint DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein
    R P St Onge
    Cancer Research Laboratories and the Departments of Pathology, Biochemistry, and Oncology, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Biol Chem 276:41898-905. 2001
  4. pmc HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control gene
    C M Udell
    Cancer Research Laboratories, Department of Oncology and Department of Pathology, Queen s University, Kingston K7L 3N6, Canada
    Nucleic Acids Res 26:3971-6. 1998

Collaborators

  • S K Lee
  • R P St Onge
  • C M Udell
  • R Casselman
  • B D Besley
  • M Park

Detail Information

Publications4

  1. pmc Fission yeast rad12+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene
    S Davey
    Department of Oncology, Queen s University, Kingston, Ontario, Canada
    Mol Cell Biol 18:2721-8. 1998
    ..The physical chromosome segregation defects seen in rad12 null cells combined with the checkpoint regulation defect seen in the rad12+ overproducer implicate rad12+ as a key coupler of chromosomal integrity with cell cycle progression...
  2. pmc The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1
    R P St Onge
    Cancer Research Laboratories, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Mol Biol Cell 10:1985-95. 1999
    ..Finally, we show that hRAD9 is a nuclear protein, indicating that in this signal transduction pathway, hRAD9 is physically proximal to the upstream (DNA damage) signal rather than to the downstream, cytoplasmic, cell cycle machinery...
  3. ncbi request reprint DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein
    R P St Onge
    Cancer Research Laboratories and the Departments of Pathology, Biochemistry, and Oncology, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Biol Chem 276:41898-905. 2001
    ..Unlike the IR-induced phosphorylation at serine 272, this event is dependent on serine 277 and threonine 292, two C-terminal (S/T)P sites in hRad9...
  4. pmc HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control gene
    C M Udell
    Cancer Research Laboratories, Department of Oncology and Department of Pathology, Queen s University, Kingston K7L 3N6, Canada
    Nucleic Acids Res 26:3971-6. 1998
    ..The ability of HRAD1 to partially complement yeast rad1 mutants suggests that this gene is required for G2checkpoint control in human cells...