Shaun Tyler

Summary

Affiliation: Public Health Agency of Canada
Country: Canada

Publications

  1. pmc Distribution and phylogenetic comparisons of a novel mosquito flavivirus sequence present in Culex tarsalis Mosquitoes from western Canada with viruses isolated in California and Colorado
    Shaun Tyler
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    Am J Trop Med Hyg 85:162-8. 2011
  2. doi request reprint Low abundance drug resistance variants in transmitted HIV drug resistance surveillance specimens identified using tagged pooled pyrosequencing
    Hezhao Ji
    National HIV and Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, Canada
    J Virol Methods 187:314-20. 2013
  3. pmc whole-genome sequence of livestock-associated st398 methicillin-resistant staphylococcus aureus Isolated from Humans in Canada
    George R Golding
    National Microbiology Laboratory, Winnipeg, Manitoba, Canada
    J Bacteriol 194:6627-8. 2012
  4. doi request reprint Next-generation sequencing of dried blood spot specimens: a novel approach to HIV drug-resistance surveillance
    Hezhao Ji
    National HIV and Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, ON, Canada
    Antivir Ther 16:871-8. 2011
  5. ncbi request reprint Genetic analysis of Canadian isolates of C:2a:P1.2,5 and B:2a:P1.2,5 Neisseria meningitidis strains belonging to the hypervirulent clone of ET-15
    Shaun Tyler
    Canadian Science Centre for Human and Animal Health, Winnipeg, Canada
    Can J Microbiol 50:433-43. 2004
  6. pmc HIV drug resistance surveillance using pooled pyrosequencing
    Hezhao Ji
    National HIV and Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, Canada
    PLoS ONE 5:e9263. 2010
  7. pmc Nationwide molecular surveillance of pandemic H1N1 influenza A virus genomes: Canada, 2009
    Morag Graham
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    PLoS ONE 6:e16087. 2011
  8. pmc Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada
    David A Boyd
    Nosocomial Infections, National Microbiology Laboratory, 1015 Arlington St, Winnipeg, Manitoba, Canada
    Antimicrob Agents Chemother 48:3758-64. 2004
  9. doi request reprint Immunochemical studies and genetic background of two Neisseria meningitidis isolates expressing unusual capsule polysaccharide antigens with specificities of both serogroup Y and W135
    Raymond S W Tsang
    Laboratory for Vaccine Preventable Bacterial Diseases, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E3R2, Canada
    Can J Microbiol 54:229-34. 2008
  10. pmc Livestock-associated methicillin-resistant Staphylococcus aureus sequence type 398 in humans, Canada
    George R Golding
    National Microbiology Laboratory, Winnipeg, Manitoba, Canada
    Emerg Infect Dis 16:587-94. 2010

Collaborators

Detail Information

Publications15

  1. pmc Distribution and phylogenetic comparisons of a novel mosquito flavivirus sequence present in Culex tarsalis Mosquitoes from western Canada with viruses isolated in California and Colorado
    Shaun Tyler
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    Am J Trop Med Hyg 85:162-8. 2011
    ....
  2. doi request reprint Low abundance drug resistance variants in transmitted HIV drug resistance surveillance specimens identified using tagged pooled pyrosequencing
    Hezhao Ji
    National HIV and Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, Canada
    J Virol Methods 187:314-20. 2013
    ..In conclusion, at considerable savings when compared to commercial assays, TPP produces HIV DR profiles that are concordant with those from SS, furthermore, these same data can be used to identify low abundance drug resistant variants...
  3. pmc whole-genome sequence of livestock-associated st398 methicillin-resistant staphylococcus aureus Isolated from Humans in Canada
    George R Golding
    National Microbiology Laboratory, Winnipeg, Manitoba, Canada
    J Bacteriol 194:6627-8. 2012
    ....
  4. doi request reprint Next-generation sequencing of dried blood spot specimens: a novel approach to HIV drug-resistance surveillance
    Hezhao Ji
    National HIV and Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, ON, Canada
    Antivir Ther 16:871-8. 2011
    ..In this study, we conducted HIV DR surveillance on DBS using NGS and identified minority variants in individual patients...
  5. ncbi request reprint Genetic analysis of Canadian isolates of C:2a:P1.2,5 and B:2a:P1.2,5 Neisseria meningitidis strains belonging to the hypervirulent clone of ET-15
    Shaun Tyler
    Canadian Science Centre for Human and Animal Health, Winnipeg, Canada
    Can J Microbiol 50:433-43. 2004
    ..However, two isolates that appeared identical by all methods employed were temporally and geographically related although no epidemiological evidence is available indicating a link between these strains...
  6. pmc HIV drug resistance surveillance using pooled pyrosequencing
    Hezhao Ji
    National HIV and Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, Canada
    PLoS ONE 5:e9263. 2010
    ....
  7. pmc Nationwide molecular surveillance of pandemic H1N1 influenza A virus genomes: Canada, 2009
    Morag Graham
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    PLoS ONE 6:e16087. 2011
    ..Sequencing has since been conducted at an unprecedented rate globally in order to monitor the diversification of this emergent virus and to track mutations that may affect virus behavior...
  8. pmc Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada
    David A Boyd
    Nosocomial Infections, National Microbiology Laboratory, 1015 Arlington St, Winnipeg, Manitoba, Canada
    Antimicrob Agents Chemother 48:3758-64. 2004
    ..coli strain isolated in India in 1999, revealed that the plasmids had several features in common, including an R100 backbone and several of the resistance genes, including bla(CTX-M-15), bla(TEM-1), bla(OXA-1), tetA, and aac(6')-Ib...
  9. doi request reprint Immunochemical studies and genetic background of two Neisseria meningitidis isolates expressing unusual capsule polysaccharide antigens with specificities of both serogroup Y and W135
    Raymond S W Tsang
    Laboratory for Vaccine Preventable Bacterial Diseases, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E3R2, Canada
    Can J Microbiol 54:229-34. 2008
    ..How these strains may affect results of routine surveillance, PCR diagnosis, and immuno-protection by vaccination are discussed...
  10. pmc Livestock-associated methicillin-resistant Staphylococcus aureus sequence type 398 in humans, Canada
    George R Golding
    National Microbiology Laboratory, Winnipeg, Manitoba, Canada
    Emerg Infect Dis 16:587-94. 2010
    ..Although prevalence of livestock-associated MRSA seems to be low for the general population in Canada, recent emergence of infections resulting from this strain is of public health concern...
  11. pmc High-throughput genome sequencing of two Listeria monocytogenes clinical isolates during a large foodborne outbreak
    Matthew W Gilmour
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada
    BMC Genomics 11:120. 2010
    ..monocytogenes isolates was used to rapidly provide the genome sequence of the primary outbreak strain and to investigate the extent of genetic diversity associated with a change of a single restriction enzyme fragment during PFGE...
  12. pmc Molecular definition of vaginal microbiota in East African commercial sex workers
    John J Schellenberg
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada
    Appl Environ Microbiol 77:4066-74. 2011
    ..We conclude that cpn60 UT is ideally suited to next-generation sequencing technologies for further investigation of microbial community dynamics and mucosal immunity underlying HIV resistance in this cohort...
  13. doi request reprint Human infection with a triple-reassortant swine influenza A(H1N1) virus containing the hemagglutinin and neuraminidase genes of seasonal influenza virus
    Nathalie Bastien
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    J Infect Dis 201:1178-82. 2010
    ..The neuraminidase and hemagglutinin genes of A/Saskatchewan/5350/2009, A/Saskatchewan/5351/2009, and A/Saskatchewan/5131/2009 were derived from human H1N1 virus and were closely related to those of A/Brisbane/59/2007...
  14. pmc VanG-type vancomycin-resistant Enterococcus faecalis strains isolated in Canada
    David A Boyd
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba
    Antimicrob Agents Chemother 50:2217-21. 2006
    ..faecalis BM4518. E. faecalis N03-0233 (vancomycin MIC, 16 microg/ml) was found to harbor a novel vanG operon, vanG2, on an element in a different chromosomal location than the vanG-harboring elements in G1-0247 and BM4518...
  15. pmc Pyrosequencing of the chaperonin-60 universal target as a tool for determining microbial community composition
    John Schellenberg
    Department of Medical Microbiology, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba R3E 0W3, Canada
    Appl Environ Microbiol 75:2889-98. 2009
    ..These observations demonstrate that pyrosequencing of cpn60 UT amplicons provides a robust, reliable method for deep sequencing of microbial communities...