Marc Pouliot

Summary

Country: Canada

Publications

  1. pmc Nucleobindin co-localizes and associates with cyclooxygenase (COX)-2 in human neutrophils
    Patrick Leclerc
    Centre de Recherche en Rhumatologie et Immunologie and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada
    PLoS ONE 3:e2229. 2008
  2. pmc Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways
    Mireille St-Onge
    Department of Anatomy Physiology, Faculty of Medicine, Centre de Recherche en Rhumatologie et Immunologie du CHUQ, Laval University, Quebec City, Quebec, Canada
    PLoS ONE 4:e4902. 2009
  3. ncbi request reprint Adenosine up-regulates cyclooxygenase-2 in human granulocytes: impact on the balance of eicosanoid generation
    Marc Pouliot
    Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du Centre Hospitalier Universitaire de Québec, and Faculté de Médecine, Universite Laval, Canada
    J Immunol 169:5279-86. 2002
  4. pmc Potentiation of neutrophil cyclooxygenase-2 by adenosine: an early anti-inflammatory signal
    Jean Sébastien Cadieux
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ CHUL, and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec, Canada, G1V 4G2
    J Cell Sci 118:1437-47. 2005
  5. pmc Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils
    Mireille St-Onge
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ CHUL, Sainte Foy, and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec, Canada, and Rheumatology Unit, Royal Adelaide Hospital, SA, Australia
    Biochim Biophys Acta 1771:1235-45. 2007
  6. pmc Immunomodulatory impact of the A2A adenosine receptor on the profile of chemokines produced by neutrophils
    Shaun R McColl
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ CHUL, and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec, Canada
    FASEB J 20:187-9. 2006
  7. ncbi request reprint Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals
    Caroline Gilbert
    Laval University, Ste Foy, Quebec, Canada
    Arthritis Rheum 48:1137-48. 2003
  8. doi request reprint Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo
    Aline Dumas
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ, and Department of Microbiology Infectiology and Immunology, Faculty of Medicine, Laval University, Quebec City, QC, Canada
    J Cell Mol Med 16:1274-85. 2012
  9. ncbi request reprint The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis
    Kim Hattermann
    Centre de Recherche en Rhumatologie et Immunologie, Centre Hospitalier Universitaire de Quebec Research Center and Faculty of Medicine, Laval University, Quebec, Canada
    FASEB J 21:1575-85. 2007
  10. pmc Proteinase-activated receptor-2 up-regulation by Fcgamma-receptor activation in human neutrophils
    Mireille St-Onge
    Centre de Recherche en Rhumatologie et Immunologie du Centre Hospitalier Universitaire de Québec, Department of Microbiology Infectiology and Immunology, Faculty of Medicine, Laval University, Quebec, Canada
    FASEB J 24:2116-25. 2010

Collaborators

Detail Information

Publications16

  1. pmc Nucleobindin co-localizes and associates with cyclooxygenase (COX)-2 in human neutrophils
    Patrick Leclerc
    Centre de Recherche en Rhumatologie et Immunologie and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada
    PLoS ONE 3:e2229. 2008
    ..Moreover, neutrophil transfection with hrNuc specifically enhanced PGE(2) biosynthesis. Together, these results identify a COX-2-associated protein which may have an impact in prostanoid biosynthesis...
  2. pmc Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways
    Mireille St-Onge
    Department of Anatomy Physiology, Faculty of Medicine, Centre de Recherche en Rhumatologie et Immunologie du CHUQ, Laval University, Quebec City, Quebec, Canada
    PLoS ONE 4:e4902. 2009
    ..Identification of these pathways will improve understanding of the capacity of tissues to terminate inflammatory responses and contribute to the development of therapeutic strategies based on endogenous resolution...
  3. ncbi request reprint Adenosine up-regulates cyclooxygenase-2 in human granulocytes: impact on the balance of eicosanoid generation
    Marc Pouliot
    Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du Centre Hospitalier Universitaire de Québec, and Faculté de Médecine, Universite Laval, Canada
    J Immunol 169:5279-86. 2002
    ....
  4. pmc Potentiation of neutrophil cyclooxygenase-2 by adenosine: an early anti-inflammatory signal
    Jean Sébastien Cadieux
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ CHUL, and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec, Canada, G1V 4G2
    J Cell Sci 118:1437-47. 2005
    ....
  5. pmc Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils
    Mireille St-Onge
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ CHUL, Sainte Foy, and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec, Canada, and Rheumatology Unit, Royal Adelaide Hospital, SA, Australia
    Biochim Biophys Acta 1771:1235-45. 2007
    ..These results highlight key differences in regulatory processes of the 5-LO and COX pathways, and enhance our knowledge at several levels in the PGE2 biosynthesis in neutrophils...
  6. pmc Immunomodulatory impact of the A2A adenosine receptor on the profile of chemokines produced by neutrophils
    Shaun R McColl
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ CHUL, and Department of Anatomy Physiology, Faculty of Medicine, Laval University, Quebec, Canada
    FASEB J 20:187-9. 2006
    ..Modulation by A2AR in the production of inflammatory signals by PMNs may thus influence the evolution of an inflammatory response by reducing the activation status of inflammatory cells...
  7. ncbi request reprint Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals
    Caroline Gilbert
    Laval University, Ste Foy, Quebec, Canada
    Arthritis Rheum 48:1137-48. 2003
    ..To evaluate the impact of monosodium urate monohydrate (MSUM) crystals on the synthesis of prostaglandin E(2) (PGE(2)) by human neutrophils, and to examine some of the mechanisms underlying these responses...
  8. doi request reprint Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo
    Aline Dumas
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ, and Department of Microbiology Infectiology and Immunology, Faculty of Medicine, Laval University, Quebec City, QC, Canada
    J Cell Mol Med 16:1274-85. 2012
    ..These results as a whole suggest an anti-inflammatory role for OSM, guiding inflammatory processes towards resolution...
  9. ncbi request reprint The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis
    Kim Hattermann
    Centre de Recherche en Rhumatologie et Immunologie, Centre Hospitalier Universitaire de Quebec Research Center and Faculty of Medicine, Laval University, Quebec, Canada
    FASEB J 21:1575-85. 2007
    ..These studies demonstrate that TLR8 signaling strongly promotes inflammatory lipid mediator biosynthesis and provide novel insights on innate immune response to viral infections...
  10. pmc Proteinase-activated receptor-2 up-regulation by Fcgamma-receptor activation in human neutrophils
    Mireille St-Onge
    Centre de Recherche en Rhumatologie et Immunologie du Centre Hospitalier Universitaire de Québec, Department of Microbiology Infectiology and Immunology, Faculty of Medicine, Laval University, Quebec, Canada
    FASEB J 24:2116-25. 2010
    ..This enhanced response to PAR-2 activation indicates that molecular communication between pain and inflammation may be more important than previously believed...
  11. doi request reprint [Neutrophil: foe or friend?]
    Aline Dumas
    Centre de Recherche en Rhumatologie et Immunologie du CHUQ, et département d anatomie physiologie, CHUL, Faculte de Medecine, Universite Laval, 2705, boulevard Laurier, Bureau T1 49, Québec Québec, G1V 4G2 Canada
    Med Sci (Paris) 25:699-704. 2009
    ..These endogenous resolution pathways may represent a key target for better treatments of inflammatory diseases...
  12. pmc Human neutrophils as a source of nociceptin: a novel link between pain and inflammation
    Marie Elaine Fiset
    Centre de Recherche en Rhumatologie et Immunologie, Faculte de Medecine, Universite Laval, 2705 Laurier Boulevard, Office T1 49, Quebec, Canada G1V 4G2
    Biochemistry 42:10498-505. 2003
    ..Taken together, these results show that nociceptin/NociR is present and functional in human neutrophils, and the results identify a novel dialogue pathway between neural and immune tissues...
  13. doi request reprint Osteoblast retraction induced by adherent neutrophils promotes osteoclast bone resorption: implication for altered bone remodeling in chronic gout
    Isabelle Allaeys
    Department of Medicine, Faculty of Medicine, Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du CHUL, Universite Laval, Quebec, Canada
    Lab Invest 91:905-20. 2011
    ..These interactions could be involved in the local bone remodeling process of gout...
  14. ncbi request reprint TNF-α expression in neutrophils and its regulation by glycogen synthase kinase-3: A potentiating role for lithium
    Miriam S Giambelluca
    Centre de Recherche du Centre Hospitalier Universitaire de Québec and Faculty of Medicine, Universite Laval, Quebec City, Quebec, Canada and
    FASEB J 28:3679-90. 2014
    ..Giambelluca, M. S., Bertheau-Mailhot, G., Laflamme, C., Rollet-Labelle, E., Servant, M. J., Pouliot, M. TNF-α expression in neutrophils and its regulation by glycogen synthase kinase-3: a potentiating role for lithium. ..
  15. doi request reprint Expression and regulation of glycogen synthase kinase 3 in human neutrophils
    Miriam S Giambelluca
    Centre de Recherche du CHU de Québec and Faculty of Medicine, Universite Laval, Quebec City, Canada
    Int J Biochem Cell Biol 45:2660-5. 2013
    ..We conclude that GSK-3α is the main isoform expressed in neutrophils and that many different pathways can converge to inhibit GSK-3α activity via Ser21-phosphorylation. GSK-3α thus might be a hub of cellular regulation. ..