Paul Poirier

Summary

Country: Canada

Publications

  1. pmc Impact of orlistat-induced weight loss on diastolic function and heart rate variability in severely obese subjects with diabetes
    Julie Martin
    Institut Universitaire de Cardiologie et de Pneumologie de Québec IUCPQ, 2725 Chemin Ste Foy, QC, Canada G1V 4G5
    J Obes 2011:394658. 2011
  2. ncbi request reprint Role of bariatric surgery in diabetes
    Paul Poirier
    Laval University, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec, Quebec, G1V 4G5, Canada
    Curr Cardiol Rep 16:444. 2014
  3. pmc Development and validation of a predictive model of acute glucose response to exercise in individuals with type 2 diabetes
    Bryan S Gibson
    Veterans Affairs Medical Center, Salt Lake City, UT, USA
    Diabetol Metab Syndr 5:33. 2013
  4. doi request reprint Long term efficacy of abciximab bolus-only compared to abciximab bolus and infusion after transradial coronary stenting
    Rodrigo Bagur
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Catheter Cardiovasc Interv 74:1010-6. 2009
  5. doi request reprint Changes in predicted cardiovascular disease risk after biliopancreatic diversion surgery in severely obese patients
    Marie Eve Piché
    Quebec Heart and Lung Institute Laval University, Quebec, Canada
    Metabolism 63:79-86. 2014
  6. ncbi request reprint Early and late outcomes in patients excluded from same-day home discharge after transradial stenting and maximal antiplatelet therapy
    Olivier F Bertrand
    Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Quebec, Canada
    Catheter Cardiovasc Interv 72:619-25. 2008
  7. doi request reprint Exercise capacity in patients with severe symptomatic aortic stenosis before and six months after transcatheter aortic valve implantation
    Rodrigo Bagur
    Quebec Heart and Lung Institute, Laval University, Quebec City, Canada
    Am J Cardiol 108:258-64. 2011
  8. ncbi request reprint Influence of obesity indices, metabolic parameters and age on cardiac autonomic function in abdominally obese men
    Natalia Poliakova
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Metabolism 61:1270-9. 2012
  9. doi request reprint Cardiometabolic effects of rosiglitazone in patients with type 2 diabetes and coronary artery bypass grafts: A randomized placebo-controlled clinical trial
    Olivier F Bertrand
    Quebec Heart Lung Institute, Quebec, Canada
    Atherosclerosis 211:565-73. 2010
  10. doi request reprint Insulin resistance, low cardiorespiratory fitness, and increased exercise blood pressure: contribution of abdominal obesity
    Maxime Huot
    Division of Kinesiology, Department of Social and Preventive Medicine, Universite Laval, Quebec, Quebec, Canada
    Hypertension 58:1036-42. 2011

Detail Information

Publications92

  1. pmc Impact of orlistat-induced weight loss on diastolic function and heart rate variability in severely obese subjects with diabetes
    Julie Martin
    Institut Universitaire de Cardiologie et de Pneumologie de Québec IUCPQ, 2725 Chemin Ste Foy, QC, Canada G1V 4G5
    J Obes 2011:394658. 2011
    ..04) in the Orlistat group. Conclusion. These results suggest that a modest weight loss improves fasting glycemia, left ventricular diastolic function, and sympathovagal balance in severely obese patients with type 2 diabetes...
  2. ncbi request reprint Role of bariatric surgery in diabetes
    Paul Poirier
    Laval University, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec, Quebec, G1V 4G5, Canada
    Curr Cardiol Rep 16:444. 2014
    ..As diabetes is a lifelong disease, it is important to emphasize that a certain percentage of patients will suffer from relapse of their diabetes...
  3. pmc Development and validation of a predictive model of acute glucose response to exercise in individuals with type 2 diabetes
    Bryan S Gibson
    Veterans Affairs Medical Center, Salt Lake City, UT, USA
    Diabetol Metab Syndr 5:33. 2013
    ..Our purpose was to develop and test a predictive model of the acute glucose response to exercise in individuals with type 2 diabetes...
  4. doi request reprint Long term efficacy of abciximab bolus-only compared to abciximab bolus and infusion after transradial coronary stenting
    Rodrigo Bagur
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Catheter Cardiovasc Interv 74:1010-6. 2009
    ..No data are available on the long term efficacy of abciximab bolus-only with aspirin and clopidogrel pretreatment and systematic coronary stenting. Our objective was to evaluate the 3-year clinical outcomes in the EASY trial...
  5. doi request reprint Changes in predicted cardiovascular disease risk after biliopancreatic diversion surgery in severely obese patients
    Marie Eve Piché
    Quebec Heart and Lung Institute Laval University, Quebec, Canada
    Metabolism 63:79-86. 2014
    ..To determine the impact of biliopancreatic diversion with duodenal switch (BPD-DS) surgery on cardiovascular risk profile and predicted cardiovascular risk in severely obese patients...
  6. ncbi request reprint Early and late outcomes in patients excluded from same-day home discharge after transradial stenting and maximal antiplatelet therapy
    Olivier F Bertrand
    Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Quebec, Canada
    Catheter Cardiovasc Interv 72:619-25. 2008
    ..Based on a few angiographic criteria, suboptimal results, or clinical complications, some patients were excluded from randomization after PCI...
  7. doi request reprint Exercise capacity in patients with severe symptomatic aortic stenosis before and six months after transcatheter aortic valve implantation
    Rodrigo Bagur
    Quebec Heart and Lung Institute, Laval University, Quebec City, Canada
    Am J Cardiol 108:258-64. 2011
    ..These results suggest that the 6MWT might become an important tool as a part of the evaluation process for TAVI candidates...
  8. ncbi request reprint Influence of obesity indices, metabolic parameters and age on cardiac autonomic function in abdominally obese men
    Natalia Poliakova
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Metabolism 61:1270-9. 2012
    ..An approach considering the combination of age, obesity and glucose metabolism factors could be helpful in the global cardiovascular risk management in abdominally obese men...
  9. doi request reprint Cardiometabolic effects of rosiglitazone in patients with type 2 diabetes and coronary artery bypass grafts: A randomized placebo-controlled clinical trial
    Olivier F Bertrand
    Quebec Heart Lung Institute, Quebec, Canada
    Atherosclerosis 211:565-73. 2010
    ..To assess the efficacy and safety of rosiglitazone on saphenous vein graft (SVG) atherosclerosis prevention and on modification of the global cardiometabolic risk profile...
  10. doi request reprint Insulin resistance, low cardiorespiratory fitness, and increased exercise blood pressure: contribution of abdominal obesity
    Maxime Huot
    Division of Kinesiology, Department of Social and Preventive Medicine, Universite Laval, Quebec, Quebec, Canada
    Hypertension 58:1036-42. 2011
    ..05). Individuals with a higher waist circumference have elevated exercise systolic blood pressure, regardless of their insulin sensitivity or level of cardiorespiratory fitness...
  11. doi request reprint Visceral and not subcutaneous abdominal adiposity reduction drives the benefits of a 1-year lifestyle modification program
    Anne Laure Borel
    Department of Cardiology, Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Quebec, Canada
    Obesity (Silver Spring) 20:1223-33. 2012
    ..Furthermore, the reduction in VAT was independently related to the reduction in global adiposity and to the improvement in cardiorespiratory fitness...
  12. ncbi request reprint Changes in both global diet quality and physical activity level synergistically reduce visceral adiposity in men with features of metabolic syndrome
    Julie Anne Nazare
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    J Nutr 143:1074-83. 2013
    ....
  13. doi request reprint The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis
    Salvatore Mottillo
    Jewish General Hospital McGill University, Montreal, Quebec, Canada
    J Am Coll Cardiol 56:1113-32. 2010
    ....
  14. doi request reprint Transient myocardial tissue and function changes during a marathon in less fit marathon runners
    Valérie Gaudreault
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec City, Quebec, Canada Faculty of Medicine, Universite Laval, Quebec City, Quebec, Canada
    Can J Cardiol 29:1269-76. 2013
    ..Although regular physical activity improves health, strenuous exercise might transiently increase cardiac risk. Training and fitness might provide protection...
  15. doi request reprint Incidence, range, and clinical effect of hemoglobin changes within 24 hours after transradial coronary stenting
    Olivier F Bertrand
    Quebec Heart Lung Institute, Quebec, Quebec, Canada
    Am J Cardiol 106:155-61. 2010
    ..Measures to prevent anemia and blood loss during PCI remain to be further studied...
  16. ncbi request reprint Acute and chronic effects of biliopancreatic diversion with duodenal switch surgery on plasma visfatin and apelin levels in patients with severe obesity
    Sarah Maude Caron-Cantin
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec City, QC, Canada, G1V 4G5
    Obes Surg 23:1806-14. 2013
    ..Apelin is an adipokine with positive cardiac inotropic effects, and it may be related to inflammatory molecules. Variations in plasma visfatin and apelin levels following bariatric surgery remain controversial...
  17. ncbi request reprint Blood pressure assessment in severe obesity: validation of a forearm approach
    Marie Eve Leblanc
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada Faculté de pharmacie de l Université Laval, Quebec, Canada
    Obesity (Silver Spring) 21:E533-41. 2013
    ..The aim of the study is to assess the degree of agreement between the intra-arterial method as the gold standard vs. noninvasive methods, i.e., forearm blood pressure and upper-arm blood pressure measures...
  18. doi request reprint Sleep apnoea attenuates the effects of a lifestyle intervention programme in men with visceral obesity
    Anne Laure Borel
    Department of Pneumology, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec, Canada
    Thorax 67:735-41. 2012
    ..Excess visceral adiposity and sleep apnoea are two conditions independently associated with cardiovascular diseases. The two conditions are often combined and are believed to interact in a vicious circle...
  19. ncbi request reprint Overview of epidemiology and contribution of obesity to cardiovascular disease
    Marjorie Bastien
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, QC, Canada Faculté de Pharmacie, Universite Laval, Quebec, QC, Canada
    Prog Cardiovasc Dis 56:369-81. 2014
    ..Thus, the evidence reviewed in this paper suggests that adipose tissue quality/function is as important, if not more so, than its amount in determining the overall health and CV risks of overweight/obesity. ..
  20. doi request reprint Impact of visceral obesity on cardiac parasympathetic activity in type 2 diabetics after coronary artery bypass graft surgery
    Guillaume Salamin
    Département de Kinésiologie, Faculte de Medecine, Universite Laval, Quebec, Canada
    Obesity (Silver Spring) 21:1578-85. 2013
    ..We evaluated the associations between indices of adiposity and HRV in patients with T2D with CABG and quantified the relationships of the volume of visceral (VVAT) and subcutaneous adipose tissue (VSAT) to HRV...
  21. doi request reprint One-year clinical outcome after abciximab bolus-only compared with abciximab bolus and 12-hour infusion in the Randomized EArly Discharge after Transradial Stenting of CoronarY Arteries (EASY) Study
    Olivier F Bertrand
    Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Quebec, Canada
    Am Heart J 156:135-40. 2008
    ..The purpose of this study is to compare 6- and 12-month clinical outcomes in patients treated after PCI with abciximab bolus-only and abciximab bolus followed by 12-hour infusion...
  22. doi request reprint Normalization of visceral adiposity is required to normalize plasma apolipoprotein B levels in response to a healthy eating/physical activity lifestyle modification program in viscerally obese men
    Emilie Pelletier-Beaumont
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Atherosclerosis 221:577-82. 2012
    ..We have examined the effects of a 1-year lifestyle modification program on plasma apoB levels in viscerally obese men and compared post-intervention levels to those of a reference group of lean healthy men...
  23. doi request reprint Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk
    Jean Pierre Despres
    Hôpital Laval Research Centre, 2725 Chemin Ste Foy, Pavilion Marguerite D Youville, 4th Floor, Quebec City, QC G1V4G5, Canada
    Arterioscler Thromb Vasc Biol 28:1039-49. 2008
    ....
  24. ncbi request reprint Normalization of diastolic dysfunction in type 2 diabetics after exercise training
    Patrice Brassard
    Laval Hospital Research Center, Quebec Heart and Lung Institute, Quebec, Canada
    Med Sci Sports Exerc 39:1896-901. 2007
    ..The purpose of this study was to evaluate the impact of aerobic exercise training on left ventricular diastolic dysfunction (LVDD) and exercise capacity in subjects with type 2 diabetes...
  25. doi request reprint Comparison of myocardial ischemia on the ergocycle versus the treadmill in patients with coronary heart disease
    Martin Noel
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Am J Cardiol 105:633-9. 2010
    ....
  26. doi request reprint Isolated aerobic exercise and weight loss: a systematic review and meta-analysis of randomized controlled trials
    Adrian Thorogood
    Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital McGill University, Montreal, Quebec, Canada
    Am J Med 124:747-55. 2011
    ..We conducted a systematic review and meta-analysis to evaluate the efficacy of isolated aerobic exercise programs in overweight and obese populations...
  27. doi request reprint Impact of bariatric surgery on N-terminal fragment of the prohormone brain natriuretic peptide and left ventricular diastolic function
    Julie Martin
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Quebec, Canada
    Can J Cardiol 29:969-75. 2013
    ..Our objective was to determine the impact of bariatric surgery-induced weight loss on NT-proBNP levels and LV DD...
  28. doi request reprint Exercise-induced hypertension in men with metabolic syndrome: anthropometric, metabolic, and hemodynamic features
    Valérie Gaudreault
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval, Quebec, Canada
    Metab Syndr Relat Disord 11:7-14. 2013
    ..The aim of this study was to evaluate exercise-induced hypertension (EIH) in men with metabolic syndrome and to explore potential associations with anthropometric and metabolic variables...
  29. ncbi request reprint The ACE-DD genotype is associated with endothelial dysfunction in postmenopausal women
    Julie Méthot
    Quebec Heart Institute Laval Hospital, Laval University, Ste Foy, Quebec, Canada
    Menopause 13:959-66. 2006
    ....
  30. ncbi request reprint Influence of glycemic control on pulmonary function and heart rate in response to exercise in subjects with type 2 diabetes mellitus
    Patrice Brassard
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Universite Laval, Ste Foy, Quebec, Canada G1V 4G5
    Metabolism 55:1532-7. 2006
    ....
  31. doi request reprint Upregulation of plasma insulin-like growth factor binding protein 2 levels after biliopancreatic diversion in humans
    Zhuo Li
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Laval University, Quebec, Quebec, Canada
    Obesity (Silver Spring) 20:1469-73. 2012
    ..The mechanisms for the augmentation in IGFBP-2 after BPD-DS and its contribution to insulin sensitization remain to be elucidated...
  32. ncbi request reprint Can prolonged exercise-induced myocardial ischaemia be innocuous?
    Martin Noel
    Quebec Heart Institute, Laval Hospital, Laval University, 2725 Chemin Ste Foy, Ste Foy, Quebec, Canada G1V 4G5
    Eur Heart J 28:1559-65. 2007
    ..To evaluate the innocuousness of intense and prolonged exercise training above the threshold for myocardial ischaemia (1 mm ST-segment depression)...
  33. ncbi request reprint Effects of exogenous metabolic substrate modulation on exercise-induced myocardial ischemia
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, Laval University, Quebec City, Quebec, Canada
    Am Heart J 156:790-6. 2008
    ..The aim of the study is to compare the impact of intravenous glucose versus lipid versus saline on exercise-induced myocardial ischemia in patients with stable angina...
  34. ncbi request reprint Daily steps threshold to improve cardiovascular disease risk factors during the year after an acute coronary syndrome
    Julie Houle
    Nursing Department, Universite du Quebec a Trois Rivieres, Dr Houle, Axe Santé Publique et Pratiques Optimales en Santé, Centre de recherche du CHUQ, Dr Valera, Institut universitaire de cardiologie et pneumologie de Québec Ms Gaudet Savard and Dr Poirier, and Faculty of Pharmacy, Laval University, Quebec City Ms Auclair and Dr Poirier, Quebec, Canada
    J Cardiopulm Rehabil Prev 33:406-10. 2013
    ..To evaluate the daily steps threshold associated with improved cardiovascular disease risk factors during the first year following an acute coronary syndrome...
  35. ncbi request reprint Impact of bariatric surgery--induced weight loss on heart rate variability
    Isabelle Nault
    Department of Cardiology, Institut Universitaire de Cardiologie et de Pneumologie, Hopital Laval, Quebec, Canada G1V 4G5
    Metabolism 56:1425-30. 2007
    ..Weight loss after bariatric surgery enhances HRV and decreases mean and minimal heart rate during Holter monitoring through a better cardiac parasympathetic modulation...
  36. ncbi request reprint Impact of beta-blocker treatment and nutritional status on glycemic response during exercise in patients with type 2 diabetes
    Annie Ferland
    Centre de Recherche de l Hopital Laval, Institut universitaire de cardiologie et de pneumologie del Université Laval, Quebec, Canada
    Clin Invest Med 30:E257-61. 2007
    ..The objective of the study was to assess the impact of beta-blocker treatment on glucose response during exercise in patients with type 2 diabetes, free of cardiovascular complications...
  37. pmc Effects of aerobic exercise training and irbesartan on blood pressure and heart rate variability in patients with chronic obstructive pulmonary disease
    Karine Marquis
    Centre de Recherche de l Hopital Laval, Institut universitaire de cardiologie et de pneumoloigie de L Université Laval, Quebec, Canada
    Can Respir J 15:355-60. 2008
    ....
  38. doi request reprint Effect of bisoprolol on respiratory function and exercise capacity in chronic obstructive pulmonary disease
    Vincent Mainguy
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Faculte de Medecine, Universite Laval, Quebec, Canada
    Am J Cardiol 110:258-63. 2012
    ..The magnitude of these effects was small and should not contraindicate the use of bisoprolol in patients with COPD...
  39. doi request reprint Plasma adipokine and hormone changes in mountaineers on ascent to 5300 meters
    Jessica D Smith
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Laval University, Quebec, QC, Canada
    Wilderness Environ Med 22:107-14. 2011
    ..In particular, acylation-stimulating protein (ASP), which influences fat storage in adipose tissue, has not been measured at high altitude...
  40. ncbi request reprint Different thresholds of myocardial ischemia in ramp and standard bruce protocol exercise tests in patients with positive exercise stress tests and angiographically demonstrated coronary arterial narrowing
    Martin Noel
    Quebec Heart Institute Laval Hospital, Laval Sainte University Foy, Quebec, Canada
    Am J Cardiol 99:921-4. 2007
    ..This effect is unexplained by energy expenditure (VO2) or myocardial work (RPP) and is consistent with a "warm-up" ischemic mechanism...
  41. doi request reprint Incidence, predictors, and clinical impact of bleeding after transradial coronary stenting and maximal antiplatelet therapy
    Olivier F Bertrand
    Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Quebec City, Quebec, Canada
    Am Heart J 157:164-9. 2009
    ..We evaluated the predictors of bleeding and the impact of major bleeding on death and major adverse cardiac events (MACE) after transradial PCI and maximal antiplatelet therapy...
  42. ncbi request reprint The cardiovascular effects of peroxisome proliferator-activated receptor agonists
    Sayuri N Friedland
    Division of Cardiology, Jewish General Hospital McGill University, Montreal, Quebec, Canada
    Am J Med 125:126-33. 2012
    ..The critical question of why peroxisome proliferator-activated receptor agonists seem to improve cardiovascular risk factors without significantly improving cardiovascular outcomes requires further investigation...
  43. ncbi request reprint Effectiveness of a pedometer-based program using a socio-cognitive intervention on physical activity and quality of life in a setting of cardiac rehabilitation
    Julie Houle
    Faculty of Pharmacy, Laval University, Quebec City, Quebec, Canada
    Can J Cardiol 28:27-32. 2012
    ..Physical activity contributes to improve health and quality of life. However, the prevalence of sedentary lifestyle is elevated after an acute coronary syndrome...
  44. pmc A multicentre, randomized, double-blind placebo-controlled trial evaluating rosiglitazone for the prevention of atherosclerosis progression after coronary artery bypass graft surgery in patients with type 2 diabetes. Design and rationale of the VeIn-Coron
    Olivier F Bertrand
    Hopital Laval, Quebec Heart Lung Institute, Quebec, Quebec, Canada
    Can J Cardiol 25:509-15. 2009
    ..However, its role in the prevention of atherosclerosis progression is uncertain...
  45. doi request reprint Oxidized low-density lipoprotein, angiotensin II and increased waist cirumference are associated with valve inflammation in prehypertensive patients with aortic stenosis
    Nancy Côté
    Laboratoire d Études Moléculaires des Valvulopathies LEMV, Laval Hospital Research Center Quebec Heart Institute, Department of Surgery, Laval University, Quebec, Canada
    Int J Cardiol 145:444-9. 2010
    ..We sought to determine the relationships between blood pressure, inflammation, oxidative stress and valvular inflammation in a population of normotensive and prehypertensive patients with AS...
  46. doi request reprint Assessment of management of cardiovascular risk factors in patients with thoracic aortic disease
    Marjorie Bastien
    Quebec Heart and Lung Institute, Quebec, Canada
    Blood Press Monit 17:235-42. 2012
    ..Cardiovascular risk profiles and adiposity assessment data in patients with thoracic aortic disease (TAD) are sparse...
  47. ncbi request reprint Is severe obesity a cardiovascular health concern in the Inuit population?
    Samantha Kellett
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Quebec, Canada
    Am J Hum Biol 24:441-5. 2012
    ..Amongst the Inuit, evolution of SO remains unknown. We investigated whether the level of SO changed and whether the cardio-metabolic profile improved or deteriorated in Nunavik Inuit between 1992 and 2004...
  48. pmc Usefulness of an accelerated transoesophageal stress echocardiography in the preoperative evaluation of high risk severely obese subjects awaiting bariatric surgery
    Sylvie Legault
    Department of Cardiology, Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Cardiovasc Ultrasound 8:30. 2010
    ....
  49. ncbi request reprint Environmental mercury exposure and blood pressure among Nunavik Inuit adults
    Beatriz Valera
    Axe Santé des Populations et Environnement, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Quebec, Canada
    Hypertension 54:981-6. 2009
    ..96; P=0.069). In conclusion, mercury is associated with increasing BP and pulse pressure among Nunavik Inuit adults after considering the effect of fish nutrients (n-3 fatty acids and selenium) and other confounders...
  50. ncbi request reprint Safety and magnitude of changes in blood glucose levels following exercise performed in the fasted and the postprandial state in men with type 2 diabetes
    Thierry Gaudet-Savard
    Quebec Heart and Lungs Institute, Laval Hospital, Sainte Foy, Quebec, Canada
    Eur J Cardiovasc Prev Rehabil 14:831-6. 2007
    ..For this reason, the effects of exercise initiated at different preexercise BGL were assessed in men with type 2 diabetes both in the fasted (FS) and the postprandial states (PS)...
  51. doi request reprint Visceral obesity and the heart
    Patrick Mathieu
    Laval Hospital Research Center Quebec Heart Institute, Department of Surgery, Laval University, 2725 Chemin Ste Foy, Quebec, Canada, G1V 4G5
    Int J Biochem Cell Biol 40:821-36. 2008
    ..Implications and failure of lipid partitioning and some of the potential pathways mediating development of heart diseases are also covered in view of recent development of therapeutic options...
  52. ncbi request reprint Cardiorespiratory screening in elite endurance sports athletes: the Quebec study
    Julie Turmel
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec City, Quebec, Canada
    Phys Sportsmed 40:55-65. 2012
    ..The aim of this study was to evaluate, in a research setting, the prevalence of cardiorespiratory disorders in athletes in order to determine the potential value of a screening program...
  53. doi request reprint Exaggerated blood pressure response to exercise in athletes: dysmetabolism or altered autonomic nervous system modulation?
    Julie Turmel
    Quebec Heart and Lung Institute Research Center, Faculty of Pharmacy, Laval University, Quebec, Canada
    Blood Press Monit 17:184-92. 2012
    ..The importance of exercise-induced exaggerated blood pressure (BP) response in endurance athletes is not known...
  54. doi request reprint Increased plasma interleukin-1 receptor antagonist levels in men with visceral obesity
    Amélie Cartier
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Sainte Foy, Quebec, QC, Canada
    Ann Med 41:471-8. 2009
    ..Adipose tissue (AT) is an important source of interleukin-1 receptor antagonist (IL-1Ra). Its expression is markedly increased in obesity...
  55. pmc Low serum magnesium concentrations are associated with a high prevalence of premature ventricular complexes in obese adults with type 2 diabetes
    Liana C Del Gobbo
    School of Dietetics and Human Nutrition, McGill University, 21, 111 Lakeshore Road, Ste Anne de Bellevue, Quebec, H9X 3V9, Canada
    Cardiovasc Diabetol 11:23. 2012
    ..We thus hypothesized that serum magnesium (sMg) concentrations are inversely associated with the prevalence of PVC in adults at high cardiovascular risk...
  56. doi request reprint Low cardiorespiratory fitness levels and elevated blood pressure: what is the contribution of visceral adiposity?
    Caroline Rheaume
    Department of Family and Emergency Medicine, Universite Laval, Quebec, Canada
    Hypertension 54:91-7. 2009
    ..Individuals with high visceral adipose tissue levels have higher blood pressure, independent of their fitness. Visceral adipose tissue may represent an important clinical target in the management of elevated blood pressure...
  57. doi request reprint Interrelationships between changes in anthropometric variables and computed tomography indices of abdominal fat distribution in response to a 1-year physical activity-healthy eating lifestyle modification program in abdominally obese men
    Nicole Villeneuve
    a Centre de recherche de l Institut universitaire de cardiologie et de pneumologie de Québec, Pavilion Marguerite D Youville, 2725 Chemin Ste Foy, Québec QC G1V 4G5, Canada
    Appl Physiol Nutr Metab 39:503-11. 2014
    ..The 1-year lifestyle modification program therefore improved the body fat distribution pattern and midthigh muscle quality in abdominally obese men. ..
  58. ncbi request reprint Elevated peak exercise systolic blood pressure is not associated with reduced exercise capacity in subjects with Type 2 diabetes
    Patrice Brassard
    Institut Universitaire de Cardiologie et de Pneumologie, Centre de Recherche l Hôpital Laval, Sainte Foy, Quebec, Canada G1V 4G5
    J Appl Physiol 101:893-7. 2006
    ....
  59. pmc A most unusual acute coronary syndrome
    C Bourgault
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Hopital Laval, Sainte Foy, Canada
    Can J Cardiol 22:429-32. 2006
    ..Coronary vasospasm was attributed to serotonin, which was secreted by the carcinoid tumour that reached an atherosclerotic coronary vasculature through a patent foramen ovale, thereby avoiding pulmonary inactivation...
  60. ncbi request reprint The effect of implementation intentions on physical activity among obese older adults: a randomised control study
    Ariane Bélanger-Gravel
    Department of Social and Preventive Medicine, Laval University, Quebec City, Canada
    Psychol Health 28:217-33. 2013
    ..Physical activity is a key factor for healthy ageing and obesity management. The aim of this study was to test the effect of implementation intentions (IIs) on physical activity and body weight among inactive obese older adults...
  61. ncbi request reprint Improvement in insulin sensitivity following a 1-year lifestyle intervention program in viscerally obese men: contribution of abdominal adiposity
    Anne Laure Borel
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, QC, Canada
    Metabolism 61:262-72. 2012
    ..Changes in SAT and VAT but not in CRF appeared to mediate these improvements...
  62. ncbi request reprint The benefit of aspirin therapy in type 2 diabetes: what is the evidence?
    Caroline Sirois
    Faculte de Pharmacie, Universite Laval, Quebec, Canada
    Int J Cardiol 129:172-9. 2008
    ....
  63. pmc The influence of CYP2D6 phenotype on the clinical response of nebivolol in patients with essential hypertension
    Jean Lefebvre
    Hypertension Research Unit, CHUL Research Center, Faculty of Pharmacy, Laval University, Quebec, Canada
    Br J Clin Pharmacol 63:575-82. 2007
    ..The metabolism of the third-generation beta(1)-receptor antagonist nebivolol has been shown to be highly dependent on cytochrome P450 2D6 enzymatic activity in preclinical studies...
  64. doi request reprint Safety of laparoscopic vs open bariatric surgery: a systematic review and meta-analysis
    Jennifer Reoch
    Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital McGill University, Quebec, Canada
    Arch Surg 146:1314-22. 2011
    ....
  65. ncbi request reprint Influence of n-3 fatty acids on cardiac autonomic activity among Nunavik Inuit adults
    Beatriz Valera
    Axe Santé des Populations et Environnement, Centre de recherche du CHUQ, Quebec, QC G1V 2M2, Canada
    Int J Circumpolar Health 70:6-18. 2011
    ..The study assessed the impact of n-3 PUFAs (Docosahexaenoic [DHA] and Eicosapentaenoic acid [EPA]) on resting HR and HRV among Nunavik Inuit adults considering mercury and other potential confounders...
  66. doi request reprint Persistence patterns with oral antidiabetes drug treatment in newly treated patients--a population-based study
    Jean Pierre Grégoire
    Faculty of Pharmacy, Universite Laval, Quebec, QC, Canada
    Value Health 13:820-8. 2010
    ..We assessed persistence patterns with oral antidiabetes drug (OAD) in patients newly dispensed with different OAD classes...
  67. pmc Skeletal muscle endurance and muscle metabolism in patients with chronic heart failure
    Patrice Brassard
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Universite Laval, Ste Foy, Quebec, Canada
    Can J Cardiol 22:387-92. 2006
    ..Alterations in skeletal muscle function are known to contribute to exercise intolerance in patients with chronic heart failure (CHF)...
  68. ncbi request reprint Comparison between arterial and venous sampling of circulating hormones, substrates and peptides in severe obesity
    Julie Martin
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725 Chemin Ste Foy, Quebec, QC, Canada
    Clin Invest Med 34:E82-7. 2011
    ..The comparability of a given sample site (arterial vs. venous) with regards to blood parameters is yet to be established...
  69. doi request reprint A simple Doppler echocardiography method to evaluate pulmonary capillary wedge pressure in patients with atrial fibrillation
    Mario Senechal
    Quebec Heart Institute, Laval Hospital, Quebec, Canada
    Echocardiography 25:57-63. 2008
    ....
  70. ncbi request reprint Hypertension among the Inuit from Nunavik: should we expect an increase because of obesity?
    Marie Ludivine Chateau-Degat
    School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, Canada
    Int J Circumpolar Health 69:361-72. 2010
    ..This study aimed to assess the exact prevalence of HTN in Nunavik Inuit and to examine its association with other major risk factors of cardiovascular disease...
  71. ncbi request reprint Identifying which patients with diabetes should be tested for the presence of coronary artery disease--the importance of baseline electrocardiogram and exercise testing
    Paul Poirier
    Institut Universitaire de Cardiologie et de Pneumologie, Hopital Laval, Ste Foy, Quebec
    Can J Cardiol 22:9A-15A. 2006
    ..The present paper reviews some clinical markers that may be helpful to the clinician to increase the yield of finding significant occult CAD while screening patients with diabetes...
  72. pmc Ezetimibe-associated myopathy in monotherapy and in combination with a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
    Chantale Simard
    Centre de Recherche, Hopital Laval, Universite Laval, Sainte Foy, Quebec, Canada
    Can J Cardiol 22:141-4. 2006
    ..These cases suggest that ezetimibe monotherapy as well as ezetimibe associated with the use of a statin may induce myalgia. The mechanism by which ezetimibe could cause muscle pain is not known...
  73. ncbi request reprint Impact of waist circumference on the relationship between blood pressure and insulin: the Quebec Health Survey
    Paul Poirier
    Quebec Heart and Lungs Institute, Laval Hospital Research Center, Quebec, Canada
    Hypertension 45:363-7. 2005
    ..3%; P<0.0001). These results suggest that the documented association between obesity, fasting insulin, insulin sensitivity, and blood pressure is largely explained by concomitant variation in WC...
  74. ncbi request reprint Very late in-stent restenosis (five years) presenting as an ST elevation acute myocardial infarction
    Olivier F Bertrand
    Quebec Heart Lung Institute, Laval Hospital, 2725 Chemin Ste Foy, Quebec City, Quebec G1V 4G5, Canada
    Can J Cardiol 20:1481-3. 2004
    ..The patient underwent uneventful repeat stenting. Late in-stent restenosis may present as an intrastent plaque rupture with a clinical presentation similar to an atherosclerotic plaque rupture...
  75. ncbi request reprint A randomized study comparing same-day home discharge and abciximab bolus only to overnight hospitalization and abciximab bolus and infusion after transradial coronary stent implantation
    Olivier F Bertrand
    Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, affilié à l Université Laval, 2725 Chemin Ste Foy, Quebec, Canada G1V 4G5
    Circulation 114:2636-43. 2006
    ..It is unknown whether moderate- and high-risk patients can be discharged safely the same day after uncomplicated transradial percutaneous coronary interventions...
  76. ncbi request reprint [Obesity and cardiovascular disease]
    Paul Poirier
    Institut Universitaire de Cardiologie et de Pneumologie, Centre de Recherche de l Hopital Laval, 2725, Chemin Sainte Foy, Sainte Foy, Quebec, G1V 4G5, Canada
    Med Sci (Paris) 19:943-9. 2003
    ....
  77. ncbi request reprint Effect of atorvastatin on exercise-induced myocardial ischemia in patients with stable angina pectoris
    Peter Bogaty
    Quebec Heart Institute, Laval Hospital, Ste Foy, Quebec, Canada
    Am J Cardiol 92:1192-5. 2003
    ..Endothelial function improved progressively and C-reactive protein, P-selectin, and tissue plasminogen activator inhibitor levels decreased, but there was no decrease in exercise electrocardiographic ischemia...
  78. ncbi request reprint Impact of diet-induced weight loss on the cardiac autonomic nervous system in severe obesity
    Paul Poirier
    Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Health Sciences Center, Denver, Colorado, USA
    Obes Res 11:1040-7. 2003
    ....
  79. ncbi request reprint What induces the warm-up ischemia/angina phenomenon: exercise or myocardial ischemia?
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, 2725 Chemin Ste Foy, Ste Foy, Quebec, Canada G1V 4G5
    Circulation 107:1858-63. 2003
    ....
  80. ncbi request reprint Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss
    Paul Poirier
    Quebec Heart and Lung Institute, Sainte Foy, Canada
    Arterioscler Thromb Vasc Biol 26:968-76. 2006
    ..As a whole, overweight/obesity predispose or is associated with numerous cardiac complications such as coronary heart disease, heart failure, and sudden death through its impact on the cardiovascular system...
  81. ncbi request reprint [Impact of obesity in contemporary cardiology]
    Paul Poirier
    Institut Universitaire de Cardiologie et de Pneumologie, Centre de recherche de I Hôpital Laval, 2725, Chemin Sainte Foy, Sainte Foy Québec, G1V 4G5, Canada
    Med Sci (Paris) 21:3-9. 2005
    ....
  82. pmc Cardiac autonomic activity and blood pressure among Nunavik Inuit adults exposed to environmental mercury: a cross-sectional study
    Beatriz Valera
    Public Health Research Unit, 2875 boulevard Laurier, Edifice Delta 2, bureau 600, G1V 2M2, Quebec QC, Canada
    Environ Health 7:29. 2008
    ..MeHg has been suggested to affect BP in adults and children while the influence on HRV has only been studied in children. We aimed to assess the impact of MeHg levels on HRV and BP in Inuit adults from Nunavik...
  83. ncbi request reprint Impact of moderate aerobic exercise training on insulin sensitivity in type 2 diabetic men treated with oral hypoglycemic agents: is insulin sensitivity enhanced only in nonobese subjects?
    Paul Poirier
    Quebec Heart Institute Laval Hospital, 2725 Chemin Sainte Foy, Sainte Foy, Quebec, Canada G1V 4G5
    Med Sci Monit 8:CR59-65. 2002
    ..Most studies that involved nonobese subjects showed enhanced insulin sensitivity whereas studies involving obese subjects with type 2 diabetes are inconsistent because of concomitant fat loss...
  84. ncbi request reprint Effects of intracoronary compared to intravenous abciximab administration in patients undergoing transradial percutaneous coronary intervention: A sub-analysis of the EASY trial
    Olivier F Bertrand
    Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Canada
    Int J Cardiol 136:165-70. 2009
    ..We sought to compare cardiac biomarkers release and early and late clinical outcomes after IC or IV abciximab bolus delivery...
  85. pmc Targeting abdominal obesity in cardiology: can we be effective?
    Paul Poirier
    Laval University, Laval Hospital, Sainte Foy, Quebec
    Can J Cardiol 24:13D-17D. 2008
    ....
  86. ncbi request reprint Predictors of compliance with medical recommendations regarding pharmacological and non pharmacological approaches in patient with cardiovascular disease
    Paul Poirier
    Institut Universitaire de Cardiologie et de Pneumologie, Hopital Laval, Ste Foy, Quebec, Canada
    Clin Invest Med 29:91-103. 2006
  87. doi request reprint Contributions of cardiorespiratory fitness and visceral adiposity to six-year changes in cardiometabolic risk markers in apparently healthy men and women
    Caroline Rheaume
    Department of Family and Emergency Medicine, Faculty of Medicine, Universite Laval, Quebec, Canada G1V 0A6
    J Clin Endocrinol Metab 96:1462-8. 2011
    ..Both excess visceral adipose tissue (VAT) and low cardiorespiratory fitness (CRF) levels are associated with a deteriorated cardiometabolic risk profile...
  88. doi request reprint Obesity, adiposity indices, and blood pressure; ethnicity does matter
    Paul Poirier
    Department of Cardiology Institut universitaire de cardiologie et de pneumologie, Laval Hospital Research Center, Quebec, Canada
    Am J Hypertens 21:244. 2008
  89. ncbi request reprint Comparison of diagnostic criteria of the metabolic syndrome in 3 ethnic groups of Canada
    Marie Ludivine Chateau-Degat
    Centre for Indigenous Peoples Nutrition and Environment and School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, Quebec, Canada H9X 3V9
    Metabolism 57:1526-32. 2008
    ..001). These 3 unique population-based samples suggest that abdominal obesity does not have a similar deleterious impact according to ethnicity, suggesting the need for an ethnic-based MetS definition...
  90. doi request reprint Cardiac arrest as a major complication of bilateral cervico-dorsal sympathectomy
    Kim O'Connor
    Department of Cardiology, Institut Universitaire de Cardiologie et de Pneumologie, Hopital Laval, Quebec, Canada
    Interact Cardiovasc Thorac Surg 8:238-9. 2009
    ..The cardiovascular effects of cervico-dorsal sympathectomy will be reviewed. Evaluation required to prevent such a serious cardiac complication will also be discussed...
  91. ncbi request reprint Impact of bariatric surgery on cardiac structure, function and clinical manifestations in morbid obesity
    Paul Poirier
    Department of Cardiology, Institut Universitaire de Cardiologie et de Pneumologie, Laval Hospital, 2725 Chemin Sainte Foy, Sainte Foy, Quebec, G1V 4G5, Canada
    Expert Rev Cardiovasc Ther 2:193-201. 2004
    ..Nevertheless, numerous different techniques are still in use today. Weight loss has beneficial impacts on functional and structural cardiac status and will be reviewed in this report...
  92. doi request reprint Reduced heart rate variability in patients with chronic obstructive pulmonary disease independent of anticholinergic or β-agonist medications
    Marie Eve Bédard
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    COPD 7:391-7. 2010
    ..These results demonstrate that COPD patients have a reduced sympatho-vagal balance compared with healthy subjects. HRV correlates with disease severity and does not seem to be influenced by anticholinergic or adrenergic medications...