Research Topics
| S PerreaultSummaryCountry: Canada Publications
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Publications
Trends and determinants of antiresorptive drug use for osteoporosis among elderly womenSylvie Perreault
Faculty of Pharmacy, University of Montreal, Montreal, Que, Canada
Pharmacoepidemiol Drug Saf 14:685-95. 2005..The objective is to estimate the rate ratio (RR) of having an ART prescription filled among elderly women and its relation to selected determinants from 1995 through 2001...
Validation of a decision model for preventive pharmacological strategies in postmenopausal womenSylvie Perreault
Faculty of Pharmacy, University of Montreal, Quebec, Canada
Eur J Epidemiol 20:89-101. 2005....
Persistence with treatment in newly treated middle-aged patients with essential hypertensionSylvie Perreault
Faculty of Pharmacy, University of Montreal, Quebec, Canada
Ann Pharmacother 39:1401-8. 2005..Surveys have shown that hypertension has been diagnosed in many patients but remains uncontrolled. One factor may be the lack of persistence to treatment...
Continuity of care in the ambulatory treatment of adolescents with asthmaMarie-Christyne Cyr
Faculty of Pharmacy, University of Montreal, Montreal, , Canada
J Adolesc Health 39:926.e11-7. 2006..Only the RxICC was associated with the risk of hospitalization and ED visits for asthma...
Effect of statin adherence on cerebrovascular disease in primary preventionSylvie Perreault
Faculty of Pharmacy, University of Montreal, Quebec, Canada
Am J Med 122:647-55. 2009..Nonadherence to statins may reduce this protective effect. The association between statin adherence and incidence of cerebrovascular disease remains unexplored outside the context of clinical trials...
Adherence to antihypertensive agents after ischemic stroke and risk of cardiovascular outcomesSylvie Perreault
Faculty of Pharmacy, University of Montreal, Faculty of Medicine, McGill University, Montreal, Canada
Neurology 79:2037-43. 2012..To evaluate the relationship between antihypertensive (AH) drug adherence and cardiovascular (CV) outcomes among patients with a recent ischemic stroke and assess the validity of our approach...
Ideal and actual involvement of community pharmacists in health promotion and prevention: a cross-sectional study in Quebec, CanadaMarie Claude Laliberté
Universite de Montreal, CP 6128, Succ Centre Ville, Montreal, Quebec H3C 3J7, Canada
BMC Public Health 12:192. 2012....
Prescription channeling of COX-2 inhibitors and traditional nonselective nonsteroidal anti-inflammatory drugs: a population-based case-control studyYola Moride
Faculty of Pharmacy, Universite de Montreal, Montreal, Canada
Arthritis Res Ther 7:R333-42. 2005..At the time of introduction of COX-2 inhibitors into the formulary, prescription channeling could confound risk comparisons across products...
Population-based study of the effectiveness of bone-specific drugs in reducing the risk of osteoporotic fractureSylvie Perreault
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Pharmacoepidemiol Drug Saf 17:248-59. 2008..But treatment rates for osteoporosis among high-risk patients are far below the recommended guidelines. A major concern about BSDs is the lack of adherence with treatment...
Better adherence to antihypertensive agents and risk reduction of chronic heart failureS Perreault
Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada
J Intern Med 266:207 - 18. 2009..However, the impact of changes in patterns of AH agents use on CHF is unknown. Our objective was to estimate to which different patterns of AH agent use is associated with the occurrence of CHF in a population-based study...
Impact of adherence to statins on chronic heart failure in primary preventionSylvie Perreault
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Br J Clin Pharmacol 66:706-16. 2008..Our aim was to evaluate the impact of adherence to statins on the incidence of CHF...
Impact of better adherence to statin agents in the primary prevention of coronary artery diseaseSylvie Perreault
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Eur J Clin Pharmacol 65:1013-24. 2009..Statins reduce cardiovascular morbidity and mortality after continuous treatment. Studies have shown that less than 50% of patients take 80% or more of prescribed doses 1 year after starting therapy...
Adherence level of antihypertensive agents in coronary artery diseaseSylvie Perreault
Faculties of Pharmacy and Medicine, University of Montreal, Montreal, Quebec, Canada
Br J Clin Pharmacol 69:74-84. 2010....
Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular diseaseSylvie Perreault
Faculty of Pharmacy, University of Montreal, P O Box 6128, Centre Ville Station, Montreal, Quebec, Canada, H3C 3J7
Eur J Clin Pharmacol 61:667-74. 2005..Objective. To evaluate the persistence rate of middle-aged patients initiating statin therapy as well as its relation to patients' demographic and clinical characteristics...
Persistence and determinants of statin therapy among middle-aged patients for primary and secondary preventionS Perreault
Faculty of Pharmacy, University of Montreal, Montreal, Quebec H3C 3J7, Canada
Br J Clin Pharmacol 59:564-73. 2005..The objective was to evaluate the persistence rate of middle-aged patients initiating a statin therapy and its relation with several determinants for primary and secondary prevention...
Pharmacokinetics of morphine and its glucuronidated metabolites in burn injuriesS Perreault
Faculty of Pharmacy, University of Montreal, PO Box 6128, Succ Centre Ville, Montreal, Quebec H3C 3J7, Canada
Ann Pharmacother 35:1588-92. 2001....
Impact of adherence to statins on coronary artery disease in primary preventionMarie Hélène Bouchard
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Br J Clin Pharmacol 63:698-708. 2007..Studies have shown that <40% of patients take > or =80% of prescribed doses 1 year after starting therapy and that approximately half discontinue medication within 6 months of starting therapy...
Changes in pattern of use, clinical characteristics and persistence rate of hormone replacement therapy among postmenopausal women after the WHI publicationMarie Pascale Guay
Faculty of Pharmacy, University of Montreal, Montreal, Canada
Pharmacoepidemiol Drug Saf 16:17-27. 2007..The WHI was stopped prematurely because of an increased risk of breast cancer, stroke and cardiovascular diseases (CVD) in the hormone replacement therapy (HRT) arm of the trial. Changes in the use of HRT are expected...
Impact of a better adherence to antihypertensive agents on cerebrovascular disease for primary preventionFatima Zohra Kettani
Faculty of Pharmacy, PO Box 6128, Centre Ville Station, Montreal, Quebec, Canada
Stroke 40:213-20. 2009..The purpose of this study was to assess the impact of adherence to AH agents on the incidence of cerebrovascular disease (CD) in real-world practice...
Impact of adherence to antihypertensive agents on clinical outcomes and hospitalization costsAlice Dragomir
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Med Care 48:418-25. 2010..Low adherence to antihypertensive (AH) agents is acknowledged as a major contributor to the lack of blood pressure control, and may have a significant impact on clinical outcomes and healthcare costs...
Effectiveness of interventions to improve the detection and treatment of osteoporosis in primary care settings: a systematic review and meta-analysisM C Laliberté
Faculty of Pharmacy, Universite de Montreal, Montreal, QC, Canada
Osteoporos Int 22:2743-68. 2011..Multifaceted interventions targeting high-risk patients and their primary care providers may improve the management of osteoporosis, but improvements are often clinically modest...
Comparison of persistence rates with angiotensin-converting enzyme inhibitors used in secondary and primary prevention of cardiovascular diseaseAmede Gogovor
University of Montreal, Montreal, QC, Canada
Value Health 10:431-41. 2007..To measure and compare persistence rates with the angiotensin-converting enzyme inhibitors (ACEIs) in primary and secondary prevention and their determinants...
Impact of a primary care physician workshop on osteoporosis medical practicesM C Laliberté
Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada
Osteoporos Int 21:1471-85. 2010..However, osteoporosis management remained sub-optimal, particularly in men...
Control and severity of asthma during pregnancy are associated with asthma incidence in offspring: two-stage case-control studyM J Martel
Universite de Montreal, QC, Canada
Eur Respir J 34:579-87. 2009....
Isotretinoin, pregnancies, abortions and birth defects: a population-based perspectiveAnick Berard
Faculty of Pharmacy, University of Montreal, CHU Sainte Justine, Montreal, QC, Canada
Br J Clin Pharmacol 63:196-205. 2007..To estimate the population-based incidence rates of pregnancy, spontaneous and elective abortions, and birth defects associated with isotretinoin use, and to determine predictors of pregnancy while on isotretinoin...
Relationship between adherence level to statins, clinical issues and health-care costs in real-life clinical settingAlice Dragomir
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Value Health 13:87-94. 2010..Low adherence to statins may have a significant impact on clinical issues and health-care costs. The objective is to evaluate the impact of low adherence to statins on clinical issues and direct health-care costs...
Maternal asthma, its control and severity in pregnancy, and the incidence of atopic dermatitis and allergic rhinitis in the offspringMarie Josée Martel
Faculty of Pharmacy, Universite de Montreal, Montreal, Quebec, Canada
J Pediatr 155:707-13.e1. 2009..To evaluate the relationship between maternal asthma, its level of control and severity during pregnancy, and atopic dermatitis (AD) and allergic rhinitis (AR) incidence in children...
A cluster randomized controlled Trial to Evaluate an Ambulatory primary care Management program for patients with dyslipidemia: the TEAM studyJulie Villeneuve
Faculties of Pharmacy, Universite de Montreal, Montreal, Que
CMAJ 182:447-55. 2010..Few studies have reported the efficacy of collaborative care involving family physicians and community pharmacists for patients with dyslipidemia...
Determinants of the incidence of childhood asthma: a two-stage case-control studyMarie Josée Martel
Faculty of Pharmacy, Universite de Montreal, Montreal, Quebec, Canada
Am J Epidemiol 169:195-205. 2009..This study allowed the authors to identify, within a single setting, the most influential determinants of childhood asthma among 47 predictors assessed for the prenatal, perinatal, and childhood periods...
Is long-term pharmacist-managed anticoagulation service efficient? A pragmatic randomized controlled trialLyne Lalonde
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Am Heart J 156:148-54. 2008..This may be as effective as and less expensive than long-term PMAS follow-up...
Economic impact of Tibolone compared with Continuous-Combined Hormone Replacement Therapy in the management of climacteric symptoms in postmenopausal womenVakaramoko Diaby
Faculty of Pharmacy, University of Montreal, Centre Ville, Montreal, QC H3C 3J7, Canada
Maturitas 58:138-49. 2007..It has been used in Europe, in the same indication as CCHRT, for approximately 20 years but is not yet available in Canada...
Exposure to anti-infective drugs during pregnancy and the risk of small-for-gestational-age newborns: a case-control studyF Santos
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada
BJOG 118:1374-82. 2011..To determine the association between anti-infective exposure during the last two trimesters of pregnancy and the risk of small-for-gestational-age (SGA) newborns...
Discontinuation of antiresorptive therapies: a comparison between 1998-2001 and 2002-2004 among osteoporotic womenJulie Blouin
Faculty, University of Montreal, Montreal, Quebec, Canada H3C 3J7
J Clin Endocrinol Metab 92:887-94. 2007..Studies having reported high rates of discontinuation of antiresorptive therapies (ART) may not reflect their actual use...
Efficacy and costs of patient-controlled analgesia versus regularly administered intramuscular opioid therapyM Choiniere
Department of Anesthesia, Faculty of Medicine, University of Montreal, Quebec, Canada
Anesthesiology 89:1377-88. 1998..The current study was designed to evaluate these issues by comparing PCA with regularly administered intramuscular injections of opioids after hysterectomy...
Comparison of direct health care costs related to the pharmacological treatment of osteoporosis and to the management of osteoporotic fractures among compliant and noncompliant users of alendronate and risedronate: a population-based studyJ Blouin
Faculty of Pharmacy, University of Montreal, PO Box 6128, Centre Ville Station, Montreal, Quebec, Canada, H3C 3J7
Osteoporos Int 20:1571-81. 2009..During a 2-year follow-up period, compared to those with medication possession ratio (MPR) > or = 80%, women with MPR < 80% incurred significantly higher physician care costs and hospital care costs...
Intraoperative floppy-iris syndrome associated with alpha1-adrenoreceptors: comparison of tamsulosin and alfuzosinMarie Claude Blouin
Department of Ophthalmology, University of Sherbrooke, Campus Chicoutimi, Montreal, Quebec, Canada
J Cataract Refract Surg 33:1227-34. 2007..To compare the incidence of intraoperative floppy-iris syndrome (IFIS) in men exposed to tamsulosin and men exposed to alfuzosin and evaluate the effect of IFIS on the complication rate of cataract surgery...
Efficacy and cost of HMG-CoA reductase inhibitors in the treatment of patients with primary hyperlipidemiaS Perreault
University of Montreal, Montreal, Canada
Can J Clin Pharmacol 7:144-54. 2000..The choice of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) and the dose level may have significant implications for both efficient and cost effective therapy...
Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control studyMarie Josée Martel
Faculty of Pharmacy, Universite de Montreal, CP 6128, Succursale Centre Ville, Montreal, QC, Canada H3C 3J7
BMJ 330:230. 2005..To determine whether the use of inhaled corticosteroids during pregnancy increases the risk of pregnancy induced hypertension and pre-eclampsia among asthmatic women...
Primary care practices and determinants of optimal anticoagulation management in a collaborative care modelKerby Maud Louis
Biomedical Science Department, Faculty of Medicine, University of Montreal, Montreal, Canada
Am Heart J 159:183-9. 2010..The objective of this study was to describe physicians' clinical practices and the practice characteristics associated with better international normalized ratio (INR) control in a CCM...
Persistence, adherence, and effectiveness of combination therapy among adult patients with asthmaClaudine Marceau
Faculty of Pharmacy, University of Montreal, Quebec, Canada
J Allergy Clin Immunol 118:574-81. 2006..CLINICAL IMPLICATIONS: Combination therapy might be preferred to concurrent therapy for patients with asthma with low adherence to controller therapies...
Effect of fetal gender on maternal asthma exacerbations in pregnant asthmatic womenFaranak Firoozi
Universite de Montreal, Quebec, Canada
Respir Med 103:144-51. 2009..23 to 0.24). Based on the results, we conclude that fetal gender is unlikely to affect maternal asthma during pregnancy to the point where acute care and medications are more often required among women pregnant with a female fetus...
Impact of noncompliance with alendronate and risedronate on the incidence of nonvertebral osteoporotic fractures in elderly womenJulie Blouin
Faculties of Pharmacy, University of Montreal, Montreal, Quebec, Canada
Br J Clin Pharmacol 66:117-27. 2008..To evaluate the association between noncompliance with alendronate and risedronate and the risk of nonvertebral osteoporotic fracture in community-dwelling elderly women...
Use of short-acting beta2-agonists during pregnancy and the risk of pregnancy-induced hypertensionMarie Josée Martel
Universite de Montreal, C P 6128, Succursale Centre Ville, Montreal, Quebec H3C 3J7, Canada
J Allergy Clin Immunol 119:576-82. 2007..After the finding of a possible protective association of inhaled SABAs with pregnancy-induced hypertension (PIH) in a previous study, we decided to further investigate their effect on this condition...
Intrathecal morphine after cardiac surgeryAline Boulanger
Department of Anaesthesiology, Hôtel Dieu du Centre hospitalier de l Université de Montréal, Montreal, Quebec, Canada
Ann Pharmacother 36:1337-43. 2002..To assess whether intrathecal (IT) analgesia facilitates early extubation and provides superior pain control after cardiac surgery compared with patient-controlled analgesia (PCA) or nurse-administered SC injections...
Recommendations for the prevention of osteoporosis and fragility fractures. International comparison and synthesisMichel Rossignol
McGill University
Int J Technol Assess Health Care 18:597-610. 2002..A second compromise would be to recognize the complementary roles of public health and clinical professionals toward the common objective of preventing fragility fractures...
