S W Wen

Summary

Affiliation: Ottawa Health Research Institute
Country: Canada

Publications

  1. ncbi Fetal and neonatal mortality among twin gestations in a Canadian population: the effect of intrapair birthweight discordance
    Shi Wu Wen
    Health Surveillance and Epidemiology Division, Centre for Healthy Human Development, Health Canada, Ottawa, Ontario, Canada
    Am J Perinatol 22:279-86. 2005
  2. ncbi A comprehensive assessment of outcomes in pregnancies conceived by in vitro fertilization/intracytoplasmic sperm injection
    Shi Wu Wen
    Department of Obstetrics and Gynecology, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada
    Eur J Obstet Gynecol Reprod Biol 150:160-5. 2010
  3. ncbi A pre-conception cohort to study preeclampsia in China: Rationale, study design, and preliminary results
    Shiwu Wen
    School of Public Health, Central South University, Changsha 410078, China OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada Ottawa Hospital Research Institute, Ottawa Ontario K1H 8L6, Canada Department of Epidemiology and Community Medicine, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 37:1081-7. 2012
  4. ncbi Secular trends in trial of labor and associated neonatal mortality and morbidity in the United States, 1995 to 2002
    Shiwu Wen
    Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa Ontario K1H 8L6, Canada Department of Epidemiology and Community Medicine, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada School of Public Health, Central South University, Changsha 410078, China
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 37:1088-96. 2012
  5. ncbi The impact of missing birth weight in deceased versus surviving fetuses and infants in the comparison of birth weight-specific feto-infant mortality
    Shi Wu Wen
    The Ottawa Hospital General Campus, 501 Smyth Road, Box 201, Ottawa, Ontario Canada K1H 8L6 fax 613 739 6266 e mail
    Chronic Dis Can 23:146-51. 2002
  6. ncbi Folic acid supplementation in early second trimester and the risk of preeclampsia
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 198:45.e1-7. 2008
  7. ncbi The association between fetal sex and preterm birth in twin pregnancies
    Hongzhuan Tan
    OMNI Research Group and Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, Ontario, Canada K1H 8L6
    Obstet Gynecol 103:327-32. 2004
  8. ncbi Occurrence and predictors of cesarean delivery for the second twin after vaginal delivery of the first twin
    Shi Wu Wen
    OMNI Research Group, Division of Maternal Fetal Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Obstet Gynecol 103:413-9. 2004
  9. ncbi Maternal morbidity and obstetric complications in triplet pregnancies and quadruplet and higher-order multiple pregnancies
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynecology and Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 191:254-8. 2004
  10. ncbi Severe maternal morbidity in Canada, 1991-2001
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynaecology, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ont
    CMAJ 173:759-64. 2005

Collaborators

Detail Information

Publications97

  1. ncbi Fetal and neonatal mortality among twin gestations in a Canadian population: the effect of intrapair birthweight discordance
    Shi Wu Wen
    Health Surveillance and Epidemiology Division, Centre for Healthy Human Development, Health Canada, Ottawa, Ontario, Canada
    Am J Perinatol 22:279-86. 2005
    ....
  2. ncbi A comprehensive assessment of outcomes in pregnancies conceived by in vitro fertilization/intracytoplasmic sperm injection
    Shi Wu Wen
    Department of Obstetrics and Gynecology, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada
    Eur J Obstet Gynecol Reprod Biol 150:160-5. 2010
    ..To assess the association between in vitro fertilization (IVF) with or without intracytoplasmic sperm injection (ICSI) and adverse birth outcomes...
  3. ncbi A pre-conception cohort to study preeclampsia in China: Rationale, study design, and preliminary results
    Shiwu Wen
    School of Public Health, Central South University, Changsha 410078, China OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada Ottawa Hospital Research Institute, Ottawa Ontario K1H 8L6, Canada Department of Epidemiology and Community Medicine, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 37:1081-7. 2012
    ..Conclusion: The proposed pre-conception cohort study will have important theoretical and practical implications on the prevention of PE and its associated cardiovascular disease risks...
  4. ncbi Secular trends in trial of labor and associated neonatal mortality and morbidity in the United States, 1995 to 2002
    Shiwu Wen
    Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa Ontario K1H 8L6, Canada Department of Epidemiology and Community Medicine, University of Ottawa, Faculty of Medicine, Ottawa Ontario K1H 8L6, Canada School of Public Health, Central South University, Changsha 410078, China
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 37:1088-96. 2012
    ..Conclusion: The reduced use of trial of labor after one cesarean delivery in recent years in the United States has actually resulted in increased risk of adverse neonatal outcomes associated with a trial of labor...
  5. ncbi The impact of missing birth weight in deceased versus surviving fetuses and infants in the comparison of birth weight-specific feto-infant mortality
    Shi Wu Wen
    The Ottawa Hospital General Campus, 501 Smyth Road, Box 201, Ottawa, Ontario Canada K1H 8L6 fax 613 739 6266 e mail
    Chronic Dis Can 23:146-51. 2002
    ..The authors concluded that differences in missing birth weight information between deaths and survivors can bias comparisons of birth weight-specific feto-infant mortality...
  6. ncbi Folic acid supplementation in early second trimester and the risk of preeclampsia
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 198:45.e1-7. 2008
    ..The objective of the study was to evaluate the association between folic acid supplementation in early second trimester and the risk of developing preeclampsia...
  7. ncbi The association between fetal sex and preterm birth in twin pregnancies
    Hongzhuan Tan
    OMNI Research Group and Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, Ontario, Canada K1H 8L6
    Obstet Gynecol 103:327-32. 2004
    ..To assess the association between the fetal sex and preterm birth...
  8. ncbi Occurrence and predictors of cesarean delivery for the second twin after vaginal delivery of the first twin
    Shi Wu Wen
    OMNI Research Group, Division of Maternal Fetal Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Obstet Gynecol 103:413-9. 2004
    ..To estimate the occurrence and to assess clinical predictors of emergent cesarean delivery in the second twin after vaginal delivery of the first twin...
  9. ncbi Maternal morbidity and obstetric complications in triplet pregnancies and quadruplet and higher-order multiple pregnancies
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynecology and Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 191:254-8. 2004
    ..The purpose of this study was to assess the risk of maternal morbidity and obstetric complications in women with triplet pregnancies and quadruplet and higher-order multiple pregnancies...
  10. ncbi Severe maternal morbidity in Canada, 1991-2001
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynaecology, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ont
    CMAJ 173:759-64. 2005
    ..Our purpose in this study was to describe severe maternal morbidity in Canada over a 10-year period, among women with or without major pre-existing conditions...
  11. ncbi Neonatal morbidity in second twin according to gestational age at birth and mode of delivery
    Shi Wu Wen
    OMNI Research Group, Division of Maternal Fetal Medicine, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 191:773-7. 2004
    ..This study was undertaken to assess the risk of neonatal morbidity in the second twins...
  12. ncbi Neonatal mortality in second twin according to cause of death, gestational age, and mode of delivery
    Shi Wu Wen
    OMNI Research Group, Division of Maternal Fetal Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 191:778-83. 2004
    ..The purpose of this study was to assess the risk of neonatal death in the second twin...
  13. ncbi Comparison of maternal mortality and morbidity between trial of labor and elective cesarean section among women with previous cesarean delivery
    Shi Wu Wen
    Division of Health Surveillance and Epidemiology, Centre for Healthy Human Development, Health Canada, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Am J Obstet Gynecol 191:1263-9. 2004
    ..This study was undertaken to assess the safety of trial of labor after previous cesarean delivery...
  14. ncbi Prediction of small for gestational age by logistic regression in twins
    Shi Wu Wen
    School of Public Health, Central South University, Changsha, China
    Aust N Z J Obstet Gynaecol 45:399-404. 2005
    ..The reported methods of SGA prediction are not satisfactory because the diagnostic performance is poor and the interval between prediction and delivery is too short...
  15. ncbi The association between intratwin birthweight discordance and preterm birth in twin pregnancy
    Shi Wu Wen
    School of Public Health, Central South University, Changsha, Hunan, China
    Aust N Z J Obstet Gynaecol 46:402-6. 2006
    ....
  16. ncbi Prediction of intra-twin birth weight discordance by binary logistic regression analysis
    Shi Wu Wen
    School of Public Health, Central South University, Changsha, Hunan, PR China
    Gynecol Obstet Invest 62:186-92. 2006
    ..Identification of women at high risk of intra-twin birth weight discordance is helpful in obstetric care of these pregnancies. The aim of this study is to establish an intra-twin birth weight discordance prediction model...
  17. ncbi Epidemiology of preterm birth and neonatal outcome
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ontario, Canada
    Semin Fetal Neonatal Med 9:429-35. 2004
    ..Future research should concentrate on the ways to reduce long-term health sequelae and developmental handicaps among survivors of infants born preterm, as well as elucidating the mechanisms and aetiology of preterm births...
  18. ncbi Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population
    S W Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada
    J Perinatol 28:324-9. 2008
    ..To examine prescription Food and Drug Administration (FDA) C, D and X drugs in general obstetric population...
  19. ncbi Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes
    Shi Wu Wen
    University of Ottawa, Ont, Canada
    CMAJ 179:1263-8. 2008
    ..The objective of the current study was to assess the possible effects of using folic acid antagonists in pregnancy on placenta-mediated adverse outcomes of pregnancy...
  20. ncbi Secular trends of fetal growth in Canada, 1981 to 1997
    Shi Wu Wen
    Department of Obstetrics and Gynecology and Clinical Epidemiology Program, University of Ottawa, Ontario, Canada
    Paediatr Perinat Epidemiol 17:347-54. 2003
    ..We conclude that Canadian infants are getting bigger, but only those born at term. The temporal trends for more extremely distributed fetal growth measures are particularly marked...
  21. ncbi Selective serotonin reuptake inhibitors and adverse pregnancy outcomes
    Shi Wu Wen
    Department of Obstetrics and Gynecology, University of Ottawa Faculty of Medicine, Canada
    Am J Obstet Gynecol 194:961-6. 2006
    ..The purpose of this study was to assess the safety of the use of selective serotonin reuptake inhibitors in pregnancy...
  22. ncbi Neonatal mortality and morbidity in vertex-vertex second twins according to mode of delivery and birth weight
    Q Yang
    OMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, and Ottawa Health Research Institute, Ottawa, Canada
    J Perinatol 26:3-10. 2006
    ..To assess the risk of neonatal mortality and morbidity in vertex-vertex second twins according to mode of delivery and birth weight...
  23. ncbi Gestational age- and birthweight-specific declines in infant mortality in Canada, 1985-94. Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System
    K S Joseph
    Bureau of Reproductive and Child Health, Laboratory Centre for Disease Control, Ottawa, Canada
    Paediatr Perinat Epidemiol 14:332-9. 2000
    ..Temporal changes in the outcome of post-term pregnancies need to be carefully examined, especially in relation to recent changes in the obstetric management of such pregnancies...
  24. ncbi Pregnancy-induced hypertension and infant mortality in triplets
    X K Chen
    Clinical Epidemiology Program, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    Int J Gynaecol Obstet 98:10-4. 2007
    ..To assess the effects of pregnancy-induced hypertension on infant mortality in triplets stratified by gestational age at birth...
  25. ncbi Comparison of maternal and infant outcomes between vacuum extraction and forceps deliveries
    S W Wen
    Bureau of Reproductive and Child Health, Centre for Healthy Human Development, Health Canada, Ottawa, Ontario
    Am J Epidemiol 153:103-7. 2001
    ..32, 2.70), respectively. The authors conclude that vacuum extraction causes less maternal trauma but may increase the risk of cephalhematoma and certain types of intracranial hemorrhage (e.g., subarachnoid hemorrhage)...
  26. ncbi Association of caesarean delivery for first birth with placenta praevia and placental abruption in second pregnancy
    Q Yang
    OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, Ontario, Canada
    BJOG 114:609-13. 2007
    ..To quantify the risk of placenta praevia and placental abruption in singleton, second pregnancies after a caesarean delivery of the first pregnancy...
  27. ncbi Pregnancy-induced hypertension and infant mortality: Roles of birthweight centiles and gestational age
    X K Chen
    OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    BJOG 114:24-31. 2007
    ....
  28. ncbi Recent trends in fetal and infant outcomes following post-term pregnancies
    S W Wen
    The Bureau of Reproductive and Child Health, Centre for Healthy Human Development, Health Canada, Tunney s Pasture, AL 0701D, Ottawa, Ontario K1A OL2, Canada
    Chronic Dis Can 22:1-5. 2001
    ....
  29. ncbi Hepatitis C infection and survivals of liver transplant patients in Canada, 1997-2003
    Z Hong
    Blood Safety Survellance Division, Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario, Canada
    Transplant Proc 40:1466-70. 2008
    ..Liver transplantation is an important health and health care issue for Canadians. Very few studies have estimated the survival results among liver transplant patients infected with hepatitis C virus (HCV) in Canada...
  30. ncbi Placenta praevia and male sex at birth: results from a population-based study
    S W Wen
    Bureau of Reproductive and Child Health, Laboratory Center for Disease Control, Health Canada, Ottawa, Ontario, Canada
    Paediatr Perinat Epidemiol 14:300-4. 2000
    ..We conclude that pregnant women with male babies carry a higher risk of placenta praevia...
  31. ncbi The distribution of intra-twin birth weight discordance and its association with total twin birth weight, gestational age, and neonatal mortality
    Hongzhuan Tan
    OMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, Ont, Canada
    Eur J Obstet Gynecol Reprod Biol 121:27-33. 2005
    ..CONCLUSIONS: The prevalence of birth weight discordance > or =25% among twin pregnancies was 8.6%, which is associated with lower gestational age at delivery and higher neonatal mortality rates, and may represent a pathologic process...
  32. ncbi Secular trends in congenital anomaly-related fetal and infant mortality in Canada, 1985-1996
    S Liu
    Bureau of Reproductive and Child Health, Centre for Healthy Human Development, Health Canada, HPB Building 7, Tunney s Pasture AL 0701D, Ottawa, Ontario, Canada K1A OL2
    Am J Med Genet 104:7-13. 2001
    ..These changes suggest an increase in prenatal diagnosis and selective termination of pregnancies with congenital anomalies in recent years...
  33. ncbi Impact of prenatal glucose screening on the diagnosis of gestational diabetes and on pregnancy outcomes
    S W Wen
    Bureau of Reproductive and Child Health, Health Canada, Ottawa, Ontario
    Am J Epidemiol 152:1009-14; discussion 1015-6. 2000
    ..The authors concluded that the substantial increase in gestational diabetes in Canada is an artifact caused by universal screening, with no evidence of beneficial effects on pregnancy outcomes...
  34. ncbi Pregnancy-induced hypertension is associated with lower infant mortality in preterm singletons
    X K Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    BJOG 113:544-51. 2006
    ..CONCLUSIONS: PIH is associated with lower risk of infant death in preterm births but higher risk in term births...
  35. ncbi Implausible birth weight for gestational age
    K S Joseph
    Bureau of Reproductive and Child Health, Laboratory Centre for Disease Control, Ottawa, Ontario, Canada
    Am J Epidemiol 153:110-3. 2001
    ..Current rules for identifying implausible birth weight for gestational age tend to flag live births at high risk for infant death. Such rules may erroneously attenuate temporal trends in important perinatal outcomes...
  36. ncbi Uterine contraction pattern as a predictor of the mode of delivery
    Lawrence W Oppenheimer
    Division of Perinatology, Ottawa General Hospital, Ottawa, Ontario, Canada
    J Perinatol 22:149-53. 2002
    ..A successful response to oxytocin augmentation may be predicted by the change in contraction pattern following treatment...
  37. ncbi Occurrence and clinical predictors of operative delivery for the vertex second twin after normal vaginal delivery of the first twin
    Qiuying Yang
    OMNI Research Group, Division of Maternal-Fetal Medicine, University of Ottawa, Faculty of Medicine, Canada
    Am J Obstet Gynecol 192:178-84. 2005
    ..3% and 8.3%, respectively, in vertex second twin after normal vaginal delivery of the first twin. The most important predictors for operative delivery are cord prolapse and fetal distress...
  38. ncbi Regional patterns of infant mortality caused by lethal congenital anomalies
    S W Wen
    Bureau of Reproductive and Child Health, Laboratory Centre for Disease Control, Ottawa, ON
    Can J Public Health 90:316-9. 1999
    ..To assess the regional patterns of infant mortality due to lethal congenital anomalies, and the potential reasons for the regional patterns...
  39. ncbi Birth cohort effects underlying the increasing testicular cancer incidence in Canada
    S Liu
    Bureau of Reproductive and Child Health, Laboratory Centre for Disease Control, Ottawa, ON
    Can J Public Health 90:176-80. 1999
    ..To examine the pattern of testicular cancer incidence by age, time period and birth cohort since 1969 in Canada...
  40. ncbi Patterns of infant mortality caused by major congenital anomalies
    S W Wen
    Bureau of Reproductive and Child Health, Laboratory Centre for Disease Control, Ottawa, Canada
    Teratology 61:342-6. 2000
    ..We assessed the impact of recent advances in perinatal care on infant mortality due to congenital anomaly...
  41. ncbi The relationship between cervical dilatation at initial presentation in labour and subsequent intervention
    P Holmes
    Division of Maternal-Fetal Medicine, Ottawa Hospital, University of Ottawa, ON, Canada
    BJOG 108:1120-4. 2001
    ..Outcomes were similar whether or not the woman was initially allowed home...
  42. ncbi Adverse maternal outcomes in multifetal pregnancies
    Mark C Walker
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa General Hospital, General Campus, 501 Smyth Road, Box 241, Ottawa, Ontario, Canada K1H 8LG
    BJOG 111:1294-6. 2004
    ..Multiple gestation pregnancies are associated with an increased risk of morbidity for the mother. This should be taken into consideration in antenatal care of these women...
  43. ncbi Excessive gestational weight gain predicts large for gestational age neonates independent of maternal body mass index
    Z M Ferraro
    Faculty of Health Sciences, School of Human Kinetics, University of Ottawa, Ontario, Canada
    J Matern Fetal Neonatal Med 25:538-42. 2012
    ..Lifestyle interventions that aim to optimize GWG by incorporating healthy eating and exercise strategies during pregnancy should be investigated to determine their effects on LGA neonates and down-stream child obesity...
  44. ncbi Relationship between intertwin delivery interval and metabolic acidosis in the second twin
    Fawaz Edris
    Obstetrics and Gynecology, Maternal Fetal Medicine, Ottawa Hospital, General Campus, Ottawa, Canada
    Am J Perinatol 23:481-5. 2006
    ..The incidence of metabolic acidosis increases with increasing ITDI and there is a statistically significant increased risk of neonatal acidosis after longer than 60 minutes compared with less than 15 minutes of ITDI...
  45. ncbi The risk of adverse pregnancy outcomes is increased in preeclamptic women who smoke compared with nonpreeclamptic women who do not smoke
    Elizabeth C Miller
    OMNI Research Group, Clinical Epidemiology Unit, Ottawa Health Research Institute, The Ottawa Hospital, Ottawa, ON, Canada
    Am J Obstet Gynecol 203:334.e1-8. 2010
    ..We sought to estimate the risk of adverse pregnancy outcomes among preeclamptic women who smoke and hypothesized that this risk would be increased, compared with nonpreeclamptic women who smoke or preeclamptic women who do not smoke...
  46. ncbi New-onset hypertension in late pregnancy and fetal growth: different associations between singletons and twins
    Xi Kuan Chen
    OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 26:259-72. 2007
    ..To compare the effects of new-onset hypertension (NOH) in late pregnancy on fetal growth in singletons and twins...
  47. ncbi Neonatal mortality and morbidity rates in term twins with advancing gestational age
    Jennifer E Soucie
    OMNI Research Group, Obstetrics and Gynecology and Clinical Epidemiology Program, Ottawa Hospital Research Institute, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 195:172-7. 2006
    ..The purpose of this study was to identify the gestational age with the lowest morbidity and mortality rates for twin pregnancies that reach term...
  48. ncbi Paternal age and birth defects: how strong is the association?
    Q Yang
    OMNI Research Group, Ottawa Hospital Research Institute, Ottawa, Canada
    Hum Reprod 22:696-701. 2007
    ..Although the association between maternal age and the risks of birth defects has been well studied, the evidence from population data linking paternal age with birth defects was limited and inconsistent...
  49. ncbi Early prediction of preterm birth for singleton, twin, and triplet pregnancies
    Hongzhuan Tan
    School of Public Health, Central South University, Changsha, Hunan, PR China
    Eur J Obstet Gynecol Reprod Biol 131:132-7. 2007
    ..To create prediction models of early preterm birth for singletons, twin, and triplet pregnancies...
  50. ncbi Impacts of operative delivery for the first twin on neonatal outcomes in the second twin
    Qiuying Yang
    OMNI Research Group, Ottawa Health Research Institute, Ottawa, Canada
    Am J Perinatol 23:381-6. 2006
    ....
  51. ncbi Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population
    Tubao Yang
    School of Public Health, Central South University, Changsha, Hunan, China
    Pharmacoepidemiol Drug Saf 17:270-7. 2008
    ..To estimate the frequency of exposure to prescription Food and Drug Administration (FDA) category C, D, and X drugs in pregnant women, and to analyze the maternal characteristics associated with such an exposure...
  52. ncbi Adequacy of prenatal care and neonatal mortality in infants born to mothers with and without antenatal high-risk conditions
    Xi Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    Aust N Z J Obstet Gynaecol 47:122-7. 2007
    ..Previous studies have found that inadequate prenatal care was associated with increased neonatal mortality in the general pregnant women...
  53. ncbi Determinants of caesarean delivery among women hospitalized for childbirth in a remote population in China
    Huizhong Lei
    Department of Obstetrics and Gynecology, Qingyuan People's Municipal Hospital, Qingyuan, China
    J Obstet Gynaecol Can 25:937-43. 2003
    ..CONCLUSION: Non-medical causes, including a woman's insurance status and her personal and social demands, accounted for a large proportion of elective Caesarean deliveries in this remote population in China...
  54. ncbi Parental race, birth weight, gestational age, and fetal growth among twin infants in the United States
    Hongzhuan Tan
    OMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, 501 Smyth Rd, Ottawa, Canada, K1H 8L6
    Early Hum Dev 80:153-60. 2004
    ..CONCLUSIONS: Both parents' races are important determinants of birth weight, gestational age, and fetal growth among twin pregnancies, with higher effect on gestational age and greater maternal influence than paternal influence...
  55. ncbi Infant sex, family support and postpartum depression in a Chinese cohort
    R H Xie
    OMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, 501 Smyth Rd, Box 241, Ottawa, Ontario, Canada
    J Epidemiol Community Health 65:722-6. 2011
    ..To assess the impact of prenatal and postnatal family support on the association between infant sex and postpartum depression (PPD)...
  56. ncbi Environmental lead level and pregnancy-induced hypertension
    Xi-Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada
    Environ Res 100:424-30. 2006
    ..The risk of PIH increased by 4% per 0.05 microg/m3 increase in seasonal average lead level at conception and birth, in both smokers and nonsmokers. These results suggest that higher environmental lead levels increase the risk of PIH...
  57. ncbi Relationship of prenatal diagnosis and pregnancy termination to overall infant mortality in Canada
    Shiliang Liu
    Health Surveillance and Epidemiology Division, HPB Bldg 7, Tunney s Pasture AL 0701D, Ottawa, Ontario, Canada K1A OL2
    JAMA 287:1561-7. 2002
    ..Prenatal diagnosis and termination of affected pregnancies can prevent infant deaths due to congenital anomalies, but an effect at the population level has not been shown...
  58. ncbi Recent oral contraceptive use and adverse birth outcomes
    Xi Kuan Chen
    McLaughlin Center for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ontario, Canada
    Eur J Obstet Gynecol Reprod Biol 144:40-3. 2009
    ..To examine the possible association between oral contraceptive use and adverse birth outcomes...
  59. ncbi New-onset hypertension in late pregnancy is associated with lower fetal and infant mortality in preterm twins
    Xi-Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 25:205-15. 2006
    ..CONCLUSION: NOH is associated with lower risk of fetal death and infant death in preterm twins...
  60. ncbi Determinants of intrapartum fetal death in a remote and indigent population in China
    Shi Wu Wen
    Department of Obstetrics and Gynecology and Clinical Epidemiology Program, University of Ottawa Faculty of Medicine, Ontario, Canada
    J Perinatol 24:77-81. 2004
    ..Other significant determinants were related to access to obstetric care (i.e., insurance status and residence). CONCLUSION: Lack of access to quality obstetric care is the major determinant of intrapartum fetal death in this population...
  61. ncbi Comparison of maternal risk factors between placental abruption and placenta previa
    Qiuying Yang
    OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, University of Ottawa, Ontario, Canada
    Am J Perinatol 26:279-86. 2009
    ..Placental abruption is more likely to be affected by conditions occurring during pregnancy, and placenta previa is more likely to be affected by conditions existing prior to pregnancy...
  62. ncbi Maternal cigarette smoking and the risk of pregnancy-induced hypertension and eclampsia
    Qiuying Yang
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ontario, Canada
    Int J Epidemiol 35:288-93. 2006
    ..No previous study has specifically examined the relationship between maternal smoking and eclampsia...
  63. ncbi Neonatal death and morbidity in vertex-nonvertex second twins according to mode of delivery and birth weight
    Qiuying Yang
    OMNI Research Group, Division of Maternal Fetal Medicine, Unveristy of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 192:840-7. 2005
    ..The purpose of this study was to assess the risk of neonatal death and morbidity in vertex-nonvertex second twins according to the mode of delivery and birth weight...
  64. ncbi Preeclampsia and gestational diabetes mellitus: pre-conception origins?
    S W Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Canada
    Med Hypotheses 79:120-5. 2012
    ....
  65. ncbi Adverse outcomes in pregnancies of asthmatic women: results from a Canadian population
    S W Wen
    Bureau of Reproductive and Child Health, Laboratory Center for Disease Control, Health Canada, Ottawa, Ontario
    Ann Epidemiol 11:7-12. 2001
    ..For this reason, pregnant women with asthma are a particularly high-risk group to which extra attention, including increased efforts at education, monitoring, and optimal asthma management, may be appropriate...
  66. ncbi Level of aggregation for optimal epidemiological analysis: the case of time to surgery and unnecessary removal of the normal appendix
    S W Wen
    Bureau of Reporductive and Child Health, Ottawa, Ontario, Canada
    J Epidemiol Community Health 55:198-203. 2001
    ..To illustrate the concept of "individualised fallacy", the result of improper interpretation and inference about aggregate level associations on the basis of associations at the individual level, in epidemiology...
  67. ncbi Survival analysis of liver transplant patients in Canada 1997-2002
    Z Hong
    Blood Safety Surveillance and Health Care Acquired Infection Division, Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario
    Transplant Proc 38:2951-6. 2006
    ..Liver transplantation is an important health care issue for Canadians. Very few studies have assessed survival and determinants of survival in liver transplant patients in Canada...
  68. ncbi Physical activity and the risk of lung cancer in Canada
    Yang Mao
    Surveillance and Risk Assessment Division, Centre for Chronic Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ontario, Canada
    Am J Epidemiol 158:564-75. 2003
    ..More studies are needed to confirm the differences between histologic subtypes and between genders and to address the underlying biologic mechanisms...
  69. ncbi Recent trends in caesarean delivery rates and indications for caesarean delivery in Canada
    Shiliang Liu
    Health Surveillance and Epidemiology Division, Centre for Healthy Human Development, Health Canada, Ottawa, ON
    J Obstet Gynaecol Can 26:735-42. 2004
    ..9% in 1994/95 to 1.3% in 2000/01. CONCLUSION: Most of the recent increase in Caesarean delivery rates in Canada was attributed to increases in primary Caesarean delivery for dystocia and elective repeat Caesarean deliveries...
  70. ncbi Maternal age, paternal age and new-onset hypertension in late pregnancy
    Xi-Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 25:217-27. 2006
    ..CONCLUSION: Increased risk for new-onset hypertension in late pregnancy is significantly associated with advancing maternal age, whereas there is no association between paternal age and new-onset hypertension in late pregnancy...
  71. ncbi The effect of parental race on fetal and infant mortality in twin gestations
    Hongzhuan Tan
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Canada
    J Natl Med Assoc 96:1337-43. 2004
    ..19-1.58) and lowest for W-W. Thus, twin infants born to black parents have higher risk of fetal and infant mortality compared with twin infants born to white parents and infants of mixed race parents generally have intermediate outcomes...
  72. ncbi The estimation of heritability for twin data based on concordances of sex and disease
    Hongzhuan Tan
    OMNI Research Group, Department of Obstetrics and Gynecology, The Ottawa Hospital, Ottawa, Ontario K1H 8L6, Canada
    Chronic Dis Can 26:9-12. 2005
    ..83% (95% CI 22.28% - 37.38%) estimated by our method and Holzinger's formula respectively. We conclude that our new method can be used in the estimation of heritability with large twin register data with no zygosity information available...
  73. ncbi Increased risks of neonatal and postneonatal mortality associated with teenage pregnancy had different explanations
    Xi Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada K1H 8L6
    J Clin Epidemiol 61:688-94. 2008
    ..To determine the potential pathway of the association between teenage pregnancy and neonatal and postneonatal mortality...
  74. ncbi Social disparity and the use of intrapartum epidural analgesia in a publicly funded health care system
    Ning Liu
    OMNI Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada
    Am J Obstet Gynecol 202:273.e1-8. 2010
    ..We sought to examine the difference in use of labor epidural analgesia among women from different neighborhood socioeconomic groups...
  75. ncbi Prenatal family support, postnatal family support and postpartum depression
    Ri Hua Xie
    Department of Obstetrics and Gynecology, University of Ottawa, Canada
    Aust N Z J Obstet Gynaecol 50:340-5. 2010
    ..In the family centred Chinese culture, family support is likely to be one of the most important components in social support...
  76. ncbi In vitro fertilization is associated with an increased risk for preeclampsia
    Xi Kuan Chen
    OMNI Research Group, Clinical Epidemiology Program, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 28:1-12. 2009
    ..To assess the association of intrauterine insemination, in vitro fertilization (IVF) and ovulation induction with the risk of preeclampsia...
  77. ncbi Trends in fetal and infant deaths caused by congenital anomalies
    Shiliang Liu
    Department of Epidemiology and Community Medicine, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Canada
    Semin Perinatol 26:268-76. 2002
    ..Further declines in overall infant mortality in industrialized countries can be expected as a result of an increasing uptake of prenatal diagnosis...
  78. ncbi Risk of fetal exposure to folic acid antagonists
    Shi Wu Wen
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, Ottawa ON
    J Obstet Gynaecol Can 26:475-80. 2004
    ..In this paper, strategies that may be used to reduce the risk of fetal exposure to folic acid antagonists are proposed...
  79. ncbi Teenage pregnancy and adverse birth outcomes: a large population based retrospective cohort study
    Xi Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    Int J Epidemiol 36:368-73. 2007
    ..The objective of this study was to determine whether teenage pregnancy is associated with increased adverse birth outcomes independent of known confounding factors...
  80. ncbi Paternal age and adverse birth outcomes: teenager or 40+, who is at risk?
    Xi Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, 501 Smyth Rd, Box 241, Ottawa, Ontario, Canada K1H 8L6
    Hum Reprod 23:1290-6. 2008
    ..The objective of this study was to determine whether paternal age is associated with the risk of adverse birth outcomes, independent of maternal confounders...
  81. ncbi Occurrence and determinants of trimethoprim/sulfamethoxazole use in pregnancy
    Tubao Yang
    Department of Epidemiology and Health Statistics, Central South University, Changsha, Hunan, China
    Acta Obstet Gynecol Scand 86:1310-6. 2007
    ..To estimate the rate of prescription trimethoprim/sulfamethoxazole use in pregnancy, and to analyse the association between maternal characteristics and use of trimethoprim/sulfamethoxazole in pregnancy...
  82. ncbi A case-control study of diet and the risk of ovarian cancer
    Sai Yi Pan
    Surveillance and Risk Assessment Division, Center for Chronic Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ontario, Canada
    Cancer Epidemiol Biomarkers Prev 13:1521-7. 2004
    ....
  83. ncbi An exploration of health effects of folic acid in pregnancy beyond reducing neural tube defects
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, Ottawa, ON
    J Obstet Gynaecol Can 27:13-9. 2005
    ....
  84. ncbi A survey of preconceptional folic acid use in a group of Canadian women
    Larissa E Tam
    Department of Obstetrics and Gynecology, Scarborough General Hospital, Toronto, Ontario, Canada
    J Obstet Gynaecol Can 27:232-6. 2005
    ..5; 95% CI, 1.4-1.6) and a lack of knowledge about when folic acid should be taken (adjusted RR 1.8; 95% CI, 1.6-1.8). CONCLUSION: Ethnic background is an independent predictor of periconceptional folic acid use...
  85. ncbi Association of obesity and cancer risk in Canada
    Sai Yi Pan
    Surveillance and Risk Assessment Division, Centre for Chronic Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ontario, Canada
    Am J Epidemiol 159:259-68. 2004
    ....
  86. ncbi Years of potential life lost in residents affected by floods in Hunan, China
    Xingli Li
    School of Public Health, Central South University, 88 Xiangya Road, Changsha, Hunan 410078, PR China
    Trans R Soc Trop Med Hyg 101:299-304. 2007
    ..26 and 26.60% in the river flood group and 10.56 and 7.80% in the drainage problems group. We conclude that floods increase the affected residents' SYPLL, and that the river flood had stronger effects than the drainage problems floods...
  87. ncbi Women's satisfaction with the current state of prenatal care for pregnancies complicated by fetal anomalies: a survey of five academic perinatal units in Ontario
    Tubao Yan
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa ON
    J Obstet Gynaecol Can 29:308-14. 2007
    ..To assess women's satisfaction with the current state of prenatal care for pregnancies complicated by congenital anomalies...
  88. ncbi Length of hospital stay, obstetric conditions at childbirth, and maternal readmission: a population-based cohort study
    Shiliang Liu
    Health Surveillance and Epidemiology Division, Centre for Healthy Human Development, Health Canada, and McLaughlin Center for Population Health Risk Assessment, University of Ottawa, ON, Canada
    Am J Obstet Gynecol 187:681-7. 2002
    ..We assessed the association between obstetric conditions, length of hospital stay for childbirth, and maternal readmission...
  89. ncbi A short DSM-IV screening scale to detect posttraumatic stress disorder after a natural disaster in a Chinese population
    Aizhong Liu
    School of Public Health, Central South University, Xiangya Road 110, Changsha, Hunan 410078, PR China
    Psychiatry Res 159:376-81. 2008
    ..3%, and negative predictive value of 98.7%. The short screening scale developed in this study is highly valid, reliable, and predictable. It is an efficient tool to screen PTSD in epidemiological and clinical studies...
  90. ncbi Why are babies getting bigger? Temporal trends in fetal growth and its determinants
    Michael S Kramer
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada
    J Pediatr 141:538-42. 2002
    ..To describe temporal trends in fetal "growth" and to examine the roles of sociodemographic, anthropometric, and other determinants...
  91. ncbi Determinants of breast-feeding and weaning in Alberta, Canada
    Qiuying Yang
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa ON
    J Obstet Gynaecol Can 26:975-81. 2004
    ..CONCLUSIONS: Smoking cessation during pregnancy, adequate treatment of early breast problems, and breast-feeding promotion campaigns targeting socioeconomically disadvantaged populations could serve to increase breast-feeding in Canada...
  92. ncbi Trends in fetal growth among singleton gestations in the United States and Canada, 1985 through 1998
    Cande V Ananth
    Department of Obstetrics, Gynecology and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, New Brunswick 08901, USA
    Semin Perinatol 26:260-7. 2002
    ..These findings suggest that US and Canadian babies are getting bigger. The role of preterm obstetrical induction and preterm cesarean delivery are likely to have influenced these trends...
  93. ncbi Risk of fetal exposure to tricyclic antidepressants
    Shi Wu Wen
    OMNI Research Group, Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Ottawa, Ottawa, ON
    J Obstet Gynaecol Can 26:887-92. 2004
    ..The findings from such studies will have direct implication on the use of TCAs in the clinical treatment of depression in pregnancy...
  94. ncbi The impact of the increasing number of multiple births on the rates of preterm birth and low birthweight: an international study
    Beatrice Blondel
    Epidemiological Research Unit on Perinatal Health and Women s health, National Institute for Health and Medical Research, Villejuif, France
    Am J Public Health 92:1323-30. 2002
    ..We studied the effects of twins and triplets on perinatal health indicators in the overall population in the 1980s and 1990s in Canada, England and Wales, France, and the United States...
  95. ncbi Fetal gender and postpartum depression in a cohort of Chinese women
    Ri Hua Xie
    Central South University, P R China
    Soc Sci Med 65:680-4. 2007
    ..We speculate that this is associated with the negative reactions of family members towards the birth of a female baby...
  96. ncbi Association of cigarette smoking with the risk of ovarian cancer
    Sai Yi Pan
    Surveillance and Risk Assessment Division, Centre for Chronic Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ontario, Canada
    Int J Cancer 111:124-30. 2004
    ..13, 2.65, 1.77 and 2.39 for <10, 11-20, 21-30 and >30 pack-years, respectively; p for trend = 0.004). Our data suggest that cigarette smoking is associated with an increased risk of ovarian cancer, especially for mucinous types...
  97. ncbi Physical inactivity, energy intake, obesity and the risk of rectal cancer in Canada
    Yang Mao
    Surveillance and Risk Assessment Division, Centre for Chronic Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ontario, Canada
    Int J Cancer 105:831-7. 2003
    ..Our study provides evidence that physical inactivity, high energy intake and obesity are associated with the risk of rectal cancer, and there is a probable synergic effect among the 3 risk factors...