J Grimshaw

Summary

Affiliation: Ottawa Health Research Institute
Country: Canada

Publications

  1. pmc Systematic reviews of the effectiveness of quality improvement strategies and programmes
    J Grimshaw
    Clinical Epidemiology Program, Ottawa Health Research Institute, ON, Canada
    Qual Saf Health Care 12:298-303. 2003
  2. pmc Variability in research ethics review of cluster randomized trials: a scenario-based survey in three countries
    Monica Taljaard
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, 1053 Carling Avenue, Civic Campus, C409, Ottawa, ON K1Y 4E9, Canada
    Trials 15:48. 2014
  3. pmc Implementing evidence-based recommended practices for the management of patients with mild traumatic brain injuries in Australian emergency care departments: study protocol for a cluster randomised controlled trial
    Marije Bosch
    Department of Surgery, Central Clinical School, Monash University, Melbourne, Australia
    Trials 15:281. 2014
  4. pmc Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol
    Manoj M Lalu
    Department of Medicine Division of Critical Care, University of Ottawa, Ottawa, ON, Canada
    Syst Rev 3:48. 2014
  5. pmc Effectiveness of brief interventions as part of the Screening, Brief Intervention and Referral to Treatment (SBIRT) model for reducing the nonmedical use of psychoactive substances: a systematic review
    Matthew M Young
    Canadian Centre on Substance Abuse CCSA, 75 Albert Street, Ottawa, Ontario K1P 5E7, Canada
    Syst Rev 3:50. 2014
  6. ncbi request reprint Seeing the forests and the trees--innovative approaches to exploring heterogeneity in systematic reviews of complex interventions to enhance health system decision-making: a protocol
    Noah Ivers
    Clinical Epidemiology Program, Ottawa Hospital Research Institute, Centre for Practice Changing Research, The Ottawa Hospital General Campus, 501 Smyth Road, Box 711, Ottawa, Ontario K1H 8L6, Canada
    Syst Rev 3:88. 2014
  7. ncbi request reprint Growing literature, stagnant science? Systematic review, meta-regression and cumulative analysis of audit and feedback interventions in health care
    Noah M Ivers
    Family Practice Health Centre and Institute for Health Systems Solutions and Virtual Care, Women s College Hospital, Toronto, Ontario, Canada
    J Gen Intern Med 29:1534-41. 2014
  8. ncbi request reprint Printed educational messages aimed at family practitioners fail to increase retinal screening among their patients with diabetes: a pragmatic cluster randomized controlled trial [ISRCTN72772651]
    Merrick Zwarenstein
    Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, 1465 Richmond Street, London, Ontario N6A 3K7, Canada
    Implement Sci 9:87. 2014
  9. pmc Application of theory to enhance audit and feedback interventions to increase the uptake of evidence-based transfusion practice: an intervention development protocol
    Natalie J Gould
    Centre for Health Services Research, City University London, London, UK
    Implement Sci 9:92. 2014
  10. pmc Organizational readiness for knowledge translation in chronic care: a review of theoretical components
    Randa Attieh
    Research Center of the Centre Hospitalier Universitaire de Québec, Hôpital St François d Assise, 45 rue Leclerc, Quebec, QC, Canada
    Implement Sci 8:138. 2013

Detail Information

Publications141 found, 100 shown here

  1. pmc Systematic reviews of the effectiveness of quality improvement strategies and programmes
    J Grimshaw
    Clinical Epidemiology Program, Ottawa Health Research Institute, ON, Canada
    Qual Saf Health Care 12:298-303. 2003
    ..This paper builds on our experiences within the Cochrane Effective Practice and Organisation of Care (EPOC) review group...
  2. pmc Variability in research ethics review of cluster randomized trials: a scenario-based survey in three countries
    Monica Taljaard
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, 1053 Carling Avenue, Civic Campus, C409, Ottawa, ON K1Y 4E9, Canada
    Trials 15:48. 2014
    ....
  3. pmc Implementing evidence-based recommended practices for the management of patients with mild traumatic brain injuries in Australian emergency care departments: study protocol for a cluster randomised controlled trial
    Marije Bosch
    Department of Surgery, Central Clinical School, Monash University, Melbourne, Australia
    Trials 15:281. 2014
    ..The primary objective is to establish whether the intervention is effective in increasing the percentage of patients for which appropriate post-traumatic amnesia screening is performed...
  4. pmc Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol
    Manoj M Lalu
    Department of Medicine Division of Critical Care, University of Ottawa, Ottawa, ON, Canada
    Syst Rev 3:48. 2014
    ..Prior to a human clinical trial, our aim is to conduct a systematic review to compare the efficacy and safety of MSC therapy versus controls in preclinical models of acute lung injury that mimic some aspects of the human ARDS...
  5. pmc Effectiveness of brief interventions as part of the Screening, Brief Intervention and Referral to Treatment (SBIRT) model for reducing the nonmedical use of psychoactive substances: a systematic review
    Matthew M Young
    Canadian Centre on Substance Abuse CCSA, 75 Albert Street, Ottawa, Ontario K1P 5E7, Canada
    Syst Rev 3:50. 2014
    ....
  6. ncbi request reprint Seeing the forests and the trees--innovative approaches to exploring heterogeneity in systematic reviews of complex interventions to enhance health system decision-making: a protocol
    Noah Ivers
    Clinical Epidemiology Program, Ottawa Hospital Research Institute, Centre for Practice Changing Research, The Ottawa Hospital General Campus, 501 Smyth Road, Box 711, Ottawa, Ontario K1H 8L6, Canada
    Syst Rev 3:88. 2014
    ..This study will explore the role of innovative meta-analysis approaches and the added value of enriched and updated data for increasing the utility of systematic reviews of complex interventions...
  7. ncbi request reprint Growing literature, stagnant science? Systematic review, meta-regression and cumulative analysis of audit and feedback interventions in health care
    Noah M Ivers
    Family Practice Health Centre and Institute for Health Systems Solutions and Virtual Care, Women s College Hospital, Toronto, Ontario, Canada
    J Gen Intern Med 29:1534-41. 2014
    ....
  8. ncbi request reprint Printed educational messages aimed at family practitioners fail to increase retinal screening among their patients with diabetes: a pragmatic cluster randomized controlled trial [ISRCTN72772651]
    Merrick Zwarenstein
    Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, 1465 Richmond Street, London, Ontario N6A 3K7, Canada
    Implement Sci 9:87. 2014
    ..We aimed to evaluate the ability of printed educational messages aimed at family doctors to increase retinal screening of primary care patients with diabetes...
  9. pmc Application of theory to enhance audit and feedback interventions to increase the uptake of evidence-based transfusion practice: an intervention development protocol
    Natalie J Gould
    Centre for Health Services Research, City University London, London, UK
    Implement Sci 9:92. 2014
    ..This study is part of a larger programme of work to promote the uptake of evidence-based transfusion practice...
  10. pmc Organizational readiness for knowledge translation in chronic care: a review of theoretical components
    Randa Attieh
    Research Center of the Centre Hospitalier Universitaire de Québec, Hôpital St François d Assise, 45 rue Leclerc, Quebec, QC, Canada
    Implement Sci 8:138. 2013
    ..Yet, organizations aiming to improve chronic care (CC) require an adequate level of organizational readiness (OR) for KT...
  11. ncbi request reprint Are multifaceted interventions more effective than single-component interventions in changing health-care professionals' behaviours? An overview of systematic reviews
    Janet E Squires
    School of Nursing, University of Ottawa, Ottawa, Canada
    Implement Sci 9:152. 2014
    ....
  12. pmc Improving Diabetes care through Examining, Advising, and prescribing (IDEA): protocol for a theory-based cluster randomised controlled trial of a multiple behaviour change intervention aimed at primary healthcare professionals
    Justin Presseau
    Institute of Health and Society, Newcastle University, Baddiley Clark building, Richardson Road, Newcastle upon Tyne NE2 4AX, England
    Implement Sci 9:61. 2014
    ..The present study builds on findings from a UK-wide study of theory-based behavioural and organisational factors associated with prescribing, advising, and examining consistent with high-quality diabetes care...
  13. pmc Towards a common terminology: a simplified framework of interventions to promote and integrate evidence into health practices, systems, and policies
    Heather Colquhoun
    Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa Hospital General Campus, 501 Smyth Road, C, P, 711, K1H 8 L6 Ottawa, ON, Canada
    Implement Sci 9:51. 2014
    ..In 2012, we convened an international working group to explore the idea of developing a common terminology and an overarching framework for knowledge translation interventions...
  14. pmc No more 'business as usual' with audit and feedback interventions: towards an agenda for a reinvigorated intervention
    Noah M Ivers
    Department of Family and Community Medicine, Institute for Health Systems Solutions and Virtual Care, Women s College Hospital, University of Toronto, 77 Grenville Street, Toronto, ON M5S 1B3, Canada
    Implement Sci 9:14. 2014
    ..Audit and feedback interventions in healthcare have been found to be effective, but there has been little progress with respect to understanding their mechanisms of action or identifying their key 'active ingredients.'..
  15. pmc Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol
    Janet E Squires
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, 501 Smyth Road, Room 1282, Box 711, Ottawa, ON K1H 8 L6, Canada
    Implement Sci 9:80. 2014
    ....
  16. pmc Feedback GAP: pragmatic, cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care
    Noah M Ivers
    Department of Family and Community Medicine, Women s College Hospital, 76 Grenville Street, Toronto, ON M5S 1B2, Canada
    Implement Sci 8:142. 2013
    ..This trial tested the effects of a theory-informed worksheet to facilitate goal setting and action planning, appended to feedback reports on chronic disease management, compared to feedback reports provided without these worksheets...
  17. pmc Evidence-based care of older people with suspected cognitive impairment in general practice: protocol for the IRIS cluster randomised trial
    Joanne E McKenzie
    School of Public Health and Preventive Medicine, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, Australia
    Implement Sci 8:91. 2013
    ..This protocol describes methods of a randomised trial that tests a theory-informed implementation intervention that, if effective, may provide benefits for patients with dementia and their carers...
  18. pmc Looking inside the black box: results of a theory-based process evaluation exploring the results of a randomized controlled trial of printed educational messages to increase primary care physicians' diabetic retinopathy referrals [Trial registration numbe
    Jeremy M Grimshaw
    Ottawa Hospital Research Institute, The Ottawa Hospital General Campus, 501 Smyth Road, Box 711, Ottawa, Ontario K1H 8 L6, Canada
    Implement Sci 9:86. 2014
    ..We hypothesized that the PEMs would increase physicians' intention to refer patients for retinal screening by strengthening their attitude and subjective norm, but not their perceived behavioral control...
  19. pmc Researchers' perceptions of ethical challenges in cluster randomized trials: a qualitative analysis
    Andrew D McRae
    Division of Emergency Medicine, University of Calgary, Foothills Medical Centre, Rm C231, 1403 29 Street NW, Calgary, Alberta T2N 2T9, Canada
    Trials 14:1. 2013
    ..This study describes the views and experiences of CRT researchers with respect to: (1) ethical challenges in CRTs; (2) the ethics review process for CRTs; and (3) the need for comprehensive ethics guidelines for CRTs...
  20. pmc Allocation techniques for balance at baseline in cluster randomized trials: a methodological review
    Noah M Ivers
    Family Practice Health Centre, Women s College Hospital, 76 Grenville Street, Toronto, ON, M5S1B2, Canada
    Trials 13:120. 2012
    ....
  21. pmc What is the role and authority of gatekeepers in cluster randomized trials in health research?
    Antonio Gallo
    Rotman Institute of Philosophy, University of Western Ontario, London, ON N6A 5B8, Canada
    Trials 13:116. 2012
    ..In these settings, permission to access the organization relies on resource implications and adherence to institutional policies...
  22. pmc Overview of systematic reviews of the effectiveness of reminders in improving healthcare professional behavior
    Amy Cheung
    Department of Psychiatry, University of Toronto, 33 Russell St, 3rd Floor Tower, Toronto, ON, Canada
    Syst Rev 1:36. 2012
    ..The purpose of this project was to conduct an overview of existing systematic reviews to evaluate the effectiveness of reminders in changing professional behavior in clinical settings...
  23. pmc Effectiveness of brief interventions as part of the screening, brief intervention and referral to treatment (SBIRT) model for reducing the non-medical use of psychoactive substances: a systematic review protocol
    Matthew M Young
    Canadian Centre on Substance Abuse CCSA, 75 Albert Street, Ottawa, ON, K1P 5E7, Canada
    Syst Rev 1:22. 2012
    ....
  24. pmc What supports do health system organizations have in place to facilitate evidence-informed decision-making? A qualitative study
    Moriah E Ellen
    Centre for Health Economics and Policy Analysis, McMaster University, 1280 Main Street West, CRL 209, Hamilton, ON, Canada L8S 4K1
    Implement Sci 8:84. 2013
    ..Healthcare organizations can implement tools and infrastructures to support the use of research evidence to inform decision-making...
  25. pmc A systematic review of the use of theory in randomized controlled trials of audit and feedback
    Heather L Colquhoun
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital, General Campus, 501 Smyth Road, Centre for Practice Changing Research, Box 201B, Ottawa, Ontario K1H 8L6, Canada
    Implement Sci 8:66. 2013
    ..Examining the extent of theory use in studies of audit and feedback will yield better understanding of the causal pathways of audit and feedback effectiveness and inform efforts to optimize this important intervention...
  26. pmc Development of two shortened systematic review formats for clinicians
    Laure Perrier
    Li Ka Shing Knowledge Institute, St Michael s Hospital, 30 Bond Street, Toronto, ON M5B 1W8, Canada
    Implement Sci 8:68. 2013
    ..The purpose of this paper is to describe the development process of two shortened formats for a systematic review intended for use by primary care physicians as an information tool for clinical decision-making...
  27. pmc Best strategies to implement clinical pathways in an emergency department setting: study protocol for a cluster randomized controlled trial
    Mona Jabbour
    Division of Emergency Medicine, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Implement Sci 8:55. 2013
    ..This study will seek to develop and comprehensively evaluate best strategies for effective local implementation of externally developed expert clinical pathways...
  28. pmc Assessing availability of scientific journals, databases, and health library services in Canadian health ministries: a cross-sectional study
    Grégory Léon
    Centre Hospitalier Universitaire de Québec Research Centre, Hôpital St François d Assise, Quebec City, QC, Canada
    Implement Sci 8:34. 2013
    ....
  29. pmc Understanding the Canadian adult CT head rule trial: use of the theoretical domains framework for process evaluation
    Janet A Curran
    Clinical Epidemiology Program, Ottawa Hospital Research Institute, Civic Campus, Ottawa, ON, Canada
    Implement Sci 8:25. 2013
    ..In this proof of concept study, we explored whether the TDF could be used to guide a retrospective process evaluation to better understand emergency physicians' responses to the interventions employed in the Canadian CT Head Rule trial...
  30. pmc Improving physician hand hygiene compliance using behavioural theories: a study protocol
    Janet E Squires
    Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada
    Implement Sci 8:16. 2013
    ..We aim to first identify the barriers and enablers to physician hand hygiene compliance, and then to develop and pilot a theory-based knowledge translation intervention to increase physicians' compliance with best hand hygiene practice...
  31. pmc Delayed educational reminders for long-term medication adherence in ST-elevation myocardial infarction (DERLA-STEMI): protocol for a pragmatic, cluster-randomized controlled trial
    Noah M Ivers
    Family Practice Health Centre, Women s College Research Institute, Women s College Hospital, 76 Grenville Ave Toronto, Toronto, Ontario, Canada
    Implement Sci 7:54. 2012
    ..Discontinuation of cardiac medications in such patients is associated with increased mortality...
  32. pmc A cross-country comparison of intensive care physicians' beliefs about their transfusion behaviour: a qualitative study using the Theoretical Domains Framework
    Rafat Islam
    Centre for Practice Changing Research, Ottawa Hospital Research Institute, General Campus, Ottawa, Canada
    Implement Sci 7:93. 2012
    ....
  33. pmc Developing clinical practice guidelines: target audiences, identifying topics for guidelines, guideline group composition and functioning and conflicts of interest
    Martin P Eccles
    Institute of Health and Society, Newcastle University, Baddiley Clark building, Richardson Road, Newcastle upon Tyne NE2 4AX, UK
    Implement Sci 7:60. 2012
    ....
  34. pmc Anesthesiologists' and surgeons' perceptions about routine pre-operative testing in low-risk patients: application of the Theoretical Domains Framework (TDF) to identify factors that influence physicians' decisions to order pre-operative tests
    Andrea M Patey
    Centre for Practice Changing Research, Ottawa Hospital Research Institute General Campus, Smyth Road, Ottawa, ON, Canada
    Implement Sci 7:52. 2012
    ..In this study, the TDF is used to explore anaesthesiologists' and surgeons' perceptions of ordering routine tests for healthy patients undergoing low-risk surgery...
  35. pmc Developing clinical practice guidelines: reviewing, reporting, and publishing guidelines; updating guidelines; and the emerging issues of enhancing guideline implementability and accounting for comorbid conditions in guideline development
    Paul Shekelle
    RAND Corporation, Santa Monica, CA 90407, USA
    Implement Sci 7:62. 2012
    ....
  36. pmc Explaining clinical behaviors using multiple theoretical models
    Martin P Eccles
    College of Life Sciences and Medicine, University of Aberdeen, Health Sciences Building 2nd floor, Foresterhill, Aberdeen, United Kingdom
    Implement Sci 7:99. 2012
    ..We reflect on the strengths and weaknesses of the methods, the performance of the theories, and consider where these methods sit alongside the range of methods for studying healthcare professional behavior change...
  37. pmc Identifying factors likely to influence compliance with diagnostic imaging guideline recommendations for spine disorders among chiropractors in North America: a focus group study using the Theoretical Domains Framework
    André E Bussières
    Population Health Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada
    Implement Sci 7:82. 2012
    ..A secondary objective was to compare chiropractors in the United States and Canada on their beliefs regarding the use of spine x-rays...
  38. pmc Developing theory-informed behaviour change interventions to implement evidence into practice: a systematic approach using the Theoretical Domains Framework
    Simon D French
    School of Public Health and Preventive Medicine, Monash University, Level 6, The Alfred Centre, 99 Commercial Road, Melbourne, Victoria 3004, Australia
    Implement Sci 7:38. 2012
    ..This article is one in a Series of articles documenting the development and use of the Theoretical Domains Framework (TDF) to advance the science of implementation research...
  39. pmc Developing clinical practice guidelines: types of evidence and outcomes; values and economics, synthesis, grading, and presentation and deriving recommendations
    Steven Woolf
    Department of Family Medicine and Center on Human Needs, Virginia Commonwealth University, Richmond, VA, USA
    Implement Sci 7:61. 2012
    ....
  40. pmc EXACKTE(2): exploiting the clinical consultation as a knowledge transfer and exchange environment: a study protocol
    France Legare
    Research Center of the Centre Hospitalier Universitaire de Québec, Quebec, Canada
    Implement Sci 4:14. 2009
    ....
  41. pmc Engaging primary care practitioners in quality improvement: making explicit the program theory of an interprofessional education intervention
    Brigitte Vachon
    School of Rehabilitation, Faculty of Medicine, Universite de Montreal, 7077 Park Avenue, Montreal, Quebec H3N 1X7, Canada
    BMC Health Serv Res 13:106. 2013
    ..The objectives of this study were to explain explicitly the theory underlying this intervention, to describe its components in detail and to assess the intervention's feasibility and acceptability...
  42. pmc Do incentives, reminders or reduced burden improve healthcare professional response rates in postal questionnaires? two randomised controlled trials
    Liz Glidewell
    Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
    BMC Health Serv Res 12:250. 2012
    ....
  43. pmc Improving quality of care for persons with diabetes: an overview of systematic reviews - what does the evidence tell us?
    Julia Worswick
    Cochrane Effective Practice and Organisation of Care Group, Centre for Practice Changing Research, Ottawa Hospital Research Institute, The Ottawa Hospital General Campus, 501 Smyth Road, Box 711, Ottawa, Ontario K1H 8M5, Canada
    Syst Rev 2:26. 2013
    ..These reviews are of varying quality and dispersed across many sources. In this paper, we present an overview of systematic reviews evaluating the impact of interventions to improve the quality of diabetes care...
  44. pmc Knowledge translation of research findings
    Jeremy M Grimshaw
    Department of Medicine, Clinical Epidemiology Program, Ottawa Hospital Research Institute, University of Ottawa, 501 Smyth Road, Box 711, Ottawa, ON, K1H 8L6, Canada
    Implement Sci 7:50. 2012
    ..what should be transferred; to whom should research knowledge be transferred; by whom should research knowledge be transferred; how should research knowledge be transferred; and, with what effect should research knowledge be transferred?..
  45. pmc Evidence summaries: the evolution of a rapid review approach
    Sara Khangura
    Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Road, Box 208, Ottawa, Ontario, K1H 8L6, Canada
    Syst Rev 1:10. 2012
    ..This paper outlines our experience with rapidly producing, publishing and disseminating evidence summaries in the context of our Knowledge to Action (KTA) research program...
  46. pmc Core competencies in the science and practice of knowledge translation: description of a Canadian strategic training initiative
    Sharon E Straus
    Li Ka Shing Knowledge Institute, St Michael s Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada
    Implement Sci 6:127. 2011
    ..This challenge has resulted in the development of implementation science or knowledge translation (KT) and the resulting need to build capacity in both the science and practice of KT...
  47. pmc Does the world need a scientific society for research on how to improve healthcare?
    Michel Wensing
    Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
    Implement Sci 7:10. 2012
    ..We invite readers to express their views in the online questionnaire accessed by following the URL link provided at the end of the editorial...
  48. pmc A cluster randomised trial of educational messages to improve the primary care of diabetes
    Robbie Foy
    Leeds Institute of Health Sciences, Charles Thackrah Building, University of Leeds, 101 Clarendon Road, Leeds LS2 9LJ, UK
    Implement Sci 6:129. 2011
    ..Regular laboratory test monitoring of patient parameters offers a route for improving the quality of chronic disease care. We evaluated the effects of brief educational messages attached to laboratory test reports on diabetes care...
  49. pmc Understanding implementation processes of clinical pathways and clinical practice guidelines in pediatric contexts: a study protocol
    Shannon D Scott
    Faculty of Nursing, University of Alberta, Edmonton, AB, Canada
    Implement Sci 6:133. 2011
    ..This study focuses on improving health outcomes for common paediatric acute health concerns by evaluating strategies that improve KT and reduce clinical practice variation...
  50. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 5: Using research evidence to frame options to address a problem
    John N Lavis
    Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada L8N 3Z5
    Health Res Policy Syst 7:S5. 2009
    ..What adaptations might be made to any given option and could they alter its benefits, harms and costs? 6. Which stakeholder views and experiences might influence an option's acceptability and its benefits, harms, and costs?..
  51. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 7: Finding systematic reviews
    John N Lavis
    Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
    Health Res Policy Syst 7:S7. 2009
    ..These are: 1. Is a systematic review really what is needed? 2. What databases and search strategies can be used to find relevant systematic reviews? 3. What alternatives are available when no relevant review can be found?..
  52. pmc Five years of Trials
    Douglas G Altman
    Centre for Statistics in Medicine, Wolfson College Annexe, Linton Road, Oxford OX2 6UD, UK
    Trials 12:248. 2011
    ..These include the publication of raw data, extended versions of previously published trial-related articles, descriptions of 'lessons learned', negative results, and educational articles regarding ethics and reporting bias...
  53. pmc When is informed consent required in cluster randomized trials in health research?
    Andrew D McRae
    Department of Epidemiology and Biostatistics, University of Western Ontario, London, ON N6A5C1, Canada
    Trials 12:202. 2011
    ..Fifth, while health professionals may have a moral obligation to participate as subjects in research, this does not diminish the necessity of informed consent to study participation...
  54. pmc Who is the research subject in cluster randomized trials in health research?
    Andrew D McRae
    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada
    Trials 12:183. 2011
    ..Individuals who are indirectly affected by CRT study interventions, including patients of healthcare providers participating in knowledge translation CRTs, are not human research subjects unless at least one of these conditions is met...
  55. pmc Does clinical equipoise apply to cluster randomized trials in health research?
    Ariella Binik
    Rotman Institute of Philosophy, Department of Philosophy, University of Western Ontario, London, ON, N6A 5B8, Canada
    Trials 12:118. 2011
    ..Finally, clinical equipoise provides research ethics committees with formal and procedural guidelines that form an important part of the assessment of the benefits and harms of CRTs in health research...
  56. pmc Ethical issues posed by cluster randomized trials in health research
    Charles Weijer
    Rotman Institute of Philosophy, Department of Philosophy, University of Western Ontario, London, ON, N6A 5B8, Canada
    Trials 12:100. 2011
    ..Our hope is that these papers will serve as the basis for the creation of international ethical guidelines for the design and conduct of cluster randomized trials...
  57. pmc Comparative effectiveness research: challenges for medical journals
    Harold C Sox
    Dartmouth Institute, Dartmouth Medical School, Hanover, New Hampshire, USA
    Trials 11:45. 2010
    ....
  58. pmc Compliance of clinical trial registries with the World Health Organization minimum data set: a survey
    Lorenzo P Moja
    Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Trials 10:56. 2009
    ..The objective is to evaluate registries' and individual trial records' compliance with the 2006 version of the WHO minimum data set...
  59. pmc Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research study
    Monica Taljaard
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa Hospital, 1053 Carling Avenue, Civic Campus, C409, Ottawa, ON K1Y4E9, Canada
    Trials 10:61. 2009
    ....
  60. pmc An exploration of how guideline developer capacity and guideline implementability influence implementation and adoption: study protocol
    Anna R Gagliardi
    Toronto General Research Institute, 200 Elizabeth Street, 13EN 235, Toronto, Ontario, M5G2C4, Canada
    Implement Sci 4:36. 2009
    ..If successful, then long-term objective outcomes reflecting the adoption of processes and associated patient care outcomes could be evaluated...
  61. pmc Understanding the relationship between the perceived characteristics of clinical practice guidelines and their uptake: protocol for a realist review
    Monika Kastner
    Li Ka Shing Knowledge Institute of St, Michael s Hospital, Toronto, Ontario, Canada
    Implement Sci 6:69. 2011
    ....
  62. pmc Opinion leaders and changes over time: a survey
    Gaby Doumit
    Institute of Dermatology and Plastic Surgery, Cleveland Clinic, Cleveland, OH, USA
    Implement Sci 6:117. 2011
    ..e., influencing multiple practice areas) or monomorphic (i.e., influencing one practice area), and reach of opinion leaders in their local network...
  63. pmc Tailored Implementation For Chronic Diseases (TICD): a project protocol
    Michel Wensing
    Scientific Institute for Quality of Healthcare, Nijmegen, Radboud University Nijmegen Medical Centre, Geert Grooteplein, Nijmegen, The Netherlands
    Implement Sci 6:103. 2011
    ....
  64. pmc Feedback GAP: study protocol for a cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care
    Noah M Ivers
    Women s College Hospital Family Health Team, 76 Grenville Street, Toronto ON, M5 S 1B2, Canada
    Implement Sci 5:98. 2010
    ..abstract:..
  65. pmc Measuring organizational readiness for knowledge translation in chronic care
    Marie Pierre Gagnon
    Research Center of the Centre Hospitalier Universitaire de Québec, Quebec, Canada
    Implement Sci 6:72. 2011
    ..We will specifically test the instrument in chronic care that is of an increasing importance for the health system...
  66. pmc Study protocol: the DESPATCH study: delivering stroke prevention for patients with atrial fibrillation - a cluster randomised controlled trial in primary healthcare
    Melina Gattellari
    School of Public Health and Community Medicine, The University of New South Wales, Sydney, Australia
    Implement Sci 6:48. 2011
    ..Despite this evidence, anticoagulation is substantially underused, resulting in avoidable fatal and disabling strokes...
  67. pmc Effects of an evidence service on community-based AIDS service organizations' use of research evidence: a protocol for a randomized controlled trial
    Michael G Wilson
    McMaster Health Forum, Hamilton, Canada
    Implement Sci 6:52. 2011
    ..Our objective is to evaluate whether this 'full serve' evidence service increases the use of research evidence by CBOs as compared to a 'self-serve' evidence service...
  68. pmc Determining research knowledge infrastructure for healthcare systems: a qualitative study
    Moriah E Ellen
    Centre for Health Economics and Policy Analysis, McMaster University, Hamilton, Ontario, Canada
    Implement Sci 6:60. 2011
    ....
  69. pmc Instrument development, data collection, and characteristics of practices, staff, and measures in the Improving Quality of Care in Diabetes (iQuaD) Study
    Martin P Eccles
    Institute of Health and Society, Newcastle University, Baddiley Clark building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK
    Implement Sci 6:61. 2011
    ....
  70. pmc Effects of an evidence service on health-system policy makers' use of research evidence: a protocol for a randomised controlled trial
    John N Lavis
    McMaster Health Forum, Hamilton, Canada
    Implement Sci 6:51. 2011
    ....
  71. pmc How can we improve guideline use? A conceptual framework of implementability
    Anna R Gagliardi
    Departments of Surgery and Department of Health Policy, Management and Evaluation and Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Implement Sci 6:26. 2011
    ..The purpose of this study was to identify and define features that facilitate guideline use, and examine whether and how they are included in current guidelines...
  72. pmc Developing a theory-based instrument to assess the impact of continuing professional development activities on clinical practice: a study protocol
    France Legare
    Research Center of the Centre Hospitalier Universitaire de Québec, Hospital St François D Assise, Quebec, Canada
    Implement Sci 6:17. 2011
    ..Using an integrated model for the study of healthcare professionals' behaviour, our objective is to develop a theory-based, valid, reliable global instrument to assess the impact of accredited CPD activities on clinical practice...
  73. pmc Use of communities of practice in business and health care sectors: A systematic review
    Linda C Li
    Department of Physical Therapy, University of British Columbia Arthritis Research Centre of Canada, Vancouver, Canada
    Implement Sci 4:27. 2009
    ....
  74. pmc Specifying and reporting complex behaviour change interventions: the need for a scientific method
    Susan Michie
    Centre for Outcomes Research and Effectiveness, Department of Clinical, Educational and Health Psychology, University College London, 1 19 Torrington Place, London, WC1E 7HB, UK
    Implement Sci 4:40. 2009
    ..Implementation Science is introducing a policy of initially encouraging and subsequently requiring the scientific reporting of complex behaviour change interventions...
  75. pmc Improving the delivery of care for patients with diabetes through understanding optimised team work and organisation in primary care
    Martin P Eccles
    Institute of Health and Society, University of Newcastle upon Tyne, 21 Claremont Place, Newcastle upon Tyne, NE2 4AA, UK
    Implement Sci 4:22. 2009
    ..STUDY REGISTRATION: UKCRN ref:DRN120 (ICPD)...
  76. pmc Improving the care for people with acute low-back pain by allied health professionals (the ALIGN trial): A cluster randomised trial protocol
    Joanne E McKenzie
    School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
    Implement Sci 5:86. 2010
    ..Outcome assessors will be blinded to group allocation. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry ACTRN12609001022257 (date registered 25th November 2009)...
  77. pmc Fever, hyperglycaemia and swallowing dysfunction management in acute stroke: A cluster randomised controlled trial of knowledge transfer
    Sandy Middleton
    St Vincents and Mater Health Sydney, Victoria St, Darlinghurst, 2010, NSW, Australia
    Implement Sci 4:16. 2009
    ..TRIAL REGISTRATION: Australia New Zealand Clinical Trial Registry (ANZCTR) No: ACTRN12608000563369...
  78. pmc Evolution of Wenger's concept of community of practice
    Linda C Li
    Department of Physical Therapy, University of British Columbia, Arthritis Research Centre of Canada, Vancouver, Canada
    Implement Sci 4:11. 2009
    ..Interventions that facilitate relationship building among members and that promote knowledge exchange may be useful for optimizing the function of these groups...
  79. pmc Using the theory of planned behaviour as a process evaluation tool in randomised trials of knowledge translation strategies: A case study from UK primary care
    Craig R Ramsay
    Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK
    Implement Sci 5:71. 2010
    ....
  80. pmc Applying psychological theories to evidence-based clinical practice: identifying factors predictive of placing preventive fissure sealants
    Debbie Bonetti
    Dental Health Services Research Unit, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    Implement Sci 5:25. 2010
    ..However a number of conceptual and methodological challenges remain...
  81. pmc The translation research in a dental setting (TRiaDS) programme protocol
    Jan E Clarkson
    Dental Health Services and Research Unit, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee, DD2 4BF, UK
    Implement Sci 5:57. 2010
    ....
  82. pmc Barriers and facilitators to the dissemination of DECISION+, a continuing medical education program for optimizing decisions about antibiotics for acute respiratory infections in primary care: a study protocol
    Anne Sophie Allaire
    Research Center of Centre Hospitalier Universitaire de Québec, Hospital St François D Assise, Knowledge Transfer an Health Technology Assessment Research Group, 10 rue de l Espinay, Quebec, QC, G1L 3L5, Canada
    Implement Sci 6:3. 2011
    ..The objective of this study is to identify the barriers and facilitators to physicians' participation in DECISION+ with the goal of disseminating DECISION+ on a larger scale...
  83. pmc Intracluster correlation coefficients in cluster randomized trials: empirical insights into how should they be reported
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    BMC Med Res Methodol 4:9. 2004
    ..Similarly, the need for appropriate standards of reporting of cluster trials is more widely acknowledged...
  84. pmc Electronic search strategies to identify reports of cluster randomized trials in MEDLINE: low precision will improve with adherence to reporting standards
    Monica Taljaard
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa, Canada
    BMC Med Res Methodol 10:15. 2010
    ....
  85. pmc Cluster randomized trial of an active, multifaceted information dissemination intervention based on The WHO Reproductive health library to change obstetric practices: methods and design issues [ISRCTN14055385]
    A Metin Gulmezoglu
    UNDP UNFPA WHO World Bank Special Programme on Research, Development and Research Training in Human Reproduction HRP, Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland
    BMC Med Res Methodol 4:2. 2004
    ..We are conducting a trial to evaluate the improvement in obstetric practices using an active dissemination strategy to promote uptake of recommendations in The WHO Reproductive Health Library (RHL)...
  86. pmc Does updating improve the methodological and reporting quality of systematic reviews?
    Beverley Shea
    Community Information and Epidemiological Technologies CIET, Ottawa, Ontario, Canada
    BMC Med Res Methodol 6:27. 2006
    ..The purpose of our research was to compare the methodological and reporting quality of original versus updated Cochrane SRs to determine whether updating had improved these two quality dimensions...
  87. pmc Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews
    Beverley J Shea
    EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
    BMC Med Res Methodol 7:10. 2007
    ..Our objective was to develop an instrument to assess the methodological quality of systematic reviews, building upon previous tools, empirical evidence and expert consensus...
  88. pmc What do we know about how to do audit and feedback? Pitfalls in applying evidence from a systematic review
    R Foy
    Centre for Health Services Research, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
    BMC Health Serv Res 5:50. 2005
    ..We set out to assess whether current guidance and systematic review evidence can sufficiently inform practical decisions about how to use audit and feedback to improve quality of care...
  89. pmc The relationship between organisational characteristics and the effects of clinical guidelines on medical performance in hospitals, a meta-analysis
    Rob Dijkstra
    Centre for Quality of Care Research 117, Radboud University, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    BMC Health Serv Res 6:53. 2006
  90. pmc PRIME--PRocess modelling in ImpleMEntation research: selecting a theoretical basis for interventions to change clinical practice
    Anne E Walker
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    BMC Health Serv Res 3:22. 2003
    ....
  91. pmc The development of a theory-based intervention to promote appropriate disclosure of a diagnosis of dementia
    Robbie Foy
    Institute of Health and Society, Newcastle University, 21 Claremont Place, Newcastle upon Tyne NE2 4AA, UK
    BMC Health Serv Res 7:207. 2007
    ..We set out to develop an intervention to promote appropriate disclosure of a diagnosis of dementia based on theoretical and empirical work...
  92. pmc Developing the content of two behavioural interventions: using theory-based interventions to promote GP management of upper respiratory tract infection without prescribing antibiotics #1
    Susan Hrisos
    Institute of Health and Society, Newcastle University, UK
    BMC Health Serv Res 8:11. 2008
    ..The purpose of this study was to design two theoretically-based interventions to promote the management of upper respiratory tract infection (URTI) without prescribing antibiotics...
  93. pmc An intervention modelling experiment to change GPs' intentions to implement evidence-based practice: using theory-based interventions to promote GP management of upper respiratory tract infection without prescribing antibiotics #2
    Susan Hrisos
    Institute of Health and Society, Newcastle University, UK
    BMC Health Serv Res 8:10. 2008
    ....
  94. pmc Training family physicians and residents in family medicine in shared decision making to improve clinical decisions regarding the use of antibiotics for acute respiratory infections: protocol for a clustered randomized controlled trial
    France Legare
    Research Center of Centre Hospitalier Universitaire de Québec, Hospital St François D Assise, Knowledge Transfer and Health Technology Assessment Research Group, 10 Espinay, Quebec, QC, G1L 3L5, Canada
    BMC Fam Pract 12:3. 2011
    ....
  95. pmc A survey of factors associated with the successful recognition of agonal breathing and cardiac arrest by 9-1-1 call takers: design and methodology
    Christian Vaillancourt
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital Civic Campus Floor 6, Box 685, 1053 Carling Avenue, Ottawa Ontario, K1Y 4E9, Canada
    BMC Emerg Med 9:14. 2009
    ..Improving 9-1-1 call takers' ability to recognize agonal breathing as a sign of cardiac arrest could result in improved bystander cardiopulmonary resuscitation and survival rates for out-of-hospital cardiac arrest victims...
  96. pmc A survey of attitudes and factors associated with successful cardiopulmonary resuscitation (CPR) knowledge transfer in an older population most likely to witness cardiac arrest: design and methodology
    Christian Vaillancourt
    Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, Canada
    BMC Emerg Med 8:13. 2008
    ..However, interest in CPR training appears to decrease with advancing age. Behaviour surrounding CPR training and performance has never been studied using well validated behavioural theories...
  97. pmc So what has the Cochrane Collaboration ever done for us? A report card on the first 10 years
    Jeremy Grimshaw
    Clinical Epidemiology Program, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ont
    CMAJ 171:747-9. 2004
  98. ncbi request reprint Is evidence-based implementation of evidence-based care possible?
    Jeremy M Grimshaw
    Clinical Epidemiology Programme, Ottawa Health Research Institute, 1053 Carling Avenue, Ottawa, ON K1Y 4E9, Canada
    Med J Aust 180:S50-1. 2004
    ..Future research is required to develop a better theoretical base and to evaluate further guideline dissemination and implementation strategies...
  99. pmc Applying psychological theories to evidence-based clinical practice: identifying factors predictive of lumbar spine x-ray for low back pain in UK primary care practice
    Jeremy M Grimshaw
    Clinical Epidemiology Programme, Ottawa Health Research Institute and Department of Medicine, University of Ottawa, 1053 Carling Avenue, Administration Building Room 2 017, Ottawa, K1Y 4E9, Canada
    Implement Sci 6:55. 2011
    ....