Research Topics
| Ann B CranneySummaryAffiliation: Ottawa Health Research Institute Country: Canada Publications
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Detail Information
Publications
Do patients perceive a link between a fragility fracture and osteoporosis?Lora Giangregorio
Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada
BMC Musculoskelet Disord 9:38. 2008..To evaluate factors associated with whether patients associate their fracture with future fracture risk...
Physicians' intentions and use of three patient decision aidsIan D Graham
Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, ON, Canada
BMC Med Inform Decis Mak 7:20. 2007..The purpose of this study was to describe physicians' perceptions of three decision aids, their expressed intent to use them, and their subsequent use of them...
Factors predicting osteoporosis treatment initiation in a regionally based cohortA Cranney
Ottawa Health Research Institute, Ottawa, Canada
Osteoporos Int 20:1621-5. 2009..Treatment initiation increased progressively as BMD T-scores decreased, but there was a gradient response rather than step increases at conventional T-score intervention thresholds...
Prospective evaluation of preferences and quality of life in women with hip fracturesAnn B Cranney
Ottawa Health Research Institute, Ottawa, Canada
J Rheumatol 32:2393-9. 2005..We also compared HRQOL in women with recent hip fractures to a control sample at baseline and to normative Canadian data at followup...
Low bone mineral density and fracture burden in postmenopausal womenAnn Cranney
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ont
CMAJ 177:575-80. 2007..5 or less), and to contrast fracture patterns among women 50 to 64 years of age with those among women 65 years of age and older...
Is there a new role for angiotensin-converting-enzyme inhibitors in elderly patients?Ann Cranney
Ottawa Health Research Institute, Ottawa, Ont
CMAJ 177:891-2. 2007
A multifaceted intervention to improve treatment of osteoporosis in postmenopausal women with wrist fractures: a cluster randomized trialA Cranney
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Osteoporos Int 19:1733-40. 2008..Compared to usual care, women in the intervention practices were three times more likely to receive bone mineral density testing and prescribed osteoporosis treatments...
Ibandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient dataA Cranney
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, ON, Canada
Osteoporos Int 20:291-7. 2009..The treatment effect was dose-dependent. Higher doses of ibandronate significantly reduced the risk of nonvertebral fractures more effectively compared with lower doses...
Summary of evidence-based review on vitamin D efficacy and safety in relation to bone healthAnn Cranney
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa Hospital, and The University of Ottawa Evidence based Practice Center, Ottawa, Ontario, Canada
Am J Clin Nutr 88:513S-519S. 2008..We found fair evidence that adults tolerated vitamin D at doses above current dietary reference intake levels, but we had no data on the association between long-term harms and higher doses of vitamin D...
Driving problems in patients with rheumatoid arthritisAnn B Cranney
Ottawa Health Research Institute, Ottawa, Canada
J Rheumatol 32:2337-42. 2005..To assess driving problems experienced by patients with rheumatoid arthritis (RA) and to examine the relationship between functional status and driving difficulty...
Consequences of testing for celiac diseaseAnn Cranney
Ottawa Health Research Institute, Ottawa, Canada
Gastroenterology 128:S109-20. 2005..The literature suggests that compliance is less than ideal in these individuals, especially if diagnosed when adults. Long-term outcomes have not been extensively studied in those with silent CD...
Development and pilot testing of a decision aid for postmenopausal women with osteoporosisAnn Cranney
Department of Medicine, Ottawa Hospital, C4 CEU, 1053 Carling Avenue, Ontario, Canada K1Y4 E9
Patient Educ Couns 47:245-55. 2002..Our decision aid shows promise in preparing women for counseling about osteoporosis therapies. Long-term adherence to chosen therapy and quality of life will be evaluated in a randomized controlled trial...
A qualitative study of physicians' perceptions of three decision aidsIan D Graham
Faculty of Medicine, University of Ottawa, Ont, Canada
Patient Educ Couns 50:279-83. 2003..Uptake of decision aids may be facilitated if physicians have an opportunity to examine and try them, and if they can have unfettered access to them for distribution purposes...
Understanding and overcoming the barriers of implementing patient decision aids in clinical practiceSiobhan O'Donnell
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
J Eval Clin Pract 12:174-81. 2006..This report is based on our interpretation of the literature and our collective experience in implementing ptDAs within trials and other contexts...
Economic evaluation of norethisterone acetate/ethinylestradiol (FemHRT) for women with menopausal symptomsDouglas Coyle
Clinical Epidemiology, Ottawa Health Research Institute, Ottawa Hospital Department of Medicine and Epidemiology, University of Ottawa, Ottawa, Ontario, Canada
Pharmacoeconomics 21:661-9. 2003....
Cost-effectiveness of hip protectors in institutional dwelling elderlyLisa Waldegger
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa Hospital, Ottawa, Ontario, Canada
Osteoporos Int 14:243-50. 2003..Results were robust to a range of analysis exploring the uncertainty of input parameters. CONCLUSIONS: There is sufficient clinical and economic evidence to support the use of hip protectors for institutional dwelling elderly...
Evaluation of in-hospital management of fracture risk in older patients: a chart review study of tertiary preventionAnna M Byszewski
Division of Geriatric Medicine, The Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, Ont, Canada K1Y 4E9
Arch Gerontol Geriatr 42:319-28. 2006..Interventions are required to increase the awareness that this problem is not being addressed at the time of hospitalization and that on discharge, patients will need follow-up by the treating community physician...
The Canadian celiac health survey--the Ottawa chapter pilotAnn Cranney
Division of Rheumatology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
BMC Gastroenterol 3:8. 2003..Our objective was to determine the feasibility of surveying over 5,000 members of the CCA, in addition to obtaining more health related information about celiac disease...
Summary of meta-analyses of therapies for postmenopausal osteoporosis and the relationship between bone density and fracturesGordon H Guyatt
Department of Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada, L8N 3Z5
Endocrinol Metab Clin North Am 31:659-79, xii. 2002..We also outline other important facets of the decision-making process regarding osteoporosis therapy, including attitudes toward uncertainty, circumstances, and patients' and societal preferences...
Efficacy of food fortification on serum 25-hydroxyvitamin D concentrations: systematic reviewSiobhan O'Donnell
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Canada
Am J Clin Nutr 88:1528-34. 2008..Many residents of the United States and Canada depend on dietary sources of vitamin D to help maintain vitamin D status. Because few natural food sources contain vitamin D, fortified foods may be required...
Hormone replacement therapy for postmenopausal osteoporosisAnn Cranney
Division of Rheumatology, Department of Medicine, Queen s University, Etherington Hall, Room 2004, 94 Stuart Street, Kingston, Ontario, Canada, K7L 3N4
Clin Geriatr Med 19:361-70. 2003..The unfavorable risk/benefit profile of HRT, however, strongly limits its use for prevention of osteoporosis, given that there are other medications that have demonstrated fracture efficacy...
The Canadian Celiac Health SurveyAnn Cranney
Department of Medicine, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Dig Dis Sci 52:1087-95. 2007..More accurate food labeling is needed. Improved awareness of celiac disease and greater use of serological screening tests may result in earlier diagnosis and reduced risk of associated conditions...
Corticosteroid-induced osteoporosis: a guide to optimum managementAnn Cranney
Queen's University, Kingston, Ontario, Canada
Treat Endocrinol 1:271-9. 2002..Teriparatide (recombinant human parathyroid hormone 1-34) shows promise as a future anabolic agent for the prevention and treatment of patients with corticosteroid-induced osteoporosis...
Do hip protectors decrease the risk of hip fracture in institutional and community-dwelling elderly? A systematic review and meta-analysis of randomized controlled trialsAnna M Sawka
Division of Endocrinology and Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
Osteoporos Int 16:1461-74. 2005..Thus, there is little evidence to support the use of hip protectors outside the nursing home setting. The potential benefit of hip protectors in reducing hip fractures in nursing home residents requires further confirmation...
Benefit-risk assessment of raloxifene in postmenopausal osteoporosisAnn Cranney
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Drug Saf 28:721-30. 2005..Raloxifene can be recommended for the prevention of vertebral fractures in women with osteopenia/osteoporosis who are not at high risk of non-vertebral fractures and who do not have a past history of venous thromboembolism...
The diagnostic accuracy of serologic tests for celiac disease: a systematic reviewAlaa Rostom
Gastrointestinal Clinical Research Unit, University of Ottawa, Ottawa, Canada
Gastroenterology 128:S38-46. 2005..If true, the nearly perfect negative predictive value of these tests would drop. The positive predictive value of these tests is likely lower than reported when the tests are applied in low-prevalence populations...
Parathyroid hormone for the treatment of osteoporosis: a systematic reviewAnn Cranney
Department of Medicine, University of Ottawa, Ottawa, Ont
CMAJ 175:52-9. 2006....
The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic reviewCatherine Dube
Gastrointestinal Clinical Research Unit, University of Ottawa, Ottawa, Ontario, Canada
Gastroenterology 128:S57-67. 2005..The prevalence is higher still in high-risk groups. Clinicians in a variety of specialties should have a high index of suspicion for the diagnosis of CD and in particular need to pay close attention to the identified high-risk groups...
An unusual case of an enlarged temporal arterySuzan M Attar
Division of Rheumatology, University of Ottawa, The Arthritis Center, Ottawa Hospital Riverside Campus, 1967 Riverside Drive, Box 37, Ottawa, ON K1H 7W9, Canada
J Infect 53:e195-8. 2006..We present an unusual case of a patient with an enlarged temporal artery in the absence of other clinical findings. An atypical biopsy result provided the diagnosis and guided treatment...
Meta-analyses of therapies for postmenopausal osteoporosis. I. Systematic reviews of randomized trials in osteoporosis: introduction and methodologyAnn Cranney
McMaster University, Department of Clinical Epidemiology and Biostatistics, Hamilton, Ontario, Canada
Endocr Rev 23:496-507. 2002
Hip fracture and proton pump inhibitor therapy: balancing the evidence for benefit and harmPaul Moayyedi
Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Am J Gastroenterol 103:2428-31. 2008..The association between proton pump inhibitor therapy and hip fracture is a good illustration of this dilemma. We use this example to highlight an approach that can be taken to critically evaluate the evidence for harms of medication...
