Seymour Brownstein

Summary

Affiliation: Ottawa Health Research Institute
Country: Canada

Publications

  1. ncbi request reprint Melanocytoma of the choroid: atypical presentation and review of the literature
    Seymour Brownstein
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ont
    Can J Ophthalmol 37:247-52. 2002
  2. ncbi request reprint Malignant melanoma of the conjunctiva
    Seymour Brownstein
    Department of Ophthalmology, University of Ottawa Eye Institute, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    Cancer Control 11:310-6. 2004
  3. doi request reprint Myxomatous corneal degeneration: a clinicopathological study of six cases and a review of the literature
    Michel J Belliveau
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Surv Ophthalmol 57:264-71. 2012
  4. ncbi request reprint Clinicopathologic analysis of 15 explanted hydroxyapatite implants
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute, 340 McLeon Street, Suite 104, Ottawa, Ontario K2P 1A4, Canada
    Ophthal Plast Reconstr Surg 20:285-90. 2004
  5. doi request reprint Primary localized conjunctival amyloidosis simulating a lymphoproliferative disorder
    Peter H Spitellie
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 24:417-9. 2008
  6. doi request reprint Comparison of the incidence of opacification of Hydroview hydrogel intraocular lenses with the ophthalmic viscosurgical device used during surgery
    Jeffrey H Sher
    Department of Eye Medicine and Surgery, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Cataract Refract Surg 34:459-64. 2008
  7. doi request reprint Osteogenesis with hematopoiesis simulating infection in a hydroxyapatite orbital implant
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 25:72-4. 2009
  8. ncbi request reprint Cicatricial conjunctival inflammation with trichiasis as the presenting feature of Wegener granulomatosis
    David R Jordan
    University of Ottawa Eye Institute, The Ottawa Hospital, Ontario, Canada
    Ophthal Plast Reconstr Surg 22:69-71. 2006
  9. ncbi request reprint Clinically unsuspected diffuse uveal melanoma presenting as recurrent iritis
    Benjamin Mathew
    Department of Ophthalmology, University of Ottawa Eye Institute, University of Ottawa, The Ottawa Hospital, Ottawa, Ont
    Can J Ophthalmol 39:464-7. 2004
  10. ncbi request reprint Orbital schwannoma: histopathologic correlation with magnetic resonance imaging
    Nigel G Rawlings
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ottawa, Ont
    Can J Ophthalmol 42:326-8. 2007

Collaborators

  • David R Jordan
  • Peter J Kertes
  • Karim F Damji
  • Ramon L Font
  • Ross Milne
  • Guillermo Rocha
  • Michael D O'Connor
  • Daljit Singh
  • R Maarten Egeler
  • W Bruce Jackson
  • Michel J Belliveau
  • Kay Lam
  • Patrick Gooi
  • Jennifer W Robinson
  • Joshua S Manusow
  • Nigel G Rawlings
  • Michael W Dorey
  • Andre Jastrzebski
  • Benjamin Mathew
  • George Mintsioulis
  • Steven Gilberg
  • Vernon Ho Yuen
  • Sherif El-Defrawy
  • Walter Liao
  • Robert Prokopetz
  • Bruce F Burns
  • Pete H Spitellie
  • Devesh K Varma
  • Jeffrey H Sher
  • Peter H Spitellie
  • William G Hodge
  • Aftab Zafar
  • Suleiman O A Sefau
  • Richard Van Der Jagt
  • Michel A Dionne
  • Walter N Liao
  • Shivinder S Jolly
  • Dustin J Coupal
  • Peter Agapitos
  • Hamidreza Faraji
  • Matthew Lee-Wing
  • Bruce Burns
  • William Dubinski
  • Wesley A Nash
  • Diane Chialant
  • Hamid Faraji
  • Gordon K Klintworth
  • Vivian E Hill
  • Ian A Chisholm
  • John M Little
  • Anna Ells
  • Michael E Ashenhurst
  • Gianluigi Botton
  • Wenjun Bao
  • Ken Romanchuk
  • Johannes E A Wolff
  • Steven M Gilberg
  • Baldwin Toye

Detail Information

Publications44

  1. ncbi request reprint Melanocytoma of the choroid: atypical presentation and review of the literature
    Seymour Brownstein
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ont
    Can J Ophthalmol 37:247-52. 2002
  2. ncbi request reprint Malignant melanoma of the conjunctiva
    Seymour Brownstein
    Department of Ophthalmology, University of Ottawa Eye Institute, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    Cancer Control 11:310-6. 2004
    ..Conjunctival melanoma is a relatively rare ocular malignancy with substantial associated morbidity and mortality...
  3. doi request reprint Myxomatous corneal degeneration: a clinicopathological study of six cases and a review of the literature
    Michel J Belliveau
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Surv Ophthalmol 57:264-71. 2012
    ..It remains unclear whether the myxomatous changes in such lesions are neoplastic or degenerative. Myxomatous corneal changes are likely under-recognized and under-diagnosed...
  4. ncbi request reprint Clinicopathologic analysis of 15 explanted hydroxyapatite implants
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute, 340 McLeon Street, Suite 104, Ottawa, Ontario K2P 1A4, Canada
    Ophthal Plast Reconstr Surg 20:285-90. 2004
    ..To report the clinical findings, treatment, outcomes, and histopathologic findings in patients with suspected orbital implant infection requiring implant removal...
  5. doi request reprint Primary localized conjunctival amyloidosis simulating a lymphoproliferative disorder
    Peter H Spitellie
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 24:417-9. 2008
    ..The classic "salmon-pink" conjunctival infitrate has been associated with lymphoproliferative disorders; however, amyloid should also be considered, as it may be clinically indistinguishable...
  6. doi request reprint Comparison of the incidence of opacification of Hydroview hydrogel intraocular lenses with the ophthalmic viscosurgical device used during surgery
    Jeffrey H Sher
    Department of Eye Medicine and Surgery, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Cataract Refract Surg 34:459-64. 2008
    ..To determine the effect of intraoperative ophthalmic viscosurgical devices (OVDs) on late opacification of the Hydroview hydrogel intraocular lens (IOL) (Bausch & Lomb Surgical)...
  7. doi request reprint Osteogenesis with hematopoiesis simulating infection in a hydroxyapatite orbital implant
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 25:72-4. 2009
    ..Extramedullary hematopoiesis within hydroxyapatite implants is rare. Porous orbital implant infection is also rare. Osteogenesis with extramedullary hematopoiesis simulating implant infection has not previously been reported...
  8. ncbi request reprint Cicatricial conjunctival inflammation with trichiasis as the presenting feature of Wegener granulomatosis
    David R Jordan
    University of Ottawa Eye Institute, The Ottawa Hospital, Ontario, Canada
    Ophthal Plast Reconstr Surg 22:69-71. 2006
    ..Although conjunctival involvement in this condition is rare, the diagnosis of Wegener granulomatosis should be suspected when the conjunctival inflammation is recurrent and not typical of other conjunctival inflammatory conditions...
  9. ncbi request reprint Clinically unsuspected diffuse uveal melanoma presenting as recurrent iritis
    Benjamin Mathew
    Department of Ophthalmology, University of Ottawa Eye Institute, University of Ottawa, The Ottawa Hospital, Ottawa, Ont
    Can J Ophthalmol 39:464-7. 2004
  10. ncbi request reprint Orbital schwannoma: histopathologic correlation with magnetic resonance imaging
    Nigel G Rawlings
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ottawa, Ont
    Can J Ophthalmol 42:326-8. 2007
    ..COMMENTS: An array of ancillary studies including orbital ultrasonography may be useful in substantiating the diagnosis preoperatively...
  11. ncbi request reprint Orbital cholesterol granuloma and cholesteatoma: significance of differentiating the two
    David R Jordan
    Department of Ophthalmology Eye Institute, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 23:415-7. 2007
    ..We present a case of each tumor type, illustrating their similarities and highlighting the histopathologic findings and treatment recommendations...
  12. doi request reprint Sinonasal undifferentiated carcinoma with a frozen globe
    Pete H Spitellie
    Department of Ophthalmology, University of Ottawa Eye Institute, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 24:225-7. 2008
    ..The tumor was unresectable and the patient was started on a course of radiation and chemotherapy...
  13. doi request reprint Acanthamoeba keratitis: persistent organisms without inflammation after 1 year of topical chlorhexidine
    Patrick Gooi
    Department of Ophthalmology, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada
    Cornea 27:246-8. 2008
    ..To report a non-contact lens wearer with persistent Acanthamoeba organisms in the cornea after being treated with medical therapy that included topical chlorhexidine as 1 agent for 1 year...
  14. ncbi request reprint An infected porous polyethylene orbital implant
    David R Jordan
    Department of Ophthalmology Eye Institute, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 23:413-5. 2007
    ..With time, and persistence of the symptoms despite numerous treatments, infection should be suspected...
  15. ncbi request reprint An intraocular cilium of uncertain origin
    Peter J Kertes
    University of Ottawa Eye Institute, Ottawa, Ont
    Can J Ophthalmol 39:279-81. 2004
  16. doi request reprint Osseous metaplasia with formation of hematopoietic bone marrow in a blind, painful eye
    Joshua S Manusow
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 27:e81-3. 2011
    ....
  17. doi request reprint Bilateral necrobiotic xanthogranuloma of the eyelids followed by a diagnosis of multiple myeloma 20 years later
    Kay Lam
    Departments of Ophthalmology, Pathology, and Medicine Hematology, University of Ottawa, The Ottawa Hospital, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 29:e119-20. 2013
    ..A review of the literature revealed that this is the longest interval between the onset of the skin manifestations and the diagnosis of the systemic malignancy in this rare disease. ..
  18. ncbi request reprint Generalized posterior keratoconus: clinical pathologic correlations
    Devesh K Varma
    University of Ottawa, Ottawa Hospital Eye Institute, Ottawa, Ontario, Canada
    Can J Ophthalmol 43:480-2. 2008
    ..The corneal thickness measured 0.320 mm paracentrally and 0.440 mm toward the periphery. The corneal specimen revealed absence of Bowman's layer and focal homogeneous oval stromal deposits that stained for amyloid...
  19. doi request reprint Infundibulocystic basal cell carcinoma of the eyelid in basal cell nevus syndrome
    Michel J Belliveau
    Department of Ophthalmology, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 26:147-52. 2010
    ..To describe the histopathologic findings in a series of eyelid basal cell carcinomas removed from patients with basal cell nevus syndrome...
  20. ncbi request reprint Conjunctival mucoepidermoid carcinoma in a patient with ocular cicatricial pemphigoid and a review of the literature
    Jennifer W Robinson
    Department of Ophthalmology, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada
    Surv Ophthalmol 51:513-9. 2006
    ..More extensive surgical excision than that used for squamous cell carcinoma should be implemented in the management of mucoepidermoid carcinoma of the conjunctiva to prevent recurrence...
  21. ncbi request reprint Bilateral benign reactive lymphoid hyperplasia of the conjunctiva in a pediatric patient
    Kay Lam
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    J Pediatr Ophthalmol Strabismus 48:e69-71. 2011
    ..Excisional biopsy of the larger lesion showed a mature, mixed lymphocytic infiltrate with germinal centers, consistent with a diagnosis of benign reactive lymphoid hyperplasia, a rare condition in children...
  22. doi request reprint Lupus miliaris disseminatus faciei of the eyelids: report of two cases
    Walter Liao
    University of Ottawa Eye Institute, The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 26:59-61. 2010
    ..Except for its description as acne agminata by Duke-Elder in 1974, to the authors' knowledge, this condition has not been reported previously in the ophthalmic literature...
  23. doi request reprint Ultrastructural features of posterior crocodile shagreen of the cornea
    Michel J Belliveau
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Surv Ophthalmol 54:569-75. 2009
    ..We believe that posterior crocodile shagreen is most likely a degenerative disorder and that it should be distinguished from central cloudy dystrophy of Fran├žois by its non-familial pattern of occurrence...
  24. doi request reprint Histopathology in a dissecting conjunctival filtering bleb
    Michael D O'Connor
    University of Ottawa Eye Institute, The Ottawa Hospital, Ottawa, Ontario, Canada
    Can J Ophthalmol 43:114-5. 2008
    ..The internal portion of the bleb consisted of loose stromal tissue lacking any internal epithelial lining...
  25. ncbi request reprint Proposed pathogenesis for the delayed postoperative opacification of the hydroview hydrogel intraocular lens
    Michael W Dorey
    Department of Ophthalmology, University of Ottawa Eye Institute, Ontario, Canada
    Am J Ophthalmol 135:591-8. 2003
    ..Interventional case series with clinicopathologic correlation...
  26. ncbi request reprint Merkel cell carcinoma masquerading as a chalazion
    Nigel G Rawlings
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ontario, Canada
    Can J Ophthalmol 42:469-70. 2007
    ..Despite chemotherapy, she succumbed to widespread metastases 13 months later. COMMENTS: MCC must be included in the differential diagnosis of solitary eyelid nodules, requiring early and aggressive treatment...
  27. ncbi request reprint Solitary osseous plasmacytoma of the orbit with amyloidosis
    Nigel G Rawlings
    Department of Ophthalmology, University of Ottawa Eye Institute, The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 23:79-80. 2007
    ..The lesion was diagnosed as a solitary osseous plasmacytoma of the orbit containing amyloid...
  28. ncbi request reprint Infected aluminum oxide orbital implant
    David R Jordan
    University of Ottawa Eye Institute, The Ottawa Hospital, Ontario, Canada
    Ophthal Plast Reconstr Surg 22:66-7. 2006
    ..It is often only with time, a persistence of symptoms and signs, and additional symptoms and signs that implant infection is suspected...
  29. ncbi request reprint One patient with infection at different times of 2 hydroxyapatite implants, each requiring explantation
    David R Jordan
    University of Ottawa Eye Institute, Ottawa, Ont
    Can J Ophthalmol 38:406-9. 2003
  30. doi request reprint Bilateral massive posterior embryotoxon
    Joshua S Manusow
    Department of Ophthalmology and Laboratory Medicine Pathology, University of Ottawa, Ottawa, Ontario, Canada
    J Pediatr Ophthalmol Strabismus 47:e1-3. 2010
    ..The authors believe this case is the largest example of posterior embryotoxon ever published and present a brief review of its associated syndromes...
  31. ncbi request reprint Radiation-induced chorioretinal degeneration: a clinicopathological report of three cases
    Suleiman O A Sefau
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ottawa Ont
    Can J Ophthalmol 38:57-62. 2003
    ..The purpose of this study is to highlight the effects of ionizing radiation on the choroid and to demonstrate how this can result in visual loss, particularly if the macula is involved...
  32. ncbi request reprint Histologic and ultrastructural findings in a case of traumatic graft failure in deep lamellar endothelial keratoplasty: a clinicopathologic case report
    Patrick Gooi
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Cornea 26:853-7. 2007
    ..Although the histopathologic and ultrastructural analysis of a failed DLEK graft has been previously described, we are not aware of any reports of these features in a case of traumatic endothelial graft failure...
  33. ncbi request reprint Bilateral perioptic nerve lesions in a patient with Langerhans-cell histiocytosis
    Vernon Ho Yuen
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, Ont
    Can J Ophthalmol 38:496-500. 2003
  34. ncbi request reprint Conjunctival melanoma in children: a clinicopathologic study of 2 cases
    Seymour Brownstein
    University of Ottawa Eye Institute, Ontario, Canada sbrownstein ohri ca
    Arch Ophthalmol 124:1190-3. 2006
  35. doi request reprint Dacryops: a series of 5 cases and a proposed pathogenesis
    Kay Lam
    Department of Ophthalmology, University of Ottawa, The Ottawa Hospital, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    JAMA Ophthalmol 131:929-32. 2013
    ..Lacrimal gland ductal cysts (dacryops) are uncommon, occurring anywhere that lacrimal gland tissue is present. While dacryops has long been recognized, its pathogenesis has not been well established...
  36. doi request reprint Medial canthal tophus
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 24:403-4. 2008
    ..Gouty tophi are extremely rare in the periocular area but should be considered in the differential diagnosis of basal cell carcinoma as they may have a similar clinical appearance...
  37. ncbi request reprint Corneal myxoma arising in a patient with repeated phototherapeutic keratectomies
    Jennifer W Robinson
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Cornea 25:1111-4. 2006
    ..We report the clinical and pathologic findings of a corneal myxoma that was diagnosed in a cornea that had undergone phototherapeutic keratectomy (PTK)...
  38. ncbi request reprint Topical mitomycin treatment for primary acquired melanosis of the conjunctiva
    Vernon Ho Yuen
    The University of Ottawa Eye Institute, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 19:149-51. 2003
    ..No recurrence of pigmentation was noted in follow-up 26 months after completion of treatment. Topical mitomycin chemotherapy may be a successful primary treatment for primary acquired melanosis of the conjunctiva...
  39. doi request reprint Advanced glycation end products and diabetic retinopathy
    Ross Milne
    University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    Amino Acids 44:1397-407. 2013
    ..AGE inhibitors have been shown to provide protection in animal models of diabetic retinopathy and currently are being evaluated in clinical trials...
  40. ncbi request reprint Unusual superficial variant of granular corneal dystrophy with amyloid deposition
    Benjamin Mathew
    University of Ottawa Eye Institute, 501 Smyth Rd, Room 3818, Ottawa, Ontario, Canada K1H 8L6
    Arch Ophthalmol 121:269-71. 2003
  41. ncbi request reprint Rhodotorula glutinis endophthalmitis
    Michael W Dorey
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa Hospital, Ottawa, Ont
    Can J Ophthalmol 37:416-8. 2002
  42. ncbi request reprint Asymptomatic lacrimal ductule dacryolithiasis with embedded cilia
    Aftab Zafar
    University of Ottawa Eye Institute, Department of Laboratory Medicine Pathology, The Ottawa Hospital, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 20:83-5. 2004
    ..There were several cilia isolated from the dacryolith. This entity should be considered in the differential diagnosis of patients presenting with a localized mass in the region of the lacrimal gland...
  43. ncbi request reprint Investigation of a bioresorbable orbital implant
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa, Ontario, Canada
    Ophthal Plast Reconstr Surg 18:342-8. 2002
    ..To analyze a new bioresorbable orbital implant (open-celled polylactic acid, also known as OPLA)...
  44. ncbi request reprint Hydroxyapatite and calcium phosphate coatings on aluminium oxide orbital implants
    David R Jordan
    Department of Ophthalmology, University of Ottawa Eye Institute, Ont
    Can J Ophthalmol 37:7-13. 2002
    ..We carried out a study to examine uncoated and coated aluminium oxide (alumina) spherical orbital implants and assess whether the coatings influence fibrovascular ingrowth...