Research Topics
| W P OlszynskiSummaryCountry: Canada Publications
| Collaborators
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Detail Information
Publications
Evaluation of easily measured risk factors in the prediction of osteoporotic fracturesRobert Bensen
Medical Science, McMaster University, Hamilton, Ontario, Canada
BMC Musculoskelet Disord 6:47. 2005..As few premonitory symptoms for fracture exist, it is of critical importance that physicians effectively and efficiently identify individuals at increased fracture risk...
Alendronate for the treatment of osteoporosis in menW P Olszynski
University of Saskatchewan, Saskatoon, SK, Canada
Expert Opin Pharmacother 9:491-8. 2008..Men have higher rates of osteoporosis and suffer fragility fractures more often than previously believed. Fracture-related morbidity and mortality in men is substantially higher than in women...
Effectiveness of alendronate and etidronate in the treatment of osteoporosis in men: a prospective observational studyW P Olszynski
Saskatoon Osteoporosis Centre, Saskatoon, SK, S7K 0H6, Canada
Osteoporos Int 17:217-24. 2006..The effect of these two bisphosphonates on fractures and FN BMD in osteoporotic men is likely positive, but requires further study...
Osteoporosis in men: epidemiology, diagnosis, prevention, and treatmentWojciech P Olszynski
Department of Medicine, University of Saskatchewan, Saskatoon Osteoporosis Centre, Saskatoon, Saskatchewan, Canada
Clin Ther 26:15-28. 2004..Osteoporosis and fragility fractures in men account for substantial health care expenditures and decreased quality of life...
The association between osteoporotic fractures and health-related quality of life as measured by the Health Utilities Index in the Canadian Multicentre Osteoporosis Study (CaMos)J D Adachi
Department of Medicine, St Joseph s Hospital, McMaster University, Charlton Avenue East, Suite 501, L8 N 1Y2 Hamilton, Ontario, Canada
Osteoporos Int 14:895-904. 2003..06; 95% CI: -0.11, -0.00) for women, and rib fractures (-0.06; 95% CI: -0.12, -0.00) for men. In conclusion, this study demonstrates a negative association between osteoporotic fractures and quality of life in both women and men...
Construction and validation of a simplified fracture risk assessment tool for Canadian women and men: results from the CaMos and Manitoba cohortsW D Leslie
Department of Medicine, University of Manitoba, Winnipeg, MB, Canada
Osteoporos Int 22:1873-83. 2011..A procedure for creating a simplified version of fracture risk assessment tool (FRAX®) is described. Calibration, fracture prediction, and concordance were compared with the full FRAX tool using two large, complementary Canadian datasets...
Associations among disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results from the Canadian Multicentre Osteoporosis StudyD A Hanley
Department of Medicine, University of Calgary Calgary, Alberta, Canada
J Bone Miner Res 18:784-90. 2003..The importance of these associations for osteoporosis case finding and management require further and prospective studies...
The effectiveness of multidisciplinary rehabilitation in the treatment of fibromyalgia: a randomized controlled trialMark Lemstra
College of Medicine, University of Saskatchewan, Saskatoon, Canada
Clin J Pain 21:166-74. 2005..CONCLUSIONS: Positive health-related outcomes in this mostly unresponsive condition can be obtained with a low-cost, group multidisciplinary intervention in a community-based, nonclinical setting...
Tolerability of risedronate in postmenopausal women intolerant of alendronateJ D Adachi
Department of Medicine, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada
Aging (Milano) 13:347-54. 2001..These results are consistent with, and complement those from previous studies showing that risedronate 5 mg has a gastrointestinal tolerability similar to that of placebo...
The influence of motor vehicle legislation on injury claim incidenceMark Lemstra
College of Medicine, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK S7N 0W8
Can J Public Health 96:65-8. 2005..Legislative system and injury compensation scheme have an observable impact on injury claim incidence and can therefore have significant impact on the health care system...
Development and validation of the Spondyloarthritis Research Consortium of Canada (SPARCC) Enthesitis IndexW P Maksymowych
Department of Medicine, University of Alberta, Canada
Ann Rheum Dis 68:948-53. 2009..Enthesitis is a recommended core domain for assessment of ankylosing spondylitis (AS), but no measurement has yet been validated according to Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) criteria...
The effectiveness of standard care, early intervention, and occupational management in Workers' Compensation claims: part 2Mark Lemstra
College of Medicine, University of Saskatchewan, Saskatoon, Canada
Spine 29:1573-9. 2004..67, 95% confidence interval 1.05-27.20). CONCLUSIONS: It is recommended that an occupational management approach, in comparison to early intervention treatment and standard care, be considered for management of occupational injuries...
Are there differences between men and women prescribed bisphosphonate therapy in canadian subspecialty osteoporosis practices?Anna M Sawka
McMaster University, St Joseph s Healthcare, Centre for Evaluation of Medicines, Hamilton, Ontario, Canada
J Rheumatol 31:1993-5. 2004..To determine if there are differences between men and women referred for treatment of osteoporosis in Canada...
Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agentsClaudie Berger
CaMos Methods Centre, McGill University, Montreal, Que
CMAJ 178:1660-8. 2008..We sought to estimate the average rate of change in bone mineral density as a function of age among Canadians aged 25-85, stratified by sex and use of antiresorptive agents...
Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its useAnthony B Hodsman
University of Western Ontario, St Joseph s Health Care, Room 2F 15, 268, Grosvenor Street, London, Ontario N6A 4V2, Canada
Endocr Rev 26:688-703. 2005..At present, concurrent therapy with antiresorptive therapy, particularly bisphosphonates, should be avoided, although sequential therapy with such agents may consolidate the beneficial effects upon the skeleton after PTH is discontinued...
Are oral bisphosphonates effective in improving lumbar bone mineral density in breast cancer survivors with osteopenia or osteoporosis?Anna M Sawka
Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton ON
J Obstet Gynaecol Can 27:759-64. 2005....
Adherence to bisphosphonates and hormone replacement therapy in a tertiary care setting of patients in the CANDOO databaseAlexandra Papaioannou
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Osteoporos Int 14:808-13. 2003..In conclusion, alendronate users were more likely to discontinue therapy than etidronate users over the follow-up period. Potential barriers to long-term patient adherence to osteoporosis therapies need to be evaluated...
What predicts early fracture or bone loss on bisphosphonate therapy?Anna M Sawka
McMaster University, Hamilton, ON, CA
J Clin Densitom 6:315-22. 2003..13, 0.62, p = 0.002). In conclusion, early fracture on bisphosphonate therapy is most strongly predicted by a previous history of fracture and early bone loss is most strongly predicted by the potency of the prescribed bisphosphonate...
Risk factors associated with incident clinical vertebral and nonvertebral fractures in postmenopausal women: the Canadian Multicentre Osteoporosis Study (CaMos)Alexandra Papaioannou
Department of Medicine, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada
Osteoporos Int 16:568-78. 2005..Furthermore, various anthropometric measures, disease conditions, and medications are associated with a new fracture. Identifying postmenopausal women at risk is important given that fracture prevention therapies are now available...
Standards and guidelines for performing central dual-energy x-ray absorptiometry in premenopausal women, men, and childrenAliya A Khan
Divisions of Endocrinology and Geriatrics, McMaster University, Hamilton, ON, Canada
J Clin Densitom 7:51-64. 2004..Previously, this group addressed the performance of densitometry in postmenopausal women. This report addresses the use of densitometry in men, premenopausal women, and children with a focus on dual-energy X-ray absorptiometry...
Quantitative ultrasound in the management of osteoporosis: the 2007 ISCD Official PositionsMarc Antoine Krieg
Lausanne University Hospital, Lausanne, Switzerland
J Clin Densitom 11:163-87. 2008..The ISCD Official Positions on QUS resulting from this PDC, the rationale for their establishment, and recommendations for further study are presented here...
The 2002 Canadian bone densitometry recommendations: take-home messagesAliya A Khan
Division of Geriatrics, McMaster University, Hamilton, ON
CMAJ 167:1141-5. 2002
Management of osteoporosis in men: an update and case exampleAliya A Khan
Division of Endocrinology and Geriatrics, Department of Medicine, McMaster University, Hamilton, Ont
CMAJ 176:345-8. 2007..The current paper supplements that guideline and provides a review and synthesis of the current literature on the diagnosis and management of osteoporosis in men...
Bone strength: the whole is greater than the sum of its partsK Shawn Davison
Clinical Research Scientist, Department of Medicine, Laval University, Sainte Foy, Quebec, Canada
Semin Arthritis Rheum 36:22-31. 2006..To summarize the current knowledge regarding the various determinants of bone strength...
The effects of antifracture therapies on the components of bone strength: assessment of fracture risk today and in the futureK Shawn Davison
Clinical Research Scientist, Department of Medicine, Laval University, Sainte Foy, Quebec, Canada
Semin Arthritis Rheum 36:10-21. 2006..To summarize the current knowledge regarding the impact of the most common antifracture medications on the various determinants of bone strength...
Standards for performing DXA in individuals with secondary causes of osteoporosisAliya A Khan
Division of Endocrinology, McMaster University, Hamilton, Ontario, Canada, and Hanover General Hospital, PA, USA
J Clin Densitom 9:47-57. 2006..Dual-energy X-ray absorptiometry is a valuable tool in assessing skeletal health in individuals with secondary causes of osteoporosis...
