Research Topics
Species | John G HanlySummaryAffiliation: Nova Scotia Country: Canada Publications
| Collaborators
|
Detail Information
Publications
Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort studyJohn G Hanly
Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
Ann Rheum Dis 71:1502-9. 2012..The aim of this study was to describe the frequency, attribution, outcome and predictors of seizures in systemic lupus erythematosus (SLE)...- Screening for cognitive impairment in systemic lupus erythematosusJohn G Hanly
Division of Rheumatology, Nova Scotia Rehabilitation Centre, 2nd Floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
J Rheumatol 39:1371-7. 2012..We examined the association between responses on a screening questionnaire and objective performance on a computer-administered test of cognitive abilities in systemic lupus erythematosus (SLE)... 
Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunityJoan Wither
Arthritis Centre of Excellence, Division of Genetics and Development, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
Arthritis Res Ther 10:R108. 2008..Here, we used flow cytometry to investigate whether some of the immune abnormalities that are seen in the peripheral blood lymphocyte population of lupus patients are seen in their first-degree relatives...
New insights into central nervous system lupus: a clinical perspectiveJohn G Hanly
Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada, B3H 4K4
Curr Rheumatol Rep 9:116-24. 2007..Therapeutic options include symptomatic therapies, immunosuppression, and anticoagulation...- Autoantibodies and neuropsychiatric events at the time of systemic lupus erythematosus diagnosis: results from an international inception cohort studyJ G Hanly
Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
Arthritis Rheum 58:843-53. 2008.... - Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort studyJ G Hanly
Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
Arthritis Rheum 59:721-9. 2008..To determine the short-term outcome of neuropsychiatric (NP) events upon enrollment into an international inception cohort of patients with systemic lupus erythematosus (SLE)... - Gout in the elderly--a population health studyJohn G Hanly
Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre, College of Pharmacy, Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
J Rheumatol 36:822-30. 2009..To determine the incidence, healthcare utilization, and costs in older adults with gout... - Prospective analysis of neuropsychiatric events in an international disease inception cohort of patients with systemic lupus erythematosusJ G Hanly
Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
Ann Rheum Dis 69:529-35. 2010..To determine the frequency, accrual, attribution and outcome of neuropsychiatric (NP) events and impact on quality of life over 3 years in a large inception cohort of patients with systemic lupus erythematosus (SLE)... - Prospective study of neuropsychiatric events in systemic lupus erythematosusJohn G Hanly
Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
J Rheumatol 36:1449-59. 2009..To prospectively examine neuropsychiatric (NP) events and their association with health related quality of life (HRQOL) over time in patients with systemic lupus erythematosus (SLE)... - Measurement of autoantibodies using multiplex methodology in patients with systemic lupus erythematosusJohn G Hanly
Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
J Immunol Methods 352:147-52. 2010..012). This was confirmed by multivariate analysis (p=0.047). These results suggest reasonable agreement between the detection of lupus autoantibodies by ELISA and BioPlex. The latter demonstrated a better correlation with lupus nephritis... - Demystifying neuropsychiatric lupus--is it possible?John G Hanly
Division of Rheumatology, Department of Medicine and Department of Pathology, Capital Health and Dalhousie University, Halifax, Nova Scotia, Canada
Bull NYU Hosp Jt Dis 67:276-80. 2009..Although much work remains to be done on this complex and fascinating aspect of lupus, there is an emerging consensus on the pathogenesis and treatment of NP-SLE... - Assessment of cognitive function in systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis by computerized neuropsychological testsJohn G Hanly
Dalhousie University, Halifax, Nova Scotia, Canada
Arthritis Rheum 62:1478-86. 2010..This study was undertaken to compare patients with SLE, patients with rheumatoid arthritis (RA), and patients with multiple sclerosis (MS) with healthy controls using the Automated Neuropsychological Assessment Metrics (ANAM)... - Comparison between multiplex assays for autoantibody detection in systemic lupus erythematosusJohn G Hanly
Division of Rheumatology, Capital Health and Dalhousie University, Halifax, Nova Scotia, Canada
J Immunol Methods 358:75-80. 2010..Furthermore, there were differences between assays in their associations with global SLE disease activity and lupus nephritis... - SF-36 summary and subscale scores are reliable outcomes of neuropsychiatric events in systemic lupus erythematosusJ G Hanly
Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, NS B3H 4K4, Canada
Ann Rheum Dis 70:961-7. 2011..To examine change in health-related quality of life in association with clinical outcomes of neuropsychiatric events in systemic lupus erythematosus (SLE)... - Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosusJ G Hanly
Department of Medicine, Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
Ann Rheum Dis 70:1726-32. 2011..This study examined a disease inception cohort of 1047 SLE patients to determine which autoantibodies at enrolment predicted subsequent neuropsychiatric events... - Neuropsychiatric events at the time of diagnosis of systemic lupus erythematosus: an international inception cohort studyJ G Hanly
Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
Arthritis Rheum 56:265-73. 2007..To describe the prevalence, characteristics, attribution, and clinical significance of neuropsychiatric (NP) events in an international inception cohort of systemic lupus erythematosus (SLE) patients... - Anti-NR2 glutamate receptor antibodies and cognitive function in systemic lupus erythematosusJohn G Hanly
Division of Rheumatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 33:1553-8. 2006..To determine the prevalence of circulating anti-NR2 antibodies and their association with neuropsychiatric systemic lupus erythematosus (NP-SLE), particularly cognitive function, in women with SLE... - Tribute: John Francis Lydiard "Jack" WoodburyJohn G Hanly
Division of Rheumatology, Arthritis Centre of Nova Scotia, Canada
J Rheumatol 33:368. 2006 - Antiphospholipid syndrome: an overviewJohn G Hanly
Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS
CMAJ 168:1675-82. 2003..The mainstay of therapy is anticoagulation, whereas immunosuppression is ineffective... - Management of neuropsychiatric lupusJohn G Hanly
Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada B3H 4K4
Best Pract Res Clin Rheumatol 19:799-821. 2005..In the absence of controlled studies, the use of symptomatic therapies, immunosuppressives, anticoagulants and non-pharmacologic interventions is supported by case series and clinical experience... - Neuropsychiatric events in systemic lupus erythematosus: attribution and clinical significanceJohn G Hanly
Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 31:2156-62. 2004.... - Neuropsychiatric syndromes in patients with systemic lupus erythematosus and rheumatoid arthritisJohn G Hanly
Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 32:1459-6. 2005..We compared the prevalence, diversity, and clinical significance of NP syndromes in patients with SLE and rheumatoid arthritis (RA)... - Neuropsychiatric lupusJohn G Hanly
Division of Rheumatology, Arthritis Center of Nova Scotia, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS B3H 4K4, Canada
Rheum Dis Clin North Am 31:273-98, vi. 2005..Treatment remains largely empiric in the absence of controlled studies, and current strategies include the use of immunosuppressive therapies, appropriate symptomatic interventions, and the treatment of non-SLE factors... - ACR classification criteria for systemic lupus erythematosus: limitations and revisions to neuropsychiatric variablesJ G Hanly
Department of Medicine, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada, B3H 4K4
Lupus 13:861-4. 2004.... - Impact of a rheumatology consultation service on the diagnostic accuracy and management of gout in hospitalized patientsClaire Barber
Division of Rheumatology, Nova Scotia Rehabilitation Centre, Halifax, Nova Scotia
J Rheumatol 36:1699-704. 2009..To determine if a hospital rheumatology consultation service improves diagnostic accuracy and adherence to treatment recommendations for gout... - Inhibition of annexin V binding to cardiolipin and thrombin generation in an unselected population with venous thrombosisJohn G Hanly
Divisions of Rheumatology and Hematology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, 1341 Summer Street, Halifax, Nova Scotia, Canada B3H 4K4
J Rheumatol 30:1990-3. 2003..CONCLUSION: Our findings suggest that subtle abnormalities in annexin V physiology may contribute to the procoagulant state in patients with idiopathic venous thrombosis... - The accuracy of administrative data diagnoses of systemic autoimmune rheumatic diseasesSasha Bernatsky
Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre MUHC, Montreal, Quebec, Canada
J Rheumatol 38:1612-6. 2011.... - Cocaine-related retiform purpura: evidence to incriminate the adulterant, levamisoleNoreen M G Walsh
Department of Pathology, Capital District Health Authority and Dalhousie University, 5788 University Avenue, Halifax, Nova Scotia, Canada
J Cutan Pathol 37:1212-9. 2010..Urine toxicology shortly after a binge of cocaine use in each case was positive for levamisole... - Physician resources and postgraduate training in canadian academic rheumatology centers: a 5-year prospective studyJohn G Hanly
Canadian Council of Academic Rheumatologists and Dalhousie University, Halifax, Canada
J Rheumatol 31:1200-5. 2004..Enrollment in rheumatology training programs is falling and is insufficient to meet the present and future needs for patients with rheumatic diseases in Canada... - Meningeal involvement in Wegener's granulomatosisAli Al Dhanhani
Division of Rheumatology, Department of Medicine, the Division of Anatomical Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 33:364-7. 2006..This rare neurological manifestation of WG was treated successfully with oral cyclophosphamide and the patient has continued remission for 3 years taking oral methotrexate... - Factor V Leiden, prothrombin gene mutation, and thrombosis risk in patients with antiphospholipid antibodiesNikhil Chopra
Division of Rheumatology, Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 29:1683-8. 2002.... - Neuropsychiatric lupusJ G Hanly
Division of Rheumatology, Queen Elizabeth II Health Sciences Center, 310 Bethune Building, Halifax, Nova Scotia, B3H 2Y9, Canada
Curr Rheumatol Rep 3:205-12. 2001..Multicenter initiatives are required to address important issues on prognosis and management... - Anti-beta2-glycoprotein I autoantibodies, in vitro thrombin generation, and the antiphospholipid syndromeJ G Hanly
Department of Medicine, Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 27:2152-9. 2000.... - Efficacy of sacroiliac corticosteroid injections in patients with inflammatory spondyloarthropathy: results of a 6 month controlled studyJ G Hanly
Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
J Rheumatol 27:719-22. 2000..To evaluate changes in articular symptoms, spinal mobility, and global function over 6 months after intraarticular injections of long acting corticosteroid into the sacroiliac (SI) joints of patients with inflammatory low back pain (ILBP)... - Association of autoantibodies to nuclear lamin B1 with thromboprotection in systemic lupus erythematosus: lack of evidence for a direct role of lamin B1 in apoptotic blebsMélanie Dieudé
Autoimmunity Research Laboratory, Notre Dame Hospital, Centre Hospitalier de l Universite de Montreal, 1560 Sherbrooke Street East, Montreal, Quebec H2L 4M1, Canada
Arthritis Rheum 46:2695-707. 2002.... - Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal responseMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1789-95. 2008..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis... - Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response indexMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1784-8. 2008..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index...