John G Hanly

Summary

Affiliation: Nova Scotia
Country: Canada

Publications

  1. doi Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort study
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    Ann Rheum Dis 71:1502-9. 2012
  2. doi Screening for cognitive impairment in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre, 2nd Floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 39:1371-7. 2012
  3. pmc Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
    Joan Wither
    Arthritis Centre of Excellence, Division of Genetics and Development, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    Arthritis Res Ther 10:R108. 2008
  4. doi Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosus
    J G Hanly
    Department of Medicine, Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Rheum Dis 70:1726-32. 2011
  5. ncbi New insights into central nervous system lupus: a clinical perspective
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada, B3H 4K4
    Curr Rheumatol Rep 9:116-24. 2007
  6. ncbi Autoantibodies and neuropsychiatric events at the time of systemic lupus erythematosus diagnosis: results from an international inception cohort study
    J G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Arthritis Rheum 58:843-53. 2008
  7. ncbi Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
    Arthritis Rheum 59:721-9. 2008
  8. doi Gout in the elderly--a population health study
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre, College of Pharmacy, Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 36:822-30. 2009
  9. pmc Prospective analysis of neuropsychiatric events in an international disease inception cohort of patients with systemic lupus erythematosus
    J G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Rheum Dis 69:529-35. 2010
  10. ncbi Prospective study of neuropsychiatric events in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 36:1449-59. 2009

Collaborators

Detail Information

Publications40

  1. doi Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort study
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    Ann Rheum Dis 71:1502-9. 2012
    ..The aim of this study was to describe the frequency, attribution, outcome and predictors of seizures in systemic lupus erythematosus (SLE)...
  2. doi Screening for cognitive impairment in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre, 2nd Floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 39:1371-7. 2012
    ..We examined the association between responses on a screening questionnaire and objective performance on a computer-administered test of cognitive abilities in systemic lupus erythematosus (SLE)...
  3. pmc Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
    Joan Wither
    Arthritis Centre of Excellence, Division of Genetics and Development, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    Arthritis Res Ther 10:R108. 2008
    ..Here, we used flow cytometry to investigate whether some of the immune abnormalities that are seen in the peripheral blood lymphocyte population of lupus patients are seen in their first-degree relatives...
  4. doi Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosus
    J G Hanly
    Department of Medicine, Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Rheum Dis 70:1726-32. 2011
    ..This study examined a disease inception cohort of 1047 SLE patients to determine which autoantibodies at enrolment predicted subsequent neuropsychiatric events...
  5. ncbi New insights into central nervous system lupus: a clinical perspective
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada, B3H 4K4
    Curr Rheumatol Rep 9:116-24. 2007
    ..Therapeutic options include symptomatic therapies, immunosuppression, and anticoagulation...
  6. ncbi Autoantibodies and neuropsychiatric events at the time of systemic lupus erythematosus diagnosis: results from an international inception cohort study
    J G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Arthritis Rheum 58:843-53. 2008
    ....
  7. ncbi Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
    Arthritis Rheum 59:721-9. 2008
    ..To determine the short-term outcome of neuropsychiatric (NP) events upon enrollment into an international inception cohort of patients with systemic lupus erythematosus (SLE)...
  8. doi Gout in the elderly--a population health study
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre, College of Pharmacy, Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 36:822-30. 2009
    ..To determine the incidence, healthcare utilization, and costs in older adults with gout...
  9. pmc Prospective analysis of neuropsychiatric events in an international disease inception cohort of patients with systemic lupus erythematosus
    J G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Rheum Dis 69:529-35. 2010
    ..To determine the frequency, accrual, attribution and outcome of neuropsychiatric (NP) events and impact on quality of life over 3 years in a large inception cohort of patients with systemic lupus erythematosus (SLE)...
  10. ncbi Prospective study of neuropsychiatric events in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 36:1449-59. 2009
    ..To prospectively examine neuropsychiatric (NP) events and their association with health related quality of life (HRQOL) over time in patients with systemic lupus erythematosus (SLE)...
  11. ncbi Measurement of autoantibodies using multiplex methodology in patients with systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Immunol Methods 352:147-52. 2010
    ..012). This was confirmed by multivariate analysis (p=0.047). These results suggest reasonable agreement between the detection of lupus autoantibodies by ELISA and BioPlex. The latter demonstrated a better correlation with lupus nephritis...
  12. ncbi Demystifying neuropsychiatric lupus--is it possible?
    John G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Capital Health and Dalhousie University, Halifax, Nova Scotia, Canada
    Bull NYU Hosp Jt Dis 67:276-80. 2009
    ..Although much work remains to be done on this complex and fascinating aspect of lupus, there is an emerging consensus on the pathogenesis and treatment of NP-SLE...
  13. ncbi Assessment of cognitive function in systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis by computerized neuropsychological tests
    John G Hanly
    Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 62:1478-86. 2010
    ..This study was undertaken to compare patients with SLE, patients with rheumatoid arthritis (RA), and patients with multiple sclerosis (MS) with healthy controls using the Automated Neuropsychological Assessment Metrics (ANAM)...
  14. ncbi Comparison between multiplex assays for autoantibody detection in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Capital Health and Dalhousie University, Halifax, Nova Scotia, Canada
    J Immunol Methods 358:75-80. 2010
    ..Furthermore, there were differences between assays in their associations with global SLE disease activity and lupus nephritis...
  15. pmc SF-36 summary and subscale scores are reliable outcomes of neuropsychiatric events in systemic lupus erythematosus
    J G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, NS B3H 4K4, Canada
    Ann Rheum Dis 70:961-7. 2011
    ..To examine change in health-related quality of life in association with clinical outcomes of neuropsychiatric events in systemic lupus erythematosus (SLE)...
  16. ncbi Neuropsychiatric events at the time of diagnosis of systemic lupus erythematosus: an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 56:265-73. 2007
    ..To describe the prevalence, characteristics, attribution, and clinical significance of neuropsychiatric (NP) events in an international inception cohort of systemic lupus erythematosus (SLE) patients...
  17. ncbi Anti-NR2 glutamate receptor antibodies and cognitive function in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 33:1553-8. 2006
    ..To determine the prevalence of circulating anti-NR2 antibodies and their association with neuropsychiatric systemic lupus erythematosus (NP-SLE), particularly cognitive function, in women with SLE...
  18. ncbi Tribute: John Francis Lydiard "Jack" Woodbury
    John G Hanly
    Division of Rheumatology, Arthritis Centre of Nova Scotia, Canada
    J Rheumatol 33:368. 2006
  19. ncbi Management of neuropsychiatric lupus
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada B3H 4K4
    Best Pract Res Clin Rheumatol 19:799-821. 2005
    ..In the absence of controlled studies, the use of symptomatic therapies, immunosuppressives, anticoagulants and non-pharmacologic interventions is supported by case series and clinical experience...
  20. ncbi Neuropsychiatric syndromes in patients with systemic lupus erythematosus and rheumatoid arthritis
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 32:1459-6. 2005
    ..We compared the prevalence, diversity, and clinical significance of NP syndromes in patients with SLE and rheumatoid arthritis (RA)...
  21. ncbi Neuropsychiatric lupus
    John G Hanly
    Division of Rheumatology, Arthritis Center of Nova Scotia, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS B3H 4K4, Canada
    Rheum Dis Clin North Am 31:273-98, vi. 2005
    ..Treatment remains largely empiric in the absence of controlled studies, and current strategies include the use of immunosuppressive therapies, appropriate symptomatic interventions, and the treatment of non-SLE factors...
  22. ncbi ACR classification criteria for systemic lupus erythematosus: limitations and revisions to neuropsychiatric variables
    J G Hanly
    Department of Medicine, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada, B3H 4K4
    Lupus 13:861-4. 2004
    ....
  23. ncbi Neuropsychiatric events in systemic lupus erythematosus: attribution and clinical significance
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 31:2156-62. 2004
    ....
  24. pmc Antiphospholipid syndrome: an overview
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS
    CMAJ 168:1675-82. 2003
    ..The mainstay of therapy is anticoagulation, whereas immunosuppression is ineffective...
  25. ncbi Headache in systemic lupus erythematosus: results from a prospective, international inception cohort study
    John G Hanly
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 65:2887-97. 2013
    ..To examine the frequency and characteristics of headaches and their association with global disease activity and health-related quality of life (HRQOL) in patients with systemic lupus erythematosus (SLE)...
  26. ncbi American College of Rheumatology Criteria at Inception, and Accrual over 5 Years in the SLICC Inception Cohort
    Murray B Urowitz
    From the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK Department of Rheumatology, Hospital for Rheumatic Diseases and Hanyang University Medical Center, Seoul, Korea Divisions of Clinical Immunology Allergy and Clinical Epidemiology, Montreal General Hospital and McGill University Health Centre, Montreal, Quebec, Canada Centre Hospitalier Universitaire de Québec et Université Laval, Quebec City, Quebec, Canada Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada Centre for Rheumatology Research, University College, London, UK Cedars Sinai David Geffen School of Medicine, University of California, Los Angeles, California, USA Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, USA Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre
    J Rheumatol 41:875-80. 2014
    ..To determine the frequency of each American College of Rheumatology (ACR) criterion met at time of enrollment, and the increase in each of the criteria over 5 years...
  27. doi Impact of a rheumatology consultation service on the diagnostic accuracy and management of gout in hospitalized patients
    Claire Barber
    Division of Rheumatology, Nova Scotia Rehabilitation Centre, Halifax, Nova Scotia
    J Rheumatol 36:1699-704. 2009
    ..To determine if a hospital rheumatology consultation service improves diagnostic accuracy and adherence to treatment recommendations for gout...
  28. ncbi Inhibition of annexin V binding to cardiolipin and thrombin generation in an unselected population with venous thrombosis
    John G Hanly
    Divisions of Rheumatology and Hematology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, 1341 Summer Street, Halifax, Nova Scotia, Canada B3H 4K4
    J Rheumatol 30:1990-3. 2003
    ..The prevalence of autoimmune antiphospholipid antibodies (aPL) was also determined...
  29. doi The accuracy of administrative data diagnoses of systemic autoimmune rheumatic diseases
    Sasha Bernatsky
    Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre MUHC, Montreal, Quebec, Canada
    J Rheumatol 38:1612-6. 2011
    ....
  30. ncbi Physician resources and postgraduate training in canadian academic rheumatology centers: a 5-year prospective study
    John G Hanly
    Canadian Council of Academic Rheumatologists and Dalhousie University, Halifax, Canada
    J Rheumatol 31:1200-5. 2004
    ..To describe the trends in physician resources, changes in activity profiles, and the output of the postgraduate training programs in Canadian academic rheumatology centers from 1998-2002...
  31. doi Cocaine-related retiform purpura: evidence to incriminate the adulterant, levamisole
    Noreen M G Walsh
    Department of Pathology, Capital District Health Authority and Dalhousie University, 5788 University Avenue, Halifax, Nova Scotia, Canada
    J Cutan Pathol 37:1212-9. 2010
    ..Urine toxicology shortly after a binge of cocaine use in each case was positive for levamisole...
  32. ncbi Systemic autoimmune rheumatic disease prevalence in Canada: updated analyses across 7 provinces
    Laurel Broten
    From the Division of Clinical Epidemiology, and Divisions of Rheumatology, and Clinical Immunology Allergy, Research Institute of the McGill University Health Centre MUHC, Montreal, Quebec Division of Rheumatology, University of British Columbia, Vancouver, British Columbia Department of Epidemiology and Biostatistics, and Division of Rheumatology, McGill University Dalhousie University and Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia Departments of Medicine and Community Health Sciences, University of Manitoba, and Repository, Manitoba Centre for Health Policy, Winnipeg, Manitoba Centre for Chronic Disease Prevention, Public Health Agency of Canada, Ottawa, Ontario Division of Rheumatology, University of Calgary, Calgary, Alberta Centre de recherche du CHU de Québec, Faculte de Medecine, Universite Laval, Quebec City, Quebec Chronic Disease Surveillance Division, National Institute of Public Health of Québec Health Surveillance Branch, Public Health Division, Alberta Health and Wellness, Edmonton, Alberta Divisions of Rheumatology, and Clinical Immunology Allergy, Research Institute of the MUHC Canadian Arthritis Patient Alliance Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    J Rheumatol 41:673-9. 2014
    ..To estimate systemic autoimmune rheumatic disease (SARD) prevalence across 7 Canadian provinces using population-based administrative data evaluating both regional variations and the effects of age and sex...
  33. ncbi Meningeal involvement in Wegener's granulomatosis
    Ali Al Dhanhani
    Division of Rheumatology, Department of Medicine, the Division of Anatomical Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 33:364-7. 2006
    ..This rare neurological manifestation of WG was treated successfully with oral cyclophosphamide and the patient has continued remission for 3 years taking oral methotrexate...
  34. ncbi Factor V Leiden, prothrombin gene mutation, and thrombosis risk in patients with antiphospholipid antibodies
    Nikhil Chopra
    Division of Rheumatology, Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 29:1683-8. 2002
    ....
  35. ncbi Neuropsychiatric lupus
    J G Hanly
    Division of Rheumatology, Queen Elizabeth II Health Sciences Center, 310 Bethune Building, Halifax, Nova Scotia, B3H 2Y9, Canada
    Curr Rheumatol Rep 3:205-12. 2001
    ..Multicenter initiatives are required to address important issues on prognosis and management...
  36. ncbi Efficacy of sacroiliac corticosteroid injections in patients with inflammatory spondyloarthropathy: results of a 6 month controlled study
    J G Hanly
    Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 27:719-22. 2000
    ..To evaluate changes in articular symptoms, spinal mobility, and global function over 6 months after intraarticular injections of long acting corticosteroid into the sacroiliac (SI) joints of patients with inflammatory low back pain (ILBP)...
  37. ncbi Anti-beta2-glycoprotein I autoantibodies, in vitro thrombin generation, and the antiphospholipid syndrome
    J G Hanly
    Department of Medicine, Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 27:2152-9. 2000
    ....
  38. ncbi Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response index
    Michelle Petri
    Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Arthritis Rheum 58:1784-8. 2008
    ..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index...
  39. ncbi Association of autoantibodies to nuclear lamin B1 with thromboprotection in systemic lupus erythematosus: lack of evidence for a direct role of lamin B1 in apoptotic blebs
    Mélanie Dieudé
    Autoimmunity Research Laboratory, Notre Dame Hospital, Centre Hospitalier de l Universite de Montreal, 1560 Sherbrooke Street East, Montreal, Quebec H2L 4M1, Canada
    Arthritis Rheum 46:2695-707. 2002
    ....
  40. ncbi Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal response
    Michelle Petri
    Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Arthritis Rheum 58:1789-95. 2008
    ..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis...