John G Hanly

Summary

Affiliation: Nova Scotia
Country: Canada

Publications

  1. doi request reprint Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort study
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    Ann Rheum Dis 71:1502-9. 2012
  2. doi request reprint Screening for cognitive impairment in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre, 2nd Floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 39:1371-7. 2012
  3. pmc Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
    Joan Wither
    Arthritis Centre of Excellence, Division of Genetics and Development, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    Arthritis Res Ther 10:R108. 2008
  4. doi request reprint Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
    Arthritis Rheum 59:721-9. 2008
  5. ncbi request reprint Tribute: John Francis Lydiard "Jack" Woodbury
    John G Hanly
    Division of Rheumatology, Arthritis Centre of Nova Scotia, Canada
    J Rheumatol 33:368. 2006
  6. ncbi request reprint Anti-NR2 glutamate receptor antibodies and cognitive function in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 33:1553-8. 2006
  7. ncbi request reprint Neuropsychiatric events at the time of diagnosis of systemic lupus erythematosus: an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 56:265-73. 2007
  8. ncbi request reprint New insights into central nervous system lupus: a clinical perspective
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada, B3H 4K4
    Curr Rheumatol Rep 9:116-24. 2007
  9. doi request reprint Autoantibodies and neuropsychiatric events at the time of systemic lupus erythematosus diagnosis: results from an international inception cohort study
    J G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Arthritis Rheum 58:843-53. 2008
  10. doi request reprint Measurement of autoantibodies using multiplex methodology in patients with systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Immunol Methods 352:147-52. 2010

Collaborators

Detail Information

Publications38

  1. doi request reprint Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort study
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    Ann Rheum Dis 71:1502-9. 2012
    ..The aim of this study was to describe the frequency, attribution, outcome and predictors of seizures in systemic lupus erythematosus (SLE)...
  2. doi request reprint Screening for cognitive impairment in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre, 2nd Floor, 1341 Summer Street, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 39:1371-7. 2012
    ..We examined the association between responses on a screening questionnaire and objective performance on a computer-administered test of cognitive abilities in systemic lupus erythematosus (SLE)...
  3. pmc Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
    Joan Wither
    Arthritis Centre of Excellence, Division of Genetics and Development, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    Arthritis Res Ther 10:R108. 2008
    ..Here, we used flow cytometry to investigate whether some of the immune abnormalities that are seen in the peripheral blood lymphocyte population of lupus patients are seen in their first-degree relatives...
  4. doi request reprint Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
    Arthritis Rheum 59:721-9. 2008
    ..To determine the short-term outcome of neuropsychiatric (NP) events upon enrollment into an international inception cohort of patients with systemic lupus erythematosus (SLE)...
  5. ncbi request reprint Tribute: John Francis Lydiard "Jack" Woodbury
    John G Hanly
    Division of Rheumatology, Arthritis Centre of Nova Scotia, Canada
    J Rheumatol 33:368. 2006
  6. ncbi request reprint Anti-NR2 glutamate receptor antibodies and cognitive function in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 33:1553-8. 2006
    ..To determine the prevalence of circulating anti-NR2 antibodies and their association with neuropsychiatric systemic lupus erythematosus (NP-SLE), particularly cognitive function, in women with SLE...
  7. ncbi request reprint Neuropsychiatric events at the time of diagnosis of systemic lupus erythematosus: an international inception cohort study
    J G Hanly
    Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 56:265-73. 2007
    ..To describe the prevalence, characteristics, attribution, and clinical significance of neuropsychiatric (NP) events in an international inception cohort of systemic lupus erythematosus (SLE) patients...
  8. ncbi request reprint New insights into central nervous system lupus: a clinical perspective
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada, B3H 4K4
    Curr Rheumatol Rep 9:116-24. 2007
    ..Therapeutic options include symptomatic therapies, immunosuppression, and anticoagulation...
  9. doi request reprint Autoantibodies and neuropsychiatric events at the time of systemic lupus erythematosus diagnosis: results from an international inception cohort study
    J G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Arthritis Rheum 58:843-53. 2008
    ....
  10. doi request reprint Measurement of autoantibodies using multiplex methodology in patients with systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Immunol Methods 352:147-52. 2010
    ..012). This was confirmed by multivariate analysis (p=0.047). These results suggest reasonable agreement between the detection of lupus autoantibodies by ELISA and BioPlex. The latter demonstrated a better correlation with lupus nephritis...
  11. doi request reprint Prospective study of neuropsychiatric events in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 36:1449-59. 2009
    ..To prospectively examine neuropsychiatric (NP) events and their association with health related quality of life (HRQOL) over time in patients with systemic lupus erythematosus (SLE)...
  12. pmc Prospective analysis of neuropsychiatric events in an international disease inception cohort of patients with systemic lupus erythematosus
    J G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Rheum Dis 69:529-35. 2010
    ..To determine the frequency, accrual, attribution and outcome of neuropsychiatric (NP) events and impact on quality of life over 3 years in a large inception cohort of patients with systemic lupus erythematosus (SLE)...
  13. ncbi request reprint Demystifying neuropsychiatric lupus--is it possible?
    John G Hanly
    Division of Rheumatology, Department of Medicine and Department of Pathology, Capital Health and Dalhousie University, Halifax, Nova Scotia, Canada
    Bull NYU Hosp Jt Dis 67:276-80. 2009
    ..Although much work remains to be done on this complex and fascinating aspect of lupus, there is an emerging consensus on the pathogenesis and treatment of NP-SLE...
  14. ncbi request reprint Management of neuropsychiatric lupus
    John G Hanly
    Division of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada B3H 4K4
    Best Pract Res Clin Rheumatol 19:799-821. 2005
    ..In the absence of controlled studies, the use of symptomatic therapies, immunosuppressives, anticoagulants and non-pharmacologic interventions is supported by case series and clinical experience...
  15. doi request reprint Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosus
    J G Hanly
    Department of Medicine, Division of Rheumatology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Rheum Dis 70:1726-32. 2011
    ..This study examined a disease inception cohort of 1047 SLE patients to determine which autoantibodies at enrolment predicted subsequent neuropsychiatric events...
  16. pmc SF-36 summary and subscale scores are reliable outcomes of neuropsychiatric events in systemic lupus erythematosus
    J G Hanly
    Division of Rheumatology, Nova Scotia Rehabilitation Centre 2nd floor, 1341 Summer Street, Halifax, NS B3H 4K4, Canada
    Ann Rheum Dis 70:961-7. 2011
    ..To examine change in health-related quality of life in association with clinical outcomes of neuropsychiatric events in systemic lupus erythematosus (SLE)...
  17. pmc Antiphospholipid syndrome: an overview
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS
    CMAJ 168:1675-82. 2003
    ..The mainstay of therapy is anticoagulation, whereas immunosuppression is ineffective...
  18. doi request reprint Comparison between multiplex assays for autoantibody detection in systemic lupus erythematosus
    John G Hanly
    Division of Rheumatology, Capital Health and Dalhousie University, Halifax, Nova Scotia, Canada
    J Immunol Methods 358:75-80. 2010
    ..Furthermore, there were differences between assays in their associations with global SLE disease activity and lupus nephritis...
  19. doi request reprint Assessment of cognitive function in systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis by computerized neuropsychological tests
    John G Hanly
    Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 62:1478-86. 2010
    ..This study was undertaken to compare patients with SLE, patients with rheumatoid arthritis (RA), and patients with multiple sclerosis (MS) with healthy controls using the Automated Neuropsychological Assessment Metrics (ANAM)...
  20. ncbi request reprint Neuropsychiatric events in systemic lupus erythematosus: attribution and clinical significance
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 31:2156-62. 2004
    ....
  21. ncbi request reprint ACR classification criteria for systemic lupus erythematosus: limitations and revisions to neuropsychiatric variables
    J G Hanly
    Department of Medicine, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada, B3H 4K4
    Lupus 13:861-4. 2004
    ....
  22. ncbi request reprint Neuropsychiatric lupus
    John G Hanly
    Division of Rheumatology, Arthritis Center of Nova Scotia, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS B3H 4K4, Canada
    Rheum Dis Clin North Am 31:273-98, vi. 2005
    ..Treatment remains largely empiric in the absence of controlled studies, and current strategies include the use of immunosuppressive therapies, appropriate symptomatic interventions, and the treatment of non-SLE factors...
  23. ncbi request reprint Neuropsychiatric syndromes in patients with systemic lupus erythematosus and rheumatoid arthritis
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 32:1459-6. 2005
    ..We compared the prevalence, diversity, and clinical significance of NP syndromes in patients with SLE and rheumatoid arthritis (RA)...
  24. doi request reprint Gout in the elderly--a population health study
    John G Hanly
    Division of Rheumatology, Department of Medicine, Queen Elizabeth II Health Sciences Centre, College of Pharmacy, Dalhousie University, Halifax, Nova Scotia B3H 4K4, Canada
    J Rheumatol 36:822-30. 2009
    ..To determine the incidence, healthcare utilization, and costs in older adults with gout...
  25. doi request reprint Headache in systemic lupus erythematosus: results from a prospective, international inception cohort study
    John G Hanly
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Arthritis Rheum 65:2887-97. 2013
    ..To examine the frequency and characteristics of headaches and their association with global disease activity and health-related quality of life (HRQOL) in patients with systemic lupus erythematosus (SLE)...
  26. doi request reprint Impact of a rheumatology consultation service on the diagnostic accuracy and management of gout in hospitalized patients
    Claire Barber
    Division of Rheumatology, Nova Scotia Rehabilitation Centre, Halifax, Nova Scotia
    J Rheumatol 36:1699-704. 2009
    ..To determine if a hospital rheumatology consultation service improves diagnostic accuracy and adherence to treatment recommendations for gout...
  27. ncbi request reprint Inhibition of annexin V binding to cardiolipin and thrombin generation in an unselected population with venous thrombosis
    John G Hanly
    Divisions of Rheumatology and Hematology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, 1341 Summer Street, Halifax, Nova Scotia, Canada B3H 4K4
    J Rheumatol 30:1990-3. 2003
    ..The prevalence of autoimmune antiphospholipid antibodies (aPL) was also determined...
  28. doi request reprint The accuracy of administrative data diagnoses of systemic autoimmune rheumatic diseases
    Sasha Bernatsky
    Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre MUHC, Montreal, Quebec, Canada
    J Rheumatol 38:1612-6. 2011
    ....
  29. ncbi request reprint Physician resources and postgraduate training in canadian academic rheumatology centers: a 5-year prospective study
    John G Hanly
    Canadian Council of Academic Rheumatologists and Dalhousie University, Halifax, Canada
    J Rheumatol 31:1200-5. 2004
    ..To describe the trends in physician resources, changes in activity profiles, and the output of the postgraduate training programs in Canadian academic rheumatology centers from 1998-2002...
  30. doi request reprint Cocaine-related retiform purpura: evidence to incriminate the adulterant, levamisole
    Noreen M G Walsh
    Department of Pathology, Capital District Health Authority and Dalhousie University, 5788 University Avenue, Halifax, Nova Scotia, Canada
    J Cutan Pathol 37:1212-9. 2010
    ..Urine toxicology shortly after a binge of cocaine use in each case was positive for levamisole...
  31. ncbi request reprint Meningeal involvement in Wegener's granulomatosis
    Ali Al Dhanhani
    Division of Rheumatology, Department of Medicine, the Division of Anatomical Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 33:364-7. 2006
    ..This rare neurological manifestation of WG was treated successfully with oral cyclophosphamide and the patient has continued remission for 3 years taking oral methotrexate...
  32. ncbi request reprint Factor V Leiden, prothrombin gene mutation, and thrombosis risk in patients with antiphospholipid antibodies
    Nikhil Chopra
    Division of Rheumatology, Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 29:1683-8. 2002
    ....
  33. ncbi request reprint Neuropsychiatric lupus
    J G Hanly
    Division of Rheumatology, Queen Elizabeth II Health Sciences Center, 310 Bethune Building, Halifax, Nova Scotia, B3H 2Y9, Canada
    Curr Rheumatol Rep 3:205-12. 2001
    ..Multicenter initiatives are required to address important issues on prognosis and management...
  34. ncbi request reprint Anti-beta2-glycoprotein I autoantibodies, in vitro thrombin generation, and the antiphospholipid syndrome
    J G Hanly
    Department of Medicine, Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 27:2152-9. 2000
    ....
  35. ncbi request reprint Efficacy of sacroiliac corticosteroid injections in patients with inflammatory spondyloarthropathy: results of a 6 month controlled study
    J G Hanly
    Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    J Rheumatol 27:719-22. 2000
    ..To evaluate changes in articular symptoms, spinal mobility, and global function over 6 months after intraarticular injections of long acting corticosteroid into the sacroiliac (SI) joints of patients with inflammatory low back pain (ILBP)...
  36. ncbi request reprint Association of autoantibodies to nuclear lamin B1 with thromboprotection in systemic lupus erythematosus: lack of evidence for a direct role of lamin B1 in apoptotic blebs
    Mélanie Dieudé
    Autoimmunity Research Laboratory, Notre Dame Hospital, Centre Hospitalier de l Universite de Montreal, 1560 Sherbrooke Street East, Montreal, Quebec H2L 4M1, Canada
    Arthritis Rheum 46:2695-707. 2002
    ....
  37. doi request reprint Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal response
    Michelle Petri
    Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Arthritis Rheum 58:1789-95. 2008
    ..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis...
  38. doi request reprint Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response index
    Michelle Petri
    Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Arthritis Rheum 58:1784-8. 2008
    ..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index...