C V Fernandez

Summary

Affiliation: Nova Scotia
Country: Canada

Publications

  1. doi request reprint Attitudes of Canadian researchers toward the return to participants of incidental and targeted genomic findings obtained in a pediatric research setting
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Genet Med 15:558-64. 2013
  2. pmc Recommendations for the return of research results to study participants and guardians: a report from the Children's Oncology Group
    Conrad V Fernandez
    Izaak Walton Killam and Steven Joffe Health Centre, Dalhousie University, Halifax, Nova Scotia
    J Clin Oncol 30:4573-9. 2012
  3. pmc The publication of ethically uncertain research: attitudes and practices of journal editors
    Carla Angelski
    Division of Pediatric Emergency Medicine, University of Alberta, Edmonton, AB, Canada
    BMC Med Ethics 13:4. 2012
  4. pmc Barriers to the enrollment of children in the Children's Oncology Group study of very low risk Wilms tumor: a report from the Children's Oncology Group
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia
    J Pediatr Hematol Oncol 33:521-3. 2011
  5. pmc Providing research results to participants: attitudes and needs of adolescents and parents of children with cancer
    Conrad Vincent Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, 5850 University Ave, PO Box 9700, Halifax, Nova Scotia, B3K 6R8, Canada
    J Clin Oncol 27:878-83. 2009
  6. pmc Anthropomorphic measurements and event-free survival in patients with favorable histology Wilms tumor: a report from the Children's Oncology Group
    Conrad V Fernandez
    IWK Health Centre, Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 52:254-8. 2009
  7. ncbi request reprint Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor
    C V Fernandez
    Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer Genet Cytogenet 129:165-7. 2001
  8. ncbi request reprint The return of research results to participants: pilot questionnaire of adolescents and parents of children with cancer
    C V Fernandez
    Department of Pediatrics, IWK Health Centre, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 48:441-6. 2007
  9. pmc Considerations and costs of disclosing study findings to research participants
    Conrad V Fernandez
    Division of Pediatric Hematology and Oncology, Department of Pediatrics, IWK Health Centre Halifax, Nova Scotia
    CMAJ 170:1417-9. 2004
  10. pmc Knowledge and attitudes of pregnant women with regard to collection, testing and banking of cord blood stem cells
    Conrad V Fernandez
    Department of Pediatrics, Dalhousie University, Halifax, NS
    CMAJ 168:695-8. 2003

Detail Information

Publications34

  1. doi request reprint Attitudes of Canadian researchers toward the return to participants of incidental and targeted genomic findings obtained in a pediatric research setting
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    Genet Med 15:558-64. 2013
    ..The purpose of this study was to explore the attitudes of genomics researchers in a pediatric setting in the context of regulatory guidance recommending the disclosure of clinically significant research findings...
  2. pmc Recommendations for the return of research results to study participants and guardians: a report from the Children's Oncology Group
    Conrad V Fernandez
    Izaak Walton Killam and Steven Joffe Health Centre, Dalhousie University, Halifax, Nova Scotia
    J Clin Oncol 30:4573-9. 2012
    ..The mechanism by which to do so in a cooperative research group setting has not been previously described...
  3. pmc The publication of ethically uncertain research: attitudes and practices of journal editors
    Carla Angelski
    Division of Pediatric Emergency Medicine, University of Alberta, Edmonton, AB, Canada
    BMC Med Ethics 13:4. 2012
    ..Our objective was to survey journal editors regarding practices and attitudes surrounding such dilemmas...
  4. pmc Barriers to the enrollment of children in the Children's Oncology Group study of very low risk Wilms tumor: a report from the Children's Oncology Group
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia
    J Pediatr Hematol Oncol 33:521-3. 2011
    ..We point out the necessity of assessing these concerns in predicting feasibility of and accrual to a therapy reduction study...
  5. pmc Providing research results to participants: attitudes and needs of adolescents and parents of children with cancer
    Conrad Vincent Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, 5850 University Ave, PO Box 9700, Halifax, Nova Scotia, B3K 6R8, Canada
    J Clin Oncol 27:878-83. 2009
    ..There is an increasing demand for researchers to provide research results to participants. Our aim was to define an appropriate process for this, based on needs and attitudes of participants...
  6. pmc Anthropomorphic measurements and event-free survival in patients with favorable histology Wilms tumor: a report from the Children's Oncology Group
    Conrad V Fernandez
    IWK Health Centre, Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 52:254-8. 2009
    ..We retrospectively examined the effect of body weight and body mass index (BMI) on event-free survival (EFS) of children with Wilms tumor treated on National Wilms Tumor Study-5 (NWTS-5)...
  7. ncbi request reprint Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor
    C V Fernandez
    Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer Genet Cytogenet 129:165-7. 2001
    ..This was confirmed using fluorescence in situ hybridization analysis. Molecular analysis of this rearrangement may provide clues to understanding the pathobiology of Wilms tumor...
  8. ncbi request reprint The return of research results to participants: pilot questionnaire of adolescents and parents of children with cancer
    C V Fernandez
    Department of Pediatrics, IWK Health Centre, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 48:441-6. 2007
    ..We examined the needs and attitudes of parents of children with cancer and of adolescents with cancer to the return of research results...
  9. pmc Considerations and costs of disclosing study findings to research participants
    Conrad V Fernandez
    Division of Pediatric Hematology and Oncology, Department of Pediatrics, IWK Health Centre Halifax, Nova Scotia
    CMAJ 170:1417-9. 2004
  10. pmc Knowledge and attitudes of pregnant women with regard to collection, testing and banking of cord blood stem cells
    Conrad V Fernandez
    Department of Pediatrics, Dalhousie University, Halifax, NS
    CMAJ 168:695-8. 2003
    ..We sought to examine pregnant women's knowledge and attitudes regarding cord blood banking, as their support is crucial to the success of cord blood transplant programs...
  11. ncbi request reprint Disclosure of the right of research participants to receive research results: an analysis of consent forms in the Children's Oncology Group
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer 97:2904-9. 2003
    ..The current study examined the offer of return of research results by analyzing consent forms from 2 acute lymphoblastic leukemia studies of the 235 institutional members of the Children's Oncology Group...
  12. ncbi request reprint Offering to return results to research participants: attitudes and needs of principal investigators in the Children's Oncology Group
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    J Pediatr Hematol Oncol 25:704-8. 2003
    ..The authors determined current practice and attitudes and needs of researchers in establishing programs to return results to research participants...
  13. ncbi request reprint Strategies for the prevention of medical error in pediatrics
    Conrad V Fernandez
    Division of Pediatric Hematology Oncology, IWK Health Center, Dalhousie University Halifax, 5850 University Avenue, Halifax, Nova Scotia B3J 3G9, Canada
    J Pediatr 143:155-62. 2003
  14. pmc Informing research participants of research results: analysis of Canadian university based research ethics board policies
    S D MacNeil
    IWK Health Centre, PO Box 9700, 5850 5980 University Avenue, Halifax, Nova Scotia, B3K 6R8 Canada
    J Med Ethics 32:49-54. 2006
    ..The policies of Canadian research ethics boards (REBs) are unknown...
  15. doi request reprint JAK2 V617F positive polycythemia Vera in a child with neurofibromatosis type I
    Jason N Berman
    Dalhousie Cancer Genetics Research Group, Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 51:689-91. 2008
    ..Neurofibromin sequencing failed to identify a causative mutation. An unknown genetic abnormality resulting in NF1 may have predisposed this young child to acquiring the common JAK2 mutation...
  16. ncbi request reprint Informing study participants of research results: an ethical imperative
    Conrad V Fernandez
    Division of Pediatric Hematology Oncology, Department of Pediatrics, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    IRB 25:12-9. 2003
  17. ncbi request reprint Offering results to research subjects: U.S. Institutional Review Board policy
    Christa Kozanczyn
    School of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Account Res 14:255-67. 2007
    ..This study aims to determine the nature of United States Institutional Review Board (IRB) policy in a broad spectrum of research settings regarding the return of results to study participants...
  18. ncbi request reprint Offering parents individualized feedback on the results of psychological testing conducted for research purposes with children: ethical issues and recommendations
    Marie josée Lefaivre
    Department of Psychology, Dalhousie University, Halifax, NS, Canada
    J Clin Child Adolesc Psychol 36:242-52. 2007
    ..Two hypothetical cases are offered to illustrate the complexities of this topic. Detailed recommendations for the management of disclosure of the results of psychological testing in research settings are also proposed...
  19. ncbi request reprint Obligations in offering to disclose genetic research results
    Conrad V Fernandez
    Dalhousie University, Canada
    Am J Bioeth 6:44-6; author reply W10-2. 2006
  20. doi request reprint The use of ultrasound in endemic Burkitt lymphoma in Cameroon
    S Marjerrison
    Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 58:352-5. 2012
    ..This retrospective chart review was designed to assess: (1) abdominal US utilisation, (2) the incidence of abdominal disease at diagnosis, (3) correlation of extent of disease at diagnosis with overall and event-free survival (EFS)...
  21. doi request reprint Failure to report and provide commentary on research ethics board approval and informed consent in medical journals
    K A Finlay
    Dalhousie University, Halifax, Nova Scotia, Canada
    J Med Ethics 34:761-4. 2008
    ..Despite this prohibition and a call to highlight the deficiency for the reader, articles with potential ethical shortcomings continue to be published...
  22. doi request reprint The impact of prophylactic fresh-frozen plasma and cryoprecipitate on the incidence of central nervous system thrombosis and hemorrhage in children with acute lymphoblastic leukemia receiving asparaginase
    Lesleigh S Abbott
    Department of Pediatrics, Dalhousie University and Isaak Walton Killam Health Centre, Halifax, NS, Canada
    Blood 114:5146-51. 2009
    ..Neither FFP nor CRY protected against CNST, suggesting prophylaxis is unwarranted for unselected ALL patients. However, prophylactic replacement for HR patients in induction may be cost-effective...
  23. doi request reprint Allogeneic hematopoietic stem cell transplantation of patients with FA and high risk features using fludarabine without radiation
    Jillian M Baker
    Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatr Blood Cancer 52:683-5. 2009
    ..This fludarabine based regimen without radiation was safe and effective for four high-risk patients, suggesting that eliminating radiation should be further studied as an approach to HSCT in children with FA...
  24. ncbi request reprint Providing research results to study participants: support versus practice of researchers presenting at the American Society of Hematology annual meeting
    Heather Rigby
    School of Medicine, Dalhousie University, Halifax, NS, Canada
    Blood 106:1199-202. 2005
    ..Given the high level of support in the international research community, evaluation of well-planned interventions for offering to provide research results to participants should be a priority...
  25. pmc Attitudes of research ethics board chairs towards disclosure of research results to participants: results of a national survey
    S Danielle MacNeil
    Department of Surgery, Division of Otolaryngology, University of British Columbia, Vancouver, British Columbia, Canada
    J Med Ethics 33:549-53. 2007
    ..The attitudes of research ethics board (REB) chairs towards this practice, although integral to policy development, are unknown...
  26. ncbi request reprint Publication of ethically suspect research: should it occur?
    Conrad V Fernandez
    Int J Qual Health Care 17:377-8. 2005
  27. ncbi request reprint Importance of informed consent in offering to return research results to research participants
    Conrad V Fernandez
    Med Pediatr Oncol 41:592-3. 2003
  28. doi request reprint Routine bone marrow examination in the initial evaluation of paediatric Hodgkin lymphoma: the Canadian perspective
    C David Simpson
    Department of Paediatrics, Dalhousie University, and IWK Health Centre, Halifax, NS, Canada
    Br J Haematol 141:820-6. 2008
    ..Comparison of staging with and without BME demonstrated no significant difference to final risk classification. BME in paediatric patients with low-stage HL has extremely low yield and may be unnecessary...
  29. ncbi request reprint Psychosocial needs of families with a child with cancer
    Gustaf Ljungman
    Department of Women s and Children s Health, Uppsala University, Unit of Pediatric Hematology and Oncology, University Children s Hospital, Uppsala, Sweden
    J Pediatr Hematol Oncol 25:223-31. 2003
    ..The aims of this study were to map the problems and needs of children with cancer and their families with regard to possible psychosocial interventions, and to do an acceptability study of different ways to provide support...
  30. pmc Offering results to research participants
    S Danielle MacNeil
    BMJ 332:188-9. 2006
  31. ncbi request reprint Providing research participants with findings from completed cancer-related clinical trials: not quite as simple as it sounds
    Conrad V Fernandez
    Cancer 107:1419-20; author reply 1420. 2006
  32. ncbi request reprint Validity and consequence of informed consent in pediatric bone marrow transplantation: The parental experience
    Jan M Benedict
    Department of Family Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 49:846-51. 2007
    ..We studied if parents perceived choice when consenting to BMT, if they felt the consent provided was valid, and how the consent process affected them...
  33. pmc Our moral obligations in caring for patients with orphan cancers
    Conrad V Fernandez
    CMAJ 176:297, 299. 2007
  34. ncbi request reprint Involving children with cancer in decision-making about research participation
    Steven Joffe
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Pediatr 149:862-868. 2006