Evgeny Vinogradov

Summary

Affiliation: National Research Council
Country: Canada

Publications

  1. ncbi The structure of the carbohydrate backbone of the LPS from Shewanella spp. MR-4
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 343:2701-5. 2008
  2. ncbi A reinvestigation of the lipopolysaccharide structure of Helicobacter pylori strain Sydney (SS1)
    Eleonora Altman
    Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada
    FEBS J 278:3484-93. 2011
  3. ncbi The structure of the carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-79104
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa ON, Canada K1A 0R6
    Carbohydr Res 339:1637-42. 2004
  4. ncbi The structure of the core region of the lipopolysaccharide from Shewanella algae BrY, containing 8-amino-3,8-dideoxy-D-manno-oct-2-ulosonic acid
    Evgeny Vinogradov
    Institute for Biological Sciences, NRC, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:737-40. 2004
  5. ncbi The structure of the rough-type lipopolysaccharide from Shewanella oneidensis MR-1, containing 8-amino-8-deoxy-Kdo and an open-chain form of 2-acetamido-2-deoxy-D-galactose
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa ON K1A 0R6 Canada
    Carbohydr Res 338:1991-7. 2003
  6. ncbi Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada
    Eur J Biochem 270:3036-46. 2003
  7. ncbi The structure of the glucuronoxylomannan produced by culinary-medicinal yellow brain mushroom (Tremella mesenterica Ritz.:Fr., Heterobasidiomycetes) grown as one cell biomass in submerged culture
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:1483-9. 2004
  8. ncbi The structure of the polysaccharide part of the LPS from Serratia marcescens serotype O19, including linkage region to the core and the residue at the non-reducing end
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 338:2757-61. 2003
  9. ncbi Characterisation of the core part of the lipopolysaccharide O-antigen of Francisella novicida (U112)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 339:1643-8. 2004
  10. ncbi The structure of the O-specific polysaccharide from Ralstonia pickettii
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:2045-7. 2004

Detail Information

Publications87

  1. ncbi The structure of the carbohydrate backbone of the LPS from Shewanella spp. MR-4
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 343:2701-5. 2008
    ..Two structural variants have been found, both contained 8-amino-3,8-dideoxy-d-manno-octulosonic acid and lacked L-glycero-D-manno-heptose. A minor variant of the LPS contained phosphoramide substituent...
  2. ncbi A reinvestigation of the lipopolysaccharide structure of Helicobacter pylori strain Sydney (SS1)
    Eleonora Altman
    Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada
    FEBS J 278:3484-93. 2011
    ..pylori SS1 LPS was found to contain a novel LacNAc unit carrying a phosphoethanolamine substituent at the O-6 position of β-GlcNAc residues...
  3. ncbi The structure of the carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-79104
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa ON, Canada K1A 0R6
    Carbohydr Res 339:1637-42. 2004
    ..This structure is architecturally similar to the oligosaccharide system reported previously in P. frisingensis VTT E-82164 LPS, but differs from the latter in composition and also in the size of the outer region...
  4. ncbi The structure of the core region of the lipopolysaccharide from Shewanella algae BrY, containing 8-amino-3,8-dideoxy-D-manno-oct-2-ulosonic acid
    Evgeny Vinogradov
    Institute for Biological Sciences, NRC, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:737-40. 2004
    ..This LPS presents a second example (after S. oneidensis) of the structure with a novel linking unit between the core and lipid A moieties, 8-amino-3,8-dideoxy-D-manno-oct-2-ulosonic acid (8-amino-Kdo)...
  5. ncbi The structure of the rough-type lipopolysaccharide from Shewanella oneidensis MR-1, containing 8-amino-8-deoxy-Kdo and an open-chain form of 2-acetamido-2-deoxy-D-galactose
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa ON K1A 0R6 Canada
    Carbohydr Res 338:1991-7. 2003
    ..The structure contains a phosphodiester linkage between the alpha-D-galactopyranose and D-glycero-D-manno-heptose (DDHep) residues...
  6. ncbi Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada
    Eur J Biochem 270:3036-46. 2003
    ..Analysis of the deacylation products obtained from the LPS of the smooth strain, VTT E-79100T, showed that it contains a very similar core but with one different glycosidic linkage...
  7. ncbi The structure of the glucuronoxylomannan produced by culinary-medicinal yellow brain mushroom (Tremella mesenterica Ritz.:Fr., Heterobasidiomycetes) grown as one cell biomass in submerged culture
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:1483-9. 2004
    ..These results differ from previously published structure of Tremella extracellular polysaccharides, where mannan backbone was believed to be randomly glycosylated with xylan chains of different length...
  8. ncbi The structure of the polysaccharide part of the LPS from Serratia marcescens serotype O19, including linkage region to the core and the residue at the non-reducing end
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 338:2757-61. 2003
    ..The polysaccharide has a beta-Kdo residue at the non-reducing end, a feature similar to that observed previously in the LPS from Klebsiella O12...
  9. ncbi Characterisation of the core part of the lipopolysaccharide O-antigen of Francisella novicida (U112)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 339:1643-8. 2004
    ..The lipid part of F. novicida LPS contains no phosphate substituent and apparently has a free reducing end, a feature also noted in F. tularensis LPS...
  10. ncbi The structure of the O-specific polysaccharide from Ralstonia pickettii
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:2045-7. 2004
    ..The following structure of the Ralstonia pickettii have been determined using NMR and chemical methods: -->4)-alpha-D-Rha-(1-->4)-alpha-L-GalNAcA-(1-->3)-beta-D-BacNAc-(1-->...
  11. ncbi The structure of the O-specific polysaccharide from Salmonella cerro (serogroup K, O:6,14,18)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:2441-3. 2004
    ..The following structure of the Salmonella cerro LPS O-chain repeating unit has been determined using NMR and chemical methods: -->4)-alpha-D-Man(1-->2)-alpha-D-Man(1-->2)-beta-D-Man(1-->3)-alpha-D-GalNAc-(1-->...
  12. ncbi The structure of the core region of the lipopolysaccharide from Geobacter sulfurreducens
    Evgeny Vinogradov
    Institute for Biological Sciences, NRC, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 339:2901-4. 2004
    ..It was studied by chemical methods, NMR and mass spectrometry, and the following structure was proposed. [carbohydrate structure: see text] where Q = 3-O-Me-alpha-L-QuiNAc-(1-->or H (approximately 3:2)...
  13. ncbi The structure and biological characteristics of the Spirochaeta aurantia outer membrane glycolipid LGLB
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada
    Eur J Biochem 271:4685-95. 2004
    ....
  14. ncbi Structure of the O-antigen polysaccharide present in the lipopolysaccharide of Cronobacter dublinensis (subspecies lactaridi or lausannensis) HPB 3169
    Leann L MacLean
    Institute for Biological Sciences, National Research Council, Ottawa, ON K1A 0R6, Canada
    Can J Microbiol 58:540-6. 2012
    ..sakazakii HPB 3169 strain O-antigen...
  15. ncbi The structure of the exocellular polysaccharide produced by Rhodococcus sp. RHA1
    Malcolm B Perry
    Institute for Biological Sciences, National Research Council, Ottawa, Canada K1A 0R6
    Carbohydr Res 342:2223-9. 2007
    ..The EPS was found to be a high-molecular-mass polymer of a repeating tetrasaccharide unit composed of D-glucuronic acid, D-glucose, D-galactose, L-fucose and O-acetyl (1:1:1:1:1), and has the structure:..
  16. ncbi The HS:19 serostrain of Campylobacter jejuni has a hyaluronic acid-type capsular polysaccharide with a nonstoichiometric sorbose branch and O-methyl phosphoramidate group
    David J McNally
    Institute for Biological Sciences, National Research Council of Canada, Ottawa Ontario, Canada
    FEBS J 273:3975-89. 2006
    ..The findings of this work with the HS:19 serostrain now present a means to explore the role of CPS as a virulence factor in C. jejuni...
  17. ncbi Characterization of the lipopolysaccharide O-antigen of Cronobacter turicensis HPB3287 as a polysaccharide containing a 5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid (legionaminic acid) residue
    Leann L MacLean
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 346:2589-94. 2011
    ....
  18. ncbi The structure of the polysaccharide of the lipopolysaccharide produced by Taylorella equigenitalis type strain (ATCC 35865)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada
    Carbohydr Res 343:3079-84. 2008
    ..asinigenitalis sp. nov, a phenotypically indistinguishable non-pathogenic bacterium having a serologically and structurally unrelated LPS O-antigen. The analysis of a structurally unusual core oligosaccharide of the LPS is also reported...
  19. ncbi Structural and genetic basis for the serological differentiation of Pasteurella multocida Heddleston serotypes 2 and 5
    Frank St Michael
    Institute for Biological Sciences, 100 Sussex Drive, National Research Council, Ottawa, Ontario K1A 0R6, Canada
    J Bacteriol 191:6950-9. 2009
    ..These data indicate that the serological classification of strains into Heddleston serotypes 2 and 5 is dependent on the presence or absence of PEtn on Hep II...
  20. ncbi The application of NMR spectroscopy to functional glycomics
    Jean Robert Brisson
    Institute for Biological Sciences, National Research Council Canada, Ottawa, Ontario, Canada
    Methods Mol Biol 600:155-73. 2010
    ....
  21. ncbi The HS:1 serostrain of Campylobacter jejuni has a complex teichoic acid-like capsular polysaccharide with nonstoichiometric fructofuranose branches and O-methyl phosphoramidate groups
    David J McNally
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    FEBS J 272:4407-22. 2005
    ..jejuni HS:1 as a strategy to produce a highly complex polysaccharide from its small CPS biosynthetic locus and a limited number of sugars...
  22. ncbi Structural studies of the core region of Aeromonas salmonicida subsp. salmonicida lipopolysaccharide
    Zhan Wang
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 341:109-17. 2006
    ..salmonicida subsp. salmonicida core oligosaccharides from strains A449, 80204-1 and an in vivo rough isolate confirmed that the structure of the core oligosaccharide was conserved among different isolates of A. salmonicida...
  23. ncbi Flagellar glycosylation in Clostridium botulinum
    Susan M Twine
    NRC Institute for Biological Sciences, Ottawa, Canada
    FEBS J 275:4428-44. 2008
    ..botulinum cells, indicating botulinum neurotoxin contamination. This is the first report of glycosylation of Gram-positive flagellar proteins by the 'sialic acid-like' nonulosonate sugar, legionaminic acid...
  24. ncbi Structural characterization of the antigenic capsular polysaccharide and lipopolysaccharide O-chain produced by Actinobacillus pleuropneumoniae serotype 15
    Malcolm B Perry
    Institute for Biological Science, National Research Council Canada, Ottawa, ON K1A 0R6, Canada
    Biochem Cell Biol 83:61-9. 2005
    ..The O-PS was chemically identical with the O-antigen previously identified in the LPSs produced by A. pleuro pneumoniae serotypes 3 and 8...
  25. ncbi Lipooligosaccharide of Campylobacter jejuni: similarity with multiple types of mammalian glycans beyond gangliosides
    R Scott Houliston
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A 0R6, Canada
    J Biol Chem 286:12361-70. 2011
    ..We show that the sialyltransferase CstII and the galactosyltransferase CgtD are involved in the synthesis of multiple mimic types, with LOS structural diversity achieved through evolving allelic substrate specificity...
  26. ncbi Identification and differentiation of Taylorella equigenitalis and Taylorella asinigenitalis by lipopolysaccharide O-antigen serology using monoclonal antibodies
    Brian W Brooks
    Canadian Food Inspection Agency, Ottawa Laboratory Fallowfield, Ottawa, Ontario
    Can J Vet Res 74:18-24. 2010
    ..Lipopolysaccharide O-PS could be a specific marker for identification and differentiation of T. equigenitalis and T. asinigenitalis, and provide the basis for the development of specific detection assays for T. equigenitalis...
  27. ncbi Characterization of the O-antigen in the lipopolysaccharide of Cronobacter (Enterobacter) malonaticus 3267
    Leann L MacLean
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON K1A 0R6, Canada
    Biochem Cell Biol 87:927-32. 2009
    ....
  28. ncbi Identification of novel carbohydrate modifications on Campylobacter jejuni 11168 flagellin using metabolomics-based approaches
    Susan M Logan
    NRC Institute for Biological Sciences, Ottawa, Canada
    FEBS J 276:1014-23. 2009
    ..This is the first comprehensive analysis of the flagellar modifications in C. jejuni 11168 and structural elucidation of di-O-methylglyceric acid derivatives of pseudaminic acid on Campylobacter flagellin...
  29. ncbi The structure of the polysaccharide O-chain of the LPS from Acinetobacter baumannii strain ATCC 17961
    Leann L MacLean
    Institute for Biological Sciences, National Research Council Canada, ON, Canada
    Carbohydr Res 344:474-8. 2009
    ....
  30. ncbi Identification of labile UDP-ketosugars in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa: key metabolites used to make glycan virulence factors
    David J McNally
    National Research Council of Canada-Institute for Biological Sciences, Ottawa ON, K1A 0R6, Canada
    Chembiochem 7:1865-8. 2006
  31. ncbi Structural and serological characterization of the O-chain polysaccharide of Aeromonas salmonicida strains A449, 80204 and 80204-1
    Zhan Wang
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 340:693-700. 2005
    ....
  32. ncbi Phosphoethanolamine is located at the 6-position and not at the 7-position of the distal heptose residue in the lipopolysaccharide from Neisseria meningitidis
    Frank St Michael
    Institute for Biological Sciences, National Research Council, Ottawa, ON, K1A 0R6, Canada
    Glycobiology 19:1436-45. 2009
    ..We discuss the implications of these findings with respect to the immunotyping scheme for the meningococci and in the context of LPS-based vaccine development...
  33. ncbi Structural studies of the capsular polysaccharide and lipopolysaccharide O-antigen of Aeromonas salmonicida strain 80204-1 produced under in vitro and in vivo growth conditions
    Zhan Wang
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Canada
    Eur J Biochem 271:4507-16. 2004
    ....
  34. ncbi The structure of the O-specific polysaccharide chain of the Shewanella algae BrY lipopolysaccharide
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, ON, K1A 0R6, Ottawa, Canada
    Carbohydr Res 338:385-8. 2003
    ..The repeating unit includes linkage via the residue of malic acid, reported here for the first time as a component of bacterial polysaccharides...
  35. ncbi Lipopolysaccharides from Serratia marcescens possess one or two 4-amino-4-deoxy-L-arabinopyranose 1-phosphate residues in the lipid A and D-glycero-D-talo-oct-2-ulopyranosonic acid in the inner core region
    Evgeny Vinogradov
    Institute for Biological Sciences, NRC Canada, Ottawa, ON K1 A 0R6, Canada
    Chemistry 12:6692-700. 2006
    ..We also identified some truncated structures for both strains. All sugars were D-configured pyranoses and alpha-linked, except where stated otherwise...
  36. ncbi Structural analysis of the lipopolysaccharide of Pasteurella multocida strain VP161: identification of both Kdo-P and Kdo-Kdo species in the lipopolysaccharide
    Frank St Michael
    Institute for Biological Sciences, National Research Council, Ottawa, ON, K1A 0R6, Canada
    Carbohydr Res 340:59-68. 2005
    ..This variation in the Kdo region of the LPS was also observed in several other Pasteurella multocida strains investigated including the genome strain Pm70...
  37. ncbi Lipopolysaccharide structures of Helicobacter pylori wild-type strain 26695 and 26695 HP0826::Kan mutant devoid of the O-chain polysaccharide component
    Eleonora Altman
    Institute for Biological Sciences, National Research Council Canada, Ottawa, Canada
    Carbohydr Res 346:2437-44. 2011
    ..This structure differs from previously reported structures of the H. pylori 26695 LPS in several aspects...
  38. ncbi Structural analysis of the capsular polysaccharide from Campylobacter jejuni RM1221
    Michel Gilbert
    Institute for Biological Sciences, National Research Council Canada, 100 Sussex Drive, Ottawa, K1A 0R6, Canada
    Chembiochem 8:625-31. 2007
    ..We have also shown that the CPS biosynthesis genes of C. jejuni RM1221 are conserved in other C. jejuni strains of the Penner serotype HS:53, including serotype HS:53 reference strain RM3435...
  39. ncbi The structure of the carbohydrate backbone of the LPS from Shewanella putrefaciens CN32
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ont, Canada
    Carbohydr Res 337:1285-9. 2002
    ..spectroscopy and chemical methods, and the following structure of its carbohydrate backbone is proposed: beta-Galf-(1-->3)-beta-Gal-(1-->4)-beta-Glc-(1-->4)-alpha-DDHep2PEtN-(1-->5)-alpha-Kdo4P-(1-->6)-beta-GlcN4P-(1-->6)-alpha-GlcN1P..
  40. ncbi A novel N-linked flagellar glycan from Methanococcus maripaludis
    John Kelly
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 344:648-53. 2009
    ..This oligosaccharide has significant similarity to the oligosaccharide that was found previously in Methanococcus voltae...
  41. ncbi Structure of the polysaccharide chain of the lipopolysaccharide from Flexibacter maritimus
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada
    Eur J Biochem 270:1810-5. 2003
    ..The LPS was also found to contain a minor amount of a disaccharide beta-Sug-(2-3)-l-Rha, isolated from the products of the acidic methanolysis of the LPS...
  42. ncbi The structural characterization of the O-polysaccharide antigen of the lipopolysaccharide of Escherichiacoli serotype O118 and its relation to the O-antigens of Escherichiacoli O151 and Salmonellaenterica O47
    Leann L MacLean
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 345:2664-9. 2010
    ..coli O151:H10 reference strain 880-67, as predicted from the results of DNA sequencing of their respective O-antigen gene-clusters...
  43. ncbi Effect of the HP0159 ORF mutation on the lipopolysaccharide structure and colonizing ability of Helicobacter pylori
    Eleonora Altman
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada
    FEMS Immunol Med Microbiol 53:204-13. 2008
    ..Colonization studies with HP0159 mutants of two mouse-colonizing strains, SS1 and M6, confirmed their inability to successfully colonize the murine stomach...
  44. ncbi The structure of the carbohydrate backbone of the rough type lipopolysaccharides from Proteus penneri strains 12, 13, 37 and 44
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Drive, Ottawa, Ont, Canada K1A 0R6
    Carbohydr Res 337:835-40. 2002
    ..The phosphate group at O-1 of the alpha-GlcN residue in the lipid part was partially substituted with Ara4N...
  45. ncbi Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways
    Ian C Schoenhofen
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada
    J Biol Chem 281:723-32. 2006
    ....
  46. ncbi The structure of the O-antigen of Cronobacter sakazakii HPB 2855 isolate involved in a neonatal infection
    Leann L MacLean
    Institute for Biological Sciences, National Research Council, Ottawa, Canada
    Carbohydr Res 345:1932-7. 2010
    ..From composition and methylation analysis, and the application of 1D and 2D (1)H and (13)C NMR spectroscopy, the O-PS was determined to be a polymer of a repeating oligosaccharide unit having the structure:..
  47. ncbi The structure of the capsular polysaccharide of Shewanella oneidensis strain MR-4
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 340:1750-3. 2005
    ....
  48. ncbi Structures of lipopolysaccharides from Klebsiella pneumoniae. Eluicidation of the structure of the linkage region between core and polysaccharide O chain and identification of the residues at the non-reducing termini of the O chains
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A 0R6, Canada
    J Biol Chem 277:25070-81. 2002
    ..All serotypes had an identical linkage between the O chain and core...
  49. ncbi Structural characterization of the lipopolysaccharide O-antigen from atypical isolate of Vibrio anguillarum strain 1282
    Zhan Wang
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
    Carbohydr Res 344:1371-5. 2009
    ..In addition, it was demonstrated that some of 2,3-diamino-2,3-dideoxy-glucuronamide in the O-PS was present in the form of 2,3-diamino-2,3-dideoxy-glucose...
  50. ncbi The structure of the antigenic O-polysaccharide in the lipopolysaccharide of enterohaemorrhagic Escherichia coli serotype O71:H12
    Leann L MacLean
    Institute for Biological Sciences, National Research Council, Ottawa, ON K1A 0R6, Canada
    Biochem Cell Biol 88:439-44. 2010
    ..unbranched polymer of a repeating tetrasaccharide unit composed of L-rhamnose, D-galactose, 2-acetamido-2-deoxy-D-galactose, and 3-acetamido-3-deoxy-D-quinovose (1:1:1:1) residues having the following structure: [structure: see text]..
  51. ncbi Characterization of the lipopolysaccharides and capsules of Shewanella spp
    Anton A Korenevsky
    Department of Microbiology, College of Biological Science, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
    Appl Environ Microbiol 68:4653-7. 2002
    ..These same polymers in S. algae may also contribute to this opportunistic pathogen's ability to promote infection...
  52. ncbi The structure of the antigenic O-polysaccharide of the lipopolysaccharide of Edwardsiella ictaluri strain MT104
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada
    Carbohydr Res 340:1509-13. 2005
    ..The O-chain was found to be a linear polymer of a repeating tetrasaccharide unit composed of D-glucose, 2-acetamido-2-deoxy-D-galactose, and D-galactose in a 1:2:1 ratio having the structure: [carbohydrate structure]; see text...
  53. ncbi Structural determination of the O-antigenic polysaccharide of enteropathogenic Escherichia coli O103:H2
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Drive, Ottawa, ON K1A 0R6, Canada
    Can J Microbiol 56:366-72. 2010
    ....
  54. ncbi Structural analyses of the core oligosaccharide from the lipopolysaccharide of bovine and ovine strains of Mannheimia haemolytica serotype 2
    Frank St Michael
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 346:1333-6. 2011
    ..The structural analyses revealed that the conserved inner core structure was maintained in this serotype, with only the terminal β-galactose residue of serotype 1 absent...
  55. ncbi The structure of a polysaccharide isolated from Inonotus levis P. Karst. mushroom (Heterobasidiomycetes)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 340:2821-5. 2005
    ..Another polymer, co-extracted with this galactan, was a branched phosphorylated mannan with a structure similar to that of the mannan from Saccharomyces cerevisiae yeast...
  56. ncbi Structural characterization of the O-polysaccharide antigen of Edwardsiella tarda MT 108
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, ON, K1A OR6, Canada
    Carbohydr Res 340:85-90. 2005
    ....
  57. ncbi The structure of the core-O-chain linkage region of the lipopolysaccharide from Bordetella hinzii
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, Ont, Canada K1A 0R6
    Carbohydr Res 342:638-42. 2007
    ..Polysaccharide part (PS) consists of not more than 15 2,3-diacetamido-2,3-dideoxyhexuronamides, methylated at the only hydroxyl group of the non-reducing terminal monosaccharide...
  58. ncbi Glycosyltransferases involved in biosynthesis of the outer core region of Escherichia coli lipopolysaccharides exhibit broader substrate specificities than is predicted from lipopolysaccharide structures
    Michael D Leipold
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada
    J Biol Chem 282:26786-92. 2007
    ..These results illustrate the differences in behavior between closely related glycosyltransferase enzymes involved in the synthesis of similar glycoconjugates and have implications for glycoengineering applications...
  59. ncbi The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors
    Ian C Schoenhofen
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, K1A 0R6 Canada
    Glycobiology 19:715-25. 2009
    ....
  60. ncbi Antigenic Variation among Bordetella: Bordetella bronchiseptica strain MO149 expresses a novel o chain that is poorly immunogenic
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A 0R6, Canada
    J Biol Chem 285:26869-77. 2010
    ..We also determine experimentally, for the first time, the absolute configuration of the diacetimido-uronic acid sugars in Bordetella O PS...
  61. ncbi Detection of conserved N-linked glycans and phase-variable lipooligosaccharides and capsules from campylobacter cells by mass spectrometry and high resolution magic angle spinning NMR spectroscopy
    Christine M Szymanski
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada
    J Biol Chem 278:24509-20. 2003
    ....
  62. ncbi The structure of the glycopeptides from the fish pathogen Flavobacterium columnare
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 338:2653-8. 2003
    ..Only one carbohydrate structure was found. The peptide part was represented by tri- to hepta-peptides with a minimal common tripeptide fragment Asp-Ser-Ala, extended with Ala and Val...
  63. ncbi Characterization of the lipopolysaccharide O-antigen of Francisella novicida (U112)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada K1A OR6
    Carbohydr Res 339:649-54. 2004
    ..Thus, O-PS serology offers a practical way to distinguish between the two Francisella species...
  64. ncbi The structure of the carbohydrate backbone of the LPS from Myxococcus xanthus strain DK1622
    Leann Maclean
    Institute for Biological Sciences, National Research Council, 100 Sussex Dr, Ottawa, ON, Canada K1A 0R6
    Carbohydr Res 342:2474-80. 2007
    ..The lipid A component consisted of beta-GlcN-(1-->6)-alpha-GlcN1P disaccharide, N-acylated with 13-methyl-C14-3OH (iso-C15-3OH), C16-3OH, and 15-methyl-C16-3OH (iso-C17-3OH) acids. The lipid portion contained O-linked iso-C16 acid...
  65. ncbi Complete structures of Bordetella bronchiseptica and Bordetella parapertussis lipopolysaccharides
    Andrew Preston
    Institute for Biological Sciences, National Research Council, 100 Sussex Drive, Ottawa, Ontario K1A OR6, Canada
    J Biol Chem 281:18135-44. 2006
    ..These new data describe the complete structure of the LPS carbohydrate backbone for both Bordetella species and help to explain the complex genetics of LPS biosynthesis in these bacteria...
  66. ncbi Structure of the core part of the lipopolysaccharides from Proteus penneri strains 7, 8, 14, 15, and 21
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Drive, Ottawa, Ontario K1A 0R6, Canada
    Carbohydr Res 337:643-9. 2002
    ..While structural features of the inner core part are shared by Proteus strains studied earlier, the outermost Q-(1-->4)-alpha-GalNAc-(1-->2)-alpha-DDHep-(1-->6)-alpha-GlcN oligosaccharide unit has not been hitherto reported...
  67. ncbi Structural analysis of Francisella tularensis lipopolysaccharide
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, Ottawa, Canada
    Eur J Biochem 269:6112-8. 2002
    ..LPS of F. tularensis exhibits unusual biological properties, including low endoxicity, which may be related to its unusual lipid A structure...
  68. ncbi Structure of the O-specific polysaccharide chain of the lipopolysaccharide of Bordetella hinzii
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Drive, Ottawa, Ont, Canada K1A 0R6
    Carbohydr Res 337:961-3. 2002
    ..The polysaccharide chain is terminated with a 4-O-methylated GalNAc3NAcAN residue and is rather short (n < or = 5)...
  69. ncbi Structural analysis of the lipopolysaccharide from Pasteurella multocida genome strain Pm70 and identification of the putative lipopolysaccharide glycosyltransferases
    Frank St Michael
    Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada, K1A 0R6
    Glycobiology 15:323-33. 2005
    ..Identification of the core oligosaccharide structure enabled a search for glycosyltransferase homologs in the Pm70 genome and revealed a clustering of the genes putatively responsible for outer core oligosaccharide biosynthesis...
  70. ncbi Structure of the O-polysaccharide of the lipopolysaccharide produced by Taylorella asinigenitalis type strain (ATCC 700933)
    Evgeny Vinogradov
    Institute for Biological Sciences, National Research Council, 100 Sussex Drive, Ottawa, ON, Canada
    Biochem Cell Biol 86:278-84. 2008
    ..equigenitalis type strain, thus providing a cell-surface target macromolecule that can be used to distinguish pathogenic from nonpathogenic Taylorella sp. clinical isolates...
  71. ncbi Structure of a novel lipid A obtained from the lipopolysaccharide of Caulobacter crescentus
    John Smit
    Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada
    Innate Immun 14:25-37. 2008
    ..This and other evidence suggests the potential application of this lipid A as a vaccine adjuvant or the suitability of Caulobacter displaying antigens for formulation of whole cell vaccines...
  72. ncbi The role of galacturonic acid in outer membrane stability in Klebsiella pneumoniae
    Emilisa Frirdich
    Department of Molecular and Cellular Biology, University of Guelph, Guelph Ontario N1G 2W1, Canada
    J Biol Chem 280:27604-12. 2005
    ..coli and Salmonella...
  73. ncbi Investigation of the structural requirements in the lipopolysaccharide core acceptor for ligation of O antigens in the genus Salmonella: WaaL "ligase" is not the sole determinant of acceptor specificity
    Natalia A Kaniuk
    Department of Microbiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    J Biol Chem 279:36470-80. 2004
    ..The data provide the first indication of a more complicated recognition process involving additional cellular components...
  74. ncbi Cold temperature-induced modifications to the composition and structure of the lipopolysaccharide of Yersinia pestis
    Yuriy A Knirel
    N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia
    Carbohydr Res 340:1625-30. 2005
    ..The data obtained suggest that cold temperature switches on an alternative mechanism of control of the synthesis of Y. pestis LPS...
  75. ncbi Characterization of the lipopolysaccharide and beta-glucan of the fish pathogen Francisella victoria
    William Kay
    Department of Biochemistry and Microbiology, University of Victoria, BC, Canada
    FEBS J 273:3002-13. 2006
    ..LPS preparation contained two characteristic glucans, previously observed as components of LPS preparations from other strains of Francisella: amylose and the unusual beta-(1-6)-glucan with (glycerol)2phosphate at the reducing end...
  76. ncbi Chromosomal and plasmid-encoded enzymes are required for assembly of the R3-type core oligosaccharide in the lipopolysaccharide of Escherichia coli O157:H7
    Natalia A Kaniuk
    Department of Microbiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    J Biol Chem 279:31237-50. 2004
    ..coli O157 and Shigella flexneri serotype 2a. This is the first plasmid-encoded core oligosaccharide biosynthesis enzyme reported in E. coli...
  77. ncbi O-Acetylation in the O-specific polysaccharide isolated from Shigella flexneri serotype 2a
    Joanna Kubler-Kielb
    National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Carbohydr Res 342:643-7. 2007
    ..Here, we report the degree of O-acetylation and the localisation of O-acetyl groups and side-chain glucose substitution in the O-SP (scheme) in different preparations of S. flexneri type 2a LPS. [structure: see text]..
  78. ncbi lfnA from Pseudomonas aeruginosa O12 and wbuX from Escherichia coli O145 encode membrane-associated proteins and are required for expression of 2,6-dideoxy-2-acetamidino-L-galactose in lipopolysaccharide O antigen
    Jerry D King
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    J Bacteriol 190:1671-9. 2008
    ..Both proteins retained their activity when fused to a His(6) tag and localized to the membrane fraction. These data will assist future biochemical investigation of this pathway...
  79. ncbi Structural and biological characterization of a capsular polysaccharide produced by Staphylococcus haemolyticus
    Sigrid Flahaut
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Bacteriol 190:1649-57. 2008
    ..This structure is unique among staphylococcal polysaccharides in that its composition includes a trideoxy sugar residue with aspartic acid as an N-acyl substituent...
  80. ncbi Functional characterization of MigA and WapR: putative rhamnosyltransferases involved in outer core oligosaccharide biosynthesis of Pseudomonas aeruginosa
    Karen K H Poon
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON N1G 2W1, Canada
    J Bacteriol 190:1857-65. 2008
    ..In contrast, uncapped core OS from the migA mutant lacked alpha-1,6-L-Rha. These results provide evidence that WapR is the alpha-1,3-rhamnosyltransferase, while MigA is the alpha-1,6-rhamnosyltransferase...
  81. ncbi Poly-N-acetylglucosamine mediates biofilm formation and detergent resistance in Aggregatibacter actinomycetemcomitans
    Era A Izano
    Department of Oral Biology, New Jersey Dental School, 185 S Orange Avenue, Newark, NJ 07103, USA
    Microb Pathog 44:52-60. 2008
    ..Our findings suggest that PGA, extracellular DNA and proteinaceous adhesins all contribute to the structural integrity of the A. actinomycetemcomitans biofilm matrix...
  82. ncbi Full structure of the carbohydrate chain of the lipopolysaccharide of Providencia rustigianii O34
    Nina A Kocharova
    N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russian Federation
    Chemistry 14:6184-91. 2008
    ..Combining the structure of the carbohydrate moiety thus determined and the known structure of lipid A enabled determination of the full lipopolysaccharide structure of P. rustigianii O34...
  83. ncbi Structural studies on the lipopolysaccharide core of Proteus OX strains used in Weil-Felix test: a mass spectrometric approach
    Anna N Kondakova
    N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47, 119991 Moscow, Russian Federation
    Carbohydr Res 338:2697-709. 2003
    ....
  84. ncbi Biosynthesis of a novel 3-deoxy-D-manno-oct-2-ulosonic acid-containing outer core oligosaccharide in the lipopolysaccharide of Klebsiella pneumoniae
    Emilisa Frirdich
    Department of Microbiology, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada
    J Biol Chem 279:27928-40. 2004
    ..The activated precursor required for GlcN addition has not been identified. However, lysates overexpressing WabH were able to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the outer core...
  85. ncbi Mesophilic Aeromonas UDP-glucose pyrophosphorylase (GalU) mutants show two types of lipopolysaccharide structures and reduced virulence
    Silvia Vilches
    Departamento de Microbiologia, Facultad de Biologia, Universidad de Barcelona, Diagonal 645, 08071 Barcelona, Spain
    Microbiology 153:2393-404. 2007
    ..5 or 2 log units the virulence of Aeromonas serotype O34 strains in a septicaemia model in either fish or mice. All the changes observed in the galU mutants were rescued by the introduction of the corresponding single wild-type gene...
  86. ncbi Poly-N-acetylglucosamine mediates biofilm formation and antibiotic resistance in Actinobacillus pleuropneumoniae
    Era A Izano
    Department of Oral Biology, New Jersey Dental School, Newark, NJ 07103, USA
    Microb Pathog 43:1-9. 2007
    ..Our findings suggest that PGA functions as a major biofilm adhesin in A. pleuropneumoniae. Biofilm formation may have relevance to the colonization and pathogenesis of A. pleuropneumoniae in pigs...
  87. ncbi PagP activation in the outer membrane triggers R3 core oligosaccharide truncation in the cytoplasm of Escherichia coli O157:H7
    Abigail E Smith
    Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    J Biol Chem 283:4332-43. 2008
    ..We discuss the implication that PagP might function as an apical sensory transducer, which can be activated by a breach in the outer membrane permeability barrier...