R Anthony Shaw

Summary

Affiliation: National Research Council
Country: Canada

Publications

  1. ncbi Toward point-of-care diagnostic metabolic fingerprinting: quantification of plasma creatinine by infrared spectroscopy of microfluidic-preprocessed samples
    R Anthony Shaw
    National Research Council of Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    Analyst 134:1224-31. 2009
  2. ncbi Relative contributions of hemoglobin and myoglobin to near-infrared spectroscopic images of cardiac tissue
    Stephen P Nighswander-Rempel
    Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    Appl Spectrosc 59:190-3. 2005
  3. ncbi Metabolic fingerprinting of biofluids by infrared spectroscopy: modeling and optimization of flow rates for laminar fluid diffusion interface sample preconditioning
    Bernhard Schattka
    National Research Council of Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    Anal Chem 83:555-62. 2011
  4. ncbi Quantification of serum apolipoprotein B by infrared spectroscopy
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council of Canada, 435 Ellice Avenue, Winnipeg, Manitoba, R3B 1Y6, Canada
    Anal Bioanal Chem 387:1809-14. 2007
  5. ncbi Laminar fluid diffusion interface preconditioning of serum and urine for reagent-free infrared clinical analysis and diagnostics
    Colin D Mansfield
    Institute for Biodiagnostics, National Research Council Canada, 435 Ellice Ave, Winnipeg, Manitoba, Canada
    Appl Spectrosc 59:10-5. 2005
  6. ncbi Regional cardiac tissue oxygenation as a function of blood flow and pO2: A near-infrared spectroscopic imaging study
    Stephen P Nighswander-Rempel
    National Research Council of Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba R3B 1Y6, Canada
    J Biomed Opt 11:054004. 2006
  7. ncbi Molecular determination of liver fibrosis by synchrotron infrared microspectroscopy
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council of Canada, Winnipeg, MB, Canada R3B 1Y6
    Biochim Biophys Acta 1758:960-7. 2006
  8. ncbi Assessment of optical path length in tissue using neodymium and water absorptions for application to near-infrared spectroscopy
    Stephen P Nighswander-Rempel
    Institute for Biodiagnostics, 435 Ellice Ave, Winnipeg, Manitoba R3B 1Y6
    J Biomed Opt 10:024023. 2005
  9. ncbi Infrared spectroscopic identification of beta-thalassemia
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council of Canada, 435 Ellice Avenue, Winnipeg, Manitoba, R3B 1Y6 Canada
    Clin Chem 49:1125-32. 2003
  10. ncbi Detection of myocardial cell damage in isolated rat hearts with near-infrared spectroscopy
    Stephen P Nighswander-Rempel
    Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba R3B 1Y6 Canada
    J Biomed Opt 9:779-87. 2004

Collaborators

Detail Information

Publications12

  1. ncbi Toward point-of-care diagnostic metabolic fingerprinting: quantification of plasma creatinine by infrared spectroscopy of microfluidic-preprocessed samples
    R Anthony Shaw
    National Research Council of Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    Analyst 134:1224-31. 2009
    ..Preliminary results of diffusion modeling are reported, and the prospects for further optimization of the technique, guided by accurate modeling, are discussed...
  2. ncbi Relative contributions of hemoglobin and myoglobin to near-infrared spectroscopic images of cardiac tissue
    Stephen P Nighswander-Rempel
    Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    Appl Spectrosc 59:190-3. 2005
    ....
  3. ncbi Metabolic fingerprinting of biofluids by infrared spectroscopy: modeling and optimization of flow rates for laminar fluid diffusion interface sample preconditioning
    Bernhard Schattka
    National Research Council of Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    Anal Chem 83:555-62. 2011
    ..The flow rates thus derived provided a LFDI product that is relatively rich in serum metabolites, while largely depleted of protein, and very well suited for subsequent IR spectroscopic characterization...
  4. ncbi Quantification of serum apolipoprotein B by infrared spectroscopy
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council of Canada, 435 Ellice Avenue, Winnipeg, Manitoba, R3B 1Y6, Canada
    Anal Bioanal Chem 387:1809-14. 2007
    ....
  5. ncbi Laminar fluid diffusion interface preconditioning of serum and urine for reagent-free infrared clinical analysis and diagnostics
    Colin D Mansfield
    Institute for Biodiagnostics, National Research Council Canada, 435 Ellice Ave, Winnipeg, Manitoba, Canada
    Appl Spectrosc 59:10-5. 2005
    ..Observations from simulated and genuine urine and serum samples strongly suggest that this process should improve existing accuracy and extend the range of detectable analytes...
  6. ncbi Regional cardiac tissue oxygenation as a function of blood flow and pO2: A near-infrared spectroscopic imaging study
    Stephen P Nighswander-Rempel
    National Research Council of Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba R3B 1Y6, Canada
    J Biomed Opt 11:054004. 2006
    ..These results suggest that NIRSI is well suited, not only to identify ischemic or hypoxic regions of cardiac tissue, but also to assess the severity of deoxygenation...
  7. ncbi Molecular determination of liver fibrosis by synchrotron infrared microspectroscopy
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council of Canada, Winnipeg, MB, Canada R3B 1Y6
    Biochim Biophys Acta 1758:960-7. 2006
    ..We therefore suggest that infrared microspectroscopy may provide an additional and sensitive means for the early detection of liver fibrosis...
  8. ncbi Assessment of optical path length in tissue using neodymium and water absorptions for application to near-infrared spectroscopy
    Stephen P Nighswander-Rempel
    Institute for Biodiagnostics, 435 Ellice Ave, Winnipeg, Manitoba R3B 1Y6
    J Biomed Opt 10:024023. 2005
    ..8+/-0.6 mm, based on the intensity of the water absorptions and the known tissue water concentration. These results are strictly valid only for the experimental geometry applied here...
  9. ncbi Infrared spectroscopic identification of beta-thalassemia
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council of Canada, 435 Ellice Avenue, Winnipeg, Manitoba, R3B 1Y6 Canada
    Clin Chem 49:1125-32. 2003
    ..The aim of this study was to investigate the potential of infrared (IR) spectroscopy as a fast and reagent-free adjunct tool in the diagnosis and screening of beta-thalassemia...
  10. ncbi Detection of myocardial cell damage in isolated rat hearts with near-infrared spectroscopy
    Stephen P Nighswander-Rempel
    Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba R3B 1Y6 Canada
    J Biomed Opt 9:779-87. 2004
    ..No apparent dependence of total membrane disruption on digitonin concentration over the concentration range studied is found, although higher concentrations do lead to more rapid membrane disruption...
  11. ncbi Use of Fourier-transform infrared spectroscopy for the diagnosis of failure of transfer of passive immunity and measurement of immunoglobulin concentrations in horses
    Christopher B Riley
    National Research Council of Canada, Institute for Biodiagnostics, Winnipeg, MB
    J Vet Intern Med 21:828-34. 2007
    ..The economic, accurate, and rapid screening of foals for failure of transfer of passive immunity (FPT) is essential to ensure timely intervention...
  12. ncbi Reagent-free, simultaneous determination of serum cholesterol in HDL and LDL by infrared spectroscopy
    Kan Zhi Liu
    Institute for Biodiagnostics, National Research Council Canada, 435 Ellice Ave, Winnipeg, Manitoba, R3B 1Y6, Canada
    Clin Chem 48:499-506. 2002
    ..The purpose of this study was to assess the feasibility of infrared (IR) spectroscopy for the simultaneous quantification of serum LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) concentrations...