Maria J Moreno

Summary

Affiliation: National Research Council
Country: Canada

Publications

  1. ncbi request reprint Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells
    Maria J Moreno
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    Glia 53:845-57. 2006
  2. ncbi request reprint Insulin-like growth factor binding protein 7 exhibits tumor suppressive and vessel stabilization properties in U87MG and T98G glioblastoma cell lines
    Ally Pen
    Institute for Biological Sciences, National Research Council of Canada, Montreal, QC, Canada
    Cancer Biol Ther 12:634-46. 2011
  3. pmc IGFBP-4 Anti-Angiogenic and Anti-Tumorigenic Effects Are Associated with Anti-Cathepsin B Activity
    Maria J Moreno
    National Research Council of Canada, Ottawa, Ontario, Canada
    Neoplasia 15:554-67. 2013
  4. pmc PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge
    Moises Freitas-Andrade
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    J Cereb Blood Flow Metab 32:663-75. 2012
  5. ncbi request reprint Molecular markers of extracellular matrix remodeling in glioblastoma vessels: microarray study of laser-captured glioblastoma vessels
    Ally Pen
    Cerebrovascular Research Group, Neurobiology Program, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    Glia 55:559-72. 2007
  6. doi request reprint Identification of secreted proteins regulated by cAMP in glioblastoma cells using glycopeptide capture and label-free quantification
    Jennifer J Hill
    Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada
    Proteomics 9:535-49. 2009

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells
    Maria J Moreno
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    Glia 53:845-57. 2006
    ..IGFBP-4 is a novel dB-cAMP-induced anti-angiogenic and anti-tumorigenic mediator that may be a promising candidate for glioblastoma therapy...
  2. ncbi request reprint Insulin-like growth factor binding protein 7 exhibits tumor suppressive and vessel stabilization properties in U87MG and T98G glioblastoma cell lines
    Ally Pen
    Institute for Biological Sciences, National Research Council of Canada, Montreal, QC, Canada
    Cancer Biol Ther 12:634-46. 2011
    ..This study indicates that IGFBP7 suppresses U87MG tumor cell growth, induces cell senescence and participates in tumor vessel stabilization by promoting SMC/pericyte recruitment and differentiation...
  3. pmc IGFBP-4 Anti-Angiogenic and Anti-Tumorigenic Effects Are Associated with Anti-Cathepsin B Activity
    Maria J Moreno
    National Research Council of Canada, Ottawa, Ontario, Canada
    Neoplasia 15:554-67. 2013
    ..Most importantly, CIBP-4 reduced tumor growth in this animal model by 60%. Pleiotropic anti-angiogenic and anti-tumorigenic activities of CIBP-4 most likely underlie its observed therapeutic potential against glioblastoma...
  4. pmc PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge
    Moises Freitas-Andrade
    Cerebrovascular Research Group, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    J Cereb Blood Flow Metab 32:663-75. 2012
    ....
  5. ncbi request reprint Molecular markers of extracellular matrix remodeling in glioblastoma vessels: microarray study of laser-captured glioblastoma vessels
    Ally Pen
    Cerebrovascular Research Group, Neurobiology Program, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
    Glia 55:559-72. 2007
    ..The study discerns unique molecular characteristics of GBM vessels compared with nonmalignant brain vessels that could potentially be used for diagnostic or therapeutic purposes...
  6. doi request reprint Identification of secreted proteins regulated by cAMP in glioblastoma cells using glycopeptide capture and label-free quantification
    Jennifer J Hill
    Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada
    Proteomics 9:535-49. 2009
    ..Overall, these results demonstrate the benefits of using a highly specific enrichment method for quantitative proteomic experiments...