R Mackenzie

Summary

Affiliation: National Research Council
Country: Canada

Publications

  1. ncbi request reprint Quantitative analysis of bacterial toxin affinity and specificity for glycolipid receptors by surface plasmon resonance
    C R MacKenzie
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
    J Biol Chem 272:5533-8. 1997
  2. ncbi request reprint The role of valency in the selection of anti-carbohydrate single-chain Fvs from phage display libraries
    R Mackenzie
    Institute for Biological Sciences, National Research Council Canada, Ottawa, Ontario
    J Immunol Methods 220:39-49. 1998
  3. doi request reprint Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points
    M Arbabi-Ghahroudi
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada K1A 0R6
    Protein Eng Des Sel 22:59-66. 2009

Collaborators

  • E Altman
  • M Arbabi-Ghahroudi
  • T Hirama
  • N Gaudette
  • J Tanha
  • W Ding
  • R To
  • C R MacKenzie
  • N M Young
  • K K Lee

Detail Information

Publications3

  1. ncbi request reprint Quantitative analysis of bacterial toxin affinity and specificity for glycolipid receptors by surface plasmon resonance
    C R MacKenzie
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
    J Biol Chem 272:5533-8. 1997
    ..The SPR/liposome technology should have general applicability in the study of glycolipid-protein interactions and in the evaluation of reagents designed to interfere with these interactions...
  2. ncbi request reprint The role of valency in the selection of anti-carbohydrate single-chain Fvs from phage display libraries
    R Mackenzie
    Institute for Biological Sciences, National Research Council Canada, Ottawa, Ontario
    J Immunol Methods 220:39-49. 1998
    ..It is suggested that the multivalency of display provided by phage vectors is preferable to any phagemid vector strategy for the de novo isolation of anti-carbohydrate antibodies from phage libraries...
  3. doi request reprint Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points
    M Arbabi-Ghahroudi
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada K1A 0R6
    Protein Eng Des Sel 22:59-66. 2009
    ..In addition, calculation of theoretical pIs of V(H)s selected by panning may be used for rapid and precise identification of non-aggregating V(H)s...