Affiliation: National Research Council
- Quantitative analysis of bacterial toxin affinity and specificity for glycolipid receptors by surface plasmon resonanceC R MacKenzie
Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
J Biol Chem 272:5533-8. 1997..The SPR/liposome technology should have general applicability in the study of glycolipid-protein interactions and in the evaluation of reagents designed to interfere with these interactions...
- The role of valency in the selection of anti-carbohydrate single-chain Fvs from phage display librariesR Mackenzie
Institute for Biological Sciences, National Research Council Canada, Ottawa, Ontario
J Immunol Methods 220:39-49. 1998..It is suggested that the multivalency of display provided by phage vectors is preferable to any phagemid vector strategy for the de novo isolation of anti-carbohydrate antibodies from phage libraries...
- Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric pointsM Arbabi-Ghahroudi
Institute for Biological Sciences, National Research Council of Canada, Ottawa, ON, Canada K1A 0R6
Protein Eng Des Sel 22:59-66. 2009..In addition, calculation of theoretical pIs of V(H)s selected by panning may be used for rapid and precise identification of non-aggregating V(H)s...