Alex C T Ko

Summary

Affiliation: National Research Council
Country: Canada

Publications

  1. doi request reprint Multimodal nonlinear optical imaging of atherosclerotic plaque development in myocardial infarction-prone rabbits
    Alex C T Ko
    National Research Council Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    J Biomed Opt 15:020501. 2010
  2. pmc Collagen morphology and texture analysis: from statistics to classification
    Leila B Mostaço-Guidolin
    National Research Council Canada, Medical Devices Portfolio 435 Ellice Avenue, Winnipeg, MB, Canada R3B 1Y6
    Sci Rep 3:2190. 2013
  3. ncbi request reprint Quantitative nonlinear optical assessment of atherosclerosis progression in rabbits
    Leila B Mostaço-Guidolin
    National Research Council Canada, Medical Devices Portfolio, 435 Ellice Avenue, Winnipeg, MB, Canada R3B 1Y6
    Anal Chem 86:6346-54. 2014
  4. doi request reprint Evaluation of texture parameters for the quantitative description of multimodal nonlinear optical images from atherosclerotic rabbit arteries
    Leila B Mostaço-Guidolin
    Institute for Biodiagnostics, National Research Council Canada, Winnipeg, R3B 1Y6, Canada
    Phys Med Biol 56:5319-34. 2011
  5. ncbi request reprint Ex vivo detection and characterization of early dental caries by optical coherence tomography and Raman spectroscopy
    Alex C T Ko
    National Research Council Canada, Institute for Biodiagnostics, 435 Ellice Ave, Winnipeg MB, Canada R3B 1Y6
    J Biomed Opt 10:031118. 2005

Collaborators

Detail Information

Publications6

  1. doi request reprint Multimodal nonlinear optical imaging of atherosclerotic plaque development in myocardial infarction-prone rabbits
    Alex C T Ko
    National Research Council Canada, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, Manitoba, Canada R3B 1Y6
    J Biomed Opt 15:020501. 2010
    ..Clear pathological changes are observed in the extracellular matrix of the arterial wall and correlated with progression of atherosclerotic disease as represented by the age of the WHHLMI rabbits...
  2. pmc Collagen morphology and texture analysis: from statistics to classification
    Leila B Mostaço-Guidolin
    National Research Council Canada, Medical Devices Portfolio 435 Ellice Avenue, Winnipeg, MB, Canada R3B 1Y6
    Sci Rep 3:2190. 2013
    ..The proposed methodology can be applied to a wide range of conditions involving collagen re-modeling, such as in skin disorders, different types of fibrosis and muscular-skeletal diseases affecting ligaments and cartilage...
  3. ncbi request reprint Quantitative nonlinear optical assessment of atherosclerosis progression in rabbits
    Leila B Mostaço-Guidolin
    National Research Council Canada, Medical Devices Portfolio, 435 Ellice Avenue, Winnipeg, MB, Canada R3B 1Y6
    Anal Chem 86:6346-54. 2014
    ..The same optical index also accurately identified high-risk locations for atherosclerotic plaque formation along the entire aorta, which was validated by immunohistochemical fluorescence imaging. ..
  4. doi request reprint Evaluation of texture parameters for the quantitative description of multimodal nonlinear optical images from atherosclerotic rabbit arteries
    Leila B Mostaço-Guidolin
    Institute for Biodiagnostics, National Research Council Canada, Winnipeg, R3B 1Y6, Canada
    Phys Med Biol 56:5319-34. 2011
    ..Tonal and texture parameters from NLO images provide objective metrics that correspond to structural and biochemical changes that occur within the vessel wall in early and late stage atherosclerosis...
  5. ncbi request reprint Ex vivo detection and characterization of early dental caries by optical coherence tomography and Raman spectroscopy
    Alex C T Ko
    National Research Council Canada, Institute for Biodiagnostics, 435 Ellice Ave, Winnipeg MB, Canada R3B 1Y6
    J Biomed Opt 10:031118. 2005
    ..The combination has potential for development into a new fiber-optic diagnostic tool enabling dentists to identify early caries lesions with greater sensitivity and specificity...