A D Cox
Affiliation: National Research Council
Cox A, St Michael F, Aubry A, Cairns C, Strong P, Hayes A, et al
. Investigating the candidacy of a lipoteichoic acid-based glycoconjugate as a vaccine to combat Clostridium difficile infection. Glycoconj J. 2013;30:843-55 pubmed publisher
..This study has illustrated that the LTA polymer is a highly conserved surface polymer of C. difficile that is easily accessible to the immune system and as such merits consideration as a vaccine antigen to combat C. difficile infection...
Salman M, St Michael F, Ali A, Jabbar A, Cairns C, Hayes A, et al
. First characterization of immunogenic conjugates of Vi negative Salmonella Typhi O-specific polysaccharides with rEPA protein for vaccine development. J Immunol Methods. 2017;450:27-33 pubmed publisher
..Typhi OSP glycoconjugate. Moreover, rEPA was a better carrier protein than HSA. Thus OSP-rEPA conjugate seems to be efficacious typhoid vaccines candidate, it may be evaluated further and recommended for the clinical trials. ..
Cox A, Williams D, Cairns C, St Michael F, Fleming P, Vinogradov E, et al
. Investigating the candidacy of a capsular polysaccharide-based glycoconjugate as a vaccine to combat Haemophilus influenzae type a disease: A solution for an unmet public health need. Vaccine. 2017;35:6129-6136 pubmed publisher
..This study has illustrated the pre-clinical proof of concept of a glycoconjugate vaccine based on the CPS of Hia asa solution to this emerging disease. ..
St Michael F, Yang Q, Cairns C, Vinogradov E, Fleming P, Hayes A, et al
. Investigating the candidacy of the serotype specific rhamnan polysaccharide based glycoconjugates to prevent disease caused by the dental pathogen Streptococcus mutans. Glycoconj J. 2018;35:53-64 pubmed publisher
..We conclude that glycoconjugates of the rhamnan polymers of S. mutans are a potential vaccine candidate to target dental caries and other sequelae following the escape of S. mutans from the oral cavity. ..