Research Topics
| J M StewartSummaryAffiliation: Mount Allison University Country: Canada Publications
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Detail Information
Publications
Maximal enzyme activities, and myoglobin and glutathione concentrations in heart, liver and skeletal muscle of the Northern Short-tailed shrew (Blarina brevicauda; Insectivora: Soricidae)J M Stewart
Biochemistry Programme, Department of Biology, Mount Allison University, Flemington Building, 63B York St Sackville, NB, Canada E4L 1G7
Comp Biochem Physiol B Biochem Mol Biol 141:267-73. 2005..The potential for generation of reactive oxygen species must be great since the total glutathione concentration (165 mumol/g) is 300-fold greater in shrew hearts than in hearts of rats...
Unusually weak oxygen binding, physical properties, partial sequence, autoxidation rate and a potential phosphorylation site of beluga whale (Delphinapterus leucas) myoglobinJ M Stewart
Biochemistry Programme, Department of Biology, Mount Allison University, Flemington Bldg, 63B York St Sackville, NB, Canada E4L 1G7
Comp Biochem Physiol B Biochem Mol Biol 137:401-12. 2004..Structural models based on the protein sequence and constructed on topologies of known templates (horse and sperm whale crystal structures) were not adequate to assess perturbation of the heme pocket...
The interaction of ferrocytochrome c with long-chain fatty acids and their CoA and carnitine estersJ M Stewart
Department of Biology, Mount Allison University, Sackville, NB, Canada
Biochem Cell Biol 78:675-81. 2000..From molecular modeling we identify a putative binding channel flanked by lysines 72 and 73...
The cytoplasmic fatty-acid-binding proteins: thirty years and countingJ M Stewart
Department of Biology, Mount Allison University, Sackville, New Brunswick, Canada
Cell Mol Life Sci 57:1345-59. 2000..This large protein family may be integral in the relationship between lipid and carbohydrate metabolism...
The muscle fatty acid binding protein of spadefoot toad (Scaphiopus couchii)J M Stewart
Department of Biology, Mount Allison University, Sackville, NB, Canada
Comp Biochem Physiol B Biochem Mol Biol 125:347-57. 2000..The interaction of this fatty acid transporter with fructose 1,6-bisphosphate is discussed in terms of reciprocal interaction with phosphofructokinase since fatty acid is also an inhibitor of phosphofructokinase...
Long chain fatty acids inhibit and medium chain fatty acids activate mammalian cardiac hexokinaseJ M Stewart
Biochemistry Program, Department of Biology, Mount Allison University, Flemington Building, 63B York St E4L 1G7, Sackville, NB, Canada
Biochim Biophys Acta 1484:278-86. 2000..026+/-0.003 mM) was not significantly different from the control (0.014+/-0.004 mM). A decrease in V(max) values in the presence of oleate indicated that a mixed allosteric inhibition was operating...
Comparisons of the effects of temperature on the liver fatty acid binding proteins from hibernator and nonhibernator mammalsJ M Stewart
Department of Biology and Biochemistry, Mount Allison University, Sackville, NB, Canada
Biochem Cell Biol 76:593-9. 1998..Rat protein was clearly not adapted to function optimally at temperatures lower than the animal's body temperature...
Fatty acid binding to rat liver fatty acid-binding protein is modulated by early glycolytic intermediatesJ M Stewart
Department of Biology and Biochemistry, Mount Allison University, Sackville, New Brunswick, Canada
Biochim Biophys Acta 1391:1-6. 1998..Binding decreased logarithmically with ionic strength. Glucose and glucose-6-phosphate increased fatty acid binding significantly with K0.5 within physiological ranges while glucose-1-phosphate and phosphate ion caused no effect...
Ferriheme and ferroheme are isosteric inhibitors of fatty acid binding to rat liver fatty acid binding proteinJ M Stewart
Mount Allison University, Sackville, Canada
Biochem Cell Biol 74:249-55. 1996..This suggested that the binding affinity of fatty acid binding protein for iron-deuteroporphyrin is too great to allow rapid equilibrium between bound and unbound ligand across the system in an appropriate time frame...
A fluorescent compound for glucose uptake measurements in isolated rat cardiomyocytesS W Ball
Department of Biology, Mount Allison University, Sackville, Canada
Can J Physiol Pharmacol 80:205-9. 2002..040 nmol x min(-1) x 10(6) cells(-1), demonstrating the validity of this fluorescent compound for glucose uptake studies...
