Research Topics
| Vibhuti ShahSummaryAffiliation: Mount Sinai Hospital Country: Canada Publications
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Detail Information
Publications
Early administration of inhaled corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonatesVibhuti S Shah
Department of Paediatrics and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
Cochrane Database Syst Rev 5:CD001969. 2012..Theoretically, administration of inhaled corticosteroids may allow for beneficial effects on the pulmonary system with a lower risk of undesirable systemic side effects...
Topical amethocaine gel 4% for intramuscular injection in term neonates: a double-blind, placebo-controlled, randomized trialVibhuti S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Clin Ther 30:166-74. 2008..They have been found to attenuate pain from various procedures, including intramuscular (i.m.) injection of vaccines. Published data on their effectiveness for i.m. injection of vitamin K in neonates were not identified...
The effectiveness of premedication for endotracheal intubation in mechanically ventilated neonates. A systematic reviewVibhuti Shah
Department of Paediatrics, Mount Sinai Hospital, Faculty of Medicine, University of Toronto, 600 University Avenue, Toronto, ON M5G 1X5, Canada
Clin Perinatol 29:535-54. 2002..A valid pain assessment measure or approach should be used. Both short-term and long-term physiologic and clinical outcomes should be incorporated into the trial design...
Association between hematologic findings and brain injury due to neonatal hypoxic-ischemic encephalopathyVibhuti Shah
Department of Paediatrics, Mount Sinai Hospital, Ontario, Canada
Am J Perinatol 26:295-302. 2009..The characteristic hematologic changes found are attributable to the asphyxial insults, not to brain injury. Because of inconsistent changes, hematologic counts cannot be used on their own to time asphyxial insults...
Evaluation of a new lancet device (BD QuikHeel) on pain response and success of procedure in term neonatesVibhuti Shah
Department of Paediatrics and Nursing, Mount Sinai Hospital, Toronto, Ontario, Canada
Arch Pediatr Adolesc Med 157:1075-8. 2003..To evaluate 2 heel lancet devices in terms of pain response and success of the procedure in neonates undergoing the newborn screening test...
Neonatal outcomes among multiple births ≤ 32 weeks gestational age: does mode of conception have an impact? A cohort studyVibhuti Shah
Department of Paediatrics, Room 775A, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada
BMC Pediatr 11:54. 2011..Therefore, the objective of our study was to compare composite outcome of mortality and severe neonatal morbidities amongst preterm multiple births ≤ 32 weeks gestation infant born following ART vs. SC...
Effectiveness and tolerability of pharmacologic and combined interventions for reducing injection pain during routine childhood immunizations: systematic review and meta-analysesVibhuti Shah
Department of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Clin Ther 31:S104-51. 2009..To date, no systematic review has been published on the effectiveness of pharmacologic and combined interventions for reducing injection pain...
Effectiveness of sucrose analgesia in newborns undergoing painful medical proceduresAnna Taddio
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
CMAJ 179:37-43. 2008..Our objectives were to evaluate the effectiveness and safety of sucrose in newborns undergoing various medical procedures within 2 days of birth...
Physical interventions and injection techniques for reducing injection pain during routine childhood immunizations: systematic review of randomized controlled trials and quasi-randomized controlled trialsAnna Taddio
Division of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Clin Ther 31:S48-76. 2009..Their effectiveness, however, has not previously been studied using a systematic approach...
Air pollution and birth outcomes: a systematic reviewPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Environ Int 37:498-516. 2011....
Influence of repeated painful procedures and sucrose analgesia on the development of hyperalgesia in newborn infantsAnna Taddio
Pharmacy Practice Division, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
Pain 144:43-8. 2009..In conclusion, sucrose analgesia for repeated painful procedures in the first day of life does not prevent development of remote hyperalgesia in newborns...
Induced termination of pregnancy and low birthweight and preterm birth: a systematic review and meta-analysesP S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada
BJOG 116:1425-42. 2009..Infection, mechanical trauma to the cervix leading to cervical incompetence and scarred tissue following curettage are suspected mechanisms...
Effect of liposomal lidocaine and sucrose alone and in combination for venipuncture pain in newbornsAnna Taddio
Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College St, Toronto, Ontario, Canada M5S 3M2
Pediatrics 127:e940-7. 2011..To determine the relative effectiveness of liposomal lidocaine, sucrose, and their combination for reducing pain in term newborns...
Influence of the maternal birth status on offspring: a systematic review and meta-analysisPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada
Acta Obstet Gynecol Scand 88:1307-18. 2009..Maternal low birth weight (LBW), preterm birth (PTB) and small-for-gestational age (SGA) birth status have been suggested as precursors for an infant being born LBW, PTB or SGA...
Effects of cocaine use during pregnancy on low birthweight and preterm birth: systematic review and metaanalysesKaty Gouin
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada
Am J Obstet Gynecol 204:340.e1-12. 2011..To review systematically maternal antenatal cocaine exposure and adverse perinatal outcomes...
Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic reviewPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, and the Departments of Pediatrics and of Health Policy, Management and Evaluations, University of Toronto, Toronto, Ontario, Canada
Am J Obstet Gynecol 202:103-23. 2010..In conclusion, paternal characteristics including age, height, and birthweight are associated with LBW. Paternal occupational exposure and low levels of education may be associated with LBW; however, further studies are needed...
Routine immunization practices: use of topical anesthetics and oral analgesicsAnna Taddio
Department of Pharmacy, Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
Pediatrics 120:e637-43. 2007..Our objective was to evaluate analgesic use during childhood immunization...
A single preoperative dose of gabapentin does not improve postcesarean delivery pain management: a randomized, double-blind, placebo-controlled dose-finding trialJonathan Short
Department of Anesthesia and Pain Management, Mount Sinai Hospital, 600 University Avenue, Room 781, Toronto, ON, Canada
Anesth Analg 115:1336-42. 2012..We hypothesized that a lower dose of gabapentin may be effective with less sedation...
Maternal exposure to domestic violence and pregnancy and birth outcomes: a systematic review and meta-analysesPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Canada
J Womens Health (Larchmt) 19:2017-31. 2010..Our objective was to systematically review birth outcomes among women who experienced domestic violence...
Maternal marital status and birth outcomes: a systematic review and meta-analysesPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, 775A 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada
Matern Child Health J 15:1097-109. 2011..36, 95%CI 1.30-1.42) mothers. Meta-analyses of adjusted odds estimates confirmed these findings at marginally lower odds. Maternal unmarried status is associated with an increased risk of LBW, PTB and SGA births...
Reduced infant response to a routine care procedure after sucrose analgesiaAnna Taddio
University of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada
Pediatrics 123:e425-9. 2009..Our objective was to determine the effect of sucrose analgesia for procedural pain on infant pain responses during a subsequent caregiving procedure...
Effects of the September 11, 2001 disaster on pregnancy outcomes: a systematic reviewArne Ohlsson
Department of Pediatrics, Mount Sinai Hospital, University of Toronto, Canada
Acta Obstet Gynecol Scand 90:6-18. 2011..Pregnant women and their offspring are especially vulnerable during and after such a terrorist attack. The objective was to systematically review the risks of adverse pregnancy outcomes after the terrorist attacks on Sept 11, 2001...
Intravenous morphine and topical tetracaine for treatment of pain in [corrected] neonates undergoing central line placementAnna Taddio
Department of Pharmacy, The Hospital for Sick Children, Faculty of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario
JAMA 295:793-800. 2006..There is limited evidence of the analgesic effectiveness of opioid analgesia or topical anesthesia during central line placement in neonates, and there are no previous studies of their relative effectiveness...
Environmental tobacco smoke exposure and perinatal outcomes: a systematic review and meta-analysesGiselle Salmasi
Department of Health Sciences, McMaster University, Hamilton, Ontario, Canada
Acta Obstet Gynecol Scand 89:423-41. 2010..While active maternal tobacco smoking has well established adverse perinatal outcomes, the effects of passive maternal smoking, also called environmental tobacco exposure (ETS), are less well studied and less consistent...
Inadequate pain management during routine childhood immunizations: the nerve of itAnna Taddio
Division of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Clin Ther 31:S152-67. 2009..Immunization is regarded as one of the most significant medical achievements of all time. Recently, increasing attention has been paid to the pain resulting from routine childhood immunizations...
Safety of morphine in nonintubated infants in the neonatal intensive care unitAnna Taddio
Pharmacy Practice Division, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
Clin J Pain 25:418-22. 2009..To determine the safety of morphine for procedural pain management in nonintubated infants in the neonatal intensive care unit...
Variability in clinical practice guidelines for sweetening agents in newborn infants undergoing painful proceduresAnna Taddio
Department of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada
Clin J Pain 25:153-5. 2009..The objective of this study was to investigate unit-specific protocols for the use of sweetening agents...
Breastfeeding or breastmilk to alleviate procedural pain in neonates: a systematic reviewPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Breastfeed Med 2:74-82. 2007..To (1) compare breastfeeding with control (placebo, no treatment, sucrose, glucose, pacifiers, or positioning) and (2) compare breastmilk with control for procedural pain in neonates...
Comparison of pain during two methods of urine collection in preterm infantsWalid El-Naggar
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
Pediatrics 125:1224-9. 2010..Suprapubic aspiration (SPA) and urine catheterization (UC) are performed frequently in preterm neonates to rule out urinary tract infection; however, a comparison of the pain caused by both procedures has not been made previously...
Canadian neonatologist practices regarding opioid use in ventilated and spontaneously breathing infants undergoing medical proceduresAnna Taddio
Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada
Clin J Pain 26:422-8. 2010..Opioids are indicated for the management of procedural pain in neonates. There are limited data describing factors influencing patterns of use...
A randomized, controlled trial of heparin versus placebo infusion to prolong the usability of peripherally placed percutaneous central venous catheters (PCVCs) in neonates: the HIP (Heparin Infusion for PCVC) studyPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, 775A, 600 University Ave, Toronto, Ontario, Canada M5G 1X5
Pediatrics 119:e284-91. 2007..Heparin use to prevent such complications and prolong the usability of peripherally inserted central venous catheters is inconclusive...
Contact dermatitis and bradycardia in a preterm infant given tetracaine 4% gelAnna Taddio
Department of Pharmacy and Population Health Sciences, The Hospital for Sick Children, Toronto, Canada
Ther Drug Monit 28:291-4. 2006..This is the first report of a serious skin reaction in a neonate treated with tetracaine. Based on these findings, tetracaine gel can continue to be used to treat pain in neonates with careful evaluation of the skin...
Improved outcomes of outborn preterm infants if admitted to perinatal centers versus freestanding pediatric hospitalsPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
J Pediatr 146:626-31. 2005..CONCLUSIONS: After adjustment for perinatal risks and admission illness severity, outborn infants had better outcomes if they were admitted to perinatal centers compared with freestanding pediatric hospitals...
Beta-endorphin concentration after administration of sucrose in preterm infantsAnna Taddio
Department of Pharmacy and Population Health Sciences, Research Institute, The Hospital for Sick Children, and Graduate Faculty of Pharmaceutical Sciences, University of Toronto, Canada
Arch Pediatr Adolesc Med 157:1071-4. 2003..Sucrose is an effective analgesic for procedural pain in preterm infants. It has been hypothesized that its analgesic effects are mediated by the release of endogenous opioid neurotransmitters such as beta-endorphin...
Caregivers' responses to pain in their children in the emergency departmentRyan W Smith
Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Toronto, Ontario, Canada
Arch Pediatr Adolesc Med 161:578-82. 2007..To explore physiological and anxiety responses of caregivers who witness a venipuncture being performed on their child and the effects of caregivers' responses on child pain and distress...
Pregnancy and neonatal outcomes of aboriginal women: a systematic review and meta-analysisPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada
Womens Health Issues 21:28-39. 2011..We conducted a systematic review and meta-analyses of pregnancy and neonatal outcomes among aboriginal women...
Knowledge translation of the HELPinKIDS clinical practice guideline for managing childhood vaccination pain: usability and knowledge uptake of educational materials directed to new parentsAnna Taddio
Clinical Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada
BMC Pediatr 13:23. 2013..The objectives of this study were to evaluate usability and effectiveness in terms of knowledge acquisition from the pamphlet and video in parents of newly born infants...
Incidence of chronic bilirubin encephalopathy in Canada, 2007-2008Michael Sgro
Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, 30 Bond St, 15CC 014, Toronto, ON, M5B1W8 Canada
Pediatrics 130:e886-90. 2012..The incidence of CBE in Canada is unknown. The objectives of this study were to establish the incidence of CBE in Canada and identify epidemiological and medical risk factors associated with its occurrence...
Maternal and neonatal outcomes in pregnancies complicated by bone and soft-tissue tumorsCynthia Maxwell
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Obstet Gynecol 104:344-8. 2004..Primary bone and soft-tissue tumors occur rarely in pregnancy. The objective of this study was to describe the outcome of a large cohort of pregnant patients with these rare tumors...
Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: a meta-analysisPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Ont
CMAJ 180:E99-108. 2009..We conducted a systematic review to examine the efficacy of prenatal supplementation with multimicronutrients on pregnancy outcomes...
Conditioning and hyperalgesia in newborns exposed to repeated heel lancesAnna Taddio
Department of Pharmacy, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
JAMA 288:857-61. 2002..Hospitalized infants undergo repeated invasive procedures. It is unknown whether cumulative experiences with pain lead to anticipatory pain behaviors and hyperalgesia...
Effect of indomethacin on closure of ductus arteriosus in very-low-birthweight neonatesSunit Godambe
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Ontario, Canada
Acta Paediatr 95:1389-93. 2006..CONCLUSION: Indomethacin is effective for PDA closure. The response rate diminished with subsequent courses. Early surfactant and severity of illness at admission were associated with non-responsiveness to indomethacin...
Mothers' beliefs about analgesia during childhood immunizationElena Parvez
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario
Paediatr Child Health 15:289-93. 2010....
A randomized control trial comparing immunogenicity, safety, and preference for self- versus nurse-administered intradermal influenza vaccineBrenda L Coleman
Mount Sinai Hospital, Department of Microbiology, Toronto, Canada
Vaccine 30:6287-93. 2012..Intradermally administered influenza vaccine is as immunogenic as intramuscular vaccine at a lower unit dose. New microinjection systems could allow self-administration of vaccine, potentially reducing the cost and inconvenience...
Agreement of carbon dioxide levels measured by arterial, transcutaneous and end tidal methods in preterm infants < or = 28 weeks gestationLucia Liz D Aliwalas
Department of Pediatrics, Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada
J Perinatol 25:26-9. 2005..Noninvasive monitoring methods cannot be substituted for PaCO(2) analyses in preterm infants during this critical period...
Breast milk as a source of late onset neonatal sepsisSunit Godambe
Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada M5G 1X8
Pediatr Infect Dis J 24:381-2. 2005..Breast milk should be considered as a potential source of infection in neonates with recurrent infections or when infections occur simultaneously in siblings...
Does the use of glycerin laxatives decrease feeding intolerance in preterm infants?Vibhuti Shah
Department of Paediatrics, Mount Sinai Hospital Department of Paediatrics and Department of Health Policy, Management and Evaluation, University of Toronto
Paediatr Child Health 16:e68-70. 2011..Glycerin laxatives are often prescribed in the neonatal population for meconium evacuation and to promote enteral feeding. However, the literature regarding their effectiveness has not been systematically reviewed...
Neonatal care in a Japanese NICU: notes based on a site visitNevart Chirinian
Mount SinaiHospital, Toronto, Canada
Neonatal Netw 31:89-96. 2012..Thus, visits such as this are beneficial in exchanging ideas and practices that may ultimately be mutually beneficial in reducing mortality and morbidity in a specific category of neonates...
Incidence and causes of severe neonatal hyperbilirubinemia in CanadaMichael Sgro
Department of Paediatrics, St Michael s Hospital, University of Toronto, Toronto, Ont
CMAJ 175:587-90. 2006..We conducted this study to estimate the incidence of severe neonatal hyperbilirubinemia in Canada and to determine underlying causes, improved knowledge of which would be valuable to help identify strategies for risk reduction...
Gabapentin improves postcesarean delivery pain management: a randomized, placebo-controlled trialALBERT MOORE
Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Anesth Analg 112:167-73. 2011..Gabapentin is effective for preventing and treating acute and chronic postoperative pain; however, it has not been described for use in cesarean delivery. We hypothesized that preoperative gabapentin would reduce postcesarean delivery pain...
Safety of benzodiazepines in newbornsEugene Ng
Department of Newborn and Developmental Paediatrics, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Ann Pharmacother 36:1150-5. 2002..Benzodiazepines are being used in neonatal intensive care units for sedation and control of seizures. However, anecdotal reports suggest that their use in infants may be associated with serious adverse effects (AEs)...
