Research Topics
| P S ShahSummaryAffiliation: Mount Sinai Hospital Country: Canada Publications
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Detail Information
Publications
Oesophageal perforation in preterm neonates: not an innocent bystanderP S Shah
Departments of Paediatrics, Mount Sinai Hospital, Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Paediatr Child Health 39:697-9. 2003..To compare the clinical course and neonatal outcomes of preterm infants with oesophageal perforation (OP)...
Do hyperoxaemia and hypocapnia add to the risk of brain injury after intrapartum asphyxia?G Klinger
Division of Neonatology, Hospital for Sick Children, Toronto, Ontario, Canada
Arch Dis Child Fetal Neonatal Ed 90:F49-52. 2005..Episodes of hyperoxaemia and hypocapnia, which may contribute to brain injury, occur unintentionally in severely asphyxiated neonates in the first postnatal hours...
Neonatal group B streptococcal disease: incidence, presentation, and mortalitySudqi Hamada
Department of Pediatrics, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada
J Matern Fetal Neonatal Med 21:53-7. 2008..To ascertain the incidence, and compare the clinical characteristics, laboratory parameters, and immediate mortality of neonates with early-onset (symptomatic and asymptomatic) and late-onset group B streptococcal (GBS) disease...- Seasonal variations in healthcare-associated infection in neonates in CanadaPrakesh S Shah
Department of Paediatrics, Rm 775 A, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada
Arch Dis Child Fetal Neonatal Ed 98:F65-9. 2013..To assess the seasonal pattern of healthcare-associated infections (HCAI) among neonates and to describe the trend of HCAI... - Prediction of survival without morbidity for infants born at under 33 weeks gestational age: a user-friendly graphical toolPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, 775A 600 University Avenue, Toronto, Canada
Arch Dis Child Fetal Neonatal Ed 97:F110-5. 2012..To develop models and a graphical tool for predicting survival to discharge without major morbidity for infants with a gestational age (GA) at birth of 22-32 weeks using infant information at birth... - Outcomes of preterm infants <29 weeks gestation over 10-year period in Canada: a cause for concern?P S Shah
Division of Neonatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada
J Perinatol 32:132-8. 2012..To compare risk-adjusted changes in outcomes of preterm infants <29 weeks gestation born in 1996 to 1997 with those born in 2006 to 2007... - Transfusion associated necrotizing enterocolitis: a meta-analysis of observational dataAdel Mohamed
Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada
Pediatrics 129:529-40. 2012..Our objective was to systematically review and meta-analyze the association between transfusion and NEC (TANEC), identify predictors of TANEC, and the assess impact of TANEC on outcomes... - Neonatal outcomes among multiple births ≤ 32 weeks gestational age: does mode of conception have an impact? A cohort studyVibhuti Shah
Department of Paediatrics, Room 775A, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada
BMC Pediatr 11:54. 2011..Therefore, the objective of our study was to compare composite outcome of mortality and severe neonatal morbidities amongst preterm multiple births ≤ 32 weeks gestation infant born following ART vs. SC... - Exposure to general anesthesia and risk of Alzheimer's disease: a systematic review and meta-analysisDallas P Seitz
Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
BMC Geriatr 11:83. 2011..The objective of this study is to systematically review the association between exposure to GA and risk of AD... - Influence of the maternal birth status on offspring: a systematic review and meta-analysisPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada
Acta Obstet Gynecol Scand 88:1307-18. 2009..Maternal low birth weight (LBW), preterm birth (PTB) and small-for-gestational age (SGA) birth status have been suggested as precursors for an infant being born LBW, PTB or SGA... - Induced termination of pregnancy and low birthweight and preterm birth: a systematic review and meta-analysesP S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada
BJOG 116:1425-42. 2009..Infection, mechanical trauma to the cervix leading to cervical incompetence and scarred tissue following curettage are suspected mechanisms... - Extensive cardiopulmonary resuscitation for VLBW and ELBW infants: a systematic review and meta-analysesP S Shah
Department of Pediatrics, Mount Sinai Hospital and University of Toronto, Ontario, Canada
J Perinatol 29:655-61. 2009..The long-term outcome of survivors was reported in a limited number of studies. Extensive CPR at birth or in the NICU for VLBW or ELBW infants was associated with higher risk of mortality... - Chest compression and/or epinephrine at birth for preterm infants <32 weeks gestational age: matched cohort study of neonatal outcomesP S Shah
Department of Pediatrics, Mount Sinai Hospital and University of Toronto, ON, Canada
J Perinatol 29:693-7. 2009..Studies of outcomes of preterm infants after the receipt of extensive cardiopulmonary resuscitation (CPR) at birth have yielded varied results... - Air pollution and birth outcomes: a systematic reviewPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Environ Int 37:498-516. 2011.... - Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: a meta-analysisPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Ont
CMAJ 180:E99-108. 2009..We conducted a systematic review to examine the efficacy of prenatal supplementation with multimicronutrients on pregnancy outcomes... - Intention to become pregnant and low birth weight and preterm birth: a systematic reviewPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, 775A 600 University Avenue, Toronto, Ontario, Canada
Matern Child Health J 15:205-16. 2011..50, 95% CI 1.41, 1.61) but not for mistimed (OR 1.36, 95% CI 0.96, 1.93) pregnancies. Unintended, unwanted, and mistimed pregnancies ending in a live birth are associated with a significantly increased risk of LBW and PTB... - Hypothermia: a systematic review and meta-analysis of clinical trialsPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Semin Fetal Neonatal Med 15:238-46. 2010..This analysis supports the use of hypothermia in reducing the risk of the mortality or moderate-to-severe neurodevelopmental disability in infants with moderate HIE... - Parity and low birth weight and preterm birth: a systematic review and meta-analysesPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Acta Obstet Gynecol Scand 89:862-75. 2010..To systematically review the risks of pregnancy outcomes among women of different parity... - Maternal marital status and birth outcomes: a systematic review and meta-analysesPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, 775A 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada
Matern Child Health J 15:1097-109. 2011..36, 95%CI 1.30-1.42) mothers. Meta-analyses of adjusted odds estimates confirmed these findings at marginally lower odds. Maternal unmarried status is associated with an increased risk of LBW, PTB and SGA births... - Maternal exposure to domestic violence and pregnancy and birth outcomes: a systematic review and meta-analysesPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Canada
J Womens Health (Larchmt) 19:2017-31. 2010..Our objective was to systematically review birth outcomes among women who experienced domestic violence... - Early opioid infusion and neonatal outcomes in preterm neonates ≤28 weeks' gestationPrakesh S Shah
Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada M5G1X5
Am J Perinatol 28:361-6. 2011..39, 95% CI 1.08, 1.79), and bronchopulmonary dysplasia (AOR 1.36, 95% CI 1.03, 1.79). Early exposure to opioid infusion in the first 3 days was associated with higher risk of adverse outcomes in extremely preterm infants... - Pregnancy and neonatal outcomes of aboriginal women: a systematic review and meta-analysisPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Canada
Womens Health Issues 21:28-39. 2011..We conducted a systematic review and meta-analyses of pregnancy and neonatal outcomes among aboriginal women... - Time courses of intrapartum asphyxia: neonatal characteristics and outcomesPrakesh S Shah
Division of Neonatology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Canada
Am J Perinatol 26:39-44. 2009..025). Long-term outcomes differ according to the time course of the insult; infants with combined time course had the worst outcome... - Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic reviewPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, and the Departments of Pediatrics and of Health Policy, Management and Evaluations, University of Toronto, Toronto, Ontario, Canada
Am J Obstet Gynecol 202:103-23. 2010..In conclusion, paternal characteristics including age, height, and birthweight are associated with LBW. Paternal occupational exposure and low levels of education may be associated with LBW; however, further studies are needed... - Current perspectives on the prevention and management of chronic lung disease in preterm infantsPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Paediatr Drugs 5:463-80. 2003..Future research priorities should be to identify strategies to prevent/treat inflammation and promote the healing processes in the injured lung. The long-term effects of lung-protective ventilation strategies need to be studied... - Multiorgan dysfunction in infants with post-asphyxial hypoxic-ischaemic encephalopathyP Shah
Department of Paediatrics, Mount Sinai Hospital, and University of Toronto, Toronto, Ontario, Canada
Arch Dis Child Fetal Neonatal Ed 89:F152-5. 2004..The theoretical concept behind MOD is the diving reflex (conservation of blood flow to vital organs at the cost of non-vital organs)... - Clinical characteristics and follow up of Down syndrome infants without congenital heart disease who presented with persistent pulmonary hypertension of newbornPrakesh S Shah
Division of Neonatology, Department of Critical Care, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
J Perinat Med 32:168-70. 2004.... - Postasphyxial hypoxic-ischemic encephalopathy in neonates: outcome prediction rule within 4 hours of birthPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Arch Pediatr Adolesc Med 160:729-36. 2006..To construct and validate a model and derive a simple rule that is usable in any birth location for the prediction of outcome of term infants with severe asphyxia... - Breastfeeding or breast milk for procedural pain in neonatesP S Shah
University of Toronto, Department of Paediatrics and Department of Health Policy, Management and Evaluation, Rm 775A, 600 University Avenue, Toronto, Ontario, Canada M5G 1XB
Cochrane Database Syst Rev 3:CD004950. 2006..Nonpharmacological measures (such as holding, swaddling, breastfeeding) and pharmacological measures (such as acetaminophen, sucrose and opioids) have been used for this purpose... - Postnatal growth failure in preterm infants: ascertainment and relation to long-term outcomePrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
J Perinat Med 34:484-9. 2006..Our objective was to identify measure of postnatal growth failure associated with long-term outcome in preterm infants born at < 28 weeks' gestation... - A randomized, controlled trial of heparin versus placebo infusion to prolong the usability of peripherally placed percutaneous central venous catheters (PCVCs) in neonates: the HIP (Heparin Infusion for PCVC) studyPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, 775A, 600 University Ave, Toronto, Ontario, Canada M5G 1X5
Pediatrics 119:e284-91. 2007..Heparin use to prevent such complications and prolong the usability of peripherally inserted central venous catheters is inconclusive... - Hypothermia to treat neonatal hypoxic ischemic encephalopathy: systematic reviewPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, and University of Toronto, Ontario, M5G 1X5, Canada
Arch Pediatr Adolesc Med 161:951-8. 2007..0-33.5 degrees C] or mild [>or=33.6 degrees C])... - Breastfeeding or breastmilk to alleviate procedural pain in neonates: a systematic reviewPrakesh S Shah
Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
Breastfeed Med 2:74-82. 2007..To (1) compare breastfeeding with control (placebo, no treatment, sucrose, glucose, pacifiers, or positioning) and (2) compare breastmilk with control for procedural pain in neonates... - Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infantsD M Campbell
Department of Paediatrics, Mt Sinai Hospital, University of Toronto, Toronto, ON, Canada
J Perinatol 26:546-9. 2006..To compare the feasibility of continuous positive airway pressure (CPAP) support generated by high flow nasal cannula with conventional CPAP for prevention of reintubation among preterm infants with a birth weight of <or=1,250 g... - Rupture of membranes before the age of viability and birth after the age of viability: comparison of outcomes in a matched cohort studyH Soylu
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
J Perinatol 30:645-9. 2010..To compare composite adverse outcome rate of infants <32 weeks gestational age (GA) who were born after preterm premature rupture of membranes (PPROM) at previable gestation to those born without PPROM... - Leukocytosis in very low birth weight neonates: associated clinical factors and neonatal outcomesI Morag
Shared Program in Neonatal Perinatal Medicine, University of Toronto, Toronto, ON, Canada
J Perinatol 28:680-4. 2008..Secondary objective was to compare outcomes between infants with early-onset (<or=72 h of age) and late-onset leukocytosis (>72 h)... - Unfractionated heparin for second trimester placental insufficiency: a pilot randomized trialJ C P Kingdom
Department of Obstetrics and Gynecology, Maternal Fetal Medicine Division, Mount Sinai Hospital, Toronto, ON, Canada
J Thromb Haemost 9:1483-92. 2011..To conduct a pilot randomized controlled trial of unfractionated heparin (UFH) in women considered at high risk of placental insufficiency in the second trimester... - Predictors of mortality and length of stay for neonates admitted to children's hospital neonatal intensive care unitsM A Berry
Department of Pediatrics, Montreal Children s Hospital and McGill University Health Centre, Montreal, QC, Canada
J Perinatol 28:297-302. 2008.... - Incorporation of femur length leads to underestimation of fetal weight in asymmetric preterm growth restrictionL K Proctor
Maternal Fetal Medicine Division, Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Ontario, Canada
Ultrasound Obstet Gynecol 35:442-8. 2010..To review the performance of a variety of biometry formulae for estimated fetal weight (EFW) in the management of severely growth restricted fetuses with abnormal umbilical artery Doppler at a single perinatal institution... - Recovery of metabolic acidosis in term infants with postasphyxial hypoxic-ischemic encephalopathyP S Shah
Division of Neonatology, The Hospital for Sick Children, Toronto, Canada
Acta Paediatr 92:941-7. 2003..The BD recovery rate of infants with adverse outcomes was similar to those with relatively good outcome. The different time patterns of asphyxial episode were not associated with differential recovery profiles... - Early-onset neonatal sepsis: rate and organism pattern between 2003 and 2008M Sgro
Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Canada
J Perinatol 31:794-8. 2011..The distribution of organisms in EONS helps to influence the appropriate type of antibiotic prophylaxis strategy during labor and the antibiotics used in neonates with suspected sepsis... - Safety and efficacy of early amino acids in preterm <28 weeks gestation: prospective observational comparisonK Kotsopoulos
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, Canada
J Perinatol 26:749-54. 2006..CONCLUSIONS: Early AA administration was not associated with any clinically significant adverse effects; it was associated with reduction in the incidence of sepsis and marginally effective in reducing time to regain birth weight... - Dexamethasone versus prednisone for induction therapy in childhood acute lymphoblastic leukemia: a systematic review and meta-analysisO Teuffel
Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
Leukemia 25:1232-8. 2011..However, DEX is also associated with more toxicity, and currently it remains unclear whether short-term superiority of DEX will also result in better overall survival... - Fruit and vegetable intake and bone health in women aged 45 years and over: a systematic reviewM Hamidi
Women s Health and Osteoporosis Programs, University Health Network, 200 Elizabeth Street, 7 Eaton North 228 A, Toronto, ON M5G 2C4, Canada
Osteoporos Int 22:1681-93. 2011..This is the first systematic review that specifically assessed this association and identified research gaps. The benefits of fruit and vegetables (F&V) on bone health remain unclear. Further studies are needed... - Quality of randomized clinical trials in juvenile idiopathic arthritisL Abrahamyan
The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada
Rheumatology (Oxford) 47:640-5. 2008..We evaluated the quality of randomized clinical trials (RCTs) of therapy for juvenile idiopathic arthritis (JIA) using an individual component approach and assessed temporal changes... - Breast milk as a source of late onset neonatal sepsisSunit Godambe
Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada M5G 1X8
Pediatr Infect Dis J 24:381-2. 2005..Breast milk should be considered as a potential source of infection in neonates with recurrent infections or when infections occur simultaneously in siblings... - Improved outcomes of outborn preterm infants if admitted to perinatal centers versus freestanding pediatric hospitalsPrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
J Pediatr 146:626-31. 2005..CONCLUSIONS: After adjustment for perinatal risks and admission illness severity, outborn infants had better outcomes if they were admitted to perinatal centers compared with freestanding pediatric hospitals... - Agreement of carbon dioxide levels measured by arterial, transcutaneous and end tidal methods in preterm infants < or = 28 weeks gestationLucia Liz D Aliwalas
Department of Pediatrics, Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada
J Perinatol 25:26-9. 2005..Noninvasive monitoring methods cannot be substituted for PaCO(2) analyses in preterm infants during this critical period... - Williams syndrome in a preterm infant with phenotype of Alagille syndromePrakesh S Shah
Department of Pediatrics, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Am J Med Genet A 146:2407-11. 2008..This case illustrates the importance of microarray analysis in diagnosing genetic conditions, especially in preterm babies whose facial and other clinical manifestations have not fully developed... - Neonatal renal venous thrombosis: clinical outcomes and prevalence of prothrombotic disordersStephen D Marks
Division of Nephrology, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Ontario, Canada
J Pediatr 146:811-6. 2005..Twelve of the 28 patients (43%) examined had prothrombotic abnormalities. CONCLUSION: Neonatal RVT is associated with significant renal morbidity and a high prevalence of prothrombotic abnormalities... - Overgrowth with severe developmental delay following IVF/ICSI: A newly recognized syndrome?Prakesh S Shah
Mount Sinai Hospital, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
Am J Med Genet A 140:1312-5. 2006..We propose that this is a previously unrecognized disorder. The potential role of ICSI/IVF in the pathogenesis of this condition is unknown. No imprinting defect at chromosome 11p15 was identified... - Effect of indomethacin on closure of ductus arteriosus in very-low-birthweight neonatesSunit Godambe
Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Ontario, Canada
Acta Paediatr 95:1389-93. 2006..CONCLUSION: Indomethacin is effective for PDA closure. The response rate diminished with subsequent courses. Early surfactant and severity of illness at admission were associated with non-responsiveness to indomethacin...