A J McGeer
Affiliation: Mount Sinai Hospital
- Cluster of cases of severe acute respiratory syndrome among Toronto healthcare workers after implementation of infection control precautions: a case seriesMarianna Ofner-Agostini
Nosocomial and Occupational Infections Section, Blood Safety and Surveillance, Health Care Acquired Infections Division, Public Health Agency of Canada, Tunney s Pasture, PL 0601E2, Ottawa, Canada K1A 0L2
Infect Control Hosp Epidemiol 27:473-8. 2006....
- Epidemiology of influenza-associated hospitalization in adults, Toronto, 2007/8S P Kuster
Department of Microbiology, Room 210, Mount Sinai Hospital, 600 University Ave, Toronto, Ontario M5G 1X5, Canada
Eur J Clin Microbiol Infect Dis 29:835-43. 2010..0 degrees C or admission is during the weeks of peak influenza activity...
- Optimizing antibiotics in residents of nursing homes: protocol of a randomized trialMark Loeb
Department of Pathology and Molecular Medicine, McMaster University Hamilton, ON, Canada
BMC Health Serv Res 2:17. 2002..Focus groups and semi-structured interviews with key informants will be used to assess the process of implementation and to identify key factors for sustainability...
- Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniaeDylan R Pillai
Department of Laboratory Medicine and Pathobiology, University of Toronto, ON, Canada
BMC Genomics 10:642. 2009..Canadian SPN isolates (1993-2008, n = 11,083) were serotyped and in vitro susceptibility tested. A subset of MDR 19A were multi-locus sequence typed (MLST) and representative isolates' whole genomes sequenced...
- Characterization of the quinolone resistant determining regions in clinical isolates of pneumococci collected in CanadaSamir N Patel
Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5, Canada
Ann Clin Microbiol Antimicrob 9:3. 2010....
- Vancomycin-resistant enterococciA J McGeer
Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada
Semin Respir Infect 15:314-26. 2000....
- Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, CanadaAllison Mcgeer
Toronto Medical Laboratories and Mount Sinai Hospital, Toronto, ON M5G 1X5 Canada
Clin Infect Dis 45:1568-75. 2007..We conducted a prospective cohort study to assess the impact of antiviral therapy on outcomes of patients hospitalized with influenza in southern Ontario, Canada...
- When should a diagnosis of influenza be considered in adults requiring intensive care unit admission? Results of population-based active surveillance in TorontoStefan P Kuster
Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada
Crit Care 15:R182. 2011....
- Diagnostic testing or empirical therapy for patients hospitalized with suspected influenza: what to do?Allison J McGeer
Department of Laboratory Medicine and Pathobiology, Medicine and Public Health Sciences, University of Toronto, Division of Infection Control, Mount Sinai Hospital, Toronto, Canada
Clin Infect Dis 48:S14-9. 2009..For patients hospitalized with suspected influenza, clinicians need to combine these approaches in order to optimize patient care...
- SARS outbreak in the Greater Toronto Area: the emergency department experienceBjug Borgundvaag
Mount Sinai Hospital, Toronto, Ont
CMAJ 171:1342-4. 2004
- Febrile respiratory illness in the intensive care unit setting: an infection control perspectiveMatthew P Muller
Department of Internal Medicine, Infectious Diseases Division, University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5
Curr Opin Crit Care 12:37-42. 2006....
- Adverse events associated with high-dose ribavirin: evidence from the Toronto outbreak of severe acute respiratory syndromeMatthew P Muller
Department of Microbiology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Pharmacotherapy 27:494-503. 2007..To distinguish adverse events related to ribavirin therapy from those attributable to severe acute respiratory syndrome (SARS), and to determine the rate of potential ribavirin-related adverse events...
- SARS among critical care nurses, TorontoMark Loeb
Department of Pathology and Molecualr Medicine, McMaster University, Hamilton, Ontario, Canada
Emerg Infect Dis 10:251-5. 2004..Risk was lower with consistent use of a N95 mask than with consistent use of a surgical mask. We conclude that activities related to intubation increase SARS risk and use of a mask (particularly a N95 mask) is protective...
- Surveillance for hospital outbreaks of invasive group a streptococcal infections in Ontario, Canada, 1992 to 2000Nick Daneman
University of Toronto, Mount Sinai Hospital, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Ann Intern Med 147:234-41. 2007..Streptococcus pyogenes can cause severe disease in the individual patient and dramatic hospital outbreaks...
- Severe acute respiratory syndrome. The Mount Sinai experiencePatricia Hynes-Gay
Mount Sinai Hospital, Toronto, Ontario
Can Nurse 99:16-9. 2003
- Health care workers and the initiation of treatment for latent tuberculosis infectionAndrea S Gershon
University of Toronto, Toronto, Ontario
Clin Infect Dis 39:667-72. 2004..The objective of this study was to determine whether health care workers were less likely than non-health care workers to initiate treatment for latent tuberculosis infection...
- Patient contact recall after SARS exposurePopy Dimoulas
Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Emerg Infect Dis 11:625-8. 2005..Healthcare workers reliably recalled events 6 months after exposure...
- Modeling transmission of methicillin-resistant Staphylococcus aureus among patients admitted to a hospitalJanet Raboud
Department of Public Health Sciences, University of Toronto, and University Health Network, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 26:607-15. 2005..To determine the impact of the screening test, nursing workload, handwashing rates, and dependence of handwashing on risk level of patient visit on methicillin-resistant Staphylococcus aureus (MRSA) transmission among hospitalized patients...
- West Nile virus infection in 2002: morbidity and mortality among patients admitted to hospital in southcentral OntarioCaitlin Pepperell
Divisions of Infectious Diseases, University of Toronto, Toronto, Ont, Canada
CMAJ 168:1399-405. 2003..INTERPRETATION: The 2002 WNV infection outbreak in Ontario caused serious morbidity and mortality in the subset of patients who had encephalitis or neuromuscular weakness severe enough to require hospital admission...
- Guillain-BarrÃ© syndrome after influenza vaccination in adults: a population-based studyDavid N Juurlink
Institute of Clinical Evaluative Sciences, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario
Arch Intern Med 166:2217-21. 2006..CONCLUSION: Influenza vaccination is associated with a small but significantly increased risk for hospitalization because of GBS...
- Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICUSangeeta Mehta
Interdepartmental Division of Critical Care Medicine, Mount Sinai Hospital, 600 University Ave, Suite 18 216, Toronto, Ontario, Canada M5G 1X5
Chest 130:1679-86. 2006..To describe the clinical features and outcome of patients with invasive group A streptococcal (GAS) infections admitted to the ICU...
- Clinical and epidemiologic features of group a streptococcal pneumonia in Ontario, CanadaMatthew P Muller
Department of Microbiology, Mount Sinai Hospital, 600 University Ave, Toronto, Ontario, Canada M5G 1X5
Arch Intern Med 163:467-72. 2003..Progression is rapid despite appropriate therapy. The incidence is similar to, and the case fatality rate higher than, that of necrotizing fasciitis...
- Clinical trials and novel pathogens: lessons learned from SARSMatthew P Muller
Mount Sinai Hospital, Toronto, Ontario, Canada
Emerg Infect Dis 10:389-94. 2004..Strategies to facilitate future clinical trials during outbreaks of unknown or novel pathogens are also presented...
- Severe acute respiratory syndrome (SARS) coronavirusMatthew P Muller
Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada
Semin Respir Crit Care Med 28:201-12. 2007..This review discusses the likelihood of another SARS pandemic and reviews the epidemiological and clinical features of the disease with an emphasis on the clinical presentation, diagnosis, and management of SARS...
- SARS--one year laterDonald E Low
Department of Microbiology, University Health Network-Mount Sinai Hospital and the University of Toronto, Toronto
N Engl J Med 349:2381-2. 2003
- Prevention of influenza and pneumococcal pneumonia in Canadian long-term care facilities: how are we doing?C G Stevenson
Department of Microbiology, Mount Sinai Hospital, University of Toronto, Toronto, Ont
CMAJ 164:1413-9. 2001..We describe the results of serial surveys of vaccination coverage and influenza outbreak management in Canadian long-term care facilities over the last decade...
- Infection control practices related to Clostridium difficile infection in acute care hospitals in CanadaDenise Gravel
Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ontario, Canada
Am J Infect Control 37:9-14. 2009..We carried out a survey to identify the infection prevention and control practices in place in Canadian hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP)...
- Impact of a mandatory infection control education program on nosocomial acquisition of methicillin-resistant Staphylococcus aureusTodd C Lee
University of Toronto, Canada
Infect Control Hosp Epidemiol 30:249-56. 2009..To assess the impact of an institution-wide infection control education program on the rate of transmission of methicillin-resistant Staphylococcus aureus (MRSA)...
- Antivirals and the control of influenza outbreaksSusy Hota
Division of Infection Control, The Mount Sinai Hospital, Toronto, Ontario, Canada
Clin Infect Dis 45:1362-8. 2007..If stockpiles are adequate, antiviral drugs are likely to be even more important in mitigating the impact of influenza transmission in health care institutions during the next influenza pandemic...
- Factors associated with acquisition of vancomycin-resistant enterococci (VRE) in roommate contacts of patients colonized or infected with VRE in a tertiary care hospitalQian Zhou
Department of Public Health Sciences, University of Toronto, Toronto, ON, Canada
Infect Control Hosp Epidemiol 29:398-403. 2008..Most nosocomial acquistion of vancomycin-resistant enterococci (VRE) is due to cross-transmission. We sought to identify risk factors for acquisition of VRE by roommates of patients colonized or infected with VRE...
- Focus group study of hand hygiene practice among healthcare workers in a teaching hospital in Toronto, CanadaJi Hyun Jang
Dalla Lana School of Public Health, University of Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 31:144-50. 2010..To understand the behavioral determinants of hand hygiene in our hospital...
- Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) acquisition in roommate contacts of patients colonized or infected with MRSA in an acute-care hospitalChristine Moore
Mt Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 29:600-6. 2008..To identify risk factors for acquisition of methicillin-resistant Staphylococcus aureus (MRSA) in patients exposed to an MRSA-colonized roommate...
- Clinical and epidemiologic features of methicillin-resistant Staphylococcus aureus in elderly hospitalized patientsAndrew E Simor
Department of Microbiology, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 26:838-41. 2005..The epidemiology and clinical features of these patients is distinct from that of younger patients...
- Patterns of handwashing behavior and visits to patients on a general medical ward of healthcare workersJanet Raboud
Department of Public Health Sciences, University of Toronto and the University Health Network, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 25:198-202. 2004..Education programs about hand hygiene may be more effective if patterns of care and levels of risk are incorporated into recommendations...
- Use of oseltamivir during influenza outbreaks in Ontario nursing homes, 1999-2000Susan K Bowles
Department of Pharmacy, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario
J Am Geriatr Soc 50:608-16. 2002..6%), cough (5, 0.7%), confusion (4, 0.5%) and nausea (4, 0.5%). CONCLUSIONS: Oseltamivir is safe and appears to be effective when used as treatment or prophylaxis to control outbreaks of influenza in older nursing home residents...
- A survey of physician's attitudes regarding management of severe group A streptococcal infectionsL Valiquette
Department of Microbiology and Infectious Diseases, Faculty of Medicine, University of Sherbrooke, Quebec, Ontario, Canada
Scand J Infect Dis 38:977-82. 2006..They also demonstrate that, although the majority of physicians recommend immunoglobulins, there is important variability between physician recommendations with regard to the indications of use, dose, and time of administration...
- Decreased prevalence of virulence factors among ciprofloxacin-resistant uropathogenic Escherichia coli isolatesS J Drews
Toronto Medical Laboratories and Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5
J Clin Microbiol 43:4218-20. 2005..0001; inpatient, 4% versus 76%, P < 0.0001) and that had a papEF genotype, genes encoding P fimbriae (outpatient, 30% versus 70%, P = 0.0004; inpatient, 26% versus 70%, P < 0.0001)...
- Detection and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates in Canada: results from the Canadian Nosocomial Infection Surveillance Program, 1995-2006Heather J Adam
Department of Laboratory Medicine and Pathobiology, University of Toronto, and Hospital for Sick Children, Toronto, Ontario, Canada
Antimicrob Agents Chemother 54:945-9. 2010..0; 95% CI, 1.2 to 7.4). There has been no evidence of vancomycin "MIC creep" in Canadian strains of methicillin (meticillin)-resistant S. aureus, and hVISA strains are currently uncommon...
- Risk factors for SARS transmission from patients requiring intubation: a multicentre investigation in Toronto, CanadaJanet Raboud
Division of Infectious Diseases, University Health Network, Toronto, Ontario, Canada
PLoS ONE 5:e10717. 2010..Considerable controversy resulted regarding which procedures and behaviours were associated with the greatest risk of SARS-CoV transmission...
- Facility-level correlates of antimicrobial use in nursing homesMark Loeb
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
Infect Control Hosp Epidemiol 25:173-6. 2004....
- Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitalsAndrew E Simor
Department of Microbiology, Sunnybrook Health Sciences Centre, B103 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
Antimicrob Agents Chemother 51:3880-6. 2007....
- Methicillin-resistant Staphylococcus aureus colonization or infection in Canada: National Surveillance and Changing Epidemiology, 1995-2007Andrew E Simor
Department of Microbiology, Sunnybrook Health Sciences Centre, Hospital for Sick Children, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 31:348-56. 2010..To determine the incidence and describe the changing epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) colonization or infection in Canadian hospitals from 1995-2007...
- Vancomycin-resistant enterococci in Canada: results from the Canadian nosocomial infection surveillance program, 1999-2005Marianna Ofner-Agostini
Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Sunnybrook Health Sciences Centre, Hospital for Sick Children, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 29:271-4. 2008..Although the incidence rate of VRE carriage in Canada is increasing, it remains very low...
- Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: a Canadian Nosocomial Infection Surveillance Program StudyDenise Gravel
Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, Ontario, Canada
Clin Infect Dis 48:568-76. 2009..We re-examined the incidence of HA CDI with an emphasis on patient outcomes...
- Antimicrobial susceptibilities of health care-associated and community-associated strains of methicillin-resistant Staphylococcus aureus from hospitalized patients in Canada, 1995 to 2008Andrew E Simor
Department of Microbiology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Antimicrob Agents Chemother 54:2265-8. 2010..Reduced susceptibility to glycopeptides was not identified...
- Effect of multivitamin and mineral supplementation on episodes of infection in nursing home residents: a randomized, placebo-controlled studyBarbara A Liu
Department of Medicine, Regional Geriatric Program of Toronto, Toronto, ON, Canada
J Am Geriatr Soc 55:35-42. 2007..To evaluate the effect of vitamin and mineral supplementation on infections in an elderly institutionalized population...
- Laboratory characterization of methicillin-resistant Staphylococcus aureus in Canadian hospitals: results of 5 years of National Surveillance, 1995-1999Andrew E Simor
Department of Microbiology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Canada
J Infect Dis 186:652-60. 2002..This study confirms that the epidemiology of MRSA in Canada is evolving, but most isolates at this time appear to belong to one of a small number of epidemic clones...
- Addressing the emergence of pediatric vaccination concerns: recommendations from a Canadian policy analysisKumanan Wilson
Department of Medicine, University of Toronto, Toronto, ON
Can J Public Health 97:139-41. 2006..However, such an investment is easy to justify given the benefits offered by pediatric vaccination and the ramifications of failing to maintain confidence in vaccination programs or missing a vaccine-related adverse event...
- Prevalence and characterization of invasive isolates of Streptococcus pyogenes with reduced susceptibility to fluoroquinolonesJeff Powis
Department of Microbiology, Toronto Medical Laboratories, Mount Sinai Hospital, 600 University Ave, Toronto, Ontario, Canada M5G 1X5
Antimicrob Agents Chemother 49:2130-2. 2005..None were nonsusceptible to levofloxacin. Two of 153 (1.3%) from 1992-1993 and 7 of 160 (4.4%) from 2003 had a levofloxacin MIC of 2 mug/ml; all nine had parC mutations, and eight were serotype M6...
- Methicillin-resistant Staphylococcus aureus in Canadian aboriginal peopleMarianna Ofner-Agostini
Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario, Canada
Infect Control Hosp Epidemiol 27:204-7. 2006....
- In vitro antimicrobial susceptibilities of Streptococcus pneumoniae clinical isolates obtained in Canada in 2002Jeff Powis
Department of Microbiology, Rm. 1487, Mount Sinai Hospital, 600 University Ave, Toronto, M5G 1X5 Ontario, Canada
Antimicrob Agents Chemother 48:3305-11. 2004..Nonsusceptibility to amoxicillin and ceftriaxone remains uncommon. Newer antimicrobials such as telithromycin and respiratory fluoroquinolones have excellent in vitro activity...
- Use of, effectiveness of, and attitudes regarding influenza vaccine among house staffRichard T Lester
Department of Medicine and Health Policy, University of Toronto, Toronto, Ontario, Canada
Infect Control Hosp Epidemiol 24:839-44. 2003..They were motivated mostly by self-protection and did report a benefit. Despite busy schedules and an unfounded fear of getting influenza symptoms from the vaccine, many thought the vaccine should be mandatory...
- The individual, environmental, and organizational factors that influence nurses' use of facial protection to prevent occupational transmission of communicable respiratory illness in acute care hospitalsKathryn Nichol
Centre for Research Expertise in Occupational Disease, University of Toronto and St Michael s Hospital, Toronto, Canada
Am J Infect Control 36:481-7. 2008..The objectives of this study were to describe the factors that influence nurses' decisions to use facial protection and to determine their relative importance in predicting compliance...
- Nursing home residents and Enterobacteriaceae resistant to third-generation cephalosporinsCarolyn Sandoval
McMaster University, Hamilton, Ontario, Canada
Emerg Infect Dis 10:1050-5. 2004..2 to 13.6) and log percentage of residents using gastrostomy tubes within the nursing home (adjusted OR 3.9, 95% CI 1.3 to 12.0) were associated with having a clinical isolate resistant to third-generation cephalosporins...
- Activities of new fluoroquinolones, ketolides, and other antimicrobials against blood culture isolates of viridans group streptococci from across Canada, 2000Andrea S Gershon
University of Toronto, Toronto, Canada
Antimicrob Agents Chemother 46:1553-6. 2002..06, 0.06, 0.12, and 0.03 microg/ml, respectively...
- Can routine laboratory tests discriminate between severe acute respiratory syndrome and other causes of community-acquired pneumonia?Matthew P Muller
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Clin Infect Dis 40:1079-86. 2005..Hematological and biochemical abnormalities, particularly lymphopenia, are common in patients with SARS...
- Severe group a streptococcal soft-tissue infections in Ontario: 1992-1996Abdu Sharkawy
Department of Microbiology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada M5G 1X5
Clin Infect Dis 34:454-60. 2002..Previously healthy patients without hypotension or NF may be considered for outpatient treatment...
- Beliefs and practices of Ontario midwives about influenza immunizationTodd Lee
Faculty of Medicine, 600 University Avenue, Room 1460, University of Toronto, Toronto, Ontario, Canada M5G 1X5
Vaccine 23:1574-8. 2005..001). If greater attention is not focused on promoting the utility of immunization to midwives, the success of population immunization programs may be compromised...
- Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian ExperienceBeate Sander
Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
Vaccine 28:6210-20. 2010....
- A cross-sectional study of maternity care providers' and women's knowledge, attitudes, and behaviours towards influenza vaccination during pregnancyAgnes Tong
Mount Sinai Hospital, Toronto, ON, Canada
J Obstet Gynaecol Can 30:404-10. 2008..Pregnant women are at increased risk of influenza-related complications, but research to examine barriers to maternal influenza vaccination has been limited and no studies have assessed the barriers to vaccinating pregnant women in Canada...
- Population-based surveillance for invasive pneumococcal disease in homeless adults in TorontoAgron Plevneshi
Toronto Invasive Bacterial Diseases Network, Toronto, Ontario, Canada
PLoS ONE 4:e7255. 2009..Identification of high-risk populations for serious infection due to S. pneumoniae will permit appropriately targeted prevention programs...
- Impact of public vaccination programs on adult vaccination rates: two examples from Ontario, CanadaWigdan Al-Sukhni
Faculty of Medicine, University of Toronto, Toronto, Canada
Vaccine 26:1432-7. 2008..Adult vaccination programs may be less successful than pediatric programs in achieving vaccine uptake, and require on-going assessment and promotion...
- Neonatal group B streptococcal disease: incidence, presentation, and mortalitySudqi Hamada
Department of Pediatrics, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada
J Matern Fetal Neonatal Med 21:53-7. 2008..To ascertain the incidence, and compare the clinical characteristics, laboratory parameters, and immediate mortality of neonates with early-onset (symptomatic and asymptomatic) and late-onset group B streptococcal (GBS) disease...
- Nutrition risk factors for survival in the elderly living in Canadian long-term care facilitiesJohane P Allard
Division of Gastroenterology and Nutrition, Department of Medicine, Toronto General Hospital, Toronto, Ontario, Canada
J Am Geriatr Soc 52:59-65. 2004..To determine the role of nutritional parameters in influencing the risk of mortality in institutionalized elderly...
- Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak unitsTimothy F Booth
National Microbiology Laboratory, Public Health Agency of Canada, Canadian Science Centre for Human and Animal Health, Winnipeg, Manitoba, Canada
J Infect Dis 191:1472-7. 2005....
- Hospital preparedness and SARSMona R Loutfy
McGill University, Montreal, Quebec, Canada
Emerg Infect Dis 10:771-6. 2004..We also make recommendations for other institutions to prepare for future outbreaks, regardless of their origin...
- Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infectionsStephen B Beres
Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
Proc Natl Acad Sci U S A 101:11833-8. 2004..Genome-wide analysis of population-based strain samples cultured from clinically well defined patients is crucial for understanding the molecular events underlying bacterial epidemics...
- Investigation of a nosocomial outbreak of severe acute respiratory syndrome (SARS) in Toronto, CanadaMonali Varia
Canadian Field Epidemiology Program, Health Canada, Ottawa, ON
CMAJ 169:285-92. 2003..There has been no evidence of further transmission within the hospital after the elapse of 2 full incubation periods (20 days)...
- Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, CanadaDavid A Boyd
Nosocomial Infections, National Microbiology Laboratory, 1015 Arlington St, Winnipeg, Manitoba, Canada
Antimicrob Agents Chemother 48:3758-64. 2004..coli strain isolated in India in 1999, revealed that the plasmids had several features in common, including an R100 backbone and several of the resistance genes, including bla(CTX-M-15), bla(TEM-1), bla(OXA-1), tetA, and aac(6')-Ib...
- SARS in healthcare facilities, Toronto and TaiwanL Clifford McDonald
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:777-81. 2004..Although these conclusions are based only on a retrospective analysis of events, applying the experiences of Toronto and Taiwan to SARS preparedness planning efforts will likely minimize future transmission within healthcare facilities...
- Clostridium difficile infection in hospitals: a brewing stormLouis Valiquette
CMAJ 171:27-9. 2004
- Alternative methods of estimating an incubation distribution: examples from severe acute respiratory syndromeBenjamin J Cowling
Department of Community Medicine, School of Public Health, University of Hong Kong, Pokfulam, Hong Kong
Epidemiology 18:253-9. 2007..Accurate and precise estimates of the incubation distribution of novel, emerging infectious diseases are vital to inform public health policy and to parameterize mathematical models...
- Human surveillance for West Nile virus infection in Ontario in 2000E Lee Ford-Jones
Division of Infectious Diseases, Hospital for Sick Children, University of Toronto, Ont
CMAJ 166:29-35. 2002..This affirms that identification of acute encephalitis on the basis of symptoms at the time of admission is often impossible...
- Coordinated response to SARS, Vancouver, CanadaDanuta M Skowronski
British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
Emerg Infect Dis 12:155-8. 2006..Baseline preparedness for pandemic threats may account for the absence of sustained transmission and fewer cases of SARS in Vancouver...
- Let him who desires peace prepare for war: United States hospitals and severe acute respiratory syndrome preparednessAllison Mcgeer
Clin Infect Dis 39:275-7. 2004
- Invasive group A streptococcal disease: risk factors for adultsStephanie H Factor
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 9:970-7. 2003..68, p=0.004), diabetes (RR=2.27, p=0.03), cardiac disease (RR=3.24, p=0.006), cancer (RR=3.54, p=0.006), and corticosteroid use (RR=5.18, p=0.03). Thus, host and environmental factors increased the risk for invasive GAS disease...
- Interpretation of diagnostic laboratory tests for severe acute respiratory syndrome: the Toronto experiencePatrick Tang
University of Toronto, Ont
CMAJ 170:47-54. 2004..In patients with SARS, specimens taken from the lower respiratory tract and stool samples test positive by means of RT-PCR more often than do samples taken from other areas...
- News in antimicrobial resistance: documenting the progress of pathogensAllison Mcgeer
Infect Control Hosp Epidemiol 25:97-8. 2004