Affiliation: Mount Sinai Hospital
- A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumorJ Couture
Department of Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada
Clin Genet 57:205-12. 2000..The natural history of the disease is variable between individuals, and surgical interventions have to be timed appropriately due to the frequent recurrences...