M O Woods

Summary

Affiliation: Memorial University of Newfoundland
Country: Canada

Publications

  1. pmc Genetic and mutational analyses of a large multiethnic Bardet-Biedl cohort reveal a minor involvement of BBS6 and delineate the critical intervals of other loci
    P L Beales
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 68:606-16. 2001
  2. ncbi Genetic heterogeneity of Bardet-Biedl syndrome in a distinct Canadian population: evidence for a fifth locus
    M O Woods
    Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland, A1B 3X9, Canada
    Genomics 55:2-9. 1999
  3. ncbi Canadian Bardet-Biedl syndrome family reduces the critical region of BBS3 (3p) and presents with a variable phenotype
    T L Young
    Faculty of Medicine, Memorial University of Newfoundland, St John s, Canada
    Am J Med Genet 78:461-7. 1998
  4. pmc A founder effect in the newfoundland population reduces the Bardet-Biedl syndrome I (BBS1) interval to 1 cM
    T L Young
    Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland A1B 3V9, Canada
    Am J Hum Genet 65:1680-7. 1999
  5. doi Impact of colonoscopic screening in male and female Lynch syndrome carriers with an MSH2 mutation
    S Stuckless
    Department of Clinical Epidemiology Department of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    Clin Genet 82:439-45. 2012
  6. doi Impact of gynecological screening in Lynch syndrome carriers with an MSH2 mutation
    S Stuckless
    Clinical Epidemiology Unit, Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    Clin Genet 83:359-64. 2013
  7. pmc The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease
    M O Woods
    Discipline of Genetics, Health Sciences Centre, St John s, Newfoundland, Canada
    Gut 59:1369-77. 2010
  8. pmc A fifth locus for Bardet-Biedl syndrome maps to chromosome 2q31
    T L Young
    Am J Hum Genet 64:900-4. 1999
  9. ncbi Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome
    N Katsanis
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Nat Genet 26:67-70. 2000

Collaborators

Detail Information

Publications9

  1. pmc Genetic and mutational analyses of a large multiethnic Bardet-Biedl cohort reveal a minor involvement of BBS6 and delineate the critical intervals of other loci
    P L Beales
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 68:606-16. 2001
    ..Our data also suggest that BBS6 is a minor contributor to the syndrome and that some BBS6 alleles may act in conjunction with mutations at other BBS loci to cause or modify the BBS phenotype...
  2. ncbi Genetic heterogeneity of Bardet-Biedl syndrome in a distinct Canadian population: evidence for a fifth locus
    M O Woods
    Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland, A1B 3X9, Canada
    Genomics 55:2-9. 1999
    ..Six families remain undetermined because of poor pedigree structure or inconclusive haplotype analyses. Six families were excluded from all four known BBS loci, indicating that there is at least a fifth BBS locus (BBS5)...
  3. ncbi Canadian Bardet-Biedl syndrome family reduces the critical region of BBS3 (3p) and presents with a variable phenotype
    T L Young
    Faculty of Medicine, Memorial University of Newfoundland, St John s, Canada
    Am J Med Genet 78:461-7. 1998
    ..However, formal IQ testing shows that these patients are of average intelligence. Haplotype analysis reduces the BBS3 critical region to a 6-cM interval between D3S1595-D3S1753...
  4. pmc A founder effect in the newfoundland population reduces the Bardet-Biedl syndrome I (BBS1) interval to 1 cM
    T L Young
    Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland A1B 3V9, Canada
    Am J Hum Genet 65:1680-7. 1999
    ..The LD data suggest that the BBS1 gene lies in a 1-Mb, sequence-ready region on chromosome 11q13, which should enable its identification...
  5. doi Impact of colonoscopic screening in male and female Lynch syndrome carriers with an MSH2 mutation
    S Stuckless
    Department of Clinical Epidemiology Department of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    Clin Genet 82:439-45. 2012
    ..CRC development may be further reduced by decreasing the screening interval to 1 year and improving quality of colonoscopy...
  6. doi Impact of gynecological screening in Lynch syndrome carriers with an MSH2 mutation
    S Stuckless
    Clinical Epidemiology Unit, Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    Clin Genet 83:359-64. 2013
    ....
  7. pmc The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease
    M O Woods
    Discipline of Genetics, Health Sciences Centre, St John s, Newfoundland, Canada
    Gut 59:1369-77. 2010
    ....
  8. pmc A fifth locus for Bardet-Biedl syndrome maps to chromosome 2q31
    T L Young
    Am J Hum Genet 64:900-4. 1999
  9. ncbi Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome
    N Katsanis
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Nat Genet 26:67-70. 2000
    ..Our data suggest that a complete loss of function of the MKKS product, and thus an inability to fold a range of target proteins, is responsible for the clinical manifestations of BBS...